Pyrazinamide



Indications and Reactions:

Role Indications Reactions
Primary
Pulmonary Tuberculosis 33.7%
Tuberculosis 21.5%
Disseminated Tuberculosis 19.0%
Immunosuppression 8.0%
Hypertension 6.1%
Meningitis Tuberculous 4.9%
Bone Tuberculosis 4.3%
Drug Therapy 0.6%
Hyperuricaemia 0.6%
Staphylococcal Infection 0.6%
Tuberculosis Ureter 0.6%
Acute Hepatic Failure 16.7%
Hypertensive Encephalopathy 8.3%
Jaundice 8.3%
Multi-organ Failure 6.3%
Renal Failure 6.3%
Septic Shock 6.3%
Hepatic Encephalopathy 4.2%
Hepatitis 4.2%
Hepatotoxicity 4.2%
Immune Reconstitution Inflammatory Syndrome 4.2%
Immune Reconstitution Syndrome 4.2%
Liver Transplant 4.2%
Pancreatitis 4.2%
Sepsis 4.2%
Weight Decreased 4.2%
Alanine Aminotransferase Increased 2.1%
Anaphylactic Reaction 2.1%
Blood Bilirubin Increased 2.1%
Blood Uric Acid Increased 2.1%
Cough 2.1%
Secondary
Tuberculosis 35.8%
Pulmonary Tuberculosis 27.9%
Hiv Infection 7.4%
Disseminated Tuberculosis 4.2%
Product Used For Unknown Indication 4.0%
Tuberculosis Of Eye 2.9%
Meningitis Tuberculous 2.9%
Lymph Node Tuberculosis 2.8%
Drug Use For Unknown Indication 1.9%
Tuberculous Pleurisy 1.7%
Prophylaxis 1.4%
Rheumatoid Arthritis 1.3%
Antiretroviral Therapy 0.9%
Peritoneal Tuberculosis 0.9%
Extrapulmonary Tuberculosis 0.8%
Intermediate Uveitis 0.8%
Hiv Test Positive 0.7%
Tuberculosis Of Central Nervous System 0.7%
Choroiditis 0.6%
Retinal Vasculitis 0.6%
Vomiting 10.9%
Drug Reaction With Eosinophilia And Systemic Symptoms 8.9%
Tuberculosis 7.3%
Hepatitis 5.9%
Hepatocellular Damage 5.9%
Drug Rash With Eosinophilia And Systemic Symptoms 5.3%
Hepatotoxicity 5.3%
Paradoxical Drug Reaction 5.3%
Tuberculoma Of Central Nervous System 5.3%
Pyrexia 4.7%
Acute Hepatic Failure 4.2%
Liver Disorder 4.2%
Immune Reconstitution Syndrome 3.6%
Jaundice 3.6%
Toxic Epidermal Necrolysis 3.6%
Weight Decreased 3.6%
Renal Failure Acute 3.4%
Rash Maculo-papular 3.1%
Renal Failure 3.1%
Deep Vein Thrombosis 2.8%
Concomitant
Tuberculosis 32.3%
Hiv Infection 22.9%
Pulmonary Tuberculosis 13.8%
Product Used For Unknown Indication 7.7%
Drug Use For Unknown Indication 6.6%
Lymph Node Tuberculosis 1.8%
Meningitis Tuberculous 1.7%
Pneumocystis Jiroveci Pneumonia 1.5%
Antiretroviral Therapy 1.3%
Disseminated Tuberculosis 1.2%
Acquired Immunodeficiency Syndrome 1.2%
Immunosuppression 1.2%
Prophylaxis 1.2%
Rheumatoid Arthritis 1.1%
Antibiotic Prophylaxis 1.1%
Hypertension 0.8%
Oral Candidiasis 0.8%
Bone Tuberculosis 0.7%
Cardiac Failure 0.7%
Ankylosing Spondylitis 0.6%
Vomiting 15.2%
Tuberculosis 8.7%
Pyrexia 7.8%
Weight Decreased 6.6%
Immune Reconstitution Syndrome 5.7%
Toxic Epidermal Necrolysis 5.1%
Arrhythmia 4.8%
Renal Failure 4.8%
Renal Failure Acute 4.5%
Hepatitis 4.2%
Death 3.9%
Psychotic Disorder 3.9%
Pulmonary Tuberculosis 3.9%
Vision Blurred 3.6%
Drug Interaction 3.3%
Hepatitis Toxic 3.0%
Sepsis 3.0%
Sudden Death 3.0%
Neutropenia 2.7%
Renal Impairment 2.7%
Interacting
Tuberculosis 27.3%
Disseminated Tuberculosis 22.7%
Pulmonary Tuberculosis 11.4%
Stem Cell Transplant 9.1%
Hypertension 4.5%
Renal Transplant 4.5%
Pleurisy 3.4%
Prophylaxis Against Gastrointestinal Ulcer 3.4%
Renal Cell Carcinoma Stage Iv 3.4%
Hiv Infection 2.3%
Hyperlipidaemia 2.3%
Immunosuppression 2.3%
Blood Uric Acid Increased 1.1%
Grand Mal Convulsion 1.1%
Prophylaxis 1.1%
Tuberculosis 18.8%
Drug Interaction 12.5%
Hepatic Failure 12.5%
Vomiting 12.5%
Weight Decreased 12.5%
Blood Alkaline Phosphatase Increased 6.3%
Hepatitis B Surface Antigen Positive 6.3%
Hepatocellular Injury 6.3%
Hyperuricaemia 6.3%
Thrombocytosis 6.3%