Mabthera



Indications and Reactions:

Role Indications Reactions
Primary
Drug Use For Unknown Indication 24.1%
Rheumatoid Arthritis 15.6%
Product Used For Unknown Indication 11.9%
Diffuse Large B-cell Lymphoma 9.0%
Non-hodgkin's Lymphoma 8.6%
B-cell Lymphoma 7.4%
Chronic Lymphocytic Leukaemia 5.3%
Lymphoma 3.4%
Premedication 2.5%
Mantle Cell Lymphoma 2.4%
Systemic Lupus Erythematosus 2.1%
Prophylaxis 1.5%
Hypertension 1.2%
Burkitt's Lymphoma 0.9%
Pain 0.9%
Malignant Lymphoid Neoplasm 0.8%
Idiopathic Thrombocytopenic Purpura 0.7%
Non-hodgkin's Lymphoma Unspecified Histology Aggressive 0.6%
Osteoporosis 0.6%
Wegener's Granulomatosis 0.5%
Death 15.6%
Progressive Multifocal Leukoencephalopathy 13.1%
Pyrexia 7.4%
Thrombocytopenia 5.7%
Neutropenia 5.4%
Pneumonia 4.9%
Sepsis 4.4%
Pneumocystis Jiroveci Pneumonia 4.0%
Pulmonary Embolism 4.0%
Disease Progression 3.9%
Myocardial Infarction 3.8%
Vomiting 3.8%
Respiratory Failure 3.4%
Febrile Neutropenia 3.4%
Renal Failure 3.3%
Pulmonary Fibrosis 3.2%
Breast Cancer 3.1%
Cerebrovascular Accident 2.9%
Interstitial Lung Disease 2.4%
Urinary Tract Infection 2.4%
Secondary
Product Used For Unknown Indication 15.8%
B-cell Lymphoma 13.7%
Rheumatoid Arthritis 13.6%
Drug Use For Unknown Indication 9.1%
Diffuse Large B-cell Lymphoma 8.1%
Non-hodgkin's Lymphoma 7.3%
Chronic Lymphocytic Leukaemia 6.5%
Lymphoma 5.1%
Mantle Cell Lymphoma 3.7%
Premedication 3.5%
Systemic Lupus Erythematosus 2.6%
Prophylaxis 2.2%
Hypertension 2.0%
Pain 1.5%
Burkitt's Lymphoma 1.5%
Malignant Lymphoid Neoplasm 1.0%
Osteoporosis 0.8%
Polymyositis 0.8%
Hypothyroidism 0.6%
Depression 0.6%
Progressive Multifocal Leukoencephalopathy 17.0%
Pyrexia 10.4%
Thrombocytopenia 7.9%
Neutropenia 7.4%
Sepsis 5.0%
Vomiting 4.3%
Lung Adenocarcinoma 4.1%
Death 3.9%
Febrile Neutropenia 3.9%
Myelodysplastic Syndrome 3.7%
Weight Increased 3.7%
Respiratory Failure 3.5%
Pneumonia 3.4%
Weight Decreased 3.3%
Pancytopenia 3.2%
Interstitial Lung Disease 3.1%
White Blood Cell Count Decreased 3.1%
Acute Myeloid Leukaemia 3.0%
Hepatitis B 2.9%
Polyneuropathy 2.9%
Concomitant
Rheumatoid Arthritis 18.2%
Drug Use For Unknown Indication 16.6%
Product Used For Unknown Indication 13.1%
Non-hodgkin's Lymphoma 11.7%
B-cell Lymphoma 5.2%
Chemotherapy 4.1%
Lymphoma 4.0%
Prophylaxis 3.3%
Diffuse Large B-cell Lymphoma 3.0%
Hepatitis C 2.7%
Osteoporosis 2.7%
Premedication 2.1%
Prophylaxis Of Nausea And Vomiting 2.1%
Chronic Lymphocytic Leukaemia 1.7%
Hypertension 1.7%
Bone Marrow Conditioning Regimen 1.7%
Vitamin Supplementation 1.7%
Diabetes Mellitus 1.4%
Immunosuppression 1.4%
Mantle Cell Lymphoma 1.4%
Sepsis 13.0%
Renal Failure 7.5%
Neutropenia 6.8%
Pancytopenia 6.8%
Thrombocytopenia 6.8%
Febrile Neutropenia 6.2%
Therapeutic Response Decreased 5.6%
Respiratory Failure 5.0%
Leukopenia 4.3%
Renal Failure Acute 4.3%
Weight Decreased 4.3%
Aplasia Pure Red Cell 3.7%
Drug Ineffective 3.7%
Myelodysplastic Syndrome 3.1%
Off Label Use 3.1%
Optic Neuropathy 3.1%
Polyneuropathy 3.1%
Pyrexia 3.1%
Septic Shock 3.1%
Wound 3.1%
Interacting
Rheumatoid Arthritis 34.0%
Drug Use For Unknown Indication 14.6%
Product Used For Unknown Indication 10.7%
Diffuse Large B-cell Lymphoma 6.8%
B-cell Lymphoma 5.8%
Chronic Lymphocytic Leukaemia 5.8%
Non-hodgkin's Lymphoma 5.8%
Pneumonia Bacterial 3.9%
Premedication 2.9%
Castleman's Disease 1.9%
Prophylaxis 1.9%
Chemotherapy 1.0%
Hypercholesterolaemia 1.0%
Hypertension 1.0%
Osteoporosis 1.0%
Parkinson's Disease 1.0%
Prophylaxis Of Nausea And Vomiting 1.0%
Drug Interaction 23.8%
Gastrointestinal Perforation 19.0%
Hepatitis Fulminant 9.5%
Neutropenia 9.5%
Thrombocytopenia 9.5%
Iiird Nerve Paralysis 4.8%
Leukopenia 4.8%
Malaise 4.8%
Pneumonitis 4.8%
Urticaria 4.8%
Venous Thrombosis 4.8%