Rapamune



Indications and Reactions:

Role Indications Reactions
Primary
Prophylaxis Against Transplant Rejection 58.7%
Renal Transplant 9.3%
Hypertension 6.9%
Immunosuppression 4.4%
Immunosuppressant Drug Therapy 3.8%
Liver Transplant 3.0%
Heart Transplant 1.9%
Diabetes Mellitus 1.8%
Graft Versus Host Disease 1.8%
Prophylaxis 1.7%
Transplant 1.6%
Prophylaxis Against Gastrointestinal Ulcer 1.0%
Anaemia 0.6%
Blood Pressure Abnormal 0.5%
Constipation 0.5%
Lung Transplant 0.5%
Infection Prophylaxis 0.5%
Lymphangioleiomyomatosis 0.5%
Hypercholesterolaemia 0.5%
Kidney Transplant Rejection 0.5%
Death 14.1%
Kidney Transplant Rejection 13.5%
Off Label Use 7.3%
Vomiting 6.2%
Transplant Rejection 5.7%
Venoocclusive Liver Disease 5.4%
Pyrexia 4.5%
Renal Failure 4.4%
Weight Decreased 4.2%
Renal Failure Acute 3.8%
Pneumonitis 3.7%
Liver Transplant Rejection 3.6%
Proteinuria 3.6%
Renal Impairment 3.6%
Thrombocytopenia 3.5%
Pneumonia 2.9%
Thrombotic Microangiopathy 2.7%
Lung Disorder 2.5%
Renal Tubular Necrosis 2.5%
Urinary Tract Infection 2.3%
Secondary
Prophylaxis Against Transplant Rejection 38.1%
Renal Transplant 11.4%
Hypertension 8.8%
Product Used For Unknown Indication 8.6%
Immunosuppression 6.5%
Antiretroviral Therapy 4.4%
Graft Versus Host Disease 3.1%
Drug Use For Unknown Indication 2.7%
Immunosuppressant Drug Therapy 2.7%
Prophylaxis 2.2%
Transplant 1.9%
Diabetes Mellitus 1.4%
Hyperlipidaemia 1.1%
Liver Transplant 1.1%
Prophylaxis Against Renal Transplant Rejection 1.1%
Prophylaxis Against Gastrointestinal Ulcer 1.0%
Blood Pressure Abnormal 1.0%
Hiv Infection 1.0%
Neuroendocrine Carcinoma Of The Skin 1.0%
Thrombosis Prophylaxis 0.9%
Venoocclusive Liver Disease 11.1%
Kidney Transplant Rejection 8.0%
Transplant Rejection 8.0%
Weight Decreased 6.7%
Renal Impairment 6.5%
Vomiting 6.5%
Renal Failure Acute 6.2%
Death 4.9%
Renal Failure 4.9%
Osteonecrosis 4.7%
Pyrexia 4.1%
Thrombocytopenia 4.1%
Liver Transplant Rejection 3.4%
Urine Colour Abnormal 3.4%
Off Label Use 3.1%
Pharyngitis 3.1%
Pneumonitis 3.1%
Premature Baby 3.1%
Staphylococcal Infection 2.6%
Urinary Tract Infection 2.6%
Concomitant
Product Used For Unknown Indication 31.6%
Drug Use For Unknown Indication 23.6%
Prophylaxis Against Transplant Rejection 7.3%
Renal Transplant 5.7%
Hypertension 4.6%
Prophylaxis 3.3%
Pain 2.8%
Immunosuppression 2.6%
Heart Transplant 2.5%
Nuclear Magnetic Resonance Imaging 2.1%
Dialysis 1.8%
Antiviral Prophylaxis 1.7%
Liver Transplant 1.6%
Gastrooesophageal Reflux Disease 1.4%
Diabetes Mellitus 1.3%
Hepatic Neoplasm Malignant 1.3%
Constipation 1.3%
Vitamin Supplementation 1.3%
Anaemia 1.2%
Incision Site Pain 1.0%
Death 17.0%
Renal Impairment 8.3%
Vomiting 7.8%
Pyrexia 7.3%
Urinary Tract Infection 6.3%
Therapeutic Response Decreased 5.3%
Weight Decreased 4.9%
Cerebral Ischaemia 4.4%
Hepatic Neoplasm Malignant 3.9%
Weight Increased 3.9%
Diarrhoea 3.4%
Oedema Peripheral 3.4%
Off Label Use 3.4%
Renal Transplant 3.4%
Hypertension 2.9%
Renal Failure 2.9%
Reticulocyte Count Decreased 2.9%
Skin Hypertrophy 2.9%
Suicidal Ideation 2.9%
Transplant Rejection 2.9%
Interacting
Prophylaxis Against Transplant Rejection 22.1%
Hypertension 11.3%
Immunosuppression 8.7%
Lower Respiratory Tract Infection 8.2%
Immunosuppressant Drug Therapy 5.6%
Hiv Infection 5.1%
Antiretroviral Therapy 4.6%
Hypercholesterolaemia 4.1%
Calcium Deficiency 3.1%
Constipation 3.1%
Hypertriglyceridaemia 3.1%
Renal Transplant 3.1%
Anxiety 2.6%
Depression 2.6%
Drug Use For Unknown Indication 2.6%
Pain 2.6%
Gastric Disorder 2.1%
Prophylaxis 2.1%
Renal Impairment 2.1%
Contraception 1.5%
Renal Impairment 14.6%
Rhabdomyolysis 14.6%
Macular Oedema 12.2%
Fatigue 7.3%
Immunosuppressant Drug Level Increased 7.3%
Pneumonia 7.3%
Transplant Rejection 7.3%
Drug Interaction 4.9%
Lung Disorder 4.9%
Somnolence 4.9%
Drug Level Increased 2.4%
Hepatic Enzyme Increased 2.4%
Hyperglycaemia 2.4%
Proteinuria 2.4%
Renal Failure Acute 2.4%
Thrombocytopenia 2.4%