Busulfan combined with Etoposide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Other Serious 1/16/2006 Female 130 lb 1/17/2006 United States
Primary
Secondary
Blood Bilirubin Increased Other Serious 1/7/2005 3 Female 5/24/2006 Spain
Primary
Concomitant
Respiratory Disorder Death 2/26/2004 6 Male 6/16/2006 Consumer Japan
Primary
Secondary
Myelitis Hospitalization 1/1/2004 25 Male 12/15/2006 Other Health Professional United States
Primary
Secondary
Malignant Neoplasm Progression Other Serious 4 Female 1/19/2007 Other Health Professional Belgium
Primary
Secondary
Tenderness Other Serious 4 Female 1/26/2007
Primary
Secondary
Stem Cell Transplant Death 4 Female 1/26/2007 Belgium
Primary
Secondary
Weight Decreased Other Serious 12/1/2004 49 Male 2/10/2007 Japan
Primary
Concomitant
Stem Cell Transplant Death 4 Female 2/7/2007 Belgium
Primary
Secondary
Malignant Neoplasm Progression Death 4 Female 2/14/2007 Belgium
Primary
Secondary
Malignant Neoplasm Progression Death 4 Female 2/26/2007 Belgium
Primary
Secondary
Malignant Neoplasm Progression Death 4 Female 3/9/2007 Belgium
Primary
Secondary
No Adverse Effect 4 Female 5/25/2007 Belgium
Primary
Secondary
Pleural Effusion Other Serious 46 Male 6/24/2007 Japan
Primary
Concomitant
Pleural Effusion Other Serious 46 Male 7/6/2007 Japan
Primary
Concomitant
Secondary Immunodeficiency Life Threatening 5/4/2007 10 Male 93 lb 7/2/2007 Denmark
Primary
Concomitant
Stem Cell Transplant Death 7/4/2007 Female 128 lb 8/2/2007 United States
Primary
Secondary
Mucosal Exfoliation Other Serious 27 Male 8/28/2007 Israel
Primary
Secondary
Paralysis Life Threatening 5/4/2007 10 Male 93 lb 8/29/2007 Denmark
Primary
Concomitant
Renal Tubular Necrosis Other Serious 53 Male 12/6/2007 Other Health Professional Portugal
Primary
Secondary
Renal Tubular Necrosis Other Serious 53 Male 12/12/2007 Other Health Professional Portugal
Primary
Secondary
Venoocclusive Liver Disease Other Serious 4 Male 2/15/2008 Japan
Primary
Secondary
Concomitant
Venoocclusive Disease Death 2/22/2008 Other Health Professional Germany
Primary
Concomitant
Pyrexia Hospitalization 2/5/2008 Male 213 lb 2/13/2008 United States
Primary
Secondary
Concomitant
Speech Rehabilitation Other Serious 1 Female 2/25/2008 Other Health Professional Japan
Primary
Concomitant
Venoocclusive Disease Death 2/29/2008 Other Health Professional Germany
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 4 Male 3/7/2008 Other Health Professional Japan
Primary
Secondary
Subcutaneous Nodule Other Serious 4 Female 4/3/2008 Japan
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 4/15/2008 Other Health Professional Germany
Primary
Concomitant
Graft Versus Host Disease Other Serious 14 Female 4/23/2008 Germany
Primary
Concomitant
Graft Versus Host Disease Other Serious 14 Female 5/5/2008 Germany
Primary
Concomitant
Stem Cell Transplant Other Serious Male 6/14/2008 Consumer United States
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious Male 6/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 47 Male 6/19/2008 United States
Primary
Secondary
Post Procedural Complication Other Serious 57 Male 6/19/2008 United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 57 Male 6/23/2008 Other Health Professional United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 47 Male 6/24/2008 United States
Primary
Secondary
Stem Cell Transplant Death 57 Male 6/24/2008 United States
Primary
Secondary
Stem Cell Transplant Other Serious 57 Male 6/25/2008 Other Health Professional United States
Primary
Secondary
Guillain-barre Syndrome Other Serious 20 Male 8/5/2008 Other Health Professional United States
Primary
Secondary
Therapeutic Agent Toxicity Other Serious 14 Female 9/26/2008 Other Health Professional Germany
Primary
Concomitant
Pancytopenia Other Serious 0 Female 10/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Alopecia 55 Male 11/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Post Procedural Complication 65 Female 11/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Alopecia 51 Male 11/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 3/1/2006 13 Female 11/24/2008 Other Health Professional Japan
Primary
Concomitant
Toxic Encephalopathy Other Serious 3/1/2006 13 Female 11/26/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 3/1/2006 13 Female 11/26/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Ineffective Other Serious Male 1/6/2009 Physician Sweden
Primary
Concomitant
Drug Ineffective Other Serious Male 1/6/2009 Physician Sweden
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 1/19/2009 United States
Primary
Secondary
Interstitial Lung Disease Other Serious 3 Male 1/26/2009 Other Health Professional Japan
Primary
Secondary
Interstitial Lung Disease Death 3 Male 2/6/2009 Consumer Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/20/2008 Male 140 lb 2/3/2009 United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 3 Male 2/16/2009 Consumer Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 3 Male 2/17/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 3 Male 2/17/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Salivary Gland Cancer Other Serious 5 Male 3/20/2009 Other Health Professional Korea, Republic Of
Primary
Secondary
Skin Lesion Other Serious 5 Male 3/20/2009 Consumer Korea, Republic Of
Primary
Secondary
Mucoepidermoid Carcinoma Other Serious 5 Male 3/24/2009 Consumer Japan
Primary
Secondary
Skin Lesion Other Serious 5 Male 3/25/2009 Consumer Korea, Republic Of
Primary
Secondary
Febrile Neutropenia Other Serious 4/14/2009 Consumer United Kingdom
Primary
Secondary
Acute Promyelocytic Leukaemia Other Serious 25 Female 4/23/2009 Other Health Professional France
Primary
Secondary
Febrile Neutropenia Other Serious 4/27/2009 Consumer United Kingdom
Primary
Secondary
Pericardial Effusion Hospitalization 4/24/2009 Female 262 lb 4/29/2009 United States
Primary
Secondary
Vomiting Other Serious 9 5/8/2009 Other Health Professional Japan
Primary
Secondary
Rhabdomyolysis Hospitalization 54 Male 5/18/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 19 Male 6/17/2009 Other Health Professional United States
Primary
Concomitant
Mucoepidermoid Carcinoma Other Serious 5 Male 6/24/2009
Primary
Secondary
Mucoepidermoid Carcinoma Other Serious Male 6/26/2009 Korea, Republic Of
Primary
Secondary
Salivary Gland Cancer Other Serious 1/1/2009 5 Male 6/30/2009 Other Health Professional Korea, Democratic People's Republic Of
Primary
Secondary
Mucoepidermoid Carcinoma Other Serious Male 7/6/2009 Other Health Professional Korea, Republic Of
Primary
Secondary
Vena Cava Thrombosis Hospitalization 7/23/2008 Female 197 lb 9/15/2009 United States
Primary
Secondary
Pyrexia Other Serious 0 Female 11/3/2009 Other Health Professional Japan
Primary
Concomitant
Venoocclusive Disease Death 0 11/11/2009 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Morphology Abnormal Death 43 Male 11/12/2009 Physician United States
Primary
Secondary
Interstitial Lung Disease Hospitalization 11/30/2009 Female 191 lb 1/8/2010 United States
Primary
Secondary
Urosepsis Hospitalization 4/2/2009 58 Male 220 lb 6/29/2010 Physician France
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 7/19/2010 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious Female 7/15/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Septic Shock Other Serious 56 Female 8/4/2010 Other Health Professional France
Primary
Secondary
Concomitant
Stridor Hospitalization 7/29/2010 46 Male 206 lb 7/30/2010 United States
Primary
Secondary
Weight Increased Other Serious 1/1/1995 57 Male 8/6/2010 United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 56 Female 8/10/2010 Other Health Professional France
Primary
Secondary
Concomitant
Treatment Failure Other Serious 13 Male 8/26/2010
Primary
Secondary
Venoocclusive Disease Other Serious 8/26/2010 Korea, Republic Of
Primary
Secondary
Concomitant
Vomiting Hospitalization 0 Female 9/14/2010 Other Health Professional Japan
Primary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 9/17/2010 United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 9/23/2010 60 Male 149 lb 10/11/2010 United States
Primary
Secondary
Thrombotic Microangiopathy Death 9/21/2009 62 Female 126 lb 11/3/2010 Physician Japan
Primary
Concomitant
Pyrexia Life Threatening Male 112 lb 11/24/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia 9/24/2010 62 Female 136 lb 11/16/2010 United States
Primary
Secondary
Pyrexia Life Threatening Male 112 lb 11/24/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 18 Female 12/27/2010 Other Health Professional Japan
Primary
Concomitant
Thrombocytopenia Other Serious 43 Male 12/12/2010 Physician United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 2/23/2010 69 Male 130 lb 12/30/2010 Physician Japan
Primary
Concomitant
Bacterial Infection Death 8/20/2009 46 Male 161 lb 1/3/2011 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Death 10/23/2009 62 Male 130 lb 1/6/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 10/23/2009 62 Male 130 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Cytomegalovirus Test Positive Death 5/1/2010 54 Female 119 lb 1/10/2011 Physician Japan
Primary
Concomitant
Infection Life Threatening 7/4/2010 73 Female 97 lb 1/10/2011 Physician Japan
Primary
Concomitant
Cystitis Haemorrhagic Hospitalization 5/17/2010 43 Female 1/10/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Death 8/6/2010 35 Female 71 lb 1/10/2011 Physician Japan
Primary
Concomitant
Infection Life Threatening 7/4/2010 73 Female 97 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Cytomegalovirus Test Positive Hospitalization 5/1/2010 54 Female 119 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Infection Life Threatening 7/4/2010 73 Female 97 lb 1/13/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 8/6/2010 35 Female 71 lb 1/14/2011 Physician Japan
Primary
Secondary
Concomitant
Bk Virus Infection Death 20 Female 1/24/2011 Other Health Professional Singapore
Primary
Secondary
Thrombotic Microangiopathy Death 9/21/2009 62 Female 126 lb 1/26/2011 Physician Japan
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 5/17/2010 43 Female 119 lb 1/26/2011 Physician Japan
Primary
Concomitant
Systemic Candida Death 20 Female 1/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Stevens-johnson Syndrome Hospitalization 20 Female 2/8/2011 Other Health Professional Singapore
Primary
Secondary
Concomitant
Posterior Reversible Encephalopathy Syndrome Hospitalization 20 Female 2/8/2011 Other Health Professional Singapore
Primary
Secondary
Concomitant
Central Nervous System Lymphoma Hospitalization 20 Female 2/8/2011 Other Health Professional Singapore
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 20 Female 2/8/2011 Other Health Professional Singapore
Primary
Secondary
Concomitant
Sepsis Death 20 Female 2/8/2011 Other Health Professional Singapore
Primary
Secondary
Hypoxia Death 2 Male 2/11/2011 Other Health Professional United States
Primary
Concomitant
Haematuria Other Serious 20 Female 2/11/2011 Other Health Professional Singapore
Primary
Secondary
Stevens-johnson Syndrome Other Serious 20 Female 2/16/2011 Other Health Professional Singapore
Primary
Secondary
Concomitant
Neutropenia Other Serious 15 Male 2/7/2011 Physician Japan
Primary
Concomitant
Neutropenia Other Serious 10 Female 2/7/2011 Physician Japan
Primary
Concomitant
Septic Shock Other Serious 1 Male 2/7/2011 Physician Japan
Primary
Concomitant
Neutropenia Other Serious 3 Female 2/7/2011 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 20 Female 2/15/2011
Primary
Secondary
Hepatosplenomegaly Death 1/27/2011 68 Male 2/15/2011 Other Health Professional United States
Primary
Concomitant
Dysuria Other Serious 2/8/2011 49 Female 2/23/2011 Physician United States
Primary
Concomitant
Intestinal Ulcer Life Threatening 12/14/2010 56 Male 2/23/2011 Physician United States
Primary
Concomitant
Cystitis Haemorrhagic Death 10/14/2010 49 Male 2/23/2011 Physician United States
Primary
Concomitant
Endothelial Dysfunction Other Serious 2 Male 2/25/2011 Physician United States
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Hospitalization 5/17/2010 43 Female 119 lb 3/10/2011 Physician Japan
Primary
Concomitant
Pneumonia Aspiration Disability 2/11/2011 72 Male 3/9/2011 Other Health Professional United States
Primary
Concomitant
Obliterative Bronchiolitis Death 55 Male 3/21/2011 Consumer Japan
Primary
Secondary
Obliterative Bronchiolitis Death 55 Male 3/22/2011 Consumer Japan
Primary
Secondary
Abdominal Distension Other Serious 10/7/2010 49 Male 3/10/2011 Other Health Professional United States
Primary
Concomitant
Bacterial Test Positive Other Serious 11/20/2010 57 Female 3/11/2011 Other Health Professional United States
Primary
Concomitant
Cystitis Haemorrhagic Hospitalization 5/17/2010 43 Female 119 lb 3/25/2011 Physician Japan
Primary
Concomitant
Hypomagnesaemia Other Serious 1/1/1995 57 Male 3/28/2011 Lawyer United States
Primary
Secondary
Concomitant
Pulmonary Granuloma Other Serious 9/8/2009 64 Male 217 lb 3/17/2011 Physician United States
Primary
Concomitant
Hypoxia Life Threatening 8/25/2010 25 Male 3/17/2011 Other Health Professional United States
Primary
Concomitant
Stem Cell Transplant Death 9/8/2009 64 Male 217 lb 3/17/2011 Physician United States
Primary
Concomitant
Microangiopathy Death 2 Male 4/1/2011 Other Health Professional United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 16 4/10/2011 Other Health Professional Japan
Primary
Secondary
Engraftment Syndrome Other Serious 4/1/2011 Physician Spain
Primary
Secondary
Concomitant
Toxicity To Various Agents Other Serious 4/1/2011 Physician Spain
Primary
Secondary
Concomitant
Engraftment Syndrome Other Serious 4/1/2011 Physician Spain
Primary
Secondary
Concomitant
Toxicity To Various Agents Other Serious 4/1/2011 Physician Spain
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 16 4/15/2011 Other Health Professional Japan
Primary
Secondary
Lymphopenia Death 10 Female 4/11/2011 Physician United States
Primary
Secondary
Concomitant
Syncope Disability 1/24/2011 72 Male 4/8/2011 Other Health Professional United States
Primary
Concomitant
Muscular Weakness Hospitalization 16 4/13/2011 Consumer Japan
Primary
Secondary
Concomitant

Drug Data