Dactinomycin



Indications and Reactions:

Role Indications Reactions
Primary
Choriocarcinoma 15.0%
Gestational Trophoblastic Tumour 13.1%
Rhabdomyosarcoma 12.6%
Germ Cell Cancer 9.7%
Nephroblastoma 8.7%
Benign Hydatidiform Mole 6.8%
Lung Neoplasm 5.8%
Prophylaxis Of Nausea And Vomiting 5.8%
Drug Use For Unknown Indication 3.9%
Malignant Melanoma 3.4%
Primitive Neuroectodermal Tumour 2.9%
Sarcoma Metastatic 2.4%
Ewing's Sarcoma 1.5%
Fibrosarcoma 1.5%
Renal Neoplasm 1.5%
Undifferentiated Sarcoma 1.5%
Astrocytoma 1.0%
Chemotherapy 1.0%
Hypertension 1.0%
Immunosuppressant Drug Therapy 1.0%
Venoocclusive Disease 9.6%
Post Procedural Complication 7.7%
Sepsis 7.7%
Vomiting 7.7%
Pyrexia 5.8%
Respiratory Failure 5.8%
Troponin Increased 5.8%
Uterine Haemorrhage 5.8%
Venoocclusive Liver Disease 5.8%
White Blood Cell Count Decreased 5.8%
Anaemia 3.8%
Neutropenic Sepsis 3.8%
Ototoxicity 3.8%
Staphylococcal Infection 3.8%
Staphylococcus Test Positive 3.8%
Tooth Malformation 3.8%
Weight Increased 3.8%
Ascites 1.9%
Blood Potassium Decreased 1.9%
Febrile Bone Marrow Aplasia 1.9%
Secondary
Rhabdomyosarcoma 21.2%
Sarcoma Metastatic 12.9%
Ewing's Sarcoma 10.7%
Product Used For Unknown Indication 10.0%
Neoplasm Malignant 9.7%
Foetal Exposure During Pregnancy 7.1%
Gestational Trophoblastic Tumour 4.3%
Bone Sarcoma 4.1%
Sarcoma 3.8%
Nephroblastoma 2.9%
Choriocarcinoma 2.3%
Drug Use For Unknown Indication 2.1%
Acute Lymphocytic Leukaemia 2.0%
Ovarian Germ Cell Cancer 1.6%
Germ Cell Cancer 1.4%
Malignant Melanoma 1.3%
Breast Cancer 0.8%
Malignant Melanoma Stage Iii 0.7%
Chemotherapy 0.5%
Metastatic Choriocarcinoma 0.4%
Febrile Neutropenia 13.1%
Mucosal Inflammation 13.1%
Thyroid Cancer 9.0%
Febrile Bone Marrow Aplasia 6.9%
Respiratory Failure 6.9%
Epistaxis 4.8%
Off Label Use 4.8%
Treatment Related Secondary Malignancy 4.5%
Ototoxicity 4.2%
Vomiting 4.2%
Premature Baby 3.5%
Weight Decreased 3.5%
Cellulitis 3.1%
Sepsis 3.1%
Candida Test Positive 2.8%
Pyrexia 2.8%
Thrombocytopenia 2.8%
Tachycardia 2.4%
Toxicity To Various Agents 2.4%
Myelitis 2.1%
Concomitant
Rhabdomyosarcoma 15.3%
Chemotherapy 14.0%
Nuclear Magnetic Resonance Imaging 10.8%
Nephroblastoma 8.1%
Ewing's Sarcoma 6.8%
Metastases To Lung 6.3%
Product Used For Unknown Indication 4.5%
Prophylaxis 4.5%
Choriocarcinoma 3.6%
Malignant Melanoma 3.2%
Febrile Neutropenia 2.7%
Neuroblastoma 2.7%
Testis Cancer 2.7%
B-cell Lymphoma 2.3%
Gestational Trophoblastic Tumour 2.3%
Prophylaxis Of Nausea And Vomiting 2.3%
Sarcoma 2.3%
Teratoma 2.3%
Cord Blood Transplant Therapy 1.8%
Nuclear Magnetic Resonance Imaging Brain 1.8%
Thrombocytopenia 28.3%
Drug Toxicity 8.7%
Nephrogenic Systemic Fibrosis 6.5%
Treatment Failure 6.5%
Vomiting 6.5%
Ejection Fraction Decreased 4.3%
Interstitial Lung Disease 4.3%
Intracardiac Thrombus 4.3%
Renal Tubular Disorder 4.3%
Xerosis 4.3%
Agranulocytosis 2.2%
Back Pain 2.2%
Blood Human Chorionic Gonadotropin Increased 2.2%
Blood Pressure Inadequately Controlled 2.2%
Death 2.2%
Drug Hypersensitivity 2.2%
Drug Interaction 2.2%
Encephalopathy 2.2%
Exsanguination 2.2%
Faecal Incontinence 2.2%