Spironolactone combined with Tracleer

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Liver Function Test Abnormal Other Serious 3/21/2005 65 Female 106 lb 1/13/2006 Netherlands
Primary
Concomitant
Platelet Count Decreased Other Serious 11/4/2005 72 Female 97 lb 1/18/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 1/7/2005 59 Male 1/18/2006 Sweden
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 9/1/2005 74 Female 1/23/2006 Physician Germany
Primary
Concomitant
Malaise Other Serious 8/20/2005 17 Female 108 lb 1/21/2006 Physician Japan
Primary
Concomitant
Rash Papular Hospitalization 9/16/2005 59 Female 105 lb 1/25/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 33 Female 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Required Intervention 3/1/2005 49 Female 2/1/2006 Physician United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Required Intervention 11/24/2005 89 Female 129 lb 2/1/2006 Germany
Primary
Concomitant
Nausea Other Serious 11/1/2005 38 Female 2/1/2006 Physician Israel
Primary
Concomitant
Malaise Hospitalization 11/17/2005 59 Female 106 lb 2/8/2006 Physician Japan
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 9/5/2005 52 Female 101 lb 2/9/2006 Physician Japan
Primary
Concomitant
Vomiting Other Serious 1/24/2006 76 Female 2/13/2006 Physician Japan
Primary
Concomitant
Shock Other Serious 11/4/2005 72 Female 97 lb 2/23/2006 Physician Japan
Primary
Secondary
Concomitant
Vein Disorder Other Serious 9/7/2005 20 Female 121 lb 2/27/2006 Physician United States
Primary
Concomitant
Nausea Other Serious 11/1/2005 38 Female 3/3/2006 Physician Israel
Primary
Concomitant
Vomiting Other Serious 1/24/2006 76 Female 3/9/2006 Physician Japan
Primary
Concomitant
Somnolence Hospitalization 11/17/2005 59 Female 99 lb 3/14/2006 Physician Japan
Primary
Secondary
Concomitant
Death Death 1/19/2005 64 Male 143 lb 3/23/2006 Other Health Professional Netherlands
Primary
Concomitant
Vomiting Other Serious 1/24/2006 76 Female 3/24/2006 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 12/1/2005 1 Female 4/3/2006 Pharmacist Ireland
Primary
Concomitant
Platelet Count Decreased Other Serious 12/1/2005 1 Female 4/12/2006 Pharmacist Ireland
Primary
Concomitant
Therapy Non-responder Hospitalization 11/16/2005 29 Male 4/19/2006 Physician Australia
Primary
Concomitant
Pneumonia Hospitalization 12/30/2004 59 Male 4/20/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Palpitations Other Serious 2/26/2006 17 Female 87 lb 4/24/2006 Japan
Primary
Concomitant
Liver Function Test Abnormal Required Intervention 3/23/2006 71 Male 146 lb 4/26/2006 Other Health Professional Netherlands
Primary
Concomitant
Platelet Count Decreased Other Serious 12/1/2005 1 Female 4/26/2006 Pharmacist Ireland
Primary
Concomitant
Drug Interaction Other Serious 6/24/2005 68 Female 187 lb 5/9/2006 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 2/26/2006 17 Female 87 lb 5/10/2006 Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 12/1/2005 1 Female 5/18/2006 Pharmacist Ireland
Primary
Concomitant
Hepatic Function Abnormal Other Serious 3/23/2006 71 Male 146 lb 5/18/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 3/25/2006 47 Female 123 lb 5/19/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 9/5/2005 52 Female 101 lb 5/25/2006 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 3/23/2006 71 Male 146 lb 5/25/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Malaise Hospitalization 11/17/2005 59 Female 99 lb 5/25/2006 Physician Japan
Primary
Secondary
Concomitant
Nausea Other Serious 8/17/2005 33 Female 97 lb 5/31/2006 Japan
Primary
Concomitant
Right Ventricular Failure Other Serious 3/25/2006 53 Female 123 lb 6/2/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting 1/19/2006 54 Female 120 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Pharyngolaryngeal Pain 40 Female 136 lb 4/25/2006 Other Health Professional United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 3/22/2005 57 Female 143 lb 6/23/2006 Belgium
Primary
Concomitant
Obliterative Bronchiolitis Hospitalization 5/5/2006 77 Female 101 lb 6/27/2006 Physician Japan
Primary
Concomitant
Rash Generalised Hospitalization 9/16/2005 59 Female 105 lb 6/30/2006 Physician Japan
Primary
Concomitant
Liver Function Test Abnormal Other Serious 3/23/2006 71 Male 146 lb 7/5/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/21/2006 47 Female 155 lb 7/5/2006 Physician United States
Primary
Secondary
Concomitant
Asthma Hospitalization 10/6/2005 31 Female 7/18/2006 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 6/24/2006 71 Female 146 lb 7/20/2006 Netherlands
Primary
Concomitant
Pregnancy Other Serious 10/1/2005 23 Female 7/20/2006 Physician United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 2/26/2006 17 Female 87 lb 7/25/2006 Japan
Primary
Concomitant
Vomiting Hospitalization 1/1/2006 54 Female 90 lb 7/26/2006 Physician France
Primary
Concomitant
Po2 Decreased Hospitalization 5/5/2006 77 Female 101 lb 7/27/2006 Japan
Primary
Concomitant
Vomiting Other Serious 5/9/2006 48 Female 121 lb 8/7/2006 Physician Netherlands
Primary
Concomitant
Vomiting Hospitalization 1/1/2006 54 Female 90 lb 8/11/2006 Physician France
Primary
Concomitant
Oedema Hospitalization 1/31/2006 37 Female 8/17/2006 Germany
Primary
Concomitant
White Blood Cell Count Increased Required Intervention 3/1/2005 63 Female 8/17/2006 Physician United States
Primary
Concomitant
Subileus Hospitalization 4/27/2006 53 Female 90 lb 8/23/2006 Japan
Primary
Concomitant
Tremor 49 Female 160 lb 7/24/2006 Other Health Professional United States
Primary
Concomitant
Pain In Jaw 44 Female 138 lb 7/25/2006 Other Health Professional United States
Primary
Concomitant
Haemoptysis 71 Female 136 lb 7/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain 40 Female 136 lb 7/24/2006 Other Health Professional United States
Primary
Concomitant
Nausea 59 Female 155 lb 7/24/2006 Other Health Professional United States
Primary
Concomitant
Somnolence 47 Male 253 lb 7/24/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 54 Female 90 lb 9/1/2006 France
Primary
Concomitant
Vomiting Other Serious 54 Female 90 lb 9/1/2006 France
Primary
Concomitant
Pulmonary Hypertension Hospitalization 1/31/2006 37 Female 9/6/2006 Physician Germany
Primary
Concomitant
Respiratory Failure Hospitalization 7/4/2006 58 Female 155 lb 9/12/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 3/25/2006 53 Female 123 lb 9/18/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 54 Female 90 lb 9/19/2006 France
Primary
Concomitant
Vomiting Other Serious 54 Female 90 lb 9/25/2006 Physician France
Primary
Concomitant
Pneumonia Other Serious 8/29/2006 18 Female 130 lb 9/25/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/21/2006 11 Male 77 lb 10/5/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 8/18/2006 77 Female 213 lb 10/5/2006 United States
Primary
Concomitant
Pneumonia Hospitalization 8/24/2006 18 Female 130 lb 10/18/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Required Intervention 8/27/2005 43 Female 10/18/2006 United States
Primary
Concomitant
Wound Infection Other Serious 3/1/2006 60 Female 105 lb 10/30/2006 Physician United States
Primary
Concomitant
Subileus Hospitalization 4/27/2006 54 Female 90 lb 12/6/2006 Japan
Primary
Concomitant
Weight Increased Other Serious 11/5/2006 19 Male 12/7/2006 Japan
Primary
Concomitant
Right Ventricular Failure Death 10/27/2004 58 Female 12/15/2006 Physician United States
Primary
Concomitant
Right Ventricular Failure Other Serious 6/30/2006 63 Male 121 lb 12/18/2006 Physician Japan
Primary
Secondary
Concomitant
Polymyalgia Rheumatica Required Intervention 7/1/2006 59 Female 159 lb 12/18/2006 Other Health Professional Netherlands
Primary
Concomitant
Respiratory Failure Hospitalization 11/18/2006 62 Male 187 lb 12/18/2006 Physician Spain
Primary
Secondary
Urine Output Decreased Hospitalization 11/18/2006 62 Male 187 lb 1/3/2007 Physician Spain
Primary
Secondary
Paraesthesia Oral 71 Female 136 lb 10/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Dry Throat 1/1/2006 47 Female 130 lb 10/24/2006 United States
Primary
Concomitant
Pain In Extremity 1/1/2006 66 Female 162 lb 10/24/2006 Pharmacist United States
Primary
Concomitant
Speech Disorder 1/1/2005 64 Male 276 lb 10/24/2006 Other Health Professional United States
Primary
Concomitant
Oral Mucosal Blistering 1/1/2005 54 Female 164 lb 10/24/2006 Other Health Professional United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 11/6/2006 36 Male 128 lb 1/9/2007 Physician Japan
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 11/20/2006 48 Female 86 lb 1/11/2007 Japan
Primary
Concomitant
Stent Placement Other Serious 10/1/2006 70 Male 1/31/2007 Physician United States
Primary
Concomitant
Right Ventricular Failure Life Threatening 1/19/2006 33 Female 108 lb 2/9/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Required Intervention 11/28/2005 68 Female 2/9/2007 Physician United States
Primary
Concomitant
Polymyalgia Rheumatica Required Intervention 7/1/2006 59 Female 159 lb 2/21/2007 Other Health Professional Netherlands
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 4/27/2006 54 Female 90 lb 2/21/2007 Japan
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Life Threatening 10/19/2006 54 Female 2/21/2007 Japan
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 1/19/2006 39 Female 3/8/2007 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 11/18/2006 62 NotSpecified 187 lb 3/6/2007 Physician Spain
Primary
Secondary
Vomiting Required Intervention 6/23/2005 36 Female 90 lb 3/20/2007 Physician Japan
Primary
Secondary
Concomitant
Urticaria 9/1/2006 28 Female 200 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Drooling 7/27/2006 18 Male 84 lb 1/23/2007 Consumer United States
Primary
Concomitant
Pulmonary Hypertension 3/1/2006 65 Female 152 lb 1/23/2007 Consumer United States
Primary
Concomitant
Palpitations 37 Female 224 lb 1/23/2007 Consumer United States
Primary
Concomitant
Sensation Of Foreign Body 11/1/2005 47 Female 165 lb 1/23/2007 Consumer United States
Primary
Concomitant
Oral Pain 10/1/2006 58 Female 200 lb 1/23/2007 Consumer United States
Primary
Concomitant
Post Procedural Infection Required Intervention 12/1/2006 70 Female 110 lb 5/1/2007 Physician United States
Primary
Concomitant
Infection Life Threatening 9/9/2004 31 Female 110 lb 5/15/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening 9/9/2004 31 Female 110 lb 5/21/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/25/2006 42 Female 148 lb 5/24/2007 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Death 3/14/2007 79 Female 5/24/2007 Sweden
Primary
Concomitant
Vomiting Required Intervention 6/23/2005 36 Female 90 lb 6/4/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 3/25/2006 Female 115 lb 6/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemoptysis Other Serious 4/4/2007 70 Female 132 lb 7/25/2007 Physician Netherlands
Primary
Concomitant
Bacterial Infection Required Intervention 2/1/2007 46 Male 128 lb 7/10/2007 Other Health Professional United States
Primary
Concomitant
Erythema Multiforme Hospitalization 5/1/2007 81 Female 8/23/2007 Japan
Primary
Concomitant
Pneumonia Hospitalization 10/30/2004 30 Female 8/31/2007 Physician Japan
Primary
Concomitant
Pain In Jaw Other Serious 7/1/2006 66 Female 162 lb 9/12/2007 Physician United States
Primary
Secondary
Concomitant
Metastases To Bone Hospitalization 8/27/2007 56 Female 128 lb 9/7/2007 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 3/29/2007 69 Male 135 lb 9/21/2007 Other Health Professional Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 7/4/2005 42 Female 108 lb 9/21/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Breast Cancer Recurrent Hospitalization 8/27/2007 56 Female 128 lb 9/20/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/24/2005 54 Female 115 lb 10/11/2007 Japan
Primary
Concomitant
Breast Cancer Recurrent Hospitalization 8/27/2007 Female 128 lb 10/25/2007 Physician Japan
Primary
Concomitant
Thyroid Disorder Hospitalization 4/1/2006 15 Female 11/13/2007 Physician Japan
Primary
Concomitant
Sepsis Other Serious 8/20/2005 17 Female 11/14/2007 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Death 10/26/2007 42 Female 11/14/2007 Physician Netherlands
Primary
Concomitant
Dyspnoea Death 1/1/2007 65 Female 86 lb 11/14/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/4/2006 58 Female 95 lb 11/14/2007 Physician Japan
Primary
Secondary
Concomitant
Sudden Cardiac Death Hospitalization 9/16/2005 59 Female 105 lb 11/19/2007 Physician Japan
Primary
Concomitant
Mania Other Serious 11/21/2007 77 Female 12/7/2007 Pharmacist United Kingdom
Primary
Concomitant
Dyspnoea Death 1/1/2007 65 Female 86 lb 12/11/2007 Physician Japan
Primary
Concomitant
Mania Required Intervention 11/21/2007 77 Female 12/14/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Dizziness Hospitalization 9/12/2007 33 Female 119 lb 12/19/2007 Consumer Japan
Primary
Secondary
Concomitant
Palpitations Hospitalization 6/18/2007 64 Female 171 lb 12/19/2007 Physician United States
Primary
Concomitant
Anaemia Other Serious 70 Male 12/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/28/2007 26 Female 115 lb 12/22/2007 Germany
Primary
Concomitant
Anaemia Other Serious 70 Male 12/21/2007 United Kingdom
Primary
Secondary
Concomitant
Thyroid Disorder Hospitalization 4/1/2006 15 Female 1/8/2008 Physician Japan
Primary
Concomitant
Anaemia Other Serious 70 Male 12/21/2007 United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 8/20/2005 17 Female 1/9/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 10/10/2007 68 Female 1/21/2008 United Kingdom
Primary
Concomitant
Infection Other Serious 11/28/2007 26 Female 115 lb 1/21/2008 Germany
Primary
Concomitant
Cardiac Failure Acute Death 75 Female 1/23/2008 Physician Netherlands
Primary
Concomitant
Mania Required Intervention 11/21/2007 77 Female 106 lb 2/1/2008 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Wrong Drug Administered Hospitalization 11/20/2007 72 Female 116 lb 2/11/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/4/2007 44 Female 2/15/2008 Physician United States
Primary
Concomitant
Wrong Drug Administered Hospitalization 11/20/2007 72 Female 138 lb 2/11/2008 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 11/4/2006 58 Female 95 lb 2/11/2008 Japan
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 1/4/2008 44 Female 2/16/2008 Sweden
Primary
Concomitant
Right Ventricular Failure Other Serious 1/4/2008 44 Female 2/22/2008 Sweden
Primary
Concomitant
Breast Cancer Recurrent Hospitalization 8/27/2007 Female 128 lb 2/27/2008 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 10/4/2007 44 Female 3/5/2008 Physician United States
Primary
Concomitant

Drug Data