Primary |
Hormone Replacement Therapy |
54.7% |
Menopausal Symptoms |
8.0% |
Oestrogen Replacement Therapy |
7.6% |
Vulvovaginal Dryness |
5.3% |
Hypertension |
3.6% |
Menopause |
2.8% |
Hot Flush |
2.5% |
Dyspareunia |
2.0% |
Product Used For Unknown Indication |
1.6% |
Vulvovaginal Discomfort |
1.5% |
Drug Use For Unknown Indication |
1.4% |
Atrophic Vulvovaginitis |
1.3% |
Blood Cholesterol Increased |
1.3% |
Off Label Use |
1.2% |
Depression |
0.9% |
Hysterectomy |
0.9% |
Vulvovaginal Burning Sensation |
0.9% |
Thyroid Disorder |
0.8% |
Cardiac Disorder |
0.8% |
Hypothyroidism |
0.7% |
|
Breast Cancer |
56.9% |
Breast Cancer Metastatic |
13.9% |
Drug Ineffective |
5.4% |
Breast Cancer Female |
4.6% |
Ovarian Cancer |
2.2% |
Contralateral Breast Cancer |
1.8% |
Thrombosis |
1.8% |
Breast Cancer Recurrent |
1.7% |
Ovarian Cancer Metastatic |
1.7% |
Cerebrovascular Accident |
1.6% |
Hot Flush |
1.4% |
Breast Cancer In Situ |
1.1% |
Vulvovaginal Burning Sensation |
0.9% |
Myocardial Infarction |
0.8% |
Weight Increased |
0.7% |
Pulmonary Embolism |
0.7% |
Vaginal Haemorrhage |
0.7% |
Product Quality Issue |
0.7% |
Malaise |
0.7% |
Vulvovaginal Pruritus |
0.7% |
|
Secondary |
Hormone Replacement Therapy |
74.1% |
Menopausal Symptoms |
6.8% |
Menopause |
5.6% |
Hypertension |
2.1% |
Hot Flush |
1.6% |
Oestrogen Replacement Therapy |
1.4% |
Vulvovaginal Dryness |
1.2% |
Depression |
1.0% |
Osteoporosis |
0.6% |
Dyspareunia |
0.6% |
Blood Cholesterol Increased |
0.6% |
Hormone Therapy |
0.6% |
Thyroid Disorder |
0.5% |
Hypothyroidism |
0.5% |
Anxiety |
0.5% |
Product Used For Unknown Indication |
0.5% |
Blood Pressure |
0.5% |
Night Sweats |
0.5% |
Pain |
0.4% |
Vulvovaginal Discomfort |
0.4% |
|
Breast Cancer |
41.3% |
Breast Cancer Female |
36.3% |
Breast Cancer Metastatic |
8.7% |
Drug Ineffective |
2.1% |
Ovarian Cancer |
1.7% |
Progesterone Receptor Assay Positive |
1.7% |
Breast Cancer In Situ |
1.4% |
Thrombosis |
0.9% |
Cerebrovascular Accident |
0.8% |
Pulmonary Embolism |
0.8% |
Contralateral Breast Cancer |
0.7% |
Deep Vein Thrombosis |
0.6% |
Breast Cancer Recurrent |
0.5% |
Ovarian Cancer Metastatic |
0.5% |
Myocardial Infarction |
0.4% |
Weight Decreased |
0.4% |
Weight Increased |
0.4% |
Uterine Leiomyoma |
0.3% |
Vaginal Haemorrhage |
0.3% |
Hot Flush |
0.3% |
|
Concomitant |
Product Used For Unknown Indication |
22.3% |
Drug Use For Unknown Indication |
14.2% |
Osteoporosis |
7.1% |
Hypertension |
6.6% |
Pain |
6.3% |
Depression |
5.1% |
Hormone Replacement Therapy |
5.0% |
Rheumatoid Arthritis |
4.8% |
Gastrooesophageal Reflux Disease |
3.8% |
Arthritis |
2.9% |
Asthma |
2.8% |
Anxiety |
2.7% |
Blood Cholesterol Increased |
2.5% |
Osteopenia |
2.4% |
Smoking Cessation Therapy |
2.3% |
Hypothyroidism |
2.2% |
Fibromyalgia |
2.0% |
Multiple Sclerosis |
1.9% |
Diabetes Mellitus |
1.7% |
Chronic Obstructive Pulmonary Disease |
1.6% |
|
Vomiting |
13.5% |
Weight Decreased |
11.7% |
Weight Increased |
10.2% |
Nausea |
6.9% |
Urinary Tract Infection |
5.7% |
Drug Ineffective |
5.1% |
Pain |
4.9% |
Vision Blurred |
4.5% |
Type 2 Diabetes Mellitus |
4.0% |
Tremor |
3.7% |
Myocardial Infarction |
3.5% |
Headache |
3.2% |
Rash |
3.1% |
Dyspnoea |
3.0% |
Pruritus |
3.0% |
Urticaria |
2.9% |
Somnolence |
2.9% |
Wrong Technique In Drug Usage Process |
2.9% |
Pain In Extremity |
2.7% |
Transient Ischaemic Attack |
2.4% |
|
Interacting |
Mental Disorder |
20.8% |
Somatoform Disorder |
10.4% |
Depression |
8.4% |
Epilepsy |
7.8% |
Menopause |
7.8% |
Blood Cholesterol Increased |
5.8% |
Herpes Zoster |
5.2% |
Hypertension |
5.2% |
Drug Use For Unknown Indication |
3.9% |
Systemic Lupus Erythematosus |
3.9% |
Hormone Replacement Therapy |
3.2% |
Pain |
3.2% |
Asthma |
2.6% |
Oral Surgery |
2.6% |
Headache |
1.9% |
Vaginal Disorder |
1.9% |
Back Pain |
1.3% |
Bladder Disorder |
1.3% |
Crohn's Disease |
1.3% |
Gastrooesophageal Reflux Disease |
1.3% |
|
Suicidal Ideation |
14.3% |
Vomiting |
11.4% |
Drug Interaction |
8.6% |
Akathisia |
5.7% |
Nausea |
5.7% |
Tremor |
5.7% |
Vaginal Haemorrhage |
5.7% |
Vulvovaginal Pain |
5.7% |
Weight Decreased |
5.7% |
Acid Base Balance Abnormal |
2.9% |
Balance Disorder |
2.9% |
Drug Ineffective |
2.9% |
Epilepsy |
2.9% |
Hot Flush |
2.9% |
Malaise |
2.9% |
Night Sweats |
2.9% |
Physical Assault |
2.9% |
Precerebral Artery Occlusion |
2.9% |
Somnolence |
2.9% |
Unevaluable Event |
2.9% |
|