| Primary |
| Pulmonary Arterial Hypertension |
85.7% |
| Pulmonary Hypertension |
8.4% |
| Product Used For Unknown Indication |
1.8% |
| Skin Ulcer |
1.6% |
| Drug Use For Unknown Indication |
0.8% |
| Cor Pulmonale Chronic |
0.4% |
| Digital Ulcer |
0.3% |
| Systemic Sclerosis |
0.2% |
| Drug Exposure During Pregnancy |
0.2% |
| Portopulmonary Hypertension |
0.1% |
| Scleroderma |
0.1% |
| Maternal Exposure During Pregnancy |
0.1% |
| Scleroderma Renal Crisis |
0.1% |
| Raynaud's Phenomenon |
0.1% |
| Accidental Exposure |
0.1% |
| Eisenmenger's Syndrome |
0.0% |
| Hepatitis C |
0.0% |
| Hypertension |
0.0% |
| Cardiac Failure |
0.0% |
| Idiopathic Pulmonary Fibrosis |
0.0% |
|
| Death |
55.5% |
| Pneumonia |
4.7% |
| Dyspnoea |
4.6% |
| Pulmonary Arterial Hypertension |
3.5% |
| Respiratory Failure |
2.8% |
| Right Ventricular Failure |
2.7% |
| Vomiting |
2.7% |
| Syncope |
2.3% |
| Liver Function Test Abnormal |
2.3% |
| Pulmonary Oedema |
2.1% |
| Sepsis |
1.9% |
| Pulmonary Hypertension |
1.9% |
| Pregnancy |
1.8% |
| Oedema Peripheral |
1.7% |
| Myocardial Infarction |
1.6% |
| Urinary Tract Infection |
1.6% |
| Pyrexia |
1.6% |
| Renal Failure |
1.6% |
| Cerebrovascular Accident |
1.5% |
| Fall |
1.5% |
|
| Secondary |
| Pulmonary Arterial Hypertension |
77.9% |
| Pulmonary Hypertension |
10.2% |
| Skin Ulcer |
2.8% |
| Product Used For Unknown Indication |
1.9% |
| Drug Use For Unknown Indication |
1.9% |
| Digital Ulcer |
0.6% |
| Scleroderma |
0.6% |
| Thrombosis Prophylaxis |
0.5% |
| Cardiac Failure |
0.5% |
| Right Ventricular Failure |
0.5% |
| Respiratory Tract Infection |
0.4% |
| Systemic Sclerosis |
0.4% |
| Scleroderma Renal Crisis |
0.3% |
| Nausea |
0.2% |
| Raynaud's Phenomenon |
0.2% |
| Cor Pulmonale Chronic |
0.2% |
| Hiv Infection |
0.2% |
| Shunt Occlusion |
0.2% |
| Anaemia |
0.2% |
| Chronic Obstructive Pulmonary Disease |
0.2% |
|
| Death |
12.8% |
| Dyspnoea |
8.4% |
| Liver Function Test Abnormal |
7.3% |
| Pulmonary Arterial Hypertension |
6.8% |
| Pneumonia |
6.4% |
| Vomiting |
6.2% |
| Right Ventricular Failure |
5.5% |
| Syncope |
4.7% |
| Alanine Aminotransferase Increased |
4.3% |
| Oedema Peripheral |
4.3% |
| Hepatic Function Abnormal |
4.1% |
| Aspartate Aminotransferase Increased |
4.0% |
| Weight Increased |
3.7% |
| Respiratory Failure |
3.6% |
| Transfusion |
3.6% |
| Pyrexia |
3.4% |
| Condition Aggravated |
3.0% |
| Blood Alkaline Phosphatase Increased |
2.7% |
| Haemoptysis |
2.6% |
| Oedema |
2.6% |
|
| Concomitant |
| Pulmonary Arterial Hypertension |
44.0% |
| Pulmonary Hypertension |
25.7% |
| Product Used For Unknown Indication |
6.3% |
| Cor Pulmonale Chronic |
4.3% |
| Drug Use For Unknown Indication |
4.0% |
| Cardiac Failure |
2.0% |
| Prophylaxis |
1.7% |
| Scleroderma |
1.6% |
| Hypertension |
1.5% |
| Rheumatoid Arthritis |
1.3% |
| Pain |
0.9% |
| Gastrooesophageal Reflux Disease |
0.9% |
| Anaemia |
0.8% |
| Asthma |
0.8% |
| Chronic Obstructive Pulmonary Disease |
0.8% |
| Emphysema |
0.8% |
| Oedema |
0.7% |
| Osteoporosis |
0.7% |
| Pneumonia |
0.6% |
| Hypopituitarism |
0.6% |
|
| Death |
26.1% |
| Pneumonia |
10.3% |
| Dyspnoea |
7.9% |
| Pulmonary Hypertension |
7.8% |
| Vomiting |
5.8% |
| Right Ventricular Failure |
4.6% |
| Pulmonary Arterial Hypertension |
4.0% |
| Syncope |
3.9% |
| Respiratory Failure |
3.4% |
| Cardiac Failure |
2.9% |
| Headache |
2.9% |
| Malaise |
2.8% |
| Sepsis |
2.6% |
| Weight Increased |
2.5% |
| Throat Irritation |
2.3% |
| Weight Decreased |
2.2% |
| Dizziness |
2.1% |
| Epistaxis |
2.0% |
| Fluid Retention |
2.0% |
| Nausea |
2.0% |
|
| Interacting |
| Pulmonary Arterial Hypertension |
30.4% |
| Pulmonary Hypertension |
22.6% |
| Bronchopulmonary Aspergillosis |
5.2% |
| Product Used For Unknown Indication |
5.2% |
| Skin Ulcer |
5.2% |
| Aspergillosis |
2.6% |
| Cardiac Failure |
2.6% |
| Coronary Artery Disease |
2.6% |
| Diabetes Mellitus |
2.6% |
| Hepatitis C |
2.6% |
| Hyperthyroidism |
2.6% |
| Pulmonary Embolism |
2.6% |
| Scleroderma |
2.6% |
| Systemic Sclerosis |
2.6% |
| Contraception |
1.7% |
| Helicobacter Infection |
1.7% |
| Hiv Infection |
1.7% |
| Diarrhoea |
0.9% |
| Digital Ulcer |
0.9% |
| Dry Eye |
0.9% |
|
| Drug Level Decreased |
10.9% |
| Vomiting |
9.1% |
| Drug Interaction |
7.3% |
| Abdominal Distension |
5.5% |
| Bilirubin Conjugated Increased |
5.5% |
| Dizziness |
5.5% |
| Hepatic Cirrhosis |
5.5% |
| Hepatic Fibrosis |
5.5% |
| Hepatocellular Injury |
5.5% |
| Blood Amylase Increased |
3.6% |
| Blood Creatinine Increased |
3.6% |
| C-reactive Protein Increased |
3.6% |
| Cardiovascular Disorder |
3.6% |
| Generalised Oedema |
3.6% |
| Hepatitis |
3.6% |
| Hypersensitivity |
3.6% |
| International Normalised Ratio Increased |
3.6% |
| Oedema |
3.6% |
| Thrombocytopenia |
3.6% |
| Unintended Pregnancy |
3.6% |
|
