| Primary |
| Hormone Replacement Therapy |
54.7% |
| Menopausal Symptoms |
8.0% |
| Oestrogen Replacement Therapy |
7.6% |
| Vulvovaginal Dryness |
5.3% |
| Hypertension |
3.6% |
| Menopause |
2.8% |
| Hot Flush |
2.5% |
| Dyspareunia |
2.0% |
| Product Used For Unknown Indication |
1.6% |
| Vulvovaginal Discomfort |
1.5% |
| Drug Use For Unknown Indication |
1.4% |
| Atrophic Vulvovaginitis |
1.3% |
| Blood Cholesterol Increased |
1.3% |
| Off Label Use |
1.2% |
| Depression |
0.9% |
| Hysterectomy |
0.9% |
| Vulvovaginal Burning Sensation |
0.9% |
| Thyroid Disorder |
0.8% |
| Cardiac Disorder |
0.8% |
| Hypothyroidism |
0.7% |
|
| Breast Cancer |
56.9% |
| Breast Cancer Metastatic |
13.9% |
| Drug Ineffective |
5.4% |
| Breast Cancer Female |
4.6% |
| Ovarian Cancer |
2.2% |
| Contralateral Breast Cancer |
1.8% |
| Thrombosis |
1.8% |
| Breast Cancer Recurrent |
1.7% |
| Ovarian Cancer Metastatic |
1.7% |
| Cerebrovascular Accident |
1.6% |
| Hot Flush |
1.4% |
| Breast Cancer In Situ |
1.1% |
| Vulvovaginal Burning Sensation |
0.9% |
| Myocardial Infarction |
0.8% |
| Weight Increased |
0.7% |
| Pulmonary Embolism |
0.7% |
| Vaginal Haemorrhage |
0.7% |
| Product Quality Issue |
0.7% |
| Malaise |
0.7% |
| Vulvovaginal Pruritus |
0.7% |
|
| Secondary |
| Hormone Replacement Therapy |
74.1% |
| Menopausal Symptoms |
6.8% |
| Menopause |
5.6% |
| Hypertension |
2.1% |
| Hot Flush |
1.6% |
| Oestrogen Replacement Therapy |
1.4% |
| Vulvovaginal Dryness |
1.2% |
| Depression |
1.0% |
| Osteoporosis |
0.6% |
| Dyspareunia |
0.6% |
| Blood Cholesterol Increased |
0.6% |
| Hormone Therapy |
0.6% |
| Thyroid Disorder |
0.5% |
| Hypothyroidism |
0.5% |
| Anxiety |
0.5% |
| Product Used For Unknown Indication |
0.5% |
| Blood Pressure |
0.5% |
| Night Sweats |
0.5% |
| Pain |
0.4% |
| Vulvovaginal Discomfort |
0.4% |
|
| Breast Cancer |
41.3% |
| Breast Cancer Female |
36.3% |
| Breast Cancer Metastatic |
8.7% |
| Drug Ineffective |
2.1% |
| Ovarian Cancer |
1.7% |
| Progesterone Receptor Assay Positive |
1.7% |
| Breast Cancer In Situ |
1.4% |
| Thrombosis |
0.9% |
| Cerebrovascular Accident |
0.8% |
| Pulmonary Embolism |
0.8% |
| Contralateral Breast Cancer |
0.7% |
| Deep Vein Thrombosis |
0.6% |
| Breast Cancer Recurrent |
0.5% |
| Ovarian Cancer Metastatic |
0.5% |
| Myocardial Infarction |
0.4% |
| Weight Decreased |
0.4% |
| Weight Increased |
0.4% |
| Uterine Leiomyoma |
0.3% |
| Vaginal Haemorrhage |
0.3% |
| Hot Flush |
0.3% |
|
| Concomitant |
| Product Used For Unknown Indication |
22.3% |
| Drug Use For Unknown Indication |
14.2% |
| Osteoporosis |
7.1% |
| Hypertension |
6.6% |
| Pain |
6.3% |
| Depression |
5.1% |
| Hormone Replacement Therapy |
5.0% |
| Rheumatoid Arthritis |
4.8% |
| Gastrooesophageal Reflux Disease |
3.8% |
| Arthritis |
2.9% |
| Asthma |
2.8% |
| Anxiety |
2.7% |
| Blood Cholesterol Increased |
2.5% |
| Osteopenia |
2.4% |
| Smoking Cessation Therapy |
2.3% |
| Hypothyroidism |
2.2% |
| Fibromyalgia |
2.0% |
| Multiple Sclerosis |
1.9% |
| Diabetes Mellitus |
1.7% |
| Chronic Obstructive Pulmonary Disease |
1.6% |
|
| Vomiting |
13.5% |
| Weight Decreased |
11.7% |
| Weight Increased |
10.2% |
| Nausea |
6.9% |
| Urinary Tract Infection |
5.7% |
| Drug Ineffective |
5.1% |
| Pain |
4.9% |
| Vision Blurred |
4.5% |
| Type 2 Diabetes Mellitus |
4.0% |
| Tremor |
3.7% |
| Myocardial Infarction |
3.5% |
| Headache |
3.2% |
| Rash |
3.1% |
| Dyspnoea |
3.0% |
| Pruritus |
3.0% |
| Urticaria |
2.9% |
| Somnolence |
2.9% |
| Wrong Technique In Drug Usage Process |
2.9% |
| Pain In Extremity |
2.7% |
| Transient Ischaemic Attack |
2.4% |
|
| Interacting |
| Mental Disorder |
20.8% |
| Somatoform Disorder |
10.4% |
| Depression |
8.4% |
| Epilepsy |
7.8% |
| Menopause |
7.8% |
| Blood Cholesterol Increased |
5.8% |
| Herpes Zoster |
5.2% |
| Hypertension |
5.2% |
| Drug Use For Unknown Indication |
3.9% |
| Systemic Lupus Erythematosus |
3.9% |
| Hormone Replacement Therapy |
3.2% |
| Pain |
3.2% |
| Asthma |
2.6% |
| Oral Surgery |
2.6% |
| Headache |
1.9% |
| Vaginal Disorder |
1.9% |
| Back Pain |
1.3% |
| Bladder Disorder |
1.3% |
| Crohn's Disease |
1.3% |
| Gastrooesophageal Reflux Disease |
1.3% |
|
| Suicidal Ideation |
14.3% |
| Vomiting |
11.4% |
| Drug Interaction |
8.6% |
| Akathisia |
5.7% |
| Nausea |
5.7% |
| Tremor |
5.7% |
| Vaginal Haemorrhage |
5.7% |
| Vulvovaginal Pain |
5.7% |
| Weight Decreased |
5.7% |
| Acid Base Balance Abnormal |
2.9% |
| Balance Disorder |
2.9% |
| Drug Ineffective |
2.9% |
| Epilepsy |
2.9% |
| Hot Flush |
2.9% |
| Malaise |
2.9% |
| Night Sweats |
2.9% |
| Physical Assault |
2.9% |
| Precerebral Artery Occlusion |
2.9% |
| Somnolence |
2.9% |
| Unevaluable Event |
2.9% |
|