Busulfan combined with Fluconazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Other Serious 10/1/2005 59 Male 198 lb 1/24/2006 Pharmacist Spain
Primary
Concomitant
Skin Exfoliation Other Serious 31 Female 10/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/5/2008 Male 213 lb 2/13/2008 United States
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 6/30/2007 56 Female 140 lb 3/26/2008 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 5/22/2008 Japan
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 9 Female 6/13/2008 Germany
Primary
Secondary
Venoocclusive Liver Disease Other Serious 48 Male 6/20/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 9 Female 6/25/2008 Other Health Professional Germany
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 8/15/2008 Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 8/15/2008 Other Health Professional Brazil
Primary
Concomitant
Hepatitis Hospitalization Female 9/12/2008 Other Health Professional
Primary
Concomitant
Venoocclusive Disease Other Serious 9/29/2008 Korea, Republic Of
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 10/16/2008 Other Health Professional Brazil
Primary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 166 lb 11/5/2008 Other Health Professional Brazil
Primary
Concomitant
Febrile Neutropenia Other Serious 12/26/2008 15 Female 99 lb 6/5/2009 Physician Japan
Primary
Concomitant
Sudden Death Other Serious 7/6/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 7/1/2008 Female 93 lb 7/22/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 7/1/2008 Female 93 lb 8/3/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypertension Other Serious 12/16/2008 15 Female 99 lb 8/27/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 7/1/2008 Female 93 lb 2/5/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/12/2010 59 Male 132 lb 7/16/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 3/12/2010 59 Male 132 lb 7/19/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 3/12/2010 59 Male 7/21/2010 Physician Japan
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 9/16/2007 49 Male 303 lb 8/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 8/26/2010 Korea, Republic Of
Primary
Secondary
Concomitant
Toxoplasmosis Other Serious 42 Female 9/17/2010 Other Health Professional Greece
Primary
Secondary
Concomitant
Toxoplasmosis Other Serious 42 Female 9/22/2010 Other Health Professional Greece
Primary
Secondary
Concomitant
Toxoplasmosis Death 42 Female 10/7/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 5/11/2009 70 Female 86 lb 10/15/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 10/2/2010 15 Male 115 lb 10/25/2010 Physician Mexico
Primary
Concomitant
Staphylococcal Sepsis Life Threatening 1/14/2009 67 Male 99 lb 10/26/2010 Consumer Japan
Primary
Concomitant
Transplant Failure Other Serious 12/27/2008 52 Male 152 lb 10/28/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 11/8/2010 Other Health Professional China
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 8/23/2010 20 Female 104 lb 12/30/2010 Physician France
Primary
Concomitant
Interstitial Lung Disease Hospitalization 2/23/2010 69 Male 130 lb 12/30/2010 Physician Japan
Primary
Concomitant
Diarrhoea Other Serious 1/3/2011 Physician Italy
Primary
Secondary
Concomitant
Respiratory Failure Death 1/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Enterococcal Sepsis Death 5/5/2010 48 Male 137 lb 1/6/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 10/23/2009 62 Male 130 lb 1/6/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 10/23/2009 62 Male 130 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Death 5/5/2010 48 Male 137 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Death 8/6/2010 35 Female 71 lb 1/10/2011 Physician Japan
Primary
Concomitant
Staphylococcal Infection Death 4/14/2010 60 Male 110 lb 1/20/2011 Physician Japan
Primary
Concomitant
Escherichia Sepsis Death 55 Male 1/27/2011 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 42 Male 1/27/2011 Physician Germany
Primary
Secondary
Concomitant
Cytomegalovirus Infection Death 48 Female 1/27/2011 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Other Serious 68 Female 1/27/2011 Physician Germany
Primary
Secondary
Concomitant
Soft Tissue Infection Other Serious 39 Male 1/27/2011 Consumer Germany
Primary
Secondary
Concomitant
Pneumonia Other Serious 19 Male 1/27/2011 Physician Germany
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 64 Male 1/27/2011 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Other Serious 37 Male 1/27/2011 Physician Germany
Primary
Secondary
Concomitant
Organising Pneumonia Other Serious 53 Male 1/27/2011 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Death 68 Female 1/27/2011 Physician Germany
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 53 Male 1/27/2011 Physician Germany
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 64 Male 1/28/2011 Physician Germany
Primary
Secondary
Concomitant
Dehydration Other Serious 10/1/2010 47 Male 2/11/2011 Other Health Professional Canada
Primary
Concomitant
Ileus Other Serious 3/1/2011 Physician United States
Primary
Secondary
Concomitant
Hepatosplenomegaly Death 1/27/2011 68 Male 2/15/2011 Other Health Professional United States
Primary
Concomitant
Pyrexia Other Serious 3/5/2011 Physician Italy
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Death 10/14/2010 49 Male 2/23/2011 Physician United States
Primary
Concomitant
Abdominal Distension Other Serious 10/7/2010 49 Male 3/10/2011 Other Health Professional United States
Primary
Concomitant
Hyperbilirubinaemia Hospitalization 10/4/2010 47 Male 295 lb 3/24/2011 Other Health Professional Canada
Primary
Concomitant
Bacterial Test Positive Other Serious 11/20/2010 57 Female 3/11/2011 Other Health Professional United States
Primary
Concomitant
Hypoxia Life Threatening 8/25/2010 25 Male 3/17/2011 Other Health Professional United States
Primary
Concomitant
Delirium Other Serious 6/16/2010 53 Male 154 lb 4/8/2011 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 4/15/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Septic Shock Death 4/15/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Death 4/15/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Death 4/15/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Hyperbilirubinaemia Hospitalization 10/4/2010 47 Male 295 lb 4/21/2011 Other Health Professional Canada
Primary
Concomitant
Acute Lymphocytic Leukaemia Death 30 Male 4/29/2011 Physician United States
Primary
Secondary
Concomitant
Neoplasm Malignant Death 56 Male 4/29/2011 Physician United States
Primary
Secondary
Concomitant
Neoplasm Malignant Death 46 Female 4/29/2011 Physician United States
Primary
Secondary
Concomitant
Neoplasm Malignant Death 48 Male 4/29/2011 Physician United States
Primary
Secondary
Concomitant
Neoplasm Malignant Death 58 Female 4/29/2011 Physician United States
Primary
Secondary
Concomitant
Neoplasm Malignant Death 50 Female 4/29/2011 Physician United States
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Death 54 Female 4/29/2011 Physician United States
Primary
Secondary
Concomitant
Cytomegalovirus Gastroenteritis Other Serious 5/11/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 5/16/2011 Physician Serbia
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 5/16/2011 Physician Serbia
Primary
Secondary
Concomitant
Multi-organ Failure Death 5/25/2011 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 5/25/2011 Physician United States
Primary
Secondary
Concomitant
Disease Recurrence Death 5/25/2011 Physician United States
Primary
Secondary
Concomitant
Bacterial Infection Death 5/25/2011 Physician United States
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Death 5/25/2011 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 5/25/2011 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 5/25/2011 Physician United States
Primary
Secondary
Concomitant
Bk Virus Infection Other Serious 10/4/2010 47 Male 295 lb 5/25/2011 Other Health Professional Canada
Primary
Concomitant
Hepatotoxicity Other Serious 8/23/2010 20 Female 104 lb 5/27/2011 Physician France
Primary
Concomitant
Transplant Failure Other Serious 10/26/2009 52 Male 121 lb 6/7/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Other Serious 6/27/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/4/2010 47 Male 295 lb 6/29/2011 Other Health Professional Canada
Primary
Concomitant
Respiratory Failure Death 10/4/2010 47 Male 295 lb 7/1/2011 Other Health Professional Canada
Primary
Concomitant
Diabetes Insipidus Hospitalization 3/21/2011 49 Male 6/28/2011 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/7/2010 49 Male 6/29/2011 Other Health Professional United States
Primary
Concomitant
Pulseless Electrical Activity Death 1/25/2011 66 Male 6/30/2011 Other Health Professional United States
Primary
Concomitant
Csf Protein Increased Other Serious 48 Male 7/5/2011 Other Health Professional Spain
Primary
Secondary
Concomitant
Pancreatic Disorder Other Serious 7/20/2011 Physician Japan
Primary
Concomitant
Bacterial Test Positive Hospitalization 8/25/2010 1 Male 23 lb 7/12/2011 Other Health Professional Canada
Primary
Concomitant
Myelodysplastic Syndrome Death 1/10/2008 10 7/26/2011 Physician United States
Primary
Secondary
Concomitant
Bacterial Infection Death 10/26/2006 6 7/26/2011 Physician United States
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Death 9/29/2008 7 7/26/2011 Physician United States
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Death 9/29/2008 7 7/26/2011 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 1/10/2008 10 7/26/2011 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/29/2011 2 23 lb 7/18/2011 Other Health Professional Canada
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 12/31/2008 9 7/26/2011 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 12/31/2008 9 7/26/2011 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 1/2/2009 13 7/26/2011 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 1/2/2009 13 7/26/2011 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 3/21/2011 61 Male 7/20/2011 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Hospitalization 11/17/2010 57 Female 7/21/2011 Other Health Professional United States
Primary
Concomitant
Wheelchair User Other Serious 8/1/2005 36 Male 170 lb 8/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 7/4/2005 1 Male 19 lb 8/11/2011 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Death 4/15/2011 60 Male 143 lb 8/15/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 4/15/2011 60 Male 143 lb 8/16/2011 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 9/14/2010 49 Female 115 lb 8/25/2011 Physician Japan
Primary
Concomitant
Febrile Neutropenia Death 1/21/2011 60 Female 90 lb 8/26/2011 Physician Japan
Primary
Concomitant
Enterococcal Bacteraemia Hospitalization 10/11/2009 21 Female 101 lb 9/2/2011 Physician Japan
Primary
Concomitant
Bradycardia Life Threatening 1/25/2011 66 Male 9/8/2011 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 2/27/2011 54 Male 9/21/2011 Other Health Professional United States
Primary
Concomitant
Bone Marrow Failure Other Serious 11/10/2008 40 Female 9/29/2011 Physician France
Primary
Secondary
Concomitant
Enterocolitis Bacterial Death 4/27/2009 70 Female 75 lb 10/3/2011 Physician Japan
Primary
Concomitant
Hypertension Other Serious 6/12/2010 53 Male 154 lb 10/5/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Infection Death 68 Female 10/13/2011 Physician Germany
Primary
Concomitant
Cytomegalovirus Infection Death 37 10/13/2011 Physician Germany
Primary
Concomitant
Rotavirus Infection Death 55 10/14/2011 Physician Germany
Primary
Concomitant
Death Death 48 10/14/2011 Physician Germany
Primary
Concomitant
Cytomegalovirus Infection Death 19 10/14/2011 Physician Germany
Primary
Concomitant
Herpes Simplex Death 42 10/14/2011 Physician Germany
Primary
Concomitant
Respiratory Failure Life Threatening 11/17/2010 57 Female 10/10/2011 Physician United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 3/12/2010 59 Male 132 lb 10/17/2011 Physician Japan
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 11/10/2008 40 Female 10/18/2011 Physician United States
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 11/10/2008 40 Female 10/18/2011 United States
Primary
Secondary
Concomitant
Cell Death Other Serious 29 Female 10/27/2011 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 3/24/2011 74 Female 101 lb 10/28/2011 Physician Japan
Primary
Concomitant
Bone Marrow Failure Other Serious 11/10/2008 40 Female 10/31/2011 United States
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 11/10/2008 40 Female 10/31/2011 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 42 11/1/2011 Physician Germany
Primary
Concomitant
Death Death 55 11/1/2011 Physician Germany
Primary
Concomitant
Graft Versus Host Disease Death 12/6/2011 Other Health Professional China
Primary
Concomitant
Pericardial Haemorrhage Other Serious 9/1/2006 38 Male 190 lb 12/12/2011 Physician Netherlands
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/14/2010 49 Female 115 lb 12/14/2011 Physician Japan
Primary
Concomitant
Staphylococcal Infection Other Serious 1/21/2011 60 Female 90 lb 12/15/2011 Physician Japan
Primary
Concomitant
Septic Shock Life Threatening 8/25/2010 25 Male 12/13/2011 Other Health Professional United States
Primary
Concomitant
Tachycardia Life Threatening 8/25/2010 25 Male 12/13/2011 Other Health Professional United States
Primary
Concomitant
Hepatic Congestion Life Threatening 8/25/2010 25 Male 12/13/2011 Other Health Professional United States
Primary
Concomitant
Aspergillus Test Positive Life Threatening 4/14/2010 60 Male 110 lb 12/23/2011 Physician Japan
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 4/15/2011 60 Male 143 lb 12/30/2011 Physician Japan
Primary
Concomitant
Diarrhoea Other Serious 4/11/2011 52 Female 126 lb 1/3/2012 Physician Japan
Primary
Concomitant
Renal Tubular Necrosis Death 2/27/2011 54 Male 12/28/2011 United States
Primary
Concomitant

Drug Data