Metformin combined with Premarin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Overdose Hospitalization 1/1/2004 53 Female 220 lb 1/19/2006 Lawyer United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 1/1/2002 52 Female 190 lb 1/23/2006 Lawyer United States
Primary
Concomitant
Skin Cancer Hospitalization 8/22/2002 50 Female 198 lb 2/10/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2003 59 Female 271 lb 2/16/2006 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2001 54 Female 185 lb 2/22/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 8/20/2001 64 Female 121 lb 2/24/2006 Lawyer United States
Primary
Concomitant
Viral Infection Hospitalization 1/1/2001 68 Female 240 lb 3/1/2006 Physician United States
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 4/16/2004 81 Female 141 lb 3/10/2006 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2004 53 Female 220 lb 3/24/2006 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/1/2000 64 Female 209 lb 3/27/2006 Lawyer United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 11/2/2002 81 Female 141 lb 3/27/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 6/1/2000 66 Female 157 lb 3/31/2006 Physician United States
Primary
Concomitant
Shoulder Pain Hospitalization 1/1/2002 64 Female 234 lb 4/4/2006 Lawyer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 3/1/2005 83 Female 3/30/2006 Pharmacist Canada
Primary
Concomitant
Shoulder Pain Hospitalization 1/1/2002 64 Female 234 lb 4/10/2006 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 3/1/2006 83 Female 4/4/2006 Pharmacist Canada
Primary
Concomitant
Victim Of Crime Other Serious 1/1/2004 53 Female 220 lb 4/24/2006 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 6/1/2003 62 Female 163 lb 4/25/2006 Lawyer United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2000 64 Female 121 lb 4/28/2006 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 6/1/2003 62 Female 163 lb 5/3/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 4/17/2006 55 Female 190 lb 5/3/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 4/17/2006 55 Female 190 lb 5/12/2006 Physician United States
Primary
Concomitant
Thinking Abnormal 4/1/2005 Female 3/23/2006 Consumer United States
Primary
Concomitant
Hepatic Steatosis Other Serious 3/23/2006 46 Female 5/24/2006 Physician United States
Primary
Concomitant
Weight Increased Other Serious 2/1/2004 44 Female 244 lb 4/18/2006 Lawyer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 11/1/2005 60 Female 191 lb 4/20/2006 Consumer United States
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 10/1/2003 Female 294 lb 6/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urticaria Other Serious 4/21/2005 50 Female 299 lb 5/18/2006 Physician United States
Primary
Concomitant
Drug Ineffective 57 Female 7/21/2006 Consumer United States
Primary
Concomitant
Oedema Peripheral 1/1/2003 65 Female 7/21/2006 Consumer United States
Primary
Concomitant
Suicidal Ideation Death 11/1/2004 57 Female 10/6/2006 Consumer United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 10/14/2006 56 Female 11/13/2006 Other Health Professional United States
Primary
Concomitant
Insomnia 6/1/2006 58 Female 11/29/2006 Consumer United States
Primary
Secondary
Concomitant
Injection Site Pain 5/1/2006 Female 12/20/2006 Pharmacist United States
Primary
Concomitant
Pain Other Serious 1/1/2007 Female 192 lb 9/24/2007 Consumer United States
Primary
Concomitant
Uterine Leiomyoma Other Serious 9/1/2007 Female 168 lb 10/26/2007 Consumer United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 1/1/1980 35 Female 154 lb 3/25/2008 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2003 59 Female 4/23/2008 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 1/1/1980 35 Female 154 lb 4/28/2008 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/13/2003 59 Female 5/8/2008 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 1/1/1999 35 Female 154 lb 5/19/2008 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 1/1/1999 53 Female 154 lb 6/5/2008 Physician United States
Primary
Concomitant
Urinary Incontinence Other Serious 12/31/2007 55 Female 6/30/2008 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/13/2003 59 Female 7/3/2008 Physician United States
Primary
Concomitant
Weight Increased 1/1/2004 70 Female 7/24/2008 Consumer United States
Primary
Concomitant
Weight Increased 8/1/2005 72 Female 7/24/2008 Consumer United States
Primary
Concomitant
Joint Swelling 5/1/2007 70 Female 7/24/2008 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 3/12/2008 66 Female 146 lb 9/9/2008 Consumer United States
Primary
Concomitant
Musculoskeletal Pain Other Serious 6/24/2008 Female 10/15/2008 Consumer United States
Primary
Concomitant
Heart Injury Hospitalization 3/1/2006 55 Female 198 lb 1/13/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 12/1/2005 73 Female 159 lb 2/4/2009 Consumer United States
Primary
Concomitant
Blood Glucose Increased 11/27/2008 Female 2/24/2009 United States
Primary
Concomitant
Product Quality Issue 7/1/2008 62 Female 2/27/2009 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 6/1/2001 58 Female 175 lb 3/6/2009 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious 11/29/2007 Female 213 lb 3/6/2009 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 3/27/2008 65 Female 153 lb 2/26/2009 United States
Primary
Concomitant
Ventricular Fibrillation Death 3/11/2009 Female 229 lb 3/13/2009 Pharmacist United States
Primary
Concomitant
Rash Other Serious 1/1/2008 58 Female 130 lb 3/20/2009 Physician India
Primary
Concomitant
Breast Cancer Female Other Serious 5/1/2002 Female 280 lb 4/8/2009 Lawyer United States
Primary
Secondary
Concomitant
Breast Cancer Female Other Serious 1/25/1998 Female 141 lb 4/17/2009 Lawyer United States
Primary
Secondary
Concomitant
Breast Cancer Female Other Serious 2/1/2004 Female 5/11/2009 Lawyer United States
Primary
Secondary
Concomitant
Breast Cancer Female Other Serious 7/1/2004 Female 146 lb 6/8/2009 Lawyer United States
Primary
Secondary
Concomitant
Breast Cancer Other Serious 5/19/1999 Female 154 lb 6/16/2009 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 72 Female 7/2/2009 United States
Primary
Concomitant
Off Label Use Hospitalization 6/1/2008 Female 250 lb 8/4/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 3/18/2008 56 Female 258 lb 7/22/2009 United States
Primary
Concomitant
Breast Cancer Other Serious 3/1/2003 Female 240 lb 8/7/2009 Lawyer United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/18/2008 56 Female 258 lb 8/6/2009 Lawyer United States
Primary
Concomitant
Breast Cancer Other Serious 5/19/1999 Female 154 lb 8/26/2009 Lawyer United States
Primary
Secondary
Concomitant
Potentiating Drug Interaction Disability 3/23/2009 43 Female 9/15/2009 Pharmacist United States
Primary
Secondary
Concomitant
Viral Upper Respiratory Tract Infection Other Serious 46 Female 223 lb 10/22/2009 Lawyer United States
Primary
Concomitant
Viral Upper Respiratory Tract Infection Other Serious 46 Female 223 lb 10/27/2009 Lawyer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2006 Female 150 lb 11/4/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 61 Female 117 lb 12/30/2009 Other Health Professional Canada
Primary
Concomitant
Umbilical Hernia Repair Other Serious 2/24/2003 Female 1/25/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/17/2009 Female 159 lb 1/29/2010 Other Health Professional Canada
Primary
Concomitant
Syncope Other Serious 1/1/2007 Female 270 lb 3/19/2010 Physician United States
Primary
Concomitant
Urinary Incontinence Other Serious 12/31/2007 55 Female 3/30/2010 Physician United States
Primary
Concomitant
Optic Neuropathy Other Serious 8/27/2009 65 Female 4/5/2010 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious Female 280 lb 4/8/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/1997 57 Female 120 lb 4/29/2010 Consumer United States
Primary
Secondary
Concomitant
Muscle Injury Other Serious 2/17/2010 54 Female 4/30/2010 Consumer United States
Primary
Concomitant
Breast Cancer Female Other Serious 12/27/2005 61 Female 6/23/2010 Lawyer United States
Primary
Secondary
Concomitant
Breast Cancer Female Other Serious 10/8/1998 58 Female 280 lb 6/24/2010 Lawyer United States
Primary
Secondary
Concomitant
Breast Cancer Female Other Serious 2/1/2002 47 Female 6/24/2010 Lawyer United States
Primary
Secondary
Concomitant
Breast Cancer Female Other Serious 1/1/2002 54 Female 300 lb 6/24/2010 Lawyer United States
Primary
Secondary
Concomitant
Pruritus 5/5/2007 59 Female 251 lb 7/13/2010 Consumer United States
Primary
Concomitant
Stomatitis 1/1/2007 66 Female 7/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased 1/1/2007 58 Female 160 lb 7/19/2010 Consumer United States
Primary
Concomitant
Middle Insomnia 3/15/2008 63 Female 168 lb 7/21/2010 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 1/1/2009 38 Female 225 lb 8/23/2010 Consumer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 55 Female 185 lb 8/25/2010 United States
Primary
Concomitant
Viral Infection Hospitalization 5/26/2010 61 Female 285 lb 8/26/2010 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 52 Female 8/18/2010 United States
Primary
Concomitant
Blood Glucose Increased Female 190 lb 8/29/2010 Consumer United States
Primary
Concomitant
Flushing Female 195 lb 8/29/2010 Consumer United States
Primary
Concomitant
Cardiac Failure Death Female 8/20/2010 Pharmacist United States
Primary
Concomitant
Pancreatitis Other Serious 1/1/2005 67 Female 175 lb 9/17/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 1/1/2004 64 Female 184 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 8/1/2003 43 Female 135 lb 9/20/2010 United States
Primary
Concomitant
Vulvovaginal Erythema 1/1/2008 71 Female 208 lb 9/23/2010 Physician United States
Primary
Concomitant
Product Quality Issue 5/15/2009 64 Female 9/23/2010 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 4/7/2004 68 Female 133 lb 9/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Multiple Fractures Hospitalization 64 Female 10/4/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 4/7/2004 68 Female 133 lb 10/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Irritation Other Serious Female 186 lb 10/21/2010 Consumer Canada
Primary
Concomitant
Syncope Other Serious 1/1/2007 42 Female 270 lb 10/22/2010 Physician United States
Primary
Concomitant
Asthenia 11/19/2010 66 Female 212 lb 12/1/2010 Consumer United States
Primary
Concomitant
Nephropathy Other Serious 10/19/2010 75 Female 146 lb 12/13/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Injection Site Swelling 8/3/2010 44 Female 1/29/2011 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 1/14/2011 70 Female 2/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 1/1/2010 50 Female 12/16/2010 United States
Primary
Concomitant
Migraine Hospitalization 1/1/2005 41 Female 2/16/2011 Physician United States
Primary
Concomitant
Ear Infection Other Serious 12/1/2010 2/23/2011 Other Health Professional Canada
Primary
Concomitant
Breast Cancer Female Hospitalization 10/23/1998 62 Female 181 lb 3/2/2011 Lawyer United States
Primary
Secondary
Concomitant
Breast Cancer Female Hospitalization 10/23/1998 62 Female 179 lb 3/3/2011 Lawyer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 1/14/2011 70 Female 3/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Breast Cancer Female Other Serious 10/23/1998 62 Female 181 lb 3/7/2011 Lawyer United States
Primary
Secondary
Concomitant
Drug Ineffective 2/1/2011 87 Female 196 lb 3/9/2011 Consumer United States
Primary
Concomitant
Depression Other Serious 3/20/2009 53 Female 3/10/2011 Lawyer United States
Primary
Concomitant
Dysphagia Other Serious 1/1/2003 46 Male 3/11/2011 Lawyer United States
Primary
Concomitant
Breast Cancer Female Hospitalization 10/23/1998 62 Female 179 lb 3/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Drug Ineffective 2/1/2011 87 Female 196 lb 4/14/2011 Consumer United States
Primary
Concomitant
Vulvovaginal Mycotic Infection Female 4/20/2011 Other Health Professional United States
Primary
Concomitant
Injection Site Haematoma Hospitalization 3/1/2010 4/26/2011 Consumer United States
Primary
Concomitant
Breast Cancer Female Other Serious 9/18/2002 59 Female 5/3/2011 Lawyer United States
Primary
Secondary
Concomitant
Breast Cancer Female Other Serious 1/1/2001 60 Female 201 lb 5/3/2011 Lawyer United States
Primary
Secondary
Concomitant
Angina Pectoris Other Serious 3/28/2006 Female 5/5/2011 United States
Primary
Concomitant
Breast Cancer Female Other Serious 1/18/2002 60 Female 269 lb 6/9/2011 Lawyer United States
Primary
Secondary
Concomitant
Drug Ineffective 1/1/2010 64 Female 201 lb 6/28/2011 Consumer United States
Primary
Concomitant
Vulvovaginal Erythema 5/1/2011 78 Female 161 lb 6/29/2011 Consumer United States
Primary
Concomitant
Hyperhidrosis Other Serious 7/1/2011 52 Female 185 lb 7/11/2011 Consumer United States
Primary
Concomitant
Fluid Retention 1/1/2011 73 Female 154 lb 7/21/2011 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Female 7/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious Female 160 lb 8/17/2011 Consumer United States
Primary
Secondary
Concomitant
Joint Swelling Other Serious Female 160 lb 8/19/2011 Consumer United States
Primary
Secondary
Concomitant
Blood Cholesterol Increased 11/1/2004 51 Female 185 lb 9/22/2011 Consumer United States
Primary
Concomitant
Obesity 7/1/2004 57 Female 182 lb 9/22/2011 United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2011 73 Female 229 lb 10/19/2011 Physician United States
Primary
Concomitant
Constipation Other Serious 1/1/2011 73 Female 229 lb 10/27/2011 Physician United States
Primary
Concomitant
Condition Aggravated Other Serious 11/21/2011 54 Female 188 lb 12/30/2011 Consumer United States
Primary
Concomitant
Neck Pain 12/1/2011 62 Female 229 lb 1/20/2012 Consumer United States
Primary
Concomitant
Vaginal Discharge Female 180 lb 2/24/2012 Consumer United States
Primary
Concomitant
Vaginal Discharge Female 180 lb 3/19/2012 Consumer United States
Primary
Concomitant
Pain In Extremity Hospitalization 12/23/2008 59 Female 159 lb 3/30/2012 Physician United States
Primary
Concomitant
Convulsion Hospitalization 3/12/2012 55 Female 190 lb 4/3/2012 Consumer United States
Primary
Concomitant
Disturbance In Attention Other Serious 1/1/2012 81 Female 157 lb 4/12/2012 Consumer United States
Primary
Concomitant
Pruritus Other Serious Female 159 lb 4/26/2012 Physician United States
Primary
Concomitant
Vulvovaginal Burning Sensation 4/15/2012 81 Female 155 lb 4/26/2012 Consumer United States
Primary
Concomitant
Discomfort 4/1/2012 81 Female 155 lb 5/10/2012 Consumer United States
Primary
Concomitant

Drug Data