Busulfan



Indications and Reactions:

Role Indications Reactions
Primary
Stem Cell Transplant 30.1%
Bone Marrow Conditioning Regimen 24.1%
Acute Myeloid Leukaemia 9.6%
Bone Marrow Transplant 6.2%
Prophylaxis Against Graft Versus Host Disease 6.0%
Lymphoma 4.6%
Product Used For Unknown Indication 3.9%
Prophylaxis Against Transplant Rejection 2.9%
Bone Marrow Failure 2.2%
Drug Therapy 1.5%
Myelodysplastic Syndrome 1.2%
Chronic Myeloid Leukaemia 1.0%
Gastrointestinal Toxicity 1.0%
Staphylococcal Bacteraemia 1.0%
Neuroblastoma 0.9%
Thalassaemia Beta 0.9%
Allogenic Bone Marrow Transplantation Therapy 0.7%
Immunosuppressant Drug Therapy 0.7%
Multiple Myeloma 0.7%
Myelofibrosis 0.7%
Toxicity To Various Agents 10.9%
Venoocclusive Disease 7.8%
Primary Hypogonadism 7.0%
Venoocclusive Liver Disease 7.0%
Blood Follicle Stimulating Hormone Increased 6.2%
Acute Graft Versus Host Disease 5.4%
Graft Versus Host Disease 5.4%
Mucosal Inflammation 5.4%
Weight Increased 5.4%
Stem Cell Transplant 4.7%
Thrombocytopenia 4.7%
Neutropenia 3.9%
Respiratory Failure 3.9%
Septic Shock 3.9%
Chronic Graft Versus Host Disease 3.1%
Cytomegalovirus Infection 3.1%
Hepatotoxicity 3.1%
Inappropriate Antidiuretic Hormone Secretion 3.1%
Ovarian Atrophy 3.1%
Ovarian Failure 3.1%
Secondary
Prophylaxis Against Graft Versus Host Disease 15.5%
Product Used For Unknown Indication 13.3%
Stem Cell Transplant 13.0%
Bone Marrow Conditioning Regimen 11.9%
Acute Myeloid Leukaemia 8.3%
Acute Lymphocytic Leukaemia 5.2%
Prophylaxis 4.8%
Myelodysplastic Syndrome 4.6%
Infection Prophylaxis 3.6%
Haematological Malignancy 3.6%
Chromosome Analysis Abnormal 2.3%
Graft Versus Host Disease 2.0%
Antifungal Prophylaxis 1.9%
Bone Marrow Transplant 1.8%
Cord Blood Transplant Therapy 1.6%
Immunosuppression 1.5%
Drug Use For Unknown Indication 1.4%
Surgical Preconditioning 1.3%
Premedication 1.2%
Allogenic Bone Marrow Transplantation Therapy 1.2%
Venoocclusive Liver Disease 15.0%
Graft Versus Host Disease 9.3%
Infection 8.3%
Venoocclusive Disease 8.2%
Acute Graft Versus Host Disease 8.0%
Chronic Graft Versus Host Disease 5.7%
Sepsis 4.7%
Respiratory Failure 4.6%
Myelodysplastic Syndrome 3.8%
Neoplasm Malignant 3.8%
Death 3.6%
Pyrexia 3.6%
Vomiting 3.3%
Pneumonia 3.1%
Thrombocytopenia 2.8%
Mucosal Inflammation 2.6%
Progressive Multifocal Leukoencephalopathy 2.6%
Multi-organ Failure 2.4%
Transplant Rejection 2.4%
Septic Shock 2.3%
Concomitant
Prophylaxis Against Graft Versus Host Disease 17.9%
Bone Marrow Conditioning Regimen 16.5%
Product Used For Unknown Indication 14.1%
Infection Prophylaxis 9.1%
Prophylaxis 7.9%
Stem Cell Transplant 6.1%
Premedication 3.5%
Acute Myeloid Leukaemia 3.5%
Graft Versus Host Disease 3.1%
Cord Blood Transplant Therapy 3.1%
Antifungal Prophylaxis 2.5%
Bone Marrow Transplant 2.1%
Acute Lymphocytic Leukaemia 2.0%
Drug Use For Unknown Indication 1.9%
Antibiotic Prophylaxis 1.3%
Immunosuppression 1.3%
Antiviral Prophylaxis 1.1%
Allogenic Bone Marrow Transplantation Therapy 1.0%
Acute Graft Versus Host Disease 0.9%
Prophylaxis Of Nausea And Vomiting 0.9%
Drug Ineffective 10.1%
Acute Graft Versus Host Disease 9.4%
Pyrexia 8.4%
Sepsis 7.7%
Thrombotic Microangiopathy 7.2%
Death 6.7%
Graft Versus Host Disease 6.4%
Venoocclusive Disease 4.4%
Cytomegalovirus Infection 4.2%
Cystitis Haemorrhagic 3.7%
Vomiting 3.7%
Weight Increased 3.7%
Chronic Graft Versus Host Disease 3.5%
Febrile Neutropenia 3.2%
Post Transplant Lymphoproliferative Disorder 3.2%
Respiratory Failure 3.2%
Interstitial Lung Disease 3.0%
Thrombocytopenia 3.0%
Transplant Rejection 3.0%
Staphylococcal Infection 2.5%
Interacting
Stem Cell Transplant 38.5%
Prophylaxis Against Graft Versus Host Disease 19.2%
Clostridial Infection 11.5%
Convulsion Prophylaxis 7.7%
Graft Versus Host Disease 7.7%
Antifungal Prophylaxis 3.8%
Convulsion 3.8%
Iron Overload 3.8%
Prophylaxis 3.8%
Drug Interaction 100.0%