Ethambutol Hydrochloride combined with Pyrazinamide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Life Threatening 9/8/2005 34 Male 136 lb 3/3/2006 Physician Japan
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 32 Male 3/30/2006 Physician Switzerland
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 32 Male 4/14/2006 Physician Switzerland
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 5/13/2003 38 Female 6/8/2006 Other Health Professional France
Primary
Secondary
Concomitant
Cardiac Tamponade Hospitalization 40 Female 6/21/2006 Physician Japan
Primary
Concomitant
Liver Disorder Death 67 Female 6/28/2006 Other Health Professional Japan
Primary
Concomitant
Urinary Tract Infection 1/17/2006 41 Female 4/24/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 4/1/2005 72 Male 8/10/2006 United States
Primary
Concomitant
Hepatitis Other Serious 6/29/2006 30 Male 8/30/2006 Physician Viet Nam
Primary
Secondary
Concomitant
Osteoarthritis Disability 6/29/2005 Female 8/30/2006 United Kingdom
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Death 55 Male 8/31/2006 Japan
Primary
Secondary
Renal Failure Acute Hospitalization 4/1/2005 72 Male 9/20/2006 Other Health Professional Japan
Primary
Concomitant
Intestinal Perforation Hospitalization 63 Male 10/3/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 19 Female 10/6/2006 Turkey
Primary
Secondary
Unresponsive To Stimuli Life Threatening 19 Female 9/29/2006 Physician Turkey
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Death 9/22/2006 29 Female 10/13/2006 United States
Primary
Secondary
Concomitant
Lymph Node Tuberculosis Other Serious 12 Male 10/6/2006 India
Primary
Secondary
Concomitant
Oesophageal Candidiasis Hospitalization 12/6/2005 32 Female 11/8/2006 Other Health Professional France
Primary
Secondary
Concomitant
Drug Level Increased Other Serious 12/1/2004 40 Female 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Drug Level Increased Other Serious 40 Female 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tuberculosis Death 9/22/2006 29 Female 11/10/2006 United States
Primary
Secondary
Concomitant
Oesophageal Candidiasis Hospitalization 12/6/2005 32 Female 11/17/2006 Other Health Professional France
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 10/26/2006 31 Male 132 lb 11/22/2006 United States
Primary
Secondary
Concomitant
Sputum Culture Positive Life Threatening 10/26/2006 31 Male 132 lb 11/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vasculitis Other Serious 3/20/2006 25 Female 134 lb 12/7/2006 Physician Uganda
Primary
Concomitant
Pneumonia Other Serious 1/1/2006 31 Male 132 lb 12/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 10/26/2006 31 Male 132 lb 12/8/2006 United States
Primary
Secondary
Concomitant
Hepatitis Other Serious 6/29/2006 30 Male 12/18/2006 Physician Viet Nam
Primary
Secondary
Concomitant
Blood Bilirubin Increased Hospitalization 12/12/2006 Male 70 lb 12/14/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/9/2006 65 Male 1/3/2007 Physician France
Primary
Concomitant
Renal Failure Hospitalization 2/15/2006 52 Male 136 lb 8/16/2006 Physician United States
Primary
Concomitant
Tuberculosis Hospitalization 12/26/2005 36 Female 127 lb 1/12/2006 Physician United States
Primary
Secondary
Concomitant
Meningitis Cryptococcal Other Serious 44 Male 2/26/2007 Other Health Professional Netherlands
Primary
Secondary
Vomiting Hospitalization 11/14/2004 41 Female 128 lb 2/16/2007 United States
Primary
Concomitant
Vomiting Death 1/2/2007 57 Male 84 lb 2/28/2007 Physician South Africa
Primary
Concomitant
Vomiting Hospitalization 31 Female 3/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/17/2006 58 Male 207 lb 3/3/2007 Pharmacist United States
Primary
Secondary
Hepatitis Hospitalization 7/30/2006 Male 127 lb 2/13/2007 Pharmacist United States
Primary
Secondary
Concomitant
Splenomegaly Other Serious 51 Male 3/13/2007 France
Primary
Secondary
Concomitant
Vomiting Death 1/2/2007 57 Male 84 lb 3/22/2007 Physician South Africa
Primary
Concomitant
Vomiting Death 1/2/2007 57 Male 84 lb 3/30/2007 Physician South Africa
Primary
Concomitant
Pancreatic Enzymes Increased Hospitalization 3/9/2007 47 Female 4/4/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Tuberculoma Of Central Nervous System Other Serious 21 Male 4/4/2007 India
Primary
Secondary
Nervous System Disorder Hospitalization 2/27/2007 Male 95 lb 4/11/2007 Physician Singapore
Primary
Secondary
Concomitant
Nephritis Interstitial Other Serious 51 Male 4/12/2007 France
Primary
Secondary
Concomitant
Pyrexia Other Serious 11/1/2004 38 Male 123 lb 4/7/2007 Physician Japan
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Other Serious 27 Male 4/10/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 27 Male 4/26/2007 Consumer Japan
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Other Serious 27 Male 4/17/2007 Japan
Primary
Secondary
Concomitant
Nervous System Disorder Hospitalization 2/27/2007 Male 95 lb 5/2/2007 Physician Singapore
Primary
Secondary
Concomitant
Status Epilepticus Life Threatening 3/22/2007 Male 5/7/2007 Other Health Professional France
Primary
Secondary
Concomitant
Urinary Casts Other Serious 11/1/2004 38 Male 123 lb 5/30/2007 Physician Japan
Primary
Secondary
Concomitant
Hypokalaemia Death 1/1/2007 24 Female 6/14/2007 Physician South Africa
Primary
Concomitant
Mycobacterium Abscessus Infection Hospitalization 73 Female 6/20/2007 Other Health Professional Japan
Primary
Secondary
Pleural Effusion Other Serious 4/1/2000 32 Female 97 lb 6/25/2007 Physician Belgium
Primary
Secondary
Concomitant
Uveitis Other Serious 40 Male 6/22/2007 India
Primary
Secondary
Tuberculosis Skin Test Positive Other Serious 73 Female 6/26/2007 Japan
Primary
Secondary
Tuberculoma Of Central Nervous System Other Serious 54 Male 6/26/2007 Taiwan, Province Of China
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 69 Female 6/28/2007 Japan
Primary
Concomitant
Haematochezia Hospitalization 1/1/2006 72 Female 6/22/2007 Denmark
Primary
Concomitant
Vision Blurred Disability 50 Female 7/9/2007 Taiwan, Province Of China
Primary
Secondary
Concomitant
Ultrasound Kidney Abnormal Hospitalization 38 Male 7/9/2007 Japan
Primary
Secondary
Vascular Pseudoaneurysm Hospitalization 11/20/2006 69 Female 7/13/2007 Japan
Primary
Secondary
Pancytopenia Other Serious 1/1/2006 71 Female 8/1/2007 Japan
Primary
Secondary
Pneumonia Other Serious 8/1/2007
Primary
Secondary
Concomitant
Meningitis Cryptococcal Life Threatening 8/1/2007
Primary
Secondary
Concomitant
Salmonella Sepsis Life Threatening 8/1/2007
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 8/1/2007
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 8/1/2007
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 8/1/2007
Primary
Secondary
Concomitant
Diarrhoea Death 8/1/2007
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Other Serious 8/1/2007
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 8/1/2007
Primary
Secondary
Concomitant
Malaria Other Serious 8/1/2007
Primary
Secondary
Concomitant
Sudden Death Death 8/1/2007
Primary
Secondary
Concomitant
Pneumonia Other Serious 8/1/2007
Primary
Secondary
Concomitant
Pericarditis Other Serious 8/1/2007
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Other Serious 8/1/2007
Primary
Secondary
Concomitant
Renal Failure Death 8/1/2007
Primary
Secondary
Concomitant
Sepsis Death 8/1/2007
Primary
Secondary
Sepsis Death 8/1/2007
Primary
Secondary
Concomitant
Kaposi's Sarcoma Other Serious 8/1/2007
Primary
Secondary
Concomitant
Kaposi's Sarcoma Other Serious 8/1/2007
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 8/1/2007
Primary
Secondary
Concomitant
Uveitis Other Serious 40 Male 7/28/2007 Physician India
Primary
Secondary
Uveitis Other Serious 40 Male 8/2/2007
Primary
Secondary
Uveitis Other Serious 40 Male 8/3/2007 Physician India
Primary
Secondary
Concomitant
Atelectasis Other Serious 9/1/2005 76 Male 8/9/2007 Japan
Primary
Concomitant
Encephalitis Hospitalization 4/1/2004 43 Male 8/17/2007 United States
Primary
Secondary
Concomitant
Urinary Retention Other Serious 9/1/2005 76 Male 8/21/2007 Japan
Primary
Secondary
Concomitant
Speech Disorder Other Serious 4/1/2004 43 Male 9/4/2007 Other Health Professional United States
Primary
Concomitant
Urinary Retention Other Serious 1/1/2005 78 Male 9/4/2007 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/30/2005 73 Female 9/12/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Paradoxical Drug Reaction Hospitalization 6/30/2007 73 Female 9/12/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Septic Shock Other Serious 42 Male 10/16/2007 Other Health Professional United States
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 73 Female 10/18/2007 Japan
Primary
Secondary
Pathogen Resistance Other Serious 73 Female 10/18/2007 Japan
Primary
Secondary
Pancreatitis Hospitalization 26 Female 11/12/2007 Physician United States
Primary
Concomitant
Pancytopenia Hospitalization 10/22/2007 35 Male 11/15/2007 Physician Zimbabwe
Primary
Secondary
Concomitant
Stridor Hospitalization 44 Female 11/19/2007 Physician France
Primary
Secondary
Concomitant
Kaposi's Sarcoma Hospitalization 33 Female 11/19/2007 Physician France
Primary
Secondary
Concomitant
Vascular Pseudoaneurysm Hospitalization 11/20/2006 69 Female 11/22/2007 Japan
Primary
Secondary
Tremor Other Serious 57 Male 11/21/2007 Physician India
Primary
Concomitant
Hyperbilirubinaemia Hospitalization 11/16/2007 34 Female 117 lb 12/20/2007 United States
Primary
Secondary
Concomitant
Pregnancy Other Serious Male 12/27/2007 Other Health Professional South Africa
Primary
Secondary
Dandy-walker Syndrome Congenital Anomaly Male 12/27/2007
Primary
Secondary
Pregnancy Other Serious Male 1/4/2008 Other Health Professional South Africa
Primary
Secondary
Drug Exposure During Pregnancy Congenital Anomaly 1/7/2008 Physician South Africa
Primary
Secondary
Vomiting Other Serious 27 Male 12/28/2007 Brazil
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Congenital Anomaly Male 12/29/2007 Physician South Africa
Primary
Secondary
Drug Exposure During Pregnancy Congenital Anomaly Male 1/10/2008 South Africa
Primary
Secondary
Drug Exposure During Pregnancy Other Serious Female 1/17/2008 South Africa
Primary
Secondary
Hyperbilirubinaemia Hospitalization 11/16/2007 34 Female 117 lb 1/25/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/5/2007 Male 1/28/2008 Physician Austria
Primary
Secondary
Concomitant
Vomiting Death 12/6/2007 48 Female 1/11/2008 Other Health Professional United States
Primary
Secondary
Drug Exposure During Pregnancy Other Serious Male 1/31/2008 South Africa
Primary
Secondary
Tuberculous Pleurisy Hospitalization 12/2/2007 83 Male 95 lb 2/1/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 11/20/2007 Female 2/8/2008 Consumer South Africa
Primary
Concomitant
Nephropathy Toxic Other Serious 7/23/2007 Male 95 lb 2/6/2008 Physician South Africa
Primary
Concomitant
Renal Failure Acute Hospitalization 1/23/2008 Female 84 lb 2/5/2008 Consumer South Africa
Primary
Concomitant
Renal Failure Hospitalization 6/30/2007 Female 2/28/2008 United Kingdom
Primary
Concomitant
Liver Disorder Hospitalization 11/27/2007 Female 128 lb 3/6/2008 Physician Japan
Primary
Secondary
Concomitant
Mycobacterium Abscessus Infection Hospitalization 73 Female 3/18/2008 Japan
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 10/22/2007 35 Male 4/7/2008 Physician Zimbabwe
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 1/1/2007 1 4/2/2008 South Africa
Primary
Secondary
Renal Failure Hospitalization 6/30/2007 Female 4/10/2008 United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 11/27/2006 28 Male 4/10/2008 Physician Viet Nam
Primary
Secondary
Concomitant
Pancytopenia Other Serious 9/18/2006 52 Female 4/10/2008 Physician Viet Nam
Primary
Secondary
Concomitant
Vomiting Other Serious 7/30/2007 4/10/2008 Physician Viet Nam
Primary
Secondary
Concomitant
Hydrocephalus Congenital Anomaly Male 4/10/2008
Primary
Secondary
Hepatitis Other Serious 3/22/2006 25 Male 4/11/2008 Physician Viet Nam
Primary
Secondary
Concomitant
Hyperbilirubinaemia Other Serious 4/7/2006 25 Male 4/11/2008 Physician Viet Nam
Primary
Secondary
Concomitant
Pyrexia Other Serious 10/27/2006 28 Female 4/11/2008 Physician Viet Nam
Primary
Secondary
Concomitant
Hyperbilirubinaemia Other Serious 12/5/2006 29 Male 4/11/2008 Physician Viet Nam
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/26/2006 24 Female 4/11/2008 Physician Viet Nam
Primary
Secondary
Concomitant
Vomiting Other Serious 7/9/2007 4/11/2008 Physician Viet Nam
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 11/3/2005 45 Male 4/14/2008 Physician Viet Nam
Primary
Concomitant
Hepatitis Other Serious 6/29/2006 30 Male 4/14/2008 Physician Viet Nam
Primary
Secondary
Concomitant
Hepatitis Other Serious 1/15/2007 25 Male 4/14/2008 Physician Viet Nam
Primary
Secondary
Concomitant
Sepsis Death 1/30/2008 75 Male 4/17/2008 Physician Greece
Primary
Concomitant
Tachypnoea Other Serious 11/26/1986 Male 103 lb 4/22/2008 Physician United States
Primary
Concomitant
Pyrexia Other Serious 2/25/2008 68 Female 4/25/2008 Consumer Thailand
Primary
Concomitant
Neutropenia Life Threatening 11/8/2007 38 Male 4/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 53 Female 4/26/2008 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 11/1/2007 Female 5/1/2008 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Pyrexia Other Serious 2/25/2008 68 Female 5/6/2008 Consumer Thailand
Primary
Concomitant
Tuberculoid Leprosy Other Serious 37 Male 5/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tuberculoid Leprosy Other Serious 37 Male 5/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 28 Female 5/14/2008 Physician United Kingdom
Primary
Secondary
Pyrexia Other Serious 2/25/2008 68 Female 5/19/2008 Consumer Thailand
Primary
Concomitant

Drug Data