Efavirenz combined with Saquinavir

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Abortion Induced Other Serious 5/1/2001 28 Female 1/5/2006 Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 5/31/1999 52 Male 1/18/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/8/2001 Male 1/27/2006 Japan
Primary
Secondary
Concomitant
Sensory Disturbance Other Serious 34 Male 1/30/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Diabetic Ketoacidosis Hospitalization 48 Female 3/9/2006 Denmark
Primary
Secondary
Pancytopenia Other Serious 10/1/1999 Male 3/13/2006 Physician Japan
Primary
Secondary
Concomitant
Spinal Osteoarthritis Hospitalization 11/15/2003 Male 213 lb 4/13/2006
Primary
Concomitant
Oral Candidiasis Other Serious 1/1/2001 Male 198 lb 5/8/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Viral Mutation Identified Death 11/1/2001 39 Male 6/20/2006
Primary
Secondary
White Blood Cell Count Decreased Other Serious 12/4/1998 Male 7/7/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/1998 Male 7/19/2006 Physician Japan
Primary
Secondary
Concomitant
Oral Discomfort Other Serious 1/1/2005 42 Female 7/20/2006 Other Health Professional Spain
Primary
Secondary
Oral Discomfort Other Serious 1/1/2005 42 Female 7/31/2006 Other Health Professional Spain
Primary
Secondary
Nausea Hospitalization 49 Female 7/24/2006 United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 7/1/2006 40 Male 9/1/2006 Physician Brazil
Primary
Concomitant
Sick Sinus Syndrome Other Serious 10/1/1999 Male 9/8/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/22/2005 46 Male 143 lb 9/27/2006 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Death Death 9/13/2004 Male 10/26/2006 Brazil
Primary
Concomitant
Hyponatraemia Other Serious 49 Female 10/27/2006 Canada
Primary
Secondary
Concomitant
Interacting
Uterine Cyst Hospitalization Female 7 lb 12/12/2006 Consumer France
Primary
Secondary
Concomitant
Sick Sinus Syndrome Other Serious 10/1/1999 Male 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/28/1999 Male 1/25/2007 Physician Japan
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 51 Female 108 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Hypokalaemia Other Serious 40 Male 134 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 11/10/1999 Male 2/22/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 3/24/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 4/27/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 5/17/2007 Physician Japan
Primary
Secondary
Concomitant
Paraparesis Other Serious 5/14/2007 54 Female 5/25/2007 Consumer Botswana
Primary
Secondary
Visual Disturbance Life Threatening 3/16/1998 Male 6/7/2007 Physician Japan
Primary
Secondary
Concomitant
Talipes Other Serious 9/9/1999 Female 7 lb 6/8/2007 Consumer France
Primary
Secondary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 6/15/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/28/1999 Male 6/15/2007 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Other Serious 6/16/1998 Male 6/19/2007 Physician Japan
Primary
Secondary
Concomitant
Sick Sinus Syndrome Other Serious 10/1/1999 Male 8/9/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/10/1999 Male 8/10/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/10/1999 Male 10/29/2007 Physician Japan
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1999 40 Male 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 5/31/1999 52 Male 2/27/2008 Physician United States
Primary
Secondary
Concomitant
Sex Hormone Binding Globulin Decreased Other Serious 49 Male 3/31/2008
Primary
Secondary
Concomitant
Lymphoma Other Serious 6/16/1998 Male 4/30/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/28/1999 Male 6/27/2008 Physician Japan
Primary
Secondary
Concomitant
Stomach Mass Hospitalization 4/14/2006 Male 7/3/2008 Physician Japan
Primary
Secondary
Concomitant
Stomach Mass Hospitalization 4/14/2006 Male 8/6/2008 Physician Japan
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Other Serious 2 lb 8/8/2008 United States
Primary
Secondary
Uterine Disorder Death 2/1/2007 3 lb 8/13/2008 Physician Germany
Primary
Secondary
Concomitant
Premature Rupture Of Membranes Other Serious 2/1/2007 30 Female 8/15/2008 Germany
Primary
Secondary
Concomitant
Premature Rupture Of Membranes Other Serious 2/1/2007 30 Female 8/25/2008 United States
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Other Serious 2 lb 8/26/2008 United States
Primary
Secondary
Stomach Mass Hospitalization 4/14/2006 Male 9/3/2008 Physician Japan
Primary
Secondary
Concomitant
Neural Tube Defect Congenital Anomaly 12/1/2007 10/1/2008 United States
Primary
Secondary
Renal Impairment Hospitalization 9/10/1999 Male 10/3/2008 Physician
Primary
Secondary
Concomitant
Neural Tube Defect Congenital Anomaly 12/1/2007 10/16/2008 United States
Primary
Secondary
Vaginitis Gardnerella Other Serious 5/1/2008 41 Female 11/6/2008 Other Health Professional France
Primary
Secondary
Neural Tube Defect Congenital Anomaly 11/21/2008 United States
Primary
Secondary
Neural Tube Defect Congenital Anomaly 12/5/2008 United States
Primary
Secondary
Urogenital Disorder Congenital Anomaly 12/19/2008 Physician Germany
Primary
Secondary
Liver Function Test Abnormal Other Serious 40 Male 1/9/2009
Primary
Secondary
Concomitant
Uterine Disorder Death 2/1/2007 3 lb 3/3/2009 Physician Germany
Primary
Secondary
Concomitant
Neural Tube Defect Congenital Anomaly 3/6/2009 United States
Primary
Secondary
Systemic Inflammatory Response Syndrome Other Serious 2 lb 3/6/2009 United States
Primary
Secondary
Lipodystrophy Acquired Other Serious 40 Male 4/15/2009 Other Health Professional United States
Primary
Secondary
Systemic Inflammatory Response Syndrome Other Serious 2 lb 7/20/2009 United States
Primary
Secondary
Myelodysplastic Syndrome Hospitalization 63 Male 7/21/2009 Other Health Professional Germany
Primary
Secondary
Respiratory Failure Hospitalization 1/1/2007 63 Male 7/24/2009 Other Health Professional Germany
Primary
Secondary
Myelodysplastic Syndrome Hospitalization 6/1/2007 63 Male 7/28/2009 Other Health Professional Germany
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 7/31/2009
Primary
Secondary
Myelodysplastic Syndrome Hospitalization 63 Male 8/3/2009 Other Health Professional Germany
Primary
Secondary
Sick Sinus Syndrome Other Serious 10/1/1999 Male 8/4/2009 Japan
Primary
Secondary
Concomitant
Sick Sinus Syndrome Other Serious 4/1/2001 Male 8/5/2009 Japan
Primary
Secondary
Concomitant
Lymphoma Other Serious 6/16/1998 Male 8/7/2009 Physician Japan
Primary
Secondary
Concomitant
Retinitis Life Threatening 2/7/2000 Male 8/10/2009 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Other Serious 9/11/2000 Male 8/11/2009 Physician Japan
Primary
Secondary
Concomitant
Nodular Regenerative Hyperplasia Other Serious Male 8/24/2009
Primary
Secondary
Nodular Regenerative Hyperplasia Other Serious Male 8/24/2009
Primary
Secondary
Varices Oesophageal Hospitalization 57 Male 8/27/2009
Primary
Secondary
Pulmonary Hypertension Other Serious 57 Male 9/4/2009 Other Health Professional Spain
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 9/8/2009 Consumer United States
Primary
Secondary
Portal Hypertension Other Serious 57 Male 9/9/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 57 Male 9/14/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 57 Male 9/17/2009 Other Health Professional Spain
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 9/17/2009 Other Health Professional Canada
Primary
Secondary
Portal Hypertensive Gastropathy Other Serious 57 Male 9/11/2009
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 9/23/2009 Other Health Professional Canada
Primary
Secondary
Portal Hypertension Other Serious 57 9/21/2009 Other Health Professional Spain
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 9/29/2009 Other Health Professional Canada
Primary
Secondary
Splenomegaly Other Serious 57 Male 9/28/2009
Primary
Secondary
Rapid Eye Movements Sleep Abnormal Other Serious 10/7/2009 Physician Australia
Primary
Secondary
Parkinsonism Other Serious 53 Male 10/8/2009 Other Health Professional Australia
Primary
Secondary
Parkinsonism Other Serious 53 Male 10/13/2009 Physician Australia
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 10/7/2009
Primary
Secondary
Parkinson's Disease Other Serious 53 10/14/2009 Physician Australia
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 10/19/2009 Other Health Professional Canada
Primary
Secondary
Parkinsonism Other Serious 53 Male 10/20/2009 Other Health Professional United States
Primary
Secondary
Rapid Eye Movements Sleep Abnormal Other Serious 53 Male 10/16/2009 Physician Australia
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 10/22/2009 Physician United States
Primary
Secondary
Parkinsonism Other Serious 53 Male 10/28/2009 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 11/24/2009 Other Health Professional United States
Primary
Secondary
Nephrolithiasis Other Serious 4/1/2009 40 Male 1/7/2010 Other Health Professional Switzerland
Primary
Secondary
Nephrolithiasis Other Serious 4/1/2009 48 Male 1/11/2010 Other Health Professional Switzerland
Primary
Secondary
Retinitis Life Threatening 2/7/2000 Male 1/18/2010 Physician Japan
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 12/13/2007 44 Male 1/21/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 2/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Treatment Failure Other Serious 2/1/2005 33 Male 2/26/2010 Other Health Professional France
Primary
Secondary
Parkinsonism Other Serious 53 Male 3/2/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 3/3/2010 Physician Canada
Primary
Secondary
Visual Impairment Life Threatening 3/16/1998 Male 3/5/2010 Japan
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 3/8/2010 Physician Canada
Primary
Secondary
Treatment Failure Other Serious 2/1/2005 33 Male 3/4/2010 Other Health Professional France
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 3/11/2010 Physician Canada
Primary
Secondary
Visual Impairment Life Threatening 3/16/1998 Male 3/15/2010 Japan
Primary
Secondary
Concomitant
Treatment Failure Other Serious 2/1/2005 33 Male 3/8/2010 Other Health Professional
Primary
Secondary
Osteonecrosis Hospitalization 33 Male 3/26/2010 Other Health Professional Cote D'ivoire
Primary
Secondary
Virologic Failure Other Serious 33 Male 150 lb 3/26/2010 Other Health Professional Cote D'ivoire
Primary
Secondary
Virologic Failure Hospitalization Male 3/26/2010 Physician Brazil
Primary
Secondary
Osteonecrosis Hospitalization 33 Male 150 lb 3/31/2010 Other Health Professional Cote D'ivoire
Primary
Secondary
Osteonecrosis Hospitalization 33 Male 150 lb 3/31/2010 Other Health Professional Cote D'ivoire
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 4/1/2010 Physician Canada
Primary
Secondary
Virologic Failure Other Serious 49 Male 4/2/2010 Consumer United States
Primary
Secondary
Virologic Failure Other Serious 6/1/2007 44 Male 4/14/2010 Physician United States
Primary
Secondary
Virologic Failure Hospitalization Male 4/16/2010 Physician United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 4/28/2010 Physician Canada
Primary
Secondary
Osteonecrosis Hospitalization 33 Male 150 lb 4/29/2010 Other Health Professional Cote D'ivoire
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 5/11/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/12/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/13/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/14/2010 Other Health Professional United States
Primary
Secondary
Rash Other Serious 5/1/2005 34 Female 5/17/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 5/17/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/21/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/24/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/28/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/28/2010 Physician United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 6/3/2010 United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 6/21/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Required Intervention 52 Male 6/14/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 7/7/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 7/8/2010 Physician Canada
Primary
Secondary
Plagiocephaly Congenital Anomaly 7/9/2010 Other Health Professional United States
Primary
Secondary
Vitamin B12 Deficiency Disability 1/15/2010 26 Male 7/12/2010 Physician Japan
Primary
Secondary
Plagiocephaly Other Serious 7/13/2010 United States
Primary
Secondary
Vitamin B12 Deficiency Disability 1/15/2010 26 Male 7/21/2010 Physician Japan
Primary
Secondary
Varices Oesophageal Hospitalization 57 Male 8/11/2010
Primary
Secondary
Lung Neoplasm Malignant Hospitalization 2/1/2009 51 Male 8/12/2010 Other Health Professional Poland
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 8/12/2010 Physician Canada
Primary
Secondary
Vomiting Hospitalization 43 Female 8/16/2010 Other Health Professional Italy
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 8/18/2010 Physician Canada
Primary
Secondary
Vitamin B12 Deficiency Disability 1/15/2010 26 Male 8/19/2010 Physician Japan
Primary
Secondary
Plagiocephaly Other Serious 8/20/2010 United States
Primary
Secondary
Plagiocephaly Congenital Anomaly 12/26/2005 8/20/2010 Other Health Professional United States
Primary
Secondary

Drug Data