Dactinomycin combined with Ifosfamide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myelodysplastic Syndrome Other Serious 36 Male 161 lb 3/16/2006 Japan
Primary
Secondary
Concomitant
Haemorrhagic Cerebral Infarction Hospitalization 4 Female 5/12/2006 Other Health Professional Turkey
Primary
Concomitant
Treatment Related Secondary Malignancy Death 5 Male 8/3/2006 Consumer United States
Primary
Secondary
Treatment Related Secondary Malignancy Death 2 Female 8/3/2006 Consumer United States
Primary
Secondary
Hypomania Other Serious 16 Male 9/1/2006 Other Health Professional
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 6 Female 4/13/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Death 3 Male 4/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Stridor Death 6 Female 4/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Renal Tubular Disorder Other Serious 4/27/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 3 Male 4/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Interstitial Lung Disease Death 3 Male 5/9/2007 United Kingdom
Primary
Secondary
Concomitant
Sputum Culture Positive Death 6 Female 5/1/2007 United Kingdom
Primary
Secondary
Weaning Failure Death 2 Male 5/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Stridor Death 6 Female 5/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Weaning Failure Death 3 Male 5/4/2007 United Kingdom
Primary
Secondary
Respiratory Failure Other Serious 3 Male 6/1/2007 United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3 Male 6/4/2007 United Kingdom
Primary
Secondary
Respiratory Failure Death 3 Male 5/25/2007 United Kingdom
Primary
Secondary
Stomatitis Hospitalization 5/26/2007 2 Male 5/31/2007 Other Health Professional France
Primary
Secondary
Respiratory Failure Other Serious 3 Male 6/14/2007 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Failure Other Serious 3 Male 6/19/2007 United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3 Male 6/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Skin Reaction Death 3 Male 6/20/2007 United Kingdom
Primary
Secondary
Respiratory Failure Hospitalization 3 Male 6/29/2007 United Kingdom
Primary
Secondary
Concomitant
Streptococcal Infection Death 6 Female 7/3/2007 United Kingdom
Primary
Secondary
Weaning Failure Hospitalization 3 Male 7/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Failure Hospitalization 3 Male 7/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Ototoxicity Death 3 Male 7/17/2007 United Kingdom
Primary
Secondary
Ulcer Other Serious 1/1/2000 14 Male 7/13/2007 Physician United States
Primary
Secondary
Concomitant
Stridor Death 6 Female 7/10/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 6 Female 7/24/2007 United Kingdom
Primary
Secondary
Respiratory Failure Hospitalization 3 Male 8/1/2007 United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 6 Female 8/7/2007 United Kingdom
Primary
Secondary
Stress Fracture Hospitalization 12/1/2002 33 Female 8/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 9/14/2007 Other Health Professional United States
Primary
Secondary
Osteomalacia Hospitalization 12/1/2002 33 Female 9/17/2007 Consumer United States
Primary
Secondary
Concomitant
Osteomalacia Hospitalization 12/1/2002 33 Female 9/20/2007 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 6 Female 9/24/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 6 Female 9/27/2007 Physician United Kingdom
Primary
Concomitant
Pneumonitis Hospitalization 6 Female 11/28/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3 Male 2/8/2008 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Failure Hospitalization 3 Male 2/21/2008 United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 6 Female 3/5/2008 United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 2/29/2008 Female 29 lb 3/13/2008 United States
Primary
Secondary
Concomitant
Stridor Hospitalization 6 Female 4/14/2008 United Kingdom
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 13 Female 4/18/2008 Other Health Professional Korea, Republic Of
Primary
Secondary
Pneumonitis Hospitalization 6 Female 4/24/2008 Consumer United States
Primary
Secondary
Concomitant
Sputum Culture Positive Hospitalization 6 Female 4/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 6 Female 5/5/2008 United Kingdom
Primary
Secondary
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 5/6/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 13 Female 8/13/2008 Consumer Japan
Primary
Secondary
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 8/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 8/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 11 Female 12/2/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 7 Male 1/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 7 Male 1/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 7 Male 1/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Thyroid Cancer Other Serious 7 Male 1/9/2009 United Kingdom
Primary
Secondary
Viral Upper Respiratory Tract Infection Hospitalization 12/12/2008 Male 1/14/2009 Consumer United Kingdom
Primary
Secondary
Thyroid Cancer Other Serious 7 Male 1/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 7 Male 1/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Pyrexia Other Serious Male 1/21/2009 Consumer United Kingdom
Primary
Secondary
Thyroid Cancer Other Serious 7 Male 1/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 7 Male 1/15/2009 United Kingdom
Primary
Secondary
Pyrexia Other Serious 1/11/2009 Male 1/26/2009 Consumer United Kingdom
Primary
Secondary
Thyroid Cancer Other Serious 7 Male 1/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Thyroid Cancer Other Serious 7 Male 1/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Pyrexia Other Serious 1/11/2009 Male 2/5/2009 Consumer United Kingdom
Primary
Secondary
Thyroid Cancer Other Serious 2/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Required Intervention 2 Male 2/11/2009 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 7 Male 2/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Other Serious 2 Male 3/18/2009 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Hepatic Vein Occlusion Other Serious 21 Male 3/18/2009 Taiwan, Province Of China
Primary
Secondary
Venoocclusive Liver Disease Other Serious 2 Male 3/25/2009 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Thyroid Cancer Other Serious 7 Male 3/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Capillary Leak Syndrome Death Unknown 12/14/2009 Italy
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious 8/31/2010 9 Male 72 lb 12/2/2010 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/25/2010 9 Female 35 lb 11/19/2010 Other Health Professional Norway
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 12/23/2010 9 Male 41 lb 1/10/2011 Physician France
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 12/23/2010 9 Male 42 lb 1/27/2011 Physician France
Primary
Secondary
Concomitant
Fanconi Syndrome Other Serious 1 2/23/2011 Physician France
Primary
Secondary
Fanconi Syndrome Other Serious 2 2/23/2011 Other Health Professional France
Primary
Secondary
Fanconi Syndrome Other Serious 1 2/23/2011 Other Health Professional France
Primary
Secondary
Fanconi Syndrome Other Serious 2 2/23/2011 Physician France
Primary
Secondary
Febrile Bone Marrow Aplasia Hospitalization 12/23/2010 9 Male 42 lb 3/4/2011 Physician France
Primary
Secondary
Concomitant
Fanconi Syndrome Other Serious 4 Male 3/21/2011 Physician United Kingdom
Primary
Secondary
Mucosal Inflammation Hospitalization 11/7/2010 9 Male 42 lb 4/14/2011 Physician France
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 4/29/2011 17 Female 101 lb 5/6/2011 Physician France
Primary
Secondary
Mucosal Inflammation Other Serious 3/12/2011 14 Female 88 lb 5/10/2011 Physician France
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 4/29/2011 17 Female 101 lb 5/17/2011 Physician France
Primary
Secondary
Peripheral Sensorimotor Neuropathy Other Serious 8/31/2010 9 Male 69 lb 5/24/2011 Other Health Professional France
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 3/12/2011 14 Female 88 lb 5/24/2011 Physician France
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 3/12/2011 14 Female 86 lb 6/3/2011 Physician France
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 3/12/2011 14 Female 80 lb 6/17/2011 Physician France
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 4/29/2011 17 Female 101 lb 6/23/2011 Physician France
Primary
Secondary
Febrile Bone Marrow Aplasia Hospitalization 8/31/2010 9 Male 77 lb 6/23/2011 Other Health Professional France
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 3/12/2011 14 Female 80 lb 6/24/2011 Physician France
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 7 Male 6/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Neoplasm Malignant Other Serious 7 Male 6/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 3/12/2011 14 Female 80 lb 7/5/2011 Physician France
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 2 Male 7/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Thyroid Cancer Other Serious 7 Male 7/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Thyroid Cancer Other Serious 7 Male 7/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Thyroid Cancer Other Serious 7 Male 7/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Thyroid Cancer Other Serious 7 Male 6/29/2011 Physician United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 7/15/2011 2 Female 28 lb 7/27/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 3/12/2011 14 Female 83 lb 7/27/2011 Physician France
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/15/2011 2 Female 28 lb 8/11/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 15 Female 8/12/2011 Other Health Professional Japan
Primary
Secondary
Vomiting Other Serious 3/12/2011 14 Female 83 lb 8/18/2011 Physician France
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 2/11/2011 17 Male 134 lb 8/22/2011 Consumer United States
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 8/11/2011 4 Male 33 lb 8/30/2011 Pharmacist Germany
Primary
Concomitant
Mucosal Inflammation Hospitalization 7/15/2011 2 Female 26 lb 9/1/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Candida Test Positive Hospitalization 7/15/2011 2 Female 26 lb 9/9/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Post Procedural Haematoma Hospitalization 12/14/2010 7 Male 66 lb 9/12/2011 Physician France
Primary
Secondary
Concomitant
Candida Test Positive Other Serious 7/15/2011 2 Female 26 lb 9/14/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective For Unapproved Indication Other Serious Male 9/19/2011 Other Health Professional Poland
Primary
Secondary
Mucosal Inflammation Other Serious 7/15/2011 2 Female 26 lb 9/21/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 12/14/2010 7 Male 58 lb 9/22/2011 Physician France
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 7/15/2011 2 Female 26 lb 9/23/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Peripheral Sensorimotor Neuropathy Other Serious 8/31/2010 9 Male 77 lb 9/23/2011 Other Health Professional France
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 16 Male 10/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 3/3/2010 6 Male 64 lb 10/4/2011 France
Primary
Secondary
Candida Test Positive Hospitalization 7/15/2011 2 Female 28 lb 10/5/2011 United Kingdom
Primary
Secondary
Concomitant
Renal Tubular Acidosis Other Serious 16 Male 10/17/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/15/2011 2 Female 28 lb 10/18/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Death 16 Male 10/20/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Tubular Disorder Other Serious 6/24/2011 20 Male 10/24/2011 Physician Germany
Primary
Secondary
Concomitant
Radiation Injury Other Serious 16 Male 10/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 3/3/2010 6 Male 64 lb 10/26/2011 Consumer United Kingdom
Primary
Secondary
Fungaemia Hospitalization 7/15/2011 3 Female 24 lb 10/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 8 Female 10/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Hypertension Other Serious 16 Male 10/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/18/2010 13 Male 119 lb 10/31/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Candida Test Positive Hospitalization 7/15/2011 2 Female 28 lb 11/10/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 11/7/2010 9 Male 42 lb 11/11/2011 Physician France
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 7/15/2011 2 Female 28 lb 11/14/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Encephalopathy Other Serious Female 11/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Pancreatitis Hospitalization 16 Male 11/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pathological Fracture Other Serious 14 Female 11/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Renal Tubular Disorder Other Serious 13 Female 11/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 7/15/2011 2 Female 28 lb 11/29/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Disease Complication Other Serious 44 Male 11/28/2011 Other Health Professional Germany
Primary
Secondary
Epistaxis Hospitalization 7/15/2011 2 Female 28 lb 12/5/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/15/2011 2 Female 28 lb 12/7/2011 United Kingdom
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 7/15/2011 2 Female 28 lb 12/8/2011 United Kingdom
Primary
Secondary
Concomitant
Fluid Intake Reduced Hospitalization 11/21/2011 2 Male 22 lb 12/12/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/15/2011 3 Female 26 lb 12/12/2011 Consumer United Kingdom
Primary
Secondary
Concomitant

Drug Data