Saquinavir combined with Tenofovir

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Tubular Necrosis Hospitalization 61 Male 1/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 7/9/2004 Male 1/23/2006 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/8/2001 Male 1/27/2006 Japan
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 2/1/1999 41 Male 3/6/2006 Physician Germany
Primary
Secondary
Concomitant
Toxoplasmosis Disability 37 Male 143 lb 3/22/2006 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 4/1/2002 Male 139 lb 3/27/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1998 42 Male 143 lb 3/27/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Gain Poor Other Serious 1/1/2001 Male 181 lb 3/27/2006 Physician Germany
Primary
Secondary
Concomitant
Toxoplasmosis Disability 37 Male 3/29/2006 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 4/1/2002 Male 3/29/2006 Physician Germany
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 2/10/2006 46 Male 3/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Other Serious 1/6/2004 Male 4/17/2006 Other Health Professional Germany
Primary
Secondary
Pyrexia Other Serious 1/1/1998 Male 154 lb 4/17/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/1998 Male 139 lb 5/8/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Tuberculosis Other Serious 1/1/2001 Male 176 lb 5/8/2006 Physician Germany
Primary
Secondary
Concomitant
Viral Load Increased Other Serious 4/1/1999 Male 110 lb 5/8/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/1998 Male 139 lb 5/18/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Death Death 12/11/2004 Male 5/19/2006 United States
Primary
Concomitant
Staphylococcal Infection Other Serious 7/9/2004 Male 5/26/2006 Physician Japan
Primary
Secondary
Concomitant
Retinal Detachment Hospitalization 9/10/2003 Female 6/1/2006 Portugal
Primary
Concomitant
Viral Mutation Identified Death 11/1/2001 39 Male 6/20/2006
Primary
Secondary
Death Death 2/18/2004 Male 7/24/2006 United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 8/21/2002 Male 117 lb 8/11/2006 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 7/9/2004 Male 8/21/2006 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 8/21/2002 Male 117 lb 8/22/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 39 Male 8/30/2006 Physician Thailand
Primary
Concomitant
Transaminases Increased Other Serious 7/1/2006 40 Male 9/1/2006 Physician Brazil
Primary
Concomitant
Rib Fracture Other Serious 1/1/1996 Male 9/13/2006
Primary
Secondary
Concomitant
Pneumonitis Other Serious 9/1/1997 46 Male 10/3/2006
Primary
Secondary
Hiv Infection Death Male 10/6/2006 Argentina
Primary
Concomitant
Retinal Detachment Hospitalization 9/10/2003 Female 10/6/2006 United States
Primary
Concomitant
Death Death 6/30/2005 Male 10/12/2006 United States
Primary
Concomitant
Weight Decreased Other Serious 12/28/1999 Male 1/25/2007 Physician Japan
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 56 Male 161 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 51 Female 108 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Hypokalaemia Other Serious 40 Male 134 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 60 Male 154 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Visual Disturbance Life Threatening 3/16/1998 Male 4/27/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 5/17/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 6/7/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 6/15/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/28/1999 Male 6/15/2007 Physician Japan
Primary
Secondary
Concomitant
Gun Shot Wound Death 6/30/2005 Male 2/27/2008 United States
Primary
Concomitant
Sex Hormone Binding Globulin Decreased Other Serious 49 Male 3/31/2008
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/21/2002 Male 117 lb 8/11/2008 Physician Japan
Primary
Secondary
Concomitant
Osteomyelitis Other Serious 38 Male 8/12/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 9/10/1999 Male 10/3/2008 Physician
Primary
Secondary
Concomitant
Pruritus Other Serious 30 Female 11/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Pruritus Other Serious 8/24/2007 30 Female 12/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Intra-uterine Death Other Serious 38 Female 12/26/2008 Other Health Professional United States
Primary
Secondary
Hepatotoxicity Other Serious 37 Male 4/15/2009 Other Health Professional United States
Primary
Secondary
Lipodystrophy Acquired Other Serious 40 Male 4/15/2009 Other Health Professional United States
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Hospitalization 16 Female 4/23/2009 Physician United States
Primary
Secondary
Liver Disorder Other Serious 45 Male 5/8/2009
Primary
Secondary
Liver Disorder Other Serious 42 Male 5/8/2009
Primary
Secondary
Weight Decreased Other Serious 12/28/1999 Male 6/25/2009 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/1/2007 63 Male 7/24/2009 Other Health Professional Germany
Primary
Secondary
Myelodysplastic Syndrome Hospitalization 6/1/2007 63 Male 7/28/2009 Other Health Professional Germany
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 54 Male 7/31/2009
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 7/31/2009
Primary
Secondary
Varices Oesophageal Hospitalization 57 Male 8/27/2009
Primary
Secondary
Vascular Injury Hospitalization 48 Female 8/27/2009
Primary
Secondary
Varices Oesophageal Hospitalization 43 Female 8/27/2009
Primary
Secondary
Pulmonary Hypertension Other Serious 43 Female 9/4/2009 Other Health Professional Spain
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 9/8/2009 Consumer United States
Primary
Secondary
Portal Hypertension Other Serious 57 Male 9/9/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 48 Female 9/9/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 43 Female 9/9/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 57 Male 9/14/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 48 Female 9/14/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 43 Female 9/14/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertensive Gastropathy Other Serious 57 Male 9/11/2009 Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 43 Female 9/17/2009 Other Health Professional Spain
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 9/17/2009 Other Health Professional Canada
Primary
Secondary
Varices Oesophageal Other Serious 48 Female 9/11/2009
Primary
Secondary
Portal Hypertensive Gastropathy Other Serious 57 Male 9/11/2009
Primary
Secondary
Portal Hypertension Other Serious 57 9/21/2009 Other Health Professional Spain
Primary
Secondary
Splenomegaly Other Serious 43 Female 9/28/2009
Primary
Secondary
Splenomegaly Other Serious 48 Female 9/28/2009
Primary
Secondary
Splenomegaly Other Serious 57 Male 9/28/2009
Primary
Secondary
Portal Hypertension Other Serious 48 Female 10/6/2009 Physician Spain
Primary
Secondary
Portal Hypertension Other Serious 43 Female 10/6/2009 Physician Spain
Primary
Secondary
Parkinsonism Other Serious 53 Male 10/8/2009 Other Health Professional Australia
Primary
Secondary
Parkinsonism Other Serious 53 Male 10/13/2009 Physician Australia
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 10/7/2009
Primary
Secondary
Parkinson's Disease Other Serious 53 10/14/2009 Physician Australia
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 10/19/2009 Other Health Professional Canada
Primary
Secondary
Parkinsonism Other Serious 53 Male 10/20/2009 Other Health Professional United States
Primary
Secondary
Rapid Eye Movements Sleep Abnormal Other Serious 53 Male 10/16/2009 Physician Australia
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 10/22/2009 Physician United States
Primary
Secondary
Tuberculin Test Positive Other Serious 39 Male 205 lb 10/23/2009 Physician Poland
Primary
Secondary
Concomitant
Parkinsonism Other Serious 53 Male 10/28/2009 Other Health Professional United States
Primary
Secondary
Tuberculin Test Positive Other Serious 39 Male 11/4/2009 Physician Poland
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 2/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Treatment Failure Other Serious 2/1/2005 33 Male 2/26/2010 Other Health Professional France
Primary
Secondary
Parkinsonism Other Serious 53 Male 3/2/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 3/3/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 3/4/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 3/4/2010 Other Health Professional United States
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 3/4/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 3/4/2010 Consumer United States
Primary
Secondary
Parkinsonism Other Serious 53 Male 3/5/2010 Other Health Professional United States
Primary
Secondary
Visual Impairment Life Threatening 3/16/1998 Male 3/5/2010 Japan
Primary
Secondary
Concomitant
Treatment Failure Other Serious 2/1/2005 33 Male 3/4/2010 Other Health Professional France
Primary
Secondary
Visual Impairment Life Threatening 3/16/1998 Male 3/15/2010 Japan
Primary
Secondary
Concomitant
Parkinsonism Other Serious 53 Male 3/18/2010 Other Health Professional United States
Primary
Secondary
Virologic Failure Other Serious 33 Male 150 lb 3/26/2010 Other Health Professional Cote D'ivoire
Primary
Secondary
Virologic Failure Hospitalization Male 3/26/2010 Physician Brazil
Primary
Secondary
Virologic Failure Other Serious 49 Male 4/2/2010 Consumer United States
Primary
Secondary
Virologic Failure Other Serious 6/1/2007 44 Male 4/14/2010 Physician United States
Primary
Secondary
Virologic Failure Hospitalization Male 4/16/2010 Physician United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/14/2010 Other Health Professional United States
Primary
Secondary
Rash Other Serious 5/1/2005 34 Female 5/17/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 5/18/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/28/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 6/25/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Required Intervention 52 Male 6/14/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 7/22/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 8/16/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 8/16/2010 Other Health Professional United States
Primary
Secondary
Weight Decreased Hospitalization 11/1/2007 40 Male 140 lb 2/15/2010 Physician United States
Primary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 10/6/2010 Other Health Professional United States
Primary
Secondary
Virologic Failure Other Serious 62 Male 10/14/2010 Consumer Germany
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 10/18/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 10/18/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 11/1/2010 Consumer United States
Primary
Secondary
Developmental Delay Congenital Anomaly 3/12/2011 Physician France
Primary
Secondary
Blood Creatinine Increased Other Serious 61 Male 4/7/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 46 Male 4/19/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Osteoporosis Other Serious 31 Female 176 lb 11/23/2011 Other Health Professional Poland
Primary
Secondary
Nausea Disability 3/16/1998 22 Male 12/13/2011 Physician Japan
Primary
Secondary
Concomitant
Osteoporosis Other Serious 31 Female 176 lb 1/5/2012 Other Health Professional Poland
Primary
Secondary
Rapid Eye Movements Sleep Abnormal Other Serious 53 Male 7/8/2013 Other Health Professional Country Not Specified
Primary
Secondary
Liver Disorder Death 10/22/2002 47 Male 1/29/2013 Physician Country Not Specified
Primary
Secondary
Concomitant
Drug Interaction Other Serious 60 Male 10/25/2012 Country Not Specified
Primary
Interacting
Herpes Simplex Other Serious 60 Male 10/18/2012 Other Health Professional Be
Primary
Secondary
Varices Oesophageal Other Serious 53 Male 11/8/2012 Other Health Professional Country Not Specified
Primary
Secondary
Skin Atrophy Other Serious 60 Male 11/9/2012 Physician Be
Primary
Secondary
Myocardial Infarction Other Serious 54 Female 11/30/2012 Physician Us
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 54 Female 12/3/2012 Physician Us
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 54 Female 12/5/2012 Physician Us
Primary
Secondary
Concomitant
Herpes Simplex Other Serious 60 Male 154 lb 12/28/2012 Other Health Professional Country Not Specified
Primary
Secondary
Interacting
White Blood Cell Count Increased Hospitalization 54 Female 12/18/2012 Us
Primary
Secondary
Vomiting Other Serious 2005 41 Female 3/7/2013 Consumer Us
Primary
Secondary
Vomiting Other Serious 2005 41 Female 3/11/2013 Consumer Us
Primary
Secondary
Myocardial Infarction Other Serious 54 Female 2/19/2013 Consumer Us
Primary
Secondary
Concomitant
Drug Metabolising Enzyme Test Abnormal Other Serious 45 Male 194 lb 4/9/2013 Physician Country Not Specified
Primary
Interacting
Drug Resistance Death 10 Male 6/14/2013 Other Health Professional In
Primary
Secondary
Treatment Noncompliance Hospitalization 1998 36 Male 9/3/2013 Physician De
Primary
Secondary
Concomitant
Visual Impairment Disability 3/16/1998 23 Male 131 lb 7/30/2013 Physician Country Not Specified
Primary
Secondary
Concomitant

Drug Data