Fludarabine Phosphate combined with Mabthera

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Treatment Related Secondary Malignancy Life Threatening 7/2/2005 59 Male 139 lb 2/16/2006 Consumer United States
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Life Threatening 7/2/2005 59 Male 139 lb 3/8/2006 Consumer Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/19/2005 74 Female 123 lb 8/22/2006 Physician Belgium
Primary
Secondary
Concomitant
Rash Erythematous Hospitalization 3/2/2006 64 Male 11/15/2006 Consumer France
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 52 Female 4/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Diplopia Hospitalization 5/15/2006 73 Male 5/17/2007 Consumer United States
Primary
Secondary
Pulmonary Oedema Other Serious Male 5/21/2007 Physician Australia
Primary
Concomitant
Visual Acuity Reduced Other Serious 50 Male 6/1/2007 Physician United Kingdom
Primary
Concomitant
Pulmonary Oedema Hospitalization 4/18/2007 Male 6/5/2007 Physician Australia
Primary
Concomitant
Neutropenia Hospitalization 4/26/2007 72 Male 137 lb 6/7/2007 Consumer France
Primary
Secondary
Concomitant
Rash Hospitalization 7/17/2005 Male 179 lb 6/19/2007 Physician France
Primary
Concomitant
Visual Acuity Reduced Other Serious 50 Male 6/22/2007 Physician United Kingdom
Primary
Concomitant
Chronic Myeloid Leukaemia Other Serious 60 Male 7/11/2007 Physician France
Primary
Concomitant
Sepsis Death 1/1/2006 7/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Death 1/1/2006 Female 7/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Life Threatening 5/24/2006 Male 192 lb 11/6/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 62 Female 11/21/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 62 Female 11/30/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 62 Female 1/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Death 60 Female 1/8/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 10/5/2006 Female 121 lb 1/28/2008 Physician France
Primary
Concomitant
Febrile Neutropenia Hospitalization 2/13/2008 Other Health Professional Australia
Primary
Secondary
Diabetes Mellitus Other Serious 69 Female 4/25/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Moniliasis Hospitalization 61 Male 4/25/2008 Physician United Kingdom
Primary
Secondary
Respiratory Moniliasis Death 55 Female 4/25/2008 Physician United Kingdom
Primary
Secondary
Mycobacterial Infection Hospitalization Female 99 lb 4/29/2008 Physician France
Primary
Secondary
Cardiac Arrest Other Serious 4/5/2008 57 Male 203 lb 5/16/2008 Physician Czech Republic
Primary
Secondary
Concomitant
Thrombosis Other Serious 6/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Gastric Ulcer Other Serious 6/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Anal Fistula Other Serious 6/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Life Threatening 2/2/2008 65 Female 6/11/2008 Physician United Kingdom
Primary
Secondary
Gouty Arthritis Disability 5/21/2008 Male 6/16/2008 Physician United Kingdom
Primary
Concomitant
Gouty Arthritis Disability 5/21/2008 Male 6/23/2008 Physician United Kingdom
Primary
Concomitant
Lung Disorder Other Serious 3/11/2008 Male 6/24/2008 Consumer United Kingdom
Primary
Concomitant
Gouty Arthritis Disability 5/21/2008 Male 7/7/2008 Physician United Kingdom
Primary
Concomitant
Pyrexia Other Serious Female 165 lb 7/7/2008 Physician United Kingdom
Primary
Concomitant
Pneumonia Other Serious 5/1/2008 Male 7/15/2008 Physician Switzerland
Primary
Concomitant
Thrombosis Other Serious 7/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/1/2007 44 Male 8/6/2008 Physician United Kingdom
Primary
Secondary
Encephalitis Cytomegalovirus Life Threatening 6/1/2004 58 Female 9/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 4/1/2000 64 Male 10/10/2008 Physician Australia
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 3/29/2007 Male 11/7/2008 Consumer United Kingdom
Primary
Concomitant
Acute Myeloid Leukaemia Other Serious 75 Male 11/7/2008 Italy
Primary
Secondary
Gastrointestinal Inflammation Other Serious 1/1/2007 Male 11/19/2008 Consumer United Kingdom
Primary
Concomitant
Nervous System Disorder Other Serious 11/10/2008 59 Male 11/25/2008 Physician United Kingdom
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 3/1/2007 Female 11/26/2008 Other Health Professional Germany
Primary
Concomitant
Chronic Lymphocytic Leukaemia Transformation Other Serious 11/26/2008 Consumer United Kingdom
Primary
Secondary
Chronic Lymphocytic Leukaemia Transformation Other Serious 11/26/2008 Consumer United Kingdom
Primary
Secondary
Guillain-barre Syndrome Hospitalization 10/25/2008 Male 12/4/2008 Physician United Kingdom
Primary
Concomitant
No Therapeutic Response Death 77 Female 12/8/2008 Other Health Professional United Kingdom
Primary
Secondary
Disease Progression Death 67 Male 12/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Disease Progression Death 77 Female 12/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Cystitis Haemorrhagic Other Serious 11/1/2008 Female 12/17/2008 Physician United Kingdom
Primary
Concomitant
Lung Disorder Other Serious 1/1/2006 81 Female 123 lb 12/18/2008 Other Health Professional France
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious 6/1/2008 Female 12/19/2008 Pharmacist United Kingdom
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 10/1/2008 Female 12/19/2008 Pharmacist United Kingdom
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 6/1/2008 Female 12/24/2008 Physician Germany
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 10/8/2008 Male 12/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 11/1/2008 Female 12/31/2008 Physician United Kingdom
Primary
Concomitant
Bone Marrow Failure Life Threatening 11/1/2008 64 Male 2/14/2009 Physician United Kingdom
Primary
Concomitant
Leukopenia Life Threatening 1/1/2007 26 Female 2/17/2009 Other Health Professional Spain
Primary
Interacting
Bone Marrow Failure Hospitalization Male 2/17/2009 Physician United Kingdom
Primary
Secondary
Muscular Weakness Other Serious 50 2/24/2009 Consumer United Kingdom
Primary
Concomitant
Neutropenia Hospitalization 1/1/2009 67 Female 2/25/2009 Other Health Professional Italy
Primary
Concomitant
Ventricular Fibrillation Life Threatening 3/4/2009 68 Male 168 lb 3/23/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 2/1/2008 Male 3/25/2009 Physician United Kingdom
Primary
Concomitant
Febrile Infection Hospitalization 1/1/2009 Male 3/26/2009 Consumer United Kingdom
Primary
Concomitant
Troponin T Increased Other Serious 4/18/2007 Male 3/31/2009 Physician Australia
Primary
Concomitant
Neutropenia Hospitalization 1/28/2009 67 Female 4/3/2009 Other Health Professional Italy
Primary
Concomitant
Febrile Neutropenia Other Serious 4/14/2009 Consumer United Kingdom
Primary
Secondary
Hepatitis B Other Serious 4/24/2009 Physician Italy
Primary
Secondary
Candida Pneumonia Other Serious 4/24/2009 Physician Italy
Primary
Concomitant
Febrile Neutropenia Other Serious 4/27/2009 Consumer United Kingdom
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 3/16/2009 Female 5/1/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 5/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 5/14/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 3/16/2009 Female 5/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lung Disorder Other Serious 1/1/2006 81 Female 123 lb 5/15/2009 Other Health Professional France
Primary
Secondary
Sudden Cardiac Death Other Serious 5/19/2009 Consumer United Kingdom
Primary
Secondary
Skin Hyperpigmentation Hospitalization 3/19/2009 Male 5/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Septic Shock Death 69 Male 5/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Sepsis Life Threatening 11/12/2008 Male 5/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 4/24/2009 57 Male 5/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sudden Cardiac Death Other Serious 5/29/2009 Consumer United Kingdom
Primary
Secondary
Pyrexia Hospitalization 6/4/2009 74 Male 170 lb 6/12/2009 Physician Australia
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 69 Male 6/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 2/5/2009 Female 119 lb 6/12/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 69 Male 6/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Pyrexia Other Serious 6/16/2009 Consumer United Kingdom
Primary
Secondary
Neutropenia Other Serious 6/18/2009 Physician Italy
Primary
Secondary
Pyrexia Other Serious 6/19/2009 Consumer United Kingdom
Primary
Secondary
Platelet Count Decreased Hospitalization 3/27/2009 Male 6/22/2009 Consumer France
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 65 Female 6/22/2009 Physician Belgium
Primary
Concomitant
Neutropenia Other Serious 6/29/2009 Physician Italy
Primary
Secondary
Staphylococcal Infection Other Serious 1/1/2008 43 Male 6/29/2009 Physician United Kingdom
Primary
Secondary
Pruritus Other Serious 6/3/2009 78 Male 7/1/2009 Consumer United Kingdom
Primary
Concomitant
Leukoencephalopathy Other Serious 66 Male 7/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 3/27/2009 Male 7/7/2009 Physician United Kingdom
Primary
Secondary
Tuberculosis Other Serious 12/1/2007 19 Male 7/7/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 8/1/2008 64 Female 7/7/2009 Consumer United Kingdom
Primary
Concomitant
Septic Shock Death 69 Male 7/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Septic Shock Other Serious 4/22/2009 66 Male 7/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Disability 6/15/2009 Female 7/30/2009 Consumer United Kingdom
Primary
Secondary
Neutropenic Sepsis Hospitalization 8/11/2009 Consumer United Kingdom
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 4/1/2009 70 Male 8/18/2009 Physician United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death 1/30/2009 Male 8/25/2009 Physician Belgium
Primary
Concomitant
Bladder Cancer Death 11/19/2008 65 Male 9/1/2009 Physician United Kingdom
Primary
Concomitant
Ulcerative Keratitis Hospitalization 5/1/2009 57 Male 9/2/2009 Other Health Professional France
Primary
Secondary
Concomitant
Neutropenia Hospitalization 3/27/2009 Male 9/2/2009 Physician United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Disability 6/15/2009 Female 9/3/2009 Consumer United Kingdom
Primary
Secondary
Neutropenia Hospitalization 4/1/2009 74 Male 9/3/2009 Other Health Professional France
Primary
Secondary
Tuberculosis Of Central Nervous System Hospitalization 6/17/2009 Female 9/9/2009 Physician Finland
Primary
Concomitant
Ulcerative Keratitis Hospitalization 5/1/2009 57 Male 10/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 7/3/2009 Male 2/17/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Breast Cancer Other Serious 2/1/2010 Female 3/22/2010 Consumer Spain
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/28/2009 64 Male 3/26/2010 Physician Italy
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 10/1/2009 Male 198 lb 3/26/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 1/6/2010 71 Male 3/29/2010 Physician United Kingdom
Primary
Concomitant
Leukopenia Other Serious 9/30/2008 53 Female 4/6/2010 Physician Germany
Primary
Concomitant
Pleural Effusion Hospitalization 1/6/2010 71 Male 4/6/2010 Physician United Kingdom
Primary
Concomitant
Serum Ferritin Increased Hospitalization 12/13/2008 62 Male 5/10/2010 Physician Finland
Primary
Secondary
Concomitant
Breast Cancer Other Serious 1/28/2010 58 Female 5/10/2010 Consumer Spain
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 3/1/2010 77 Male 5/10/2010 Physician United Kingdom
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 6/26/2010 63 Male 171 lb 7/23/2010 Physician Spain
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 7/2/2010 60 Female 10/1/2010 Consumer France
Primary
Secondary
Concomitant
Haemolysis Life Threatening 8/7/2010 63 Male 10/6/2010 Other Health Professional France
Primary
Secondary
Myelodysplastic Syndrome Hospitalization 3/10/2010 57 Male 10/18/2010 Physician Italy
Primary
Secondary
Muscle Spasms Disability 58 Female 10/29/2010 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2007 65 Male 11/16/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 7/29/2010 78 Male 168 lb 12/15/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2010 61 Female 2/18/2011 United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Hospitalization 1/1/2010 76 Female 4/8/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 1/1/2011 Male 4/14/2011 Physician United Kingdom
Primary
Concomitant
Dermatitis Exfoliative Hospitalization 4/1/2011 69 Male 7/29/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Refractory Anaemia With An Excess Of Blasts Death 6/1/2007 57 Male 8/15/2011 Other Health Professional France
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 7/2/2011 70 Female 9/8/2011 Other Health Professional France
Primary
Secondary
Concomitant
Cardiac Arrest Other Serious 9/1/2011 62 Male 9/12/2011 Consumer United Kingdom
Primary
Secondary
Cardiac Arrest Other Serious 9/1/2011 62 Male 9/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Cardiac Arrest Other Serious 9/1/2011 62 Male 9/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Cardiac Arrest Other Serious 9/1/2011 62 Male 9/20/2011 Consumer United Kingdom
Primary
Secondary
Malignant Melanoma Death 6/28/2010 80 Male 9/28/2011 Physician France
Primary
Secondary
Concomitant
Pancytopenia Death 1/14/2011 70 Female 9/29/2011 Other Health Professional France
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 7/19/2011 63 Male 201 lb 10/7/2011 Canada
Primary
Concomitant
Palpitations Other Serious 2/1/2010 52 Female 129 lb 10/12/2011 Physician Canada
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 9/6/2011 70 Male 10/14/2011 France
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 9/1/2011 73 Female 10/14/2011 France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/1/2011 37 Female 150 lb 10/14/2011 China
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 8/16/2011 64 Male 10/14/2011 Physician Denmark
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/26/2011 66 Male 159 lb 10/17/2011 Germany
Primary
Secondary
Basal Cell Carcinoma Other Serious 9/6/2011 70 Male 10/17/2011 France
Primary
Secondary
Concomitant

Drug Data