Epoprostenol Sodium combined with Tracleer

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Liver Function Test Abnormal Other Serious 3/10/2005 17 Female 4/10/2006 Japan
Primary
Concomitant
Nausea Other Serious 8/17/2005 33 Female 97 lb 5/31/2006 Japan
Primary
Concomitant
Weight Increased Other Serious 6/28/2005 57 Female 77 lb 7/10/2006 Physician Japan
Primary
Concomitant
Subileus Hospitalization 4/27/2006 53 Female 90 lb 8/23/2006 Japan
Primary
Concomitant
Vomiting Other Serious 7/1/2006 44 Female 8/29/2006 Physician Japan
Primary
Concomitant
Vomiting Other Serious 3/27/2006 44 Female 99 lb 9/19/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Hypertension Death 12/26/2005 82 Female 11/30/2006 Physician Japan
Primary
Concomitant
Pulmonary Vein Stenosis Hospitalization 4/2/2006 53 Female 100 lb 11/30/2006 Physician Japan
Primary
Secondary
Concomitant
Subileus Hospitalization 4/27/2006 54 Female 90 lb 12/6/2006 Japan
Primary
Concomitant
Venous Pressure Jugular Increased Other Serious 3/20/2006 67 Female 1/3/2007 Physician United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 10/2/2006 47 Female 117 lb 1/22/2007 Japan
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 4/27/2006 54 Female 90 lb 2/21/2007 Japan
Primary
Concomitant
Pulmonary Hypertension Life Threatening 9/10/2005 72 Female 112 lb 3/20/2007 Physician Japan
Primary
Concomitant
Pulmonary Hypertension Life Threatening 9/10/2005 72 Female 112 lb 3/27/2007 Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 3/3/2007 46 Female 5/24/2007 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 11/25/2006 42 Female 148 lb 5/24/2007 Other Health Professional Japan
Primary
Concomitant
Breast Mass Other Serious 6/1/2007 40 Female 121 lb 7/19/2007 Physician United States
Primary
Concomitant
Right Ventricular Failure Other Serious 11/18/2007 75 Female 134 lb 1/4/2008 Physician Netherlands
Primary
Concomitant
Right Ventricular Failure Other Serious 7/18/2006 31 Female 1/5/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/5/2006 42 Female 90 lb 1/21/2008 Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 2/26/2007 43 Female 77 lb 3/11/2008 Physician Japan
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/5/2006 42 Female 90 lb 3/19/2008 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization Female 7/7/2008 Physician Japan
Primary
Concomitant
Liver Function Test Abnormal Other Serious 2/1/2008 61 Male 7/30/2008 Consumer Japan
Primary
Secondary
Liver Function Test Abnormal Other Serious 2/1/2008 61 Male 7/30/2008 Japan
Primary
Secondary
Pulmonary Haemorrhage Hospitalization 9/10/2007 32 Female 123 lb 10/31/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/26/2007 43 Female 77 lb 10/31/2008 Physician Japan
Primary
Concomitant
Shock Other Serious 11/29/2006 25 Male 11/4/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 6/9/2006 23 Male 121 lb 11/3/2008 Physician Japan
Primary
Secondary
Concomitant
Respiratory Tract Haemorrhage Other Serious 24 Female 11/5/2008 Japan
Primary
Concomitant
Vocal Cord Paralysis Hospitalization 34 Female 11/20/2008 Consumer Japan
Primary
Concomitant
Shock Other Serious 11/29/2006 25 Male 11/20/2008 Consumer Japan
Primary
Concomitant
Vocal Cord Paralysis Other Serious 34 Female 12/3/2008 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 3/15/2006 7 Male 40 lb 12/11/2008 Physician Japan
Primary
Concomitant
Operative Haemorrhage Death 10/5/2008 48 Female 110 lb 12/19/2008 Physician Netherlands
Primary
Concomitant
Blood Bilirubin Increased Hospitalization 1/16/2009 30 Female 2/11/2009 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 3/15/2006 7 Male 40 lb 2/20/2009 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 17 Male 3/6/2009 Other Health Professional Japan
Primary
Concomitant
Hepatosplenomegaly Other Serious 1/16/2009 30 Female 95 lb 3/23/2009 Physician Japan
Primary
Concomitant
Ileus Death Male 7/28/2009 Other Health Professional Japan
Primary
Concomitant
Vomiting Other Serious 6/1/2009 39 Female 8/3/2009 Physician United States
Primary
Concomitant
Swelling Other Serious 5/26/2009 26 Female 131 lb 8/7/2009 Pharmacist United States
Primary
Secondary
Concomitant
Organ Transplant Other Serious 60 Female 130 lb 11/30/2009 Other Health Professional Belgium
Primary
Concomitant
Sudden Death Death 41 Male 12/3/2009 France
Primary
Concomitant
Pulmonary Arterial Hypertension Other Serious 10/31/2003 60 Female 130 lb 12/11/2009 Other Health Professional Belgium
Primary
Concomitant
Pulmonary Haemorrhage Hospitalization 10/23/2008 24 Female 99 lb 12/17/2009 Japan
Primary
Concomitant
Right Ventricular Failure Other Serious 6/27/2008 1 Male 4/12/2010 Japan
Primary
Concomitant
Ventricular Septal Defect Other Serious 5/26/2008 1 Male 9 lb 4/30/2010 Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/23/2010 39 Female 101 lb 6/8/2010 Japan
Primary
Concomitant
Vomiting Other Serious 1/1/2004 72 Female 8/6/2010 Physician United States
Primary
Secondary
Concomitant
Haemoptysis Death 21 Female 8/10/2010 Physician Japan
Primary
Concomitant
Haemoptysis Death 21 Female 8/27/2010 Physician Japan
Primary
Concomitant
International Normalised Ratio Decreased Hospitalization 7/4/2005 42 Female 108 lb 9/7/2010 Japan
Primary
Secondary
Concomitant
No Adverse Event 39 Female 101 lb 9/8/2010 Japan
Primary
Concomitant
Torsade De Pointes Life Threatening 9/10/2010 Female 9/20/2010 Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 9/9/2010 23 Female 75 lb 10/5/2010 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 9/9/2010 23 Female 75 lb 10/18/2010 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 9/9/2010 23 Female 75 lb 11/8/2010 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Other Serious 0 Male 11/16/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 11/7/2010 11/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Device Malfunction Hospitalization 8/4/2010 43 Female 10/19/2010 Physician United States
Primary
Concomitant
Pancreatic Carcinoma Metastatic Death 77 Female 11/23/2010 Physician Japan
Primary
Concomitant
Death Death 5/1/2003 52 Female 12/6/2010 Consumer Italy
Primary
Concomitant
White Blood Cell Count Decreased Death 1/1/2009 44 Female 12/6/2010 Physician Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 10/24/2005 54 Female 115 lb 12/6/2010 Physician Japan
Primary
Secondary
Concomitant
Death Death 9/3/2010 66 Female 12/9/2010 Pharmacist United States
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 7/4/2005 42 Female 108 lb 12/16/2010 Physician Japan
Primary
Secondary
Concomitant
Catheter Site Pruritus Other Serious 36 Female 1/4/2011 Physician Japan
Primary
Secondary
Concomitant
Packed Red Blood Cell Transfusion Hospitalization 1/1/2009 1/15/2011 Physician United States
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 1/11/2010 33 Female 2/7/2011 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/30/2011 2/13/2011 Pharmacist United States
Primary
Concomitant
Diarrhoea Haemorrhagic Hospitalization 12/22/2010 64 Male 230 lb 1/25/2011 Physician United States
Primary
Concomitant
Death Death 12/1/2010 Female 1/23/2011 Physician United States
Primary
Concomitant
Lung Infiltration Other Serious 12/1/2010 13 Female 1/21/2011 Physician United States
Primary
Secondary
Vomiting Required Intervention 1/1/2009 57 Female 143 lb 1/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Life Threatening 9/9/2010 23 Female 75 lb 3/16/2011 Physician Japan
Primary
Secondary
Concomitant
Fatigue Life Threatening 3/1/2009 43 Female 3/16/2011 Physician Japan
Primary
Concomitant
Pulmonary Arterial Hypertension Death 59 Female 3/21/2011 Physician Israel
Primary
Concomitant
Asthenia Hospitalization 1/31/2011 37 Female 3/11/2011 Pharmacist United States
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 5/1/2010 75 Male 3/25/2011 Physician Japan
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 3/6/2011 4/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Hospitalization 11/18/2009 20 Female 110 lb 4/11/2011 Physician Japan
Primary
Secondary
Concomitant
Pericardial Effusion Death 3/15/2006 7 Male 40 lb 4/12/2011 Physician Japan
Primary
Secondary
Concomitant
Isolated Adrenocorticotropic Hormone Deficiency Life Threatening 3/1/2009 43 Female 4/21/2011 Physician Japan
Primary
Concomitant
Chills Death 3/6/2011 4/29/2011 Physician United States
Primary
Secondary
Concomitant
Nausea Death 5/1/2011 5/6/2011 Pharmacist United States
Primary
Concomitant
Death Death 5/3/2011 5/9/2011 Physician United States
Primary
Secondary
Concomitant
Death Death 5/4/2011 5/9/2011 Pharmacist United States
Primary
Secondary
Blood Potassium Decreased Life Threatening 3/1/2010 5/10/2011 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Death 5/4/2011 5/13/2011 Pharmacist United States
Primary
Secondary
Nausea Death 5/2/2011 5/13/2011 Physician United States
Primary
Secondary
Death Death 5/9/2011 5/14/2011 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 35 Female 5/16/2011 Physician Germany
Primary
Concomitant
Dysarthria Death 5/8/2011 5/17/2011 Pharmacist United States
Primary
Secondary
Concomitant
Death Death 5/11/2011 5/17/2011 Physician United States
Primary
Secondary
Concomitant
Death Death 5/11/2011 5/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Viith Nerve Paralysis Hospitalization 4/30/2011 5/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Abdominal Pain Upper Hospitalization 3/6/2011 5/25/2011 Other Health Professional United States
Primary
Concomitant
Disease Progression Death 4/12/2011 5/26/2011 Pharmacist United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 3/30/2011 5/31/2011 Consumer United States
Primary
Concomitant
Nausea Hospitalization 4/16/2011 5/31/2011 Pharmacist United States
Primary
Secondary
Nausea Death 5/2/2011 6/1/2011 Consumer United States
Primary
Secondary
Concomitant Disease Aggravated Death 10/1/2010 77 Female 6/2/2011 Physician Japan
Primary
Concomitant
Diarrhoea Hospitalization 3/6/2011 6/2/2011 Physician United States
Primary
Secondary
Concomitant
Resuscitation Hospitalization 3/6/2011 6/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Disease Progression Hospitalization 2/18/2011 6/6/2011 Pharmacist United States
Primary
Secondary
Pneumonia Hospitalization 5/8/2011 6/7/2011 Pharmacist United States
Primary
Concomitant
Haemoptysis Hospitalization 5/1/2011 6/10/2011 Pharmacist United States
Primary
Secondary
Concomitant
Autoimmune Disorder Hospitalization 3/23/2011 6/13/2011 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Hospitalization 5/11/2011 6/13/2011 Pharmacist United States
Primary
Concomitant
Diarrhoea Hospitalization 3/6/2011 6/15/2011 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/6/2011 6/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Road Traffic Accident Death 3/18/2011 31 Male 6/16/2011 Physician Japan
Primary
Concomitant
Blood Bilirubin Increased Other Serious 1/1/2011 6/20/2011 Pharmacist United States
Primary
Secondary
Concomitant
Anaemia Death 12/25/2007 22 Female 106 lb 6/21/2011 Physician Japan
Primary
Secondary
Concomitant
Dyspnoea Death 4/15/2011 6/29/2011 Pharmacist United States
Primary
Secondary
Concomitant
Cardiac Disorder Hospitalization 6/17/2011 6/29/2011 Pharmacist United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 1/1/2011 8/2/2011 Consumer United States
Primary
Secondary
Concomitant
Pain Hospitalization 7/1/2011 8/9/2011 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 1/1/2011 8/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 8/3/2011 8/16/2011 Physician United States
Primary
Concomitant
Blood Potassium Increased Hospitalization 8/1/2011 8/16/2011 Physician United States
Primary
Concomitant
Condition Aggravated Death 1/1/2011 8/19/2011 Consumer United States
Primary
Secondary
Concomitant
Death Hospitalization 7/21/2011 8/26/2011 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Arterial Hypertension Life Threatening 7/21/2011 9/6/2011 Physician United States
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 9/9/2010 23 Female 75 lb 9/7/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/1/2011 9/7/2011 Pharmacist United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 8/3/2011 9/8/2011 Other Health Professional United States
Primary
Concomitant
Breast Cancer Other Serious 7/1/2011 9/8/2011 Pharmacist United States
Primary
Concomitant
Death Death 9/1/2011 9/8/2011 Pharmacist United States
Primary
Concomitant
Device Related Infection Hospitalization 9/3/2011 9/12/2011 Physician United States
Primary
Secondary
Concomitant
Death Death 9/1/2011 9/12/2011 Other Health Professional United States
Primary
Secondary
Diarrhoea Hospitalization 9/1/2011 9/15/2011 Physician United States
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 8/3/2011 9/16/2011 Other Health Professional United States
Primary
Secondary
Right Ventricular Failure Hospitalization 8/3/2011 9/16/2011 Other Health Professional United States
Primary
Secondary
Device Related Infection Hospitalization 9/3/2011 9/22/2011 Physician United States
Primary
Secondary
Concomitant
Skin Discolouration 7/1/2011 9/22/2011 Pharmacist United States
Primary
Concomitant
Diarrhoea Hospitalization 9/1/2011 9/22/2011 Pharmacist United States
Primary
Secondary
Concomitant
Death Hospitalization 9/1/2011 9/27/2011 Physician United States
Primary
Secondary
Concomitant
Mental Disorder Hospitalization 6/1/2011 9/29/2011 Pharmacist United States
Primary
Secondary
Concomitant
Infection Hospitalization 9/1/2011 9/29/2011 Physician United States
Primary
Concomitant
Device Damage Hospitalization 9/1/2011 10/4/2011 Physician United States
Primary
Secondary
Concomitant
Right Ventricular Failure Death 8/3/2011 10/4/2011 Pharmacist United States
Primary
Secondary
Food Poisoning Hospitalization 4/16/2011 10/11/2011 Physician United States
Primary
Secondary
Concomitant
Medical Device Complication Hospitalization 8/23/2011 10/12/2011 Physician United States
Primary
Secondary
Concomitant
Mental Disorder Hospitalization 6/1/2011 10/12/2011 Pharmacist United States
Primary
Secondary
Concomitant
Transfusion Hospitalization 9/21/2011 10/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 1/1/2011 22 Male 130 lb 10/17/2011 Physician United States
Primary
Concomitant
Diarrhoea Hospitalization 4/16/2011 10/18/2011 Pharmacist United States
Primary
Secondary
Concomitant
Panic Attack Hospitalization 10/1/2011 10/19/2011 Physician United States
Primary
Concomitant

Drug Data