Busulfan combined with Cytarabine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Transplant Rejection Other Serious 1 Male 3/15/2006 Japan
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 6/27/2005 1 Male 19 lb 3/17/2006 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 20 Male 4/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 6/28/2006 Female 160 lb 6/30/2006 United States
Primary
Secondary
Pulmonary Haemorrhage Hospitalization 11/27/2006 Female 154 lb 1/22/2007 United States
Primary
Secondary
Stem Cell Transplant Death 7/4/2007 Female 128 lb 8/2/2007 United States
Primary
Secondary
Somnolence Hospitalization 8/1/2007 8 Male 88 lb 9/11/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Somnolence Other Serious 8/1/2007 8 Male 88 lb 10/12/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Somnolence Other Serious 1/1/2007 8 Male 88 lb 10/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Other Serious 8/1/2007 8 Male 88 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 53 Male 12/6/2007 Other Health Professional Portugal
Primary
Secondary
Renal Tubular Necrosis Other Serious 53 Male 12/12/2007 Other Health Professional Portugal
Primary
Secondary
Drug Toxicity Death 2/22/2008 France
Primary
Secondary
Concomitant
Complications Of Bone Marrow Transplant Death 2/22/2008 Germany
Primary
Secondary
Concomitant
Complications Of Bone Marrow Transplant Death 2/22/2008 Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/5/2008 Male 213 lb 2/13/2008 United States
Primary
Secondary
Concomitant
Complications Of Bone Marrow Transplant Death 2/26/2008 Germany
Primary
Secondary
Concomitant
Complications Of Bone Marrow Transplant Death 2/26/2008 Germany
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious Male 6/14/2008 Consumer United States
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious Male 6/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 47 Male 6/19/2008 United States
Primary
Secondary
Post Procedural Complication Other Serious 57 Male 6/19/2008 United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 57 Male 6/23/2008 Other Health Professional United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 47 Male 6/24/2008 United States
Primary
Secondary
Stem Cell Transplant Death 57 Male 6/24/2008 United States
Primary
Secondary
Stem Cell Transplant Other Serious 57 Male 6/25/2008 Other Health Professional United States
Primary
Secondary
Tuberculosis Other Serious 31 Female 7/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Guillain-barre Syndrome Other Serious 1/1/2006 61 Male 7/23/2008 Other Health Professional United States
Primary
Secondary
Therapeutic Agent Toxicity Other Serious 8/6/2008 China
Primary
Concomitant
Tremor Other Serious 8/6/2008 China
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 8/6/2008 China
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 8/6/2008 China
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 8/6/2008 China
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 8/6/2008 China
Primary
Concomitant
Therapeutic Agent Toxicity Death 8/6/2008 China
Primary
Concomitant
Vomiting Other Serious 31 Female 8/7/2008 United Kingdom
Primary
Secondary
Vomiting Other Serious 31 Female 8/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Hospitalization 31 Female 8/13/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 31 Female 8/13/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 31 Female 8/21/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 31 Female 8/22/2008 United Kingdom
Primary
Secondary
Vomiting Hospitalization 31 Female 8/28/2008 United Kingdom
Primary
Secondary
Concomitant
Complications Of Bone Marrow Transplant Death 8/29/2008 Germany
Primary
Secondary
Concomitant
Complications Of Bone Marrow Transplant Death 8/29/2008 Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 31 Female 9/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Hospitalization 31 Female 10/14/2008 Consumer United States
Primary
Secondary
Concomitant
Drug Toxicity Death 11/17/2008 France
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 3/1/2006 13 Female 11/24/2008 Other Health Professional Japan
Primary
Concomitant
Toxic Encephalopathy Other Serious 3/1/2006 13 Female 11/26/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 3/1/2006 13 Female 11/26/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/20/2008 Male 140 lb 2/3/2009 United States
Primary
Secondary
Concomitant
Nausea Life Threatening 9/28/2008 59 Female 123 lb 3/16/2009 Physician Japan
Primary
Secondary
Concomitant
Salivary Gland Cancer Other Serious 5 Male 3/20/2009 Other Health Professional Korea, Republic Of
Primary
Secondary
Viral Haemorrhagic Cystitis Other Serious 6/27/2008 44 Male 148 lb 3/20/2009 Physician Japan
Primary
Concomitant
Skin Lesion Other Serious 5 Male 3/20/2009 Consumer Korea, Republic Of
Primary
Secondary
Mucoepidermoid Carcinoma Other Serious 5 Male 3/24/2009 Consumer Japan
Primary
Secondary
Skin Lesion Other Serious 5 Male 3/25/2009 Consumer Korea, Republic Of
Primary
Secondary
Sepsis Life Threatening 6/27/2008 36 Female 97 lb 4/9/2009 Physician Japan
Primary
Concomitant
Febrile Neutropenia Other Serious 4/14/2009 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Other Serious 4/27/2009 Consumer United Kingdom
Primary
Secondary
Pericardial Effusion Hospitalization 4/24/2009 Female 262 lb 4/29/2009 United States
Primary
Secondary
Vomiting Other Serious 9 5/8/2009 Other Health Professional Japan
Primary
Secondary
Sepsis Other Serious 1/30/2009 40 Male 110 lb 5/14/2009 Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 54 Male 5/18/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Prinzmetal Angina Other Serious 56 Female 6/1/2009
Primary
Secondary
Mucoepidermoid Carcinoma Other Serious 5 Male 6/24/2009
Primary
Secondary
Mucoepidermoid Carcinoma Other Serious Male 6/26/2009 Korea, Republic Of
Primary
Secondary
Salivary Gland Cancer Other Serious 1/1/2009 5 Male 6/30/2009 Other Health Professional Korea, Democratic People's Republic Of
Primary
Secondary
Mucoepidermoid Carcinoma Other Serious Male 7/6/2009 Other Health Professional Korea, Republic Of
Primary
Secondary
Stomatitis Life Threatening 9/23/2008 59 Female 123 lb 8/6/2009 Physician Japan
Primary
Secondary
Concomitant
Viral Haemorrhagic Cystitis Other Serious 6/27/2008 44 Male 148 lb 8/17/2009 Physician Japan
Primary
Concomitant
Sepsis Other Serious 1/30/2009 40 Male 110 lb 8/27/2009 Japan
Primary
Concomitant
Sepsis Life Threatening 1/30/2009 40 Male 110 lb 9/9/2009 Japan
Primary
Concomitant
Sepsis Other Serious 1/30/2009 40 Male 110 lb 9/11/2009 Japan
Primary
Concomitant
Stomatitis Life Threatening 9/28/2008 59 Female 123 lb 9/15/2009 Physician Japan
Primary
Secondary
Concomitant
Electrolyte Imbalance Hospitalization 3/15/2008 Female 10/2/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Electrolyte Imbalance Hospitalization 3/15/2008 Female 11/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 5/27/2009 65 Male 12/29/2009 Physician Japan
Primary
Concomitant
Interacting
Interstitial Lung Disease Hospitalization 11/30/2009 Female 191 lb 1/8/2010 United States
Primary
Secondary
Sepsis Other Serious 1/1/2009 65 Male 2/1/2010 Other Health Professional Japan
Primary
Concomitant
Interacting
Vomiting Hospitalization 31 Female 2/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 31 Female 2/26/2010 United Kingdom
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 4/1/2010 49 Female 7/9/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Vomiting Other Serious 4/23/2010 49 Female 119 lb 7/9/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 4/1/2010 49 Female 7/15/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 4/1/2010 49 Female 119 lb 7/27/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 4/1/2010 49 Female 119 lb 7/27/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Septic Shock Other Serious 56 Female 8/4/2010 Other Health Professional France
Primary
Secondary
Concomitant
Stridor Hospitalization 7/29/2010 46 Male 206 lb 7/30/2010 United States
Primary
Secondary
Vomiting Other Serious 4/23/2010 49 Female 119 lb 8/6/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Septic Shock Other Serious 56 Female 8/10/2010 Other Health Professional France
Primary
Secondary
Concomitant
Sepsis Other Serious 28 Female 8/13/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 1/23/2010 66 Male 130 lb 8/13/2010 Consumer Japan
Primary
Concomitant
Herpes Zoster Other Serious 10/30/2009 31 Male 128 lb 8/16/2010 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 1/23/2010 67 Male 130 lb 8/19/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 1/23/2010 67 Male 130 lb 8/24/2010 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 10/30/2009 31 Male 8/24/2010 Physician Japan
Primary
Secondary
Concomitant
Transplant Failure Other Serious 7 Male 8/27/2010 Other Health Professional Jordan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 21 Female 9/16/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Nervous System Disorder Disability 8/1/1999 39 Female 9/21/2010 Physician France
Primary
Secondary
Herpes Zoster Other Serious 10/30/2009 31 Male 128 lb 10/20/2010 Physician Japan
Primary
Concomitant
Encephalopathy Other Serious 4/10/2010 35 Male 139 lb 10/20/2010 Physician Japan
Primary
Concomitant
Stenotrophomonas Infection Hospitalization 5/17/2010 59 Male 126 lb 10/21/2010 Physician Japan
Primary
Concomitant
Stenotrophomonas Infection Hospitalization 5/17/2010 59 Male 126 lb 10/27/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 21 Female 11/5/2010 Other Health Professional Germany
Primary
Concomitant
Lymphoma Hospitalization 5/9/2010 57 Male 172 lb 11/5/2010 Physician United Kingdom
Primary
Secondary
Encephalitis Other Serious 9/1/2010 38 Female 11/9/2010 Other Health Professional France
Primary
Concomitant
Thyroid Disorder Other Serious 7/17/2009 28 Male 110 lb 11/23/2010 Physician Japan
Primary
Concomitant
Cytomegalovirus Infection Other Serious 7/17/2009 28 Male 110 lb 11/24/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia 9/24/2010 62 Female 136 lb 11/16/2010 United States
Primary
Secondary
Nervous System Disorder Disability 1/1/1999 39 Female 12/2/2010 Physician France
Primary
Secondary
Lymphoma Hospitalization 5/9/2010 57 Male 172 lb 12/9/2010 Physician United Kingdom
Primary
Secondary
Myelodysplastic Syndrome 11/10/2010 53 Female 159 lb 12/2/2010 United States
Primary
Secondary
Transaminases Increased Other Serious 8/23/2010 20 Female 104 lb 12/30/2010 Physician France
Primary
Concomitant
Diarrhoea Other Serious 1/3/2011 Physician Italy
Primary
Secondary
Concomitant
Bk Virus Infection Death 20 Female 1/24/2011 Other Health Professional Singapore
Primary
Secondary
Pneumonia Death 68 Female 1/27/2011 Physician Germany
Primary
Secondary
Concomitant
Systemic Candida Death 20 Female 1/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Encephalitis Hospitalization 9/6/2010 38 Female 2/3/2011 Other Health Professional France
Primary
Secondary
Concomitant
Encephalitis Other Serious 9/1/2010 38 Female 2/8/2011 Other Health Professional France
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 20 Female 2/8/2011 Other Health Professional Singapore
Primary
Secondary
Concomitant
Posterior Reversible Encephalopathy Syndrome Hospitalization 20 Female 2/8/2011 Other Health Professional Singapore
Primary
Secondary
Concomitant
Central Nervous System Lymphoma Hospitalization 20 Female 2/8/2011 Other Health Professional Singapore
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 20 Female 2/8/2011 Other Health Professional Singapore
Primary
Secondary
Concomitant
Sepsis Death 20 Female 2/8/2011 Other Health Professional Singapore
Primary
Secondary
Hypoxia Death 2 Male 2/11/2011 Other Health Professional United States
Primary
Concomitant
Haematuria Other Serious 20 Female 2/11/2011 Other Health Professional Singapore
Primary
Secondary
Stevens-johnson Syndrome Other Serious 20 Female 2/16/2011 Other Health Professional Singapore
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 21 Female 3/1/2011 Other Health Professional Germany
Primary
Concomitant
Sepsis Hospitalization 20 Female 2/15/2011
Primary
Secondary
Pyrexia Other Serious 3/5/2011 Physician Italy
Primary
Secondary
Concomitant
Endothelial Dysfunction Other Serious 2 Male 2/25/2011 Physician United States
Primary
Secondary
Concomitant
Pulmonary Granuloma Other Serious 9/8/2009 64 Male 217 lb 3/17/2011 Physician United States
Primary
Concomitant
Stem Cell Transplant Death 9/8/2009 64 Male 217 lb 3/17/2011 Physician United States
Primary
Concomitant
Bronchiectasis Hospitalization 35 Male 3/30/2011 Other Health Professional Japan
Primary
Concomitant
Microangiopathy Death 2 Male 4/1/2011 Other Health Professional United States
Primary
Concomitant
Venoocclusive Liver Disease Death 6/16/2010 30 Female 101 lb 4/15/2011 Physician China
Primary
Secondary
Concomitant
Death Other Serious 1 Male 4/22/2011 Other Health Professional Iran (Islamic Republic Of)
Primary
Concomitant
Disease Progression Hospitalization 9/1/2010 38 Female 5/9/2011 Other Health Professional France
Primary
Concomitant
Acute Myeloid Leukaemia Hospitalization 9/6/2010 38 Female 5/10/2011 Other Health Professional France
Primary
Secondary
Concomitant
Fungal Infection Death 42 Male 5/18/2011 Physician China
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 24 Male 5/18/2011 Physician China
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 30 Male 5/19/2011 Physician China
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 20 Male 5/19/2011 Physician China
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 24 Male 5/19/2011 Physician China
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 31 Female 5/19/2011 Physician China
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 44 Female 5/19/2011 Physician China
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 55 Male 5/25/2011 Physician China
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 8/23/2010 20 Female 104 lb 5/27/2011 Physician France
Primary
Concomitant
Escherichia Infection Other Serious 54 Female 6/15/2011 Other Health Professional Japan
Primary
Secondary
Concomitant

Drug Data