Topotecan



Combined with:

Indications and Reactions:

Role Indications Reactions
Primary
Ovarian Cancer 18.7%
Neoplasm 9.4%
Hypertension 9.0%
Neuroblastoma 7.4%
Ovarian Cancer Recurrent 7.4%
Pain 7.3%
Prophylaxis 4.9%
Small Cell Lung Cancer Stage Unspecified 4.8%
Vestibular Neuronitis 4.7%
Nausea 4.5%
Cervix Carcinoma 4.0%
Neoplasm Malignant 2.9%
Drug Use For Unknown Indication 2.6%
Constipation 2.5%
Glioblastoma 2.0%
Vomiting 1.9%
Non-small Cell Lung Cancer 1.7%
Urinary Tract Infection 1.6%
Anxiety 1.5%
Atrial Fibrillation 1.4%
Vomiting 18.5%
Thrombocytopenia 17.6%
Pyrexia 9.6%
Febrile Bone Marrow Aplasia 7.5%
White Blood Cell Count Decreased 5.4%
Respiratory Failure 3.9%
Dehydration 3.6%
Dyspnoea 3.3%
Ileus 3.3%
Urinary Tract Infection 3.0%
Nausea 2.7%
Pain 2.7%
Pneumonia 2.7%
Weight Decreased 2.7%
Dizziness 2.4%
Lethargy 2.4%
Muscular Weakness 2.4%
Rash 2.4%
General Physical Health Deterioration 2.1%
Neutropenia 2.1%
Secondary
Ovarian Cancer 17.0%
Colorectal Cancer 15.8%
Neuroblastoma 11.5%
Drug Use For Unknown Indication 8.1%
Prophylaxis 7.0%
Acute Myeloid Leukaemia 5.7%
Glioblastoma 4.6%
Squamous Cell Carcinoma Of The Cervix 4.2%
Acute Lymphocytic Leukaemia 3.4%
Ewing's Sarcoma 3.4%
Product Used For Unknown Indication 3.1%
Premedication 2.1%
Alveolar Rhabdomyosarcoma 2.0%
Hypertension 2.0%
Vomiting 1.9%
Chemotherapy 1.8%
Colon Cancer Metastatic 1.8%
Colon Cancer 1.5%
Neoplasm 1.5%
Ovarian Cancer Recurrent 1.5%
Thrombocytopenia 14.0%
Pulmonary Alveolar Haemorrhage 11.6%
Vomiting 11.6%
White Blood Cell Count Decreased 7.4%
Infection 6.2%
Sepsis 5.8%
Colorectal Cancer 5.0%
Neutropenia 4.1%
Anaemia 3.7%
Diarrhoea 3.7%
Multiple Myeloma 3.3%
Staphylococcal Infection 3.3%
Interstitial Lung Disease 2.9%
Death 2.5%
Febrile Neutropenia 2.5%
Neutrophil Count Decreased 2.5%
Pain 2.5%
Pancreatitis Acute 2.5%
Renal Failure Chronic 2.5%
Respiratory Failure 2.5%
Concomitant
Drug Use For Unknown Indication 18.8%
Ovarian Cancer 12.3%
Product Used For Unknown Indication 9.3%
Ovarian Cancer Recurrent 6.3%
Colorectal Cancer 6.1%
Breast Cancer 4.4%
Prophylaxis 4.3%
Pain 4.1%
Rectal Cancer Metastatic 4.1%
Pancreatic Neuroendocrine Tumour 3.8%
Colon Cancer Metastatic 3.7%
Colon Cancer Recurrent 3.4%
Acute Lymphocytic Leukaemia 3.1%
Hypertension 3.1%
Prophylaxis Of Nausea And Vomiting 3.0%
Rectal Cancer Recurrent 2.8%
Nausea 1.9%
Burkitt's Lymphoma 1.8%
Chemotherapy 1.8%
Multiple Myeloma 1.8%
Renal Failure Chronic 11.1%
Interstitial Lung Disease 7.1%
Thrombocytopenia 7.1%
Urge Incontinence 7.1%
White Blood Cell Count Abnormal 7.1%
Vomiting 6.1%
Disease Progression 5.1%
Pyrexia 5.1%
Thrombosis 5.1%
Congestive Cardiomyopathy 4.0%
Pain 4.0%
Pneumonia 4.0%
Sepsis 4.0%
Septic Shock 4.0%
White Blood Cell Count Decreased 4.0%
Acute Graft Versus Host Disease 3.0%
Bone Marrow Failure 3.0%
Death 3.0%
Haemoglobin Abnormal 3.0%
Melaena 3.0%