Cyclosporine combined with Rapamune

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Impairment Other Serious 7/25/2005 30 Female 1/3/2006 Brazil
Primary
Concomitant
Urinary Tract Infection Other Serious 4/18/2005 47 Male 1/4/2006 Brazil
Primary
Concomitant
Scrotal Oedema Other Serious 12/26/2005 39 Male 1/5/2006 Physician Brazil
Primary
Concomitant
Lymphocele Other Serious 11/24/2005 48 Male 1/20/2006 Brazil
Primary
Concomitant
Kidney Transplant Rejection Other Serious 10/26/2005 48 Male 1/26/2006 Brazil
Primary
Concomitant
Proteinuria Other Serious 7/7/2005 50 Female 1/30/2006 Brazil
Primary
Secondary
Concomitant
Proteinuria Other Serious 7/5/2005 50 Female 1/30/2006 Brazil
Primary
Secondary
Concomitant
Ulcer Haemorrhage Hospitalization 1/3/2006 58 Male 2/3/2006 France
Primary
Secondary
Concomitant
Kidney Transplant Rejection Other Serious 6/7/2005 50 Female 2/3/2006 Brazil
Primary
Concomitant
Kidney Transplant Rejection Other Serious 6/7/2005 50 Female 2/7/2006 Brazil
Primary
Concomitant
Colon Cancer Hospitalization 7/8/2005 62 Male 2/16/2006 China
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/11/2005 25 Female 2/24/2006 Consumer United Kingdom
Primary
Secondary
Pyrexia Hospitalization 3/23/2005 60 Female 2/23/2006 Brazil
Primary
Concomitant
Scar Other Serious 59 Male 2/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Kidney Transplant Rejection Other Serious 11/18/2005 26 Male 2/27/2006 Pharmacist Brazil
Primary
Concomitant
Kidney Transplant Rejection Other Serious 7/24/2005 21 Male 2/28/2006 Other Health Professional Brazil
Primary
Concomitant
Vascular Graft Complication Other Serious 1/10/2006 55 Male 3/2/2006 France
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 1/17/2006 52 Male 192 lb 3/10/2006 Pharmacist United States
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization 1/10/2006 39 Male 3/7/2006 Brazil
Primary
Concomitant
Pyrexia Hospitalization 11/11/2005 26 Male 3/14/2006 Brazil
Primary
Concomitant
Pyrexia Hospitalization 11/11/2005 26 Male 3/21/2006 Brazil
Primary
Concomitant
Liver Transplant Rejection Other Serious 2/8/2006 61 Male 197 lb 3/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 3/13/2006 57 Male 3/24/2006 Brazil
Primary
Concomitant
Pyrexia Hospitalization 9/1/2005 25 Female 3/31/2006 Consumer United Kingdom
Primary
Secondary
Renal Failure Other Serious Male 4/24/2006 Poland
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious Male 4/24/2006 Poland
Primary
Concomitant
Renal Failure Other Serious Male 4/24/2006 Poland
Primary
Concomitant
Renal Impairment Hospitalization 3/13/2006 57 Male 4/24/2006 Brazil
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/10/2006 39 Male 4/24/2006 Brazil
Primary
Concomitant
Nephrotic Syndrome Other Serious Male 4/24/2006 Poland
Primary
Concomitant
Renal Impairment Other Serious Male 4/24/2006 Poland
Primary
Concomitant
Pyrexia Hospitalization 9/1/2005 25 Female 5/4/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 2/2/2006 65 Male 5/2/2006 France
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 3/13/2006 57 Male 5/22/2006 Other Health Professional Brazil
Primary
Concomitant
Urinary Retention Hospitalization 9/26/2005 60 Male 5/24/2006 Brazil
Primary
Secondary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Hospitalization 3/1/2006 28 Male 5/24/2006 Singapore
Primary
Secondary
Kidney Transplant Rejection Other Serious 10/9/2004 44 Male 5/31/2006 Brazil
Primary
Concomitant
Liver Transplant Rejection Other Serious 2/8/2006 61 Male 197 lb 6/2/2006 United States
Primary
Secondary
Concomitant
Kidney Transplant Rejection Other Serious 6/16/2004 24 Male 6/2/2006 Other Health Professional Brazil
Primary
Concomitant
Kidney Transplant Rejection Other Serious 12/8/2004 25 Male 6/5/2006 Brazil
Primary
Concomitant
Kidney Transplant Rejection Other Serious 10/5/2005 51 Male 6/5/2006 Brazil
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 65 Male 6/2/2006 United States
Primary
Concomitant
Kidney Transplant Rejection Other Serious 12/14/2004 25 Male 6/2/2006 Other Health Professional Brazil
Primary
Concomitant
Kidney Transplant Rejection Other Serious 12/4/2004 40 Female 6/2/2006 Other Health Professional Brazil
Primary
Concomitant
Kidney Transplant Rejection Other Serious 10/13/2005 43 Male 6/2/2006 Other Health Professional Brazil
Primary
Concomitant
Erosive Oesophagitis Other Serious 4/13/2005 55 Female 6/1/2006 Other Health Professional Brazil
Primary
Secondary
Concomitant
Kidney Transplant Rejection Hospitalization 5/3/2006 19 Male 6/7/2006 Iran (Islamic Republic Of)
Primary
Concomitant
Nephropathy Toxic Other Serious 5/24/2006 59 Female 6/7/2006 Italy
Primary
Concomitant
Kidney Transplant Rejection Hospitalization 5/3/2006 19 Male 6/20/2006 Iran (Islamic Republic Of)
Primary
Concomitant
Kidney Transplant Rejection Other Serious 11/30/2005 44 Male 6/20/2006 Italy
Primary
Secondary
Concomitant
Death Death 4/6/2005 44 Male 6/28/2006 Brazil
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 4/29/2004 37 Male 6/29/2006 Brazil
Primary
Secondary
Concomitant
Diabetes Mellitus Other Serious 1/26/2006 45 Male 7/6/2006 Physician France
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 6/23/2005 30 Female 7/7/2006 Brazil
Primary
Concomitant
Urinary Tract Infection Enterococcal Other Serious 9/26/2005 23 Male 7/11/2006 Brazil
Primary
Secondary
Concomitant
Sputum Purulent Hospitalization 6/2/2005 73 Male 7/12/2006 Spain
Primary
Concomitant
Therapeutic Response Decreased Other Serious 10/1/2005 45 Female 220 lb 7/21/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 6/1/2006 48 Male 7/19/2006 Iran (Islamic Republic Of)
Primary
Secondary
Concomitant
Kidney Transplant Rejection Hospitalization 6/27/2006 53 Male 7/25/2006 Iran (Islamic Republic Of)
Primary
Concomitant
Haemodialysis Other Serious 4/19/2005 59 Male 7/25/2006 Brazil
Primary
Secondary
Concomitant
Sepsis Other Serious 6/1/2006 48 Male 7/26/2006 Iran (Islamic Republic Of)
Primary
Secondary
Concomitant
Sepsis Other Serious 48 Male 7/26/2006 Iran (Islamic Republic Of)
Primary
Secondary
Concomitant
Kidney Transplant Rejection Hospitalization 7/18/2006 48 Female 8/1/2006 Other Health Professional Iran (Islamic Republic Of)
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 7/11/2005 25 Male 8/10/2006 Brazil
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 7/11/2005 25 Male 8/10/2006 Brazil
Primary
Secondary
Concomitant
Chronic Allograft Nephropathy Other Serious 8/9/2006 40 Male 8/24/2006 Brazil
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 8/12/2006 20 Male 8/31/2006 Iran (Islamic Republic Of)
Primary
Secondary
Renal Impairment Hospitalization 11/11/2005 38 Male 9/5/2006 Brazil
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 10/1/2005 45 Female 220 lb 9/15/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/1/2005 25 Female 121 lb 9/15/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Kidney Transplant Rejection Other Serious 1/9/2006 44 Male 9/26/2006 Italy
Primary
Concomitant
Thrombocytopenia Hospitalization 8/12/2006 20 Male 9/26/2006 Iran (Islamic Republic Of)
Primary
Concomitant
Kidney Transplant Rejection Other Serious 1/9/2006 44 Male 9/27/2006 Italy
Primary
Concomitant
Refusal Of Treatment By Patient Life Threatening 8/1/2005 43 Male 10/12/2006 France
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/1/2005 63 Male 10/16/2006 United States
Primary
Concomitant
Ulcer Haemorrhage Other Serious 1/3/2006 58 Male 10/18/2006 France
Primary
Secondary
Concomitant
Myocardial Ischaemia Life Threatening 8/1/2005 43 Male 10/19/2006 France
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/1/2005 63 Male 10/19/2006 Other Health Professional United States
Primary
Concomitant
Nephropathy Toxic Other Serious 8/9/2006 40 Male 10/26/2006 Brazil
Primary
Secondary
Concomitant
Proteinuria Other Serious 2/1/2006 47 Male 10/26/2006 France
Primary
Concomitant
Weight Loss Poor Other Serious 9/1/2002 40 Female 110 lb 10/31/2006 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 60 Female 11/9/2006 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Weight Decreased Other Serious 6/22/2005 39 Male 11/15/2006 France
Primary
Concomitant
Complications Of Transplanted Kidney Other Serious 6/7/2000 62 Male 11/16/2006 France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/1/2005 63 Male 208 lb 11/28/2006 Other Health Professional United States
Primary
Concomitant
Kidney Transplant Rejection Other Serious 10/10/2005 61 Female 11/30/2006 Brazil
Primary
Concomitant
Urinary Tract Infection Other Serious 10/22/2004 49 Female 11/30/2006 Brazil
Primary
Concomitant
Thrombocytopenia Other Serious 10/28/2006 18 Male 12/6/2006 Other Health Professional Iran (Islamic Republic Of)
Primary
Concomitant
Metastases To Lymph Nodes Death 1/24/2006 61 Male 12/15/2006 United Kingdom
Primary
Concomitant
Acute Respiratory Distress Syndrome Hospitalization 2/2/2006 65 Male 12/18/2006 France
Primary
Concomitant
Obliterative Bronchiolitis Other Serious 66 Male 12/21/2006 Argentina
Primary
Secondary
Therapeutic Response Decreased Other Serious 10/1/2005 45 Female 220 lb 1/3/2007 Physician United States
Primary
Secondary
Concomitant
Skin Cancer Other Serious 1/1/2006 Male 9/12/2006 United States
Primary
Concomitant
Renal Tubular Necrosis Other Serious 5/5/2006 44 Male 170 lb 9/12/2006 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Other Serious 10/1/2005 74 Male 189 lb 10/18/2006 Physician United States
Primary
Concomitant
Urinary Fistula Other Serious 3/31/2005 53 Female 1/16/2007 Brazil
Primary
Concomitant
Thrombotic Microangiopathy Death 1/1/2004 Female 2/8/2007 Physician Netherlands
Primary
Secondary
Renal Tubular Necrosis Other Serious 12/2/2006 Male 108 lb 2/9/2007 Physician Iran (Islamic Republic Of)
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 12/26/2006 33 Male 121 lb 2/12/2007 Physician Iran (Islamic Republic Of)
Primary
Concomitant
Nephritis Interstitial Other Serious 4/29/2005 Female 208 lb 3/23/2007 Physician Brazil
Primary
Concomitant
Renal Tubular Necrosis Other Serious 6/8/2005 Male 155 lb 3/27/2007 Physician Brazil
Primary
Concomitant
Nephropathy Toxic Other Serious 1/25/2005 Female 138 lb 3/27/2007 Physician Brazil
Primary
Concomitant
Renal Failure Acute Other Serious 2/25/2005 Female 134 lb 3/27/2007 Physician Brazil
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 1/19/2005 Male 157 lb 3/29/2007 Physician Brazil
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 4/29/2004 Male 5/21/2007 Physician Brazil
Primary
Secondary
Concomitant
Vulvovaginal Pruritus Hospitalization 6/14/2005 Female 122 lb 5/24/2007 Physician Brazil
Primary
Concomitant
Erosive Oesophagitis Hospitalization 4/13/2005 Female 112 lb 5/24/2007 Physician Brazil
Primary
Secondary
Concomitant
Septic Shock Other Serious 10/1/2004 Male 165 lb 6/18/2007 Physician Brazil
Primary
Concomitant
Multi-organ Failure Other Serious 10/23/2004 Male 165 lb 6/21/2007 Physician Brazil
Primary
Concomitant
Venous Thrombosis Hospitalization 10/29/2004 Male 142 lb 6/26/2007 Physician Brazil
Primary
Secondary
Concomitant
Varicose Vein Hospitalization 10/13/2005 Female 158 lb 7/2/2007 Physician Brazil
Primary
Concomitant
Renal Impairment Other Serious 3/9/2005 Male 7/2/2007 Physician Brazil
Primary
Secondary
Concomitant
Renal Impairment Other Serious 9/12/2005 Male 161 lb 7/6/2007 Physician Brazil
Primary
Concomitant
Varicose Vein Hospitalization 4/27/2005 Female 146 lb 7/9/2007 Physician Brazil
Primary
Concomitant
Varicose Vein Hospitalization 10/13/2005 Female 158 lb 7/17/2007 Physician Brazil
Primary
Concomitant
Renal Transplant Disability 4/1/2004 36 Male 165 lb 9/21/2007 Switzerland
Primary
Concomitant
Mouth Ulceration Other Serious Unknown 10/2/2007 Other Health Professional United States
Primary
Concomitant
Pneumonia Legionella Other Serious 1/1/2007 42 Male 10/31/2007 Other Health Professional Portugal
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 1/1/2004 Male 11/8/2007 Other Health Professional Portugal
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 5/1/2007 43 Male 209 lb 11/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 10/11/2007 8 Female 39 lb 11/28/2007 Physician United States
Primary
Secondary
Concomitant
Lethargy Hospitalization 1/26/2008 Male 2/19/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 12/1/2007 3/4/2008 Physician Germany
Primary
Secondary
Concomitant
Pleura Carcinoma Other Serious 12/1/2007 Male 154 lb 3/31/2008 Other Health Professional France
Primary
Secondary
Thrombotic Microangiopathy Hospitalization 4/3/2008 26 Male 5/14/2008 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Fibroadenoma Of Breast Other Serious 1/1/2006 Female 5/20/2008 Consumer China
Primary
Concomitant
Pleural Effusion Other Serious 10/11/2007 8 Female 39 lb 5/16/2008 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 4/18/2008 40 Male 5/27/2008 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 12/1/2007 5/27/2008 Physician Germany
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 10/1/2006 26 Male 5/23/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Fibroadenoma Of Breast Other Serious 1/1/2006 37 Female 5/30/2008 Consumer China
Primary
Concomitant
Tremor Other Serious 4/18/2008 40 6/16/2008 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Metastasis Other Serious 5/27/2008 Male 137 lb 7/2/2008 Physician Austria
Primary
Secondary
Concomitant
Vomiting Hospitalization 39 Male 7/25/2008 Other Health Professional Germany
Primary
Secondary
Vomiting Hospitalization 39 Male 7/28/2008 Other Health Professional Germany
Primary
Secondary
Pancytopenia Hospitalization 5/12/2008 Male 148 lb 8/19/2008 Physician Germany
Primary
Secondary
Concomitant
Wound Infection Hospitalization 5/21/2007 61 Male 154 lb 8/21/2008 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 5/13/2008 51 Female 175 lb 9/16/2008 Physician United States
Primary
Concomitant
Kidney Transplant Rejection Other Serious 6/27/2006 Male 146 lb 9/22/2008 Physician Iran (Islamic Republic Of)
Primary
Concomitant
Renal Failure Acute Life Threatening 12/1/2007 Male 9/22/2008 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/12/2006 Male 139 lb 9/25/2008 Physician Iran (Islamic Republic Of)
Primary
Concomitant
Transitional Cell Carcinoma Other Serious 1/1/2003 33 Female 10/24/2008 Physician Taiwan, Province Of China
Primary
Concomitant
Ovarian Adhesion Hospitalization 4/20/2008 46 Female 132 lb 10/30/2008 Physician Germany
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 5/1/2008 26 Female 11/6/2008 Other Health Professional Colombia
Primary
Concomitant
Vomiting Hospitalization 1/1/2008 Female 175 lb 11/7/2008 Physician United States
Primary
Concomitant
Pruritus Hospitalization 3/13/2008 Female 110 lb 12/9/2008 Physician Germany
Primary
Concomitant
Pyrexia Other Serious 9/3/2008 Male 165 lb 12/22/2008 Physician Italy
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Recurrent Other Serious 12/8/2008 Male 231 lb 12/23/2008 Physician Germany
Primary
Concomitant
Pyrexia Other Serious 9/3/2008 Male 161 lb 1/15/2009 Physician Italy
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 12/20/2008 18 Female 1/22/2009 Other Health Professional United States
Primary
Concomitant

Drug Data