Dactinomycin combined with Etoposide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pancytopenia Other Serious 11/15/2004 36 Male 1/10/2006 Consumer United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 11/15/2004 36 Male 1/24/2006 Consumer United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 36 Male 161 lb 3/16/2006 Japan
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Other Serious 9 Female 7/6/2006 Other Health Professional United States
Primary
Secondary
Renal Cell Carcinoma Stage Unspecified Other Serious 9 Female 6/26/2006 Other Health Professional United States
Primary
Secondary
Renal Cell Carcinoma Stage Unspecified Other Serious 9 Female 7/13/2006 United States
Primary
Secondary
Mucoepidermoid Carcinoma Other Serious 13 Female 7/25/2006 Physician Turkey
Primary
Secondary
Primitive Neuroectodermal Tumour Death 10 Male 7/25/2006 Physician Turkey
Primary
Secondary
Therapeutic Response Decreased Other Serious 37 Female 7/25/2006 Physician Japan
Primary
Secondary
Treatment Related Secondary Malignancy Other Serious 15 Female 8/3/2006 Consumer United States
Primary
Secondary
Treatment Related Secondary Malignancy Death 10 Male 8/3/2006 Consumer United States
Primary
Secondary
Treatment Related Secondary Malignancy Other Serious 13 Female 8/3/2006 Consumer United States
Primary
Secondary
Solitary Kidney Secondary Other Serious 9 Female 8/14/2006 Physician United States
Primary
Secondary
Respiratory Failure Required Intervention 31 Female 10/23/2006 Japan
Primary
Secondary
Concomitant
Neutropenic Sepsis Death Female 10/23/2006 Physician Egypt
Primary
Secondary
Neutropenic Sepsis Death Female 10/23/2006 Physician Egypt
Primary
Secondary
Respiratory Failure Required Intervention 6/25/2004 31 Female 11/3/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 6/25/2004 31 Female 11/3/2006 Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization Female 2/14/2007 Consumer United States
Primary
Secondary
Pyrexia Other Serious 12/23/2006 Female 163 lb 4/4/2007 Physician Bahrain
Primary
Concomitant
Respiratory Failure Hospitalization 6 Female 4/13/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Death 3 Male 4/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Stridor Death 6 Female 4/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Renal Tubular Disorder Other Serious 4/27/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 3 Male 4/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Interstitial Lung Disease Death 3 Male 5/9/2007 United Kingdom
Primary
Secondary
Concomitant
Sputum Culture Positive Death 6 Female 5/1/2007 United Kingdom
Primary
Secondary
Weaning Failure Death 2 Male 5/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Stridor Death 6 Female 5/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Weaning Failure Death 3 Male 5/4/2007 United Kingdom
Primary
Secondary
Uterine Haemorrhage Hospitalization 32 Female 5/24/2007 Japan
Primary
Secondary
Respiratory Failure Other Serious 3 Male 6/1/2007 United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3 Male 6/4/2007 United Kingdom
Primary
Secondary
Respiratory Failure Death 3 Male 5/25/2007 United Kingdom
Primary
Secondary
Uterine Haemorrhage Life Threatening 6/4/2005 Female 6/4/2007 Japan
Primary
Secondary
Uterine Haemorrhage Life Threatening 6/4/2005 32 Female 6/6/2007 Other Health Professional Japan
Primary
Secondary
Respiratory Failure Other Serious 3 Male 6/14/2007 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Failure Other Serious 3 Male 6/19/2007 United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3 Male 6/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Skin Reaction Death 3 Male 6/20/2007 United Kingdom
Primary
Secondary
Respiratory Failure Hospitalization 3 Male 6/29/2007 United Kingdom
Primary
Secondary
Concomitant
Streptococcal Infection Death 6 Female 7/3/2007 United Kingdom
Primary
Secondary
Weaning Failure Hospitalization 3 Male 7/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Thrombocytopenia Life Threatening 20 Male 7/2/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 15 Female 7/2/2007 Japan
Primary
Secondary
Concomitant
Viral Myocarditis Life Threatening 16 Male 7/2/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 20 Female 7/2/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 23 Female 7/2/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 15 Female 7/2/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 15 Female 7/2/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 25 Female 7/2/2007 Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3 Male 7/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Ototoxicity Death 3 Male 7/17/2007 United Kingdom
Primary
Secondary
Ulcer Other Serious 1/1/2000 14 Male 7/13/2007 Physician United States
Primary
Secondary
Concomitant
Stridor Death 6 Female 7/10/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 6 Female 7/24/2007 United Kingdom
Primary
Secondary
Respiratory Failure Hospitalization 3 Male 8/1/2007 United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 6 Female 8/7/2007 United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Other Serious 9/14/2007 Other Health Professional United States
Primary
Secondary
Osteomalacia Hospitalization 12/1/2002 33 Female 9/20/2007 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 6 Female 9/24/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 9/18/2007 Physician United Kingdom
Primary
Secondary
Intra-abdominal Haemorrhage Death 9/18/2007 United Kingdom
Primary
Secondary
Sepsis Death 9/18/2007 Physician United Kingdom
Primary
Secondary
Sepsis Death 9/18/2007 Physician United Kingdom
Primary
Secondary
Sepsis Death 9/18/2007 Physician United Kingdom
Primary
Secondary
Pneumonitis Hospitalization 6 Female 9/27/2007 Physician United Kingdom
Primary
Concomitant
Sepsis Death 10/3/2007 United Kingdom
Primary
Secondary
Sepsis Death 10/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Thrombocytopenia Life Threatening 15 Female 10/18/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 25 Female 10/18/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Death 20 Female 10/18/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 23 Female 10/18/2007 Japan
Primary
Secondary
Concomitant
Sepsis Death 10/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 10/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 20 Male 10/19/2007 Japan
Primary
Secondary
Concomitant
Sepsis Death 10/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death Male 10/26/2007 United Kingdom
Primary
Secondary
Sepsis Death Unknown 10/22/2007 United Kingdom
Primary
Secondary
Intra-abdominal Haemorrhage Death 10/22/2007 Physician United Kingdom
Primary
Secondary
Intra-abdominal Haemorrhage Death 10/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Pneumonitis Hospitalization 6 Female 11/28/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 8/7/2006 4 Male 28 lb 1/29/2008 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3 Male 2/8/2008 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Failure Hospitalization 3 Male 2/21/2008 United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 6 Female 3/5/2008 United Kingdom
Primary
Secondary
Metastasis Other Serious Female 3/31/2008 Consumer United Kingdom
Primary
Secondary
Exsanguination Life Threatening 10/23/1986 23 Male 154 lb 3/31/2008 Physician United Kingdom
Primary
Concomitant
Stridor Hospitalization 6 Female 4/14/2008 United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 6 Female 4/24/2008 Consumer United States
Primary
Secondary
Concomitant
Sputum Culture Positive Hospitalization 6 Female 4/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 6 Female 5/5/2008 United Kingdom
Primary
Secondary
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 5/6/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Intra-abdominal Haemorrhage Death 8/8/1998 7/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Deafness Unilateral Other Serious 11 Male 8/13/2008 Other Health Professional Brazil
Primary
Secondary
Ear Infection Other Serious 5 Female 8/13/2008 Other Health Professional Brazil
Primary
Secondary
Deafness Bilateral Other Serious 15 Female 8/13/2008 Other Health Professional Brazil
Primary
Secondary
Tinnitus Other Serious 19 Female 8/13/2008 Other Health Professional Brazil
Primary
Secondary
Pruritus Other Serious 10 Female 8/13/2008 Other Health Professional Brazil
Primary
Secondary
Tinnitus Other Serious 27 Male 8/13/2008 Other Health Professional Brazil
Primary
Secondary
Tinnitus Other Serious 20 Female 8/13/2008 Other Health Professional Brazil
Primary
Secondary
Ear Pain Other Serious 19 Female 8/13/2008 Other Health Professional Brazil
Primary
Secondary
Intra-abdominal Haemorrhage Death Unknown 8/8/2008 United Kingdom
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 8/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 8/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 15 Female 10/8/2008 Other Health Professional Japan
Primary
Secondary
Pulmonary Fibrosis Other Serious 15 Female 10/14/2008 Other Health Professional Japan
Primary
Secondary
Bone Sarcoma Other Serious 10/1/2007 12 Male 11/10/2008 Physician Japan
Primary
Secondary
Bone Sarcoma Other Serious 10/1/2007 12 Male 11/12/2008 Japan
Primary
Secondary
Bone Sarcoma Other Serious 10/1/2007 12 Male 11/19/2008 Physician Japan
Primary
Secondary
Drug Hypersensitivity Other Serious 33 Female 6/30/2008 United Kingdom
Primary
Concomitant
Interstitial Lung Disease Other Serious 11 Female 12/2/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Bone Sarcoma Other Serious 10/1/2007 12 Male 12/2/2008 Japan
Primary
Secondary
Thrombocytopenia Other Serious 27 Female 12/30/2008 Physician Germany
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 7 Male 1/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 7 Male 1/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 7 Male 1/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Thyroid Cancer Other Serious 7 Male 1/9/2009 United Kingdom
Primary
Secondary
Thyroid Cancer Other Serious 7 Male 1/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 7 Male 1/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Thyroid Cancer Other Serious 7 Male 1/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 7 Male 1/15/2009 United Kingdom
Primary
Secondary
Thyroid Cancer Other Serious 7 Male 1/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Thyroid Cancer Other Serious 7 Male 1/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Thyroid Cancer Other Serious 2/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Required Intervention 2 Male 2/11/2009 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 7 Male 2/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Other Serious 2 Male 3/18/2009 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Hepatic Vein Occlusion Other Serious 21 Male 3/18/2009 Taiwan, Province Of China
Primary
Secondary
Venoocclusive Liver Disease Other Serious 2 Male 3/25/2009 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Thyroid Cancer Other Serious 7 Male 3/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Weight Increased Hospitalization 3/12/2009 Male 31 lb 3/23/2009 United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 3/12/2009 Male 31 lb 3/30/2009 United States
Primary
Secondary
Concomitant
Vomiting Death 5 Female 5/29/2009 Physician Japan
Primary
Secondary
Concomitant
Sudden Death Death 5 Female 6/19/2009 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 1/1/2007 62 Female 11/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Toxic Epidermal Necrolysis Death 62 Female 11/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 30 Female 12/8/2009 Other Health Professional India
Primary
Secondary
Concomitant
Capillary Leak Syndrome Death Unknown 12/14/2009 Italy
Primary
Secondary
Metastases To Breast Other Serious Female 1/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Hepatitis B Other Serious 35 Female 2/18/2010 Turkey
Primary
Secondary
Hepatitis B Other Serious 35 Male 2/28/2010 Other Health Professional Turkey
Primary
Secondary
Hepatitis B Other Serious 35 Female 3/8/2010 Turkey
Primary
Secondary
Uterine Perforation Hospitalization 25 Female 6/17/2010 Other Health Professional Switzerland
Primary
Secondary
Uterine Perforation Hospitalization 25 Female 6/30/2010 Physician Switzerland
Primary
Secondary
Uterine Perforation Hospitalization 25 Female 6/30/2010 Physician Switzerland
Primary
Secondary
Thrombocytopenia Life Threatening 27 Female 10/25/2010 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 27 Female 10/25/2010 Physician Germany
Primary
Secondary
Concomitant

Drug Data