Bendamustine combined with Mabthera

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Fibrosis Other Serious Male 5/15/2007 Physician Germany
Primary
Concomitant
Pulmonary Fibrosis Other Serious 2/8/2007 Male 174 lb 5/25/2007 Physician Germany
Primary
Secondary
Venous Thrombosis Limb Other Serious 7/27/2006 Male 172 lb 5/25/2007 Physician Germany
Primary
Secondary
Dermatitis Bullous Hospitalization Male 6/14/2007 Physician Germany
Primary
Concomitant
Guillain-barre Syndrome Other Serious Male 6/19/2007 Physician Germany
Primary
Concomitant
Rash Other Serious Male 137 lb 7/6/2007 Physician Germany
Primary
Concomitant
Venous Thrombosis Limb Other Serious 7/27/2006 Male 172 lb 12/11/2007 Physician Germany
Primary
Secondary
Respiratory Distress Other Serious 5/18/2007 Female 106 lb 3/17/2008 Physician Germany
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 4/1/2008 Male 6/30/2008 Physician United Kingdom
Primary
Concomitant
Leukocytoclastic Vasculitis Other Serious 60 Female 10/1/2008 Physician United Kingdom
Primary
Secondary
Psoriatic Arthropathy Other Serious Female 10/17/2008 Physician United Kingdom
Primary
Secondary
Pulmonary Fibrosis Other Serious 3/20/2007 Male 174 lb 10/24/2008 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 3/20/2007 Male 174 lb 10/30/2008 Physician Germany
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 3/1/2007 Female 11/26/2008 Other Health Professional Germany
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 3/1/2008 Male 12/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious 6/1/2008 Female 12/24/2008 Physician Germany
Primary
Secondary
Concomitant
Fungal Infection Other Serious 65 Female 12/30/2008 Pharmacist Germany
Primary
Concomitant
Cardiomyopathy Other Serious 77 Female 1/22/2009 Physician United Kingdom
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 8/1/2008 Male 2/25/2009 Physician United Kingdom
Primary
Concomitant
Tremor Other Serious 2/20/2009 74 Male 3/12/2009 Physician United Kingdom
Primary
Secondary
Pneumonia Life Threatening 10/20/2008 69 Female 4/29/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/21/2009 Female 5/27/2009 Pharmacist Germany
Primary
Secondary
Tremor Other Serious 74 Male 6/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 3/27/2009 Male 6/10/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Leukopenia Death 6/16/2009 Other Health Professional Germany
Primary
Secondary
Neurological Symptom Other Serious 6/3/2009 Female 6/17/2009 Physician United Kingdom
Primary
Secondary
Tumour Lysis Syndrome Death 5/30/2009 Male 6/18/2009 Physician United Kingdom
Primary
Secondary
Tremor Other Serious 2/20/2009 Male 6/22/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Neurological Symptom Other Serious 6/3/2009 Female 6/23/2009 Physician United Kingdom
Primary
Secondary
Death Death 1/1/2009 70 Male 7/1/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Ileus Death 1/1/2009 70 Male 7/14/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 3/17/2009 Male 7/15/2009 Physician Germany
Primary
Secondary
Hepatitis B Hospitalization 7/2/2009 Male 7/30/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 8/6/2009 Physician Germany
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Life Threatening 8/1/2008 Male 8/25/2009 Other Health Professional Germany
Primary
Concomitant
Pulmonary Granuloma Life Threatening 5/28/2009 Male 8/27/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/15/2009 Male 9/1/2009 Physician United Kingdom
Primary
Secondary
Weight Decreased Hospitalization 7/17/2009 Male 9/2/2009 Physician United Kingdom
Primary
Secondary
Vomiting Other Serious 9/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Weight Decreased Hospitalization 7/17/2009 Male 10/1/2009 Physician Germany
Primary
Secondary
Weight Decreased Hospitalization 7/17/2009 Male 10/14/2009 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 8/22/2009 Female 10/27/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 8/1/2009 Female 11/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Rash Hospitalization 10/24/2009 84 Male 11/16/2009 Physician France
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 3/27/2009 Male 12/2/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/22/2009 Female 12/9/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Vascular Occlusion Other Serious 79 Male 12/11/2009 Physician United Kingdom
Primary
Concomitant
Urinary Incontinence Death 9/20/2009 73 Male 176 lb 12/14/2009 Physician United Kingdom
Primary
Secondary
Rash Hospitalization 10/24/2009 84 Male 12/15/2009 Physician France
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Other Serious 1/14/2010 Physician United Kingdom
Primary
Secondary
Pulmonary Embolism Death 11/24/2009 79 Male 152 lb 1/19/2010 Physician United Kingdom
Primary
Concomitant
Leukocytoclastic Vasculitis Other Serious 12/1/2009 Female 154 lb 1/26/2010 Physician United Kingdom
Primary
Concomitant
Optic Neuropathy Other Serious 1/15/2010 61 Male 2/17/2010 Physician United Kingdom
Primary
Concomitant
Optic Neuropathy Disability 1/10/2010 Male 3/15/2010 Physician United Kingdom
Primary
Concomitant
Hearing Impaired Disability 1/8/2010 80 Female 99 lb 3/18/2010 Consumer United Kingdom
Primary
Concomitant
Myopathy Toxic Other Serious 3/1/2010 Male 4/7/2010 Physician United Kingdom
Primary
Secondary
Optic Neuropathy Disability 1/10/2010 61 Male 4/23/2010 Physician France
Primary
Concomitant
Myopathy Toxic Life Threatening 3/8/2010 62 Male 190 lb 4/27/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Serum Ferritin Increased Hospitalization 12/13/2008 62 Male 5/10/2010 Physician Finland
Primary
Secondary
Concomitant
Pyrexia Hospitalization 62 Male 5/17/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Hypoxic Encephalopathy Hospitalization 3/8/2010 38 Female 5/21/2010 Physician United Kingdom
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 3/5/2010 83 Male 6/3/2010 Physician United Kingdom
Primary
Concomitant
Pancreatitis Other Serious Male 6/23/2010 Consumer United Kingdom
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 6/26/2010 63 Male 171 lb 7/23/2010 Physician Spain
Primary
Secondary
Concomitant
Immunodeficiency Other Serious 69 Female 7/28/2010 Physician United Kingdom
Primary
Secondary
Pneumonia Hospitalization 4/12/2010 82 Female 112 lb 8/3/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhinitis Allergic Other Serious Male 8/6/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 3/5/2010 83 Male 8/20/2010 Physician Finland
Primary
Secondary
Concomitant
Immunodeficiency Other Serious 12/1/2009 62 Female 132 lb 9/29/2010 Physician United Kingdom
Primary
Concomitant
Immune System Disorder Other Serious Female 122 lb 9/29/2010 Physician United Kingdom
Primary
Concomitant
Subclavian Vein Thrombosis Life Threatening 8/2/2010 54 Male 10/6/2010 Physician United Kingdom
Primary
Secondary
Hypoaesthesia Hospitalization 9/23/2010 75 Female 10/13/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hypoaesthesia Hospitalization 9/23/2010 75 Female 152 lb 10/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Urticaria Other Serious 1/1/2010 Male 10/29/2010 Consumer United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious 8/25/2010 64 Female 11/11/2010 Physician United Kingdom
Primary
Concomitant
Pseudomonas Infection Other Serious 9/1/2010 79 Male 166 lb 11/12/2010 Consumer United Kingdom
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 8/25/2010 64 Female 161 lb 11/16/2010 Physician United Kingdom
Primary
Concomitant
Interstitial Lung Disease Death 10/16/2010 63 Male 183 lb 11/24/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Lung Disorder Other Serious Female 11/24/2010 Physician United Kingdom
Primary
Secondary
Rash Other Serious 49 Male 11/29/2010 Physician United Kingdom
Primary
Secondary
Paralysis Other Serious Male 12/2/2010 Physician United Kingdom
Primary
Secondary
Lung Disorder Other Serious 9/28/2010 53 Female 165 lb 12/10/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Polyneuropathy Hospitalization 10/9/2010 68 Male 12/10/2010 Physician United Kingdom
Primary
Secondary
Rash Other Serious 11/16/2010 49 Male 12/17/2010 Physician United Kingdom
Primary
Concomitant
Atypical Mycobacterial Infection Hospitalization 68 Male 12/21/2010 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2010 79 Male 12/29/2010 Consumer United Kingdom
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 9/22/2010 76 Male 159 lb 2/1/2011 Consumer United Kingdom
Primary
Concomitant
Pleural Effusion Other Serious 1/10/2011 Male 2/2/2011 Consumer United Kingdom
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 2/1/2011 Male 3/3/2011 Physician United Kingdom
Primary
Concomitant
Paralysis Other Serious 10/1/2010 82 Female 130 lb 3/29/2011 Consumer United Kingdom
Primary
Concomitant
Glial Scar Other Serious 10/1/2010 72 Female 130 lb 4/13/2011 Physician United Kingdom
Primary
Concomitant
Back Pain Hospitalization 2/7/2011 77 Male 4/19/2011 Physician United Kingdom
Primary
Concomitant
Granuloma Hospitalization 1/1/2010 4/20/2011 Physician United Kingdom
Primary
Secondary
Sepsis Other Serious 65 Female 7/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Disability 5/1/2010 71 Female 7/27/2011 Physician United Kingdom
Primary
Concomitant
Staphylococcus Test Positive Hospitalization 6/15/2011 79 Male 8/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 3/1/2011 55 Male 8/19/2011 Consumer United Kingdom
Primary
Secondary
Fatigue Other Serious 8/25/2011 Consumer United Kingdom
Primary
Secondary
Blood Pressure Decreased Other Serious 74 Male 8/25/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Polymyalgia Rheumatica Other Serious 73 Female 9/8/2011 Consumer United Kingdom
Primary
Concomitant
Ischaemic Stroke Hospitalization 6/28/2011 68 Female 9/15/2011 Consumer United Kingdom
Primary
Secondary
Syncope Hospitalization 3/19/2011 74 Male 254 lb 9/16/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 6/15/2011 79 Male 9/22/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Anaemia Other Serious 10/3/2011 United States
Primary
Secondary
Diarrhoea Other Serious 10/10/2011 United States
Primary
Secondary
Hypoxia Death 6/12/2011 59 Male 158 lb 10/12/2011 Physician Australia
Primary
Secondary
Concomitant
Leukopenia Hospitalization 5/12/2011 76 Male 148 lb 10/13/2011 Physician Germany
Primary
Secondary
Hidradenitis Disability 9/8/2011 59 Female 143 lb 10/21/2011 Physician Germany
Primary
Secondary
Tremor Other Serious Male 10/24/2011 Physician Germany
Primary
Concomitant
Visual Impairment Other Serious 39 Male 10/31/2011 Consumer Germany
Primary
Concomitant
Deafness Neurosensory Disability 7/1/2011 65 Male 10/31/2011 Physician Spain
Primary
Secondary
Concomitant
Death Death Female 11/8/2011 Switzerland
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 1/1/2011 62 Female 143 lb 11/11/2011 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 7/19/2011 75 Male 137 lb 11/17/2011 Germany
Primary
Secondary
Chest Pain Hospitalization 8/20/2011 78 Female 11/17/2011 Physician Switzerland
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 10/18/2011 62 Female 143 lb 11/17/2011 Germany
Primary
Secondary
Blindness Hospitalization 10/2/2011 39 Male 150 lb 11/18/2011 Consumer Germany
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Other Serious 7/30/2010 73 Male 190 lb 11/18/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 10/2/2011 87 Female 11/21/2011 Switzerland
Primary
Secondary
Concomitant
Chest Pain Hospitalization 8/20/2011 78 Female 11/21/2011 Switzerland
Primary
Secondary
Concomitant
Viral Myocarditis Life Threatening 9/14/2011 72 Male 165 lb 11/22/2011 Germany
Primary
Secondary
Concomitant
Peripheral Paralysis Other Serious Male 11/24/2011 Physician Germany
Primary
Secondary
Troponin Increased Hospitalization 8/20/2011 78 Female 11/28/2011 Physician Switzerland
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 11/21/2011 75 Male 167 lb 11/29/2011 Germany
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Disability 9/8/2011 71 Male 154 lb 12/2/2011 Germany
Primary
Secondary
Concomitant
Blood Lactate Dehydrogenase Increased Hospitalization 12/7/2011 68 Female 179 lb 12/14/2011 Germany
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 10/18/2011 62 Female 143 lb 12/14/2011 Physician Germany
Primary
Secondary
Cerebral Infarction Hospitalization 8/29/2011 71 Male 154 lb 12/15/2011 Germany
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 6/20/2011 82 Male 119 lb 12/19/2011 Physician Germany
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 11/17/2011 80 Female 115 lb 12/20/2011 Physician Spain
Primary
Secondary
Concomitant
Sepsis Other Serious 12/21/2011 United States
Primary
Secondary
Dyspnoea Hospitalization 9/10/2011 73 Female 169 lb 12/21/2011 United States
Primary
Secondary
Alanine Aminotransferase Increased Other Serious 12/22/2011 United States
Primary
Secondary
Skin Disorder Other Serious 12/22/2011 Physician Sweden
Primary
Secondary
Fungal Infection Death 12/22/2011 United States
Primary
Secondary
Gamma-glutamyltransferase Increased Other Serious 12/22/2011 Physician Italy
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 10/18/2011 62 Female 143 lb 12/23/2011 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/13/2011 84 Female 117 lb 12/27/2011 Physician France
Primary
Secondary
Radius Fracture Hospitalization 12/2/2011 70 Male 196 lb 12/27/2011 Austria
Primary
Secondary
Concomitant
Hidradenitis Hospitalization 9/8/2011 59 Female 143 lb 12/27/2011 Germany
Primary
Secondary
Pseudomembranous Colitis Hospitalization 12/7/2011 68 Female 179 lb 12/29/2011 Germany
Primary
Secondary
Concomitant
Neurosensory Hypoacusis Other Serious 8/18/2011 65 Male 12/30/2011 Physician Spain
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 7/18/2011 73 Female 165 lb 1/2/2012 Physician Germany
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 6/3/2011 68 Male 172 lb 1/4/2012 Physician Germany
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 11/17/2011 80 Female 115 lb 1/4/2012 Spain
Primary
Secondary
Concomitant
Peripheral Nerve Lesion Disability 10/31/2011 46 Male 176 lb 1/9/2012 Physician Germany
Primary
Concomitant
B-cell Lymphoma Recurrent Other Serious 1/1/2011 Female 1/10/2012 Consumer Finland
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 6/22/2011 70 Female 137 lb 1/20/2012 Austria
Primary
Secondary
Concomitant
Secondary Immunodeficiency Other Serious 1/12/2012 80 Male 187 lb 1/20/2012 Physician Germany
Primary
Secondary
Death Hospitalization 12/14/2011 57 Female 1/25/2012 United States
Primary
Secondary

Drug Data