Didanosine combined with Saquinavir

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Abortion Induced Other Serious 5/1/2001 28 Female 1/5/2006 Japan
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 61 Male 1/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/8/2001 Male 1/27/2006 Japan
Primary
Secondary
Concomitant
Pancytopenia Other Serious 10/1/1999 Male 3/13/2006 Physician Japan
Primary
Secondary
Concomitant
Hepatomegaly Other Serious 1/10/2006 55 Male 143 lb 4/10/2006 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/12/2003 Male 195 lb 4/12/2006 Canada
Primary
Secondary
Concomitant
Death Death 12/11/2004 Male 5/19/2006 United States
Primary
Concomitant
Retinal Detachment Hospitalization 9/10/2003 Female 6/1/2006 Portugal
Primary
Concomitant
Varices Oesophageal Other Serious 1/1/2003 65 Male 6/9/2006 Physician France
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/1998 Male 7/7/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/1998 Male 7/19/2006 Physician Japan
Primary
Secondary
Concomitant
Overdose Other Serious 12/1/1997 36 Male 7/18/2006 Spain
Primary
Secondary
Concomitant
Death Death 2/18/2004 Male 7/24/2006 United States
Primary
Concomitant
Anorectal Disorder Other Serious 7/1/2005 Male 8/11/2006 Physician Japan
Primary
Concomitant
Pancreatitis Acute Hospitalization 8/21/2002 Male 117 lb 8/11/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 7/1/2005 Male 8/14/2006 Physician United States
Primary
Secondary
Concomitant
Patella Fracture Other Serious 3/31/2003 Male 8/18/2006 Physician Japan
Primary
Secondary
Pancreatitis Acute Hospitalization 8/21/2002 Male 117 lb 8/22/2006 Physician Japan
Primary
Secondary
Concomitant
Sick Sinus Syndrome Other Serious 10/1/1999 Male 9/8/2006 Physician Japan
Primary
Secondary
Concomitant
Rib Fracture Other Serious 1/1/1996 Male 9/13/2006
Primary
Secondary
Concomitant
Viral Mutation Identified Other Serious Male 9/22/2006
Primary
Secondary
Thrombocytopenia Other Serious 6/22/2005 46 Male 143 lb 9/27/2006 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Viral Mutation Identified Other Serious Male 9/29/2006 Germany
Primary
Secondary
Concomitant
Hiv Infection Death Male 10/6/2006 Argentina
Primary
Concomitant
Viral Mutation Identified Other Serious Male 10/6/2006 Germany
Primary
Secondary
Concomitant
Retinal Detachment Hospitalization 9/10/2003 Female 10/6/2006 United States
Primary
Concomitant
Death Death 6/30/2005 Male 10/12/2006 United States
Primary
Concomitant
Death Death 9/13/2004 Male 10/26/2006 Brazil
Primary
Concomitant
Gait Disturbance Other Serious 36 Male 10/27/2006 Canada
Primary
Secondary
Concomitant
Interacting
Tremor Hospitalization 3/5/2001 0 Male 6 lb 12/4/2006 Consumer France
Primary
Secondary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Hospitalization 8/8/2000 2 Female 12/4/2006 Consumer France
Primary
Secondary
Thrombocythaemia Life Threatening 7/19/1999 Female 2 lb 12/5/2006 Physician France
Primary
Secondary
Concomitant
Uterine Cyst Hospitalization Female 7 lb 12/12/2006 Consumer France
Primary
Secondary
Concomitant
Splenic Rupture Hospitalization 41 Male 12/15/2006
Primary
Secondary
Sick Sinus Syndrome Other Serious 10/1/1999 Male 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 41 Male 12/29/2006
Primary
Secondary
Splenic Rupture Other Serious 41 Male 1/4/2007 Germany
Primary
Secondary
Rhinitis Other Serious 1/22/1998 Female 1/8/2007 Consumer France
Primary
Secondary
Splenic Rupture Other Serious 41 Male 1/8/2007 Germany
Primary
Secondary
Nephropathy Toxic Other Serious 51 Female 108 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 60 Male 154 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 11/10/1999 Male 2/22/2007 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 3/12/1998 63 Male 3/16/2007 Other Health Professional United States
Primary
Concomitant
Blood Triglycerides Increased Life Threatening 4/2/1998 49 Male 3/20/2007 Other Health Professional United States
Primary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 3/24/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 4/27/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 5/17/2007 Physician Japan
Primary
Secondary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Hospitalization 8/8/2000 Female 6/1/2007 Other Health Professional United States
Primary
Secondary
Nuclear Magnetic Resonance Imaging Abnormal Hospitalization 8/8/2000 2 Female 6/5/2007 Consumer France
Primary
Secondary
Unevaluable Event Hospitalization 9/9/1999 Female 7 lb 6/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocythaemia Other Serious 7/2/1999 Female 3 lb 6/6/2007 Physician United States
Primary
Secondary
Visual Disturbance Life Threatening 3/16/1998 Male 6/7/2007 Physician Japan
Primary
Secondary
Concomitant
Talipes Other Serious 9/9/1999 Female 7 lb 6/8/2007 Consumer France
Primary
Secondary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 6/15/2007 Physician Japan
Primary
Secondary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Hospitalization 8/8/2000 Female 6/15/2007 Other Health Professional United States
Primary
Secondary
Ventricular Extrasystoles Other Serious 7/30/2007 Other Health Professional Italy
Primary
Secondary
Sick Sinus Syndrome Other Serious 10/1/1999 Male 8/9/2007 Physician Japan
Primary
Secondary
Concomitant
Visceral Leishmaniasis Other Serious 1/1/2001 36 Female 8/10/2007 Italy
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/10/1999 Male 8/10/2007 Physician Japan
Primary
Secondary
Concomitant
Visceral Leishmaniasis Other Serious 1/1/2001 36 Female 8/10/2007 Italy
Primary
Concomitant
Monoparesis Hospitalization 6/14/2007 43 Male 136 lb 8/13/2007 Physician Spain
Primary
Concomitant
Monoparesis Hospitalization 6/14/2007 43 Male 136 lb 8/28/2007 Physician Spain
Primary
Concomitant
Pneumonia Hospitalization 8/21/2002 Male 117 lb 9/5/2007 Physician Japan
Primary
Secondary
Concomitant
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Concomitant
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Secondary
Concomitant
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Secondary
Drug Resistance Other Serious Female 9/10/2007 Czech Republic
Primary
Secondary
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Secondary
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Secondary
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Secondary
Pregnancy Congenital Anomaly Female 2 lb 9/13/2007 Other Health Professional United States
Primary
Secondary
Pregnancy Congenital Anomaly Female 2 lb 9/13/2007 Other Health Professional United States
Primary
Secondary
Pregnancy Congenital Anomaly Female 2 lb 9/14/2007 Other Health Professional United States
Primary
Secondary
Joint Dislocation Congenital Anomaly Female 2 lb 9/17/2007 United States
Primary
Secondary
Joint Dislocation Other Serious Female 2 lb 9/17/2007 United States
Primary
Secondary
Concomitant
Joint Dislocation Congenital Anomaly Female 20 lb 9/17/2007 United States
Primary
Secondary
Concomitant
Pregnancy Congenital Anomaly Female 2 lb 9/17/2007 Other Health Professional United States
Primary
Secondary
Joint Dislocation Congenital Anomaly Female 20 lb 9/21/2007 United States
Primary
Secondary
Concomitant
Joint Dislocation Congenital Anomaly Female 2 lb 9/25/2007 United States
Primary
Secondary
Joint Dislocation Other Serious Female 2 lb 9/27/2007 United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 1/1/2002 Male 10/5/2007 Other Health Professional France
Primary
Secondary
Concomitant
Purulence Other Serious 32 Male 10/5/2007 Physician Argentina
Primary
Secondary
Premature Baby Hospitalization 6/23/2003 Female 20 lb 10/29/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/10/1999 Male 10/29/2007 Physician Japan
Primary
Secondary
Concomitant
Metabolic Syndrome Disability 1/1/1999 40 Male 11/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1999 40 Male 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/21/2002 Male 117 lb 11/20/2007 Physician Japan
Primary
Secondary
Concomitant
Trisomy 18 Death Female 2 lb 12/18/2007 Physician France
Primary
Secondary
Homicide Death 6/30/2005 Male 2/6/2008 United States
Primary
Concomitant
Death Death 6/30/2005 Male 2/12/2008 United States
Primary
Concomitant
Gun Shot Wound Death 6/30/2005 Male 2/27/2008 United States
Primary
Concomitant
Respiratory Failure Other Serious 2/12/2008 Male 128 lb 2/29/2008 Chile
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 45 Male 3/28/2008 Other Health Professional United States
Primary
Secondary
Sex Hormone Binding Globulin Decreased Other Serious 49 Male 3/31/2008
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 2/12/2008 Male 128 lb 6/9/2008 Chile
Primary
Concomitant
Ventricular Extrasystoles Other Serious 6/13/2008 Other Health Professional United States
Primary
Secondary
Renal Failure Chronic Hospitalization 46 Male 6/13/2008 Canada
Primary
Concomitant
Rash Other Serious 4/3/2008 Female 7/10/2008 Physician United Kingdom
Primary
Concomitant
Twin Pregnancy Other Serious 25 Female 7/25/2008 Other Health Professional United States
Primary
Secondary
Pneumonia Hospitalization 8/21/2002 Male 117 lb 8/11/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Aplasia Congenital Anomaly 8/14/2008 United States
Primary
Secondary
Renal Aplasia Congenital Anomaly 8/20/2008 United States
Primary
Secondary
Renal Aplasia Congenital Anomaly 8/20/2008 Spain
Primary
Secondary
Renal Aplasia Congenital Anomaly 9/4/2008 Spain
Primary
Secondary
Sepsis Other Serious 3/5/2008 Male 10/13/2008 Other Health Professional France
Primary
Concomitant
Vaginitis Gardnerella Other Serious 5/1/2008 41 Female 11/6/2008 Other Health Professional France
Primary
Secondary
Liver Function Test Abnormal Other Serious 40 Male 1/9/2009
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2001 42 Female 90 lb 3/20/2009 France
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 37 Male 4/15/2009 Other Health Professional United States
Primary
Secondary
Lipodystrophy Acquired Other Serious 40 Male 4/15/2009 Other Health Professional United States
Primary
Secondary
Weight Decreased Other Serious 33 Female 4/27/2009 Consumer Brazil
Primary
Secondary
Concomitant
Nodular Regenerative Hyperplasia Other Serious 40 Male 5/7/2009
Primary
Secondary
Liver Disorder Other Serious 45 Male 5/8/2009
Primary
Secondary
Liver Disorder Other Serious 42 Male 5/8/2009
Primary
Secondary
Unevaluable Event Hospitalization 9/9/1999 Female 7 lb 5/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Abortion Spontaneous Other Serious Female 6/4/2009 United States
Primary
Concomitant
Treatment Failure Other Serious 7/31/2009 Other Health Professional Denmark
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 54 Male 7/31/2009
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 7/31/2009
Primary
Secondary
Treatment Failure Other Serious 8/3/2009 Other Health Professional Denmark
Primary
Secondary
Treatment Failure Other Serious 8/3/2009 Other Health Professional Denmark
Primary
Secondary
Sick Sinus Syndrome Other Serious 10/1/1999 Male 8/4/2009 Japan
Primary
Secondary
Concomitant
Sick Sinus Syndrome Other Serious 4/1/2001 Male 8/5/2009 Japan
Primary
Secondary
Concomitant
Retinitis Life Threatening 2/7/2000 Male 8/10/2009 Physician Japan
Primary
Secondary
Concomitant
Nodular Regenerative Hyperplasia Other Serious Male 8/24/2009
Primary
Secondary
Nodular Regenerative Hyperplasia Other Serious Male 8/24/2009
Primary
Secondary
Chronic Hepatic Failure Other Serious Male 8/24/2009
Primary
Secondary
Varices Oesophageal Hospitalization 57 Male 8/27/2009
Primary
Secondary
Vascular Injury Hospitalization 48 Female 8/27/2009
Primary
Secondary
Varices Oesophageal Hospitalization 43 Female 8/27/2009
Primary
Secondary
Parkinsonism Other Serious 50 Male 9/3/2009
Primary
Secondary
Pulmonary Hypertension Other Serious 48 Female 9/4/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 57 Male 9/4/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 43 Female 9/4/2009 Other Health Professional Spain
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 9/8/2009 Consumer United States
Primary
Secondary
Portal Hypertension Other Serious 57 Male 9/9/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 48 Female 9/9/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 43 Female 9/9/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 57 Male 9/14/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 48 Female 9/14/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 43 Female 9/14/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertensive Gastropathy Other Serious 57 Male 9/11/2009 Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 57 Male 9/17/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 48 Female 9/17/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 43 Female 9/17/2009 Other Health Professional Spain
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 54 Male 9/17/2009 Other Health Professional Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 9/17/2009 Other Health Professional Canada
Primary
Secondary
Varices Oesophageal Other Serious 48 Female 9/11/2009
Primary
Secondary
Splenomegaly Other Serious 43 Female 9/11/2009
Primary
Secondary
Portal Hypertensive Gastropathy Other Serious 57 Male 9/11/2009
Primary
Secondary

Drug Data