Cyclophosphamide combined with Dactinomycin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Treatment Related Secondary Malignancy Other Serious 9 Female 7/6/2006 Other Health Professional United States
Primary
Secondary
Renal Cell Carcinoma Stage Unspecified Other Serious 9 Female 6/26/2006 Other Health Professional United States
Primary
Secondary
Stem Cell Transplant Other Serious 4 Female 7/14/2006 Other Health Professional Japan
Primary
Secondary
Renal Cell Carcinoma Stage Unspecified Other Serious 9 Female 7/13/2006 United States
Primary
Secondary
Mucoepidermoid Carcinoma Other Serious 13 Female 7/25/2006 Physician Turkey
Primary
Secondary
Primitive Neuroectodermal Tumour Death 10 Male 7/25/2006 Physician Turkey
Primary
Secondary
Therapeutic Response Decreased Other Serious 37 Female 7/25/2006 Physician Japan
Primary
Secondary
Acute Myeloid Leukaemia Death 2 Female 8/2/2006 Other Health Professional Turkey
Primary
Secondary
Treatment Related Secondary Malignancy Other Serious 15 Female 8/3/2006 Consumer United States
Primary
Secondary
Treatment Related Secondary Malignancy Death 6 Female 8/3/2006 Consumer United States
Primary
Secondary
Treatment Related Secondary Malignancy Death 13 Female 8/3/2006 Consumer United States
Primary
Secondary
Treatment Related Secondary Malignancy Death 5 Male 8/3/2006 Consumer United States
Primary
Secondary
Treatment Related Secondary Malignancy Death 10 Male 8/3/2006 Consumer United States
Primary
Secondary
Treatment Related Secondary Malignancy Other Serious 13 Female 8/3/2006 Consumer United States
Primary
Secondary
Treatment Related Secondary Malignancy Death 2 Female 8/3/2006 Consumer United States
Primary
Secondary
Treatment Related Secondary Malignancy Death 2 Female 8/3/2006 Consumer United States
Primary
Secondary
Recurrent Cancer Other Serious 4 Female 8/1/2006 Other Health Professional Japan
Primary
Secondary
Acute Myeloid Leukaemia Death 2 Female 8/8/2006 Other Health Professional Turkey
Primary
Secondary
Treatment Related Secondary Malignancy Death 2 Female 8/8/2006 Turkey
Primary
Secondary
Solitary Kidney Secondary Other Serious 9 Female 8/14/2006 Physician United States
Primary
Secondary
Venoocclusive Disease Death 10/6/2006 Physician Germany
Primary
Secondary
Respiratory Failure Required Intervention 31 Female 10/23/2006 Japan
Primary
Secondary
Concomitant
Respiratory Failure Required Intervention 6/25/2004 31 Female 11/3/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 6/25/2004 31 Female 11/3/2006 Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 9/4/2006 12 Male 11/28/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/4/2006 12 Male 12/18/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/27/2007 35 Female 3/22/2007 Physician Japan
Primary
Secondary
Concomitant
Surgery Other Serious 1/1/2001 66 Male 4/6/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/27/2007 35 Female 4/4/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/27/2007 35 Female 4/19/2007 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 20 Male 7/2/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 15 Female 7/2/2007 Japan
Primary
Secondary
Concomitant
Viral Myocarditis Life Threatening 16 Male 7/2/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 20 Female 7/2/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 23 Female 7/2/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 15 Female 7/2/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 15 Female 7/2/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 25 Female 7/2/2007 Japan
Primary
Secondary
Concomitant
Ulcer Other Serious 1/1/2000 14 Male 7/13/2007 Physician United States
Primary
Secondary
Concomitant
Mucoepidermoid Carcinoma Other Serious 16 Female 8/9/2007 Other Health Professional United States
Primary
Secondary
Mucoepidermoid Carcinoma Other Serious 17 Male 8/9/2007 Other Health Professional United States
Primary
Secondary
Stress Fracture Hospitalization 12/1/2002 33 Female 8/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 9/14/2007 Other Health Professional United States
Primary
Secondary
Osteomalacia Hospitalization 12/1/2002 33 Female 9/17/2007 Consumer United States
Primary
Secondary
Concomitant
Osteomalacia Hospitalization 12/1/2002 33 Female 9/20/2007 Consumer United States
Primary
Secondary
Concomitant
Tooth Malformation Disability 3 Female 10/11/2007 Physician Japan
Primary
Secondary
Tooth Hypoplasia Disability 3 Female 10/15/2007 Physician Japan
Primary
Secondary
Thrombocytopenia Life Threatening 15 Female 10/18/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 25 Female 10/18/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Death 20 Female 10/18/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 23 Female 10/18/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 20 Male 10/19/2007 Japan
Primary
Secondary
Concomitant
Soft Tissue Necrosis Hospitalization 10/27/2007 Female 99 lb 11/2/2007 United States
Primary
Secondary
Concomitant
Vulval Disorder Hospitalization 10/27/2007 Female 99 lb 11/15/2007 Canada
Primary
Secondary
Testis Cancer Other Serious 30 Male 12/12/2007 Physician United States
Primary
Secondary
Concomitant
Death Death 4/15/1982 12 Female 12/6/2007 Consumer Canada
Primary
Concomitant
Febrile Neutropenia Life Threatening 11/30/2006 16 Female 1/2/2008 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Disease Life Threatening 6/29/2005 Male 99 lb 1/2/2008 United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 8/7/2006 4 Male 28 lb 1/29/2008 Physician Japan
Primary
Secondary
Concomitant
Venous Occlusion Other Serious 2 Male 2/22/2008 Other Health Professional Turkey
Primary
Secondary
Neuropathy Peripheral Other Serious 10 Male 3/6/2008 Other Health Professional Turkey
Primary
Secondary
Neuropathy Peripheral Other Serious 10 Male 3/7/2008 Other Health Professional Turkey
Primary
Secondary
Exsanguination Life Threatening 10/23/1986 23 Male 154 lb 3/31/2008 Physician United Kingdom
Primary
Concomitant
Venoocclusive Disease Hospitalization 2 Male 3/31/2008
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious Female 4/8/2008 Other Health Professional Korea, Republic Of
Primary
Secondary
Thyroid Cancer Other Serious Female 4/10/2008 Korea, Republic Of
Primary
Secondary
Thyroid Cancer Other Serious 13 Female 4/10/2008 Other Health Professional Korea, Republic Of
Primary
Secondary
Weight Decreased Hospitalization 3/30/2008 Male 203 lb 4/7/2008 United States
Primary
Secondary
Weight Decreased Hospitalization 3/30/2008 Male 203 lb 4/10/2008 United States
Primary
Secondary
Thyroid Cancer Other Serious 13 Female 4/18/2008 Other Health Professional Korea, Republic Of
Primary
Secondary
Vomiting 3/18/2008 Female 30 lb 5/23/2008 United States
Primary
Secondary
Venous Pressure Jugular Increased Hospitalization 24 Male 6/2/2008 United States
Primary
Secondary
Vomiting Hospitalization 3/30/2008 Male 203 lb 6/9/2008 United States
Primary
Secondary
Cardiomyopathy Death 2 Female 6/24/2008 Japan
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 6/13/2008 Female 141 lb 6/19/2008 United States
Primary
Secondary
Stomatitis Hospitalization 6/13/2008 Female 141 lb 7/7/2008 United States
Primary
Secondary
Thyroid Cancer Other Serious 13 Female 8/13/2008 Consumer Japan
Primary
Secondary
Deafness Unilateral Other Serious 11 Male 8/13/2008 Other Health Professional Brazil
Primary
Secondary
Ear Infection Other Serious 5 Female 8/13/2008 Other Health Professional Brazil
Primary
Secondary
Deafness Bilateral Other Serious 15 Female 8/13/2008 Other Health Professional Brazil
Primary
Secondary
Tinnitus Other Serious 19 Female 8/13/2008 Other Health Professional Brazil
Primary
Secondary
Pruritus Other Serious 10 Female 8/13/2008 Other Health Professional Brazil
Primary
Secondary
Tinnitus Other Serious 27 Male 8/13/2008 Other Health Professional Brazil
Primary
Secondary
Tinnitus Other Serious 20 Female 8/13/2008 Other Health Professional Brazil
Primary
Secondary
Ear Pain Other Serious 19 Female 8/13/2008 Other Health Professional Brazil
Primary
Secondary
Pulmonary Fibrosis Other Serious 15 Female 10/8/2008 Other Health Professional Japan
Primary
Secondary
Pulmonary Fibrosis Other Serious 15 Female 10/14/2008 Other Health Professional Japan
Primary
Secondary
Bone Sarcoma Other Serious 10/1/2007 12 Male 11/12/2008 Japan
Primary
Secondary
Drug Hypersensitivity Other Serious 33 Female 6/30/2008 United Kingdom
Primary
Concomitant
Bone Sarcoma Other Serious 10/1/2007 12 Male 12/2/2008 Japan
Primary
Secondary
Thrombocytopenia Other Serious 27 Female 12/30/2008 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 11/18/2008 14 Male 93 lb 1/5/2009 Poland
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Sweat Gland Disorder Hospitalization 12 Female 2/2/2009 Other Health Professional United States
Primary
Secondary
Skin Plaque Other Serious 12 Female 2/5/2009 Physician United States
Primary
Concomitant
Cardiomyopathy Death 2 Female 2/19/2009 Japan
Primary
Secondary
Acute Lymphocytic Leukaemia Other Serious 34 Male 2/19/2009 United States
Primary
Secondary
Febrile Neutropenia Hospitalization 12/26/2008 Female 2/26/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/26/2008 Female 2/27/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 11/18/2008 14 Male 93 lb 2/27/2009 Poland
Primary
Secondary
Venoocclusive Liver Disease Other Serious 2 Male 3/18/2009 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Hepatic Vein Occlusion Other Serious 21 Male 3/18/2009 Taiwan, Province Of China
Primary
Secondary
Venoocclusive Liver Disease Other Serious 2 Male 3/25/2009 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Weight Increased Hospitalization 3/12/2009 Male 31 lb 3/23/2009 United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 3/12/2009 Male 31 lb 3/30/2009 United States
Primary
Secondary
Concomitant
Vomiting Death 5 Female 5/29/2009 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1 Male 6/10/2009 Physician Japan
Primary
Concomitant
Sudden Death Death 5 Female 6/19/2009 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 1/1/2007 62 Female 11/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Toxic Epidermal Necrolysis Death 62 Female 11/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Treatment Failure Other Serious Unknown 11/16/2009 India
Primary
Secondary
Concomitant
Treatment Failure Hospitalization Unknown 11/16/2009 India
Primary
Secondary
Concomitant
Treatment Failure Hospitalization Unknown 11/16/2009 India
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 30 Female 12/8/2009 Other Health Professional India
Primary
Secondary
Concomitant
Spinal Cord Disorder Hospitalization 12/3/2009 Male 39 lb 12/11/2009 United States
Primary
Secondary
Capillary Leak Syndrome Death Unknown 12/14/2009 Italy
Primary
Secondary
Spinal Cord Disorder Hospitalization 12/3/2009 Male 39 lb 12/22/2009 United States
Primary
Secondary
Myelitis Other Serious 13 Female 1/8/2010 United States
Primary
Secondary
Myelitis Other Serious 16 Male 1/8/2010 United States
Primary
Secondary
Myelitis Other Serious 13 Female 1/8/2010 United States
Primary
Secondary
Myelitis Other Serious 13 1/11/2010 Physician United States
Primary
Secondary
Concomitant
Myelitis Other Serious 16 1/11/2010 Physician United States
Primary
Secondary
Concomitant
Myelitis Other Serious 13 Female 1/11/2010 Physician United States
Primary
Secondary
Hepatitis B Other Serious 35 Female 2/18/2010 Turkey
Primary
Secondary
Hepatitis B Other Serious 35 Male 2/28/2010 Other Health Professional Turkey
Primary
Secondary
Hepatitis B Other Serious 35 Female 3/8/2010 Turkey
Primary
Secondary
Weight Decreased Other Serious 10 Female 5/17/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Uterine Perforation Hospitalization 25 Female 6/17/2010 Other Health Professional Switzerland
Primary
Secondary
Tumour Lysis Syndrome Other Serious 17 Female 11/26/2010 United States
Primary
Secondary
Mucosal Inflammation Hospitalization 12/23/2010 9 Male 42 lb 1/27/2011 Physician France
Primary
Secondary
Concomitant
Oesophagitis Life Threatening 17 Female 1/21/2011 Physician United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 17 Female 2/8/2011 Physician United States
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 12/23/2010 9 Male 42 lb 3/4/2011 Physician France
Primary
Secondary
Concomitant
Tuberculosis Of Central Nervous System Hospitalization 36 Female 3/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 36 Female 3/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hormone Level Abnormal Hospitalization 36 Female 3/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 36 Female 3/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Gonadotrophin Abnormal Hospitalization 36 Female 3/9/2011 Physician United Kingdom
Primary
Secondary
Blood Human Chorionic Gonadotropin Positive Other Serious 36 Female 3/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 36 Female 3/18/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Meningism Hospitalization 36 Female 3/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Human Chorionic Gonadotropin Increased Hospitalization 1/1/2008 36 Female 3/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Fanconi Syndrome Other Serious 4 Male 3/21/2011 Physician United Kingdom
Primary
Secondary
Tuberculosis Hospitalization 36 Female 3/10/2011 Other Health Professional United Kingdom
Primary
Secondary
Ascites Hospitalization 3/16/2011 3 Female 37 lb 3/17/2011 United States
Primary
Secondary
Encephalitis Viral Hospitalization 36 Female 3/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Human Chorionic Gonadotropin Increased Hospitalization 36 Female 3/30/2011 Physician United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 3/16/2011 3 Female 37 lb 4/4/2011 Other Health Professional New Zealand
Primary
Secondary
Mucosal Inflammation Hospitalization 11/7/2010 9 Male 42 lb 4/14/2011 Physician France
Primary
Secondary
Concomitant

Drug Data