Letrozole



Indications and Reactions:

Role Indications Reactions
Primary
Breast Cancer 49.9%
Breast Cancer Metastatic 13.5%
Product Used For Unknown Indication 10.4%
Hypertension 6.7%
Osteoporosis 2.5%
Depression 2.0%
Prophylaxis 1.7%
Diabetes Mellitus 1.5%
Chronic Obstructive Pulmonary Disease 1.2%
Metastases To Liver 1.2%
Non-small Cell Lung Cancer 1.2%
Invasive Ductal Breast Carcinoma 1.1%
Ovulation Induction 1.1%
Hypercholesterolaemia 1.0%
Hypothyroidism 1.0%
Pyrexia 1.0%
Infertility 0.9%
Vomiting 0.9%
Bipolar Disorder 0.8%
Breast Cancer Stage Ii 0.8%
Death 17.0%
Neoplasm Malignant 11.7%
Vomiting 7.3%
Arthralgia 5.7%
Dysphagia 5.7%
Neoplasm Progression 5.7%
Ejection Fraction Decreased 4.9%
Dyspnoea 4.5%
Pain In Extremity 4.5%
Psychotic Disorder 4.5%
Sjogren's Syndrome 3.6%
Urticaria 3.6%
Product Substitution Issue 3.2%
Carpal Tunnel Syndrome 2.8%
Premature Baby 2.8%
Spinal Compression Fracture 2.8%
Adverse Drug Reaction 2.4%
Cardiac Failure 2.4%
Concomitant Disease Progression 2.4%
Fatigue 2.4%
Secondary
Breast Cancer 47.6%
Breast Cancer Metastatic 15.9%
Product Used For Unknown Indication 12.7%
Hypertension 2.3%
Drug Use For Unknown Indication 2.3%
Metastases To Liver 2.1%
Breast Cancer Stage Ii 2.0%
Prophylaxis 2.0%
Osteoporosis 1.9%
Invasive Ductal Breast Carcinoma 1.7%
Metastases To Bone 1.6%
Atrial Fibrillation 1.3%
Pain 1.2%
Diabetes Mellitus 1.0%
Ovarian Cancer 1.0%
Hypercholesterolaemia 0.7%
Her-2 Positive Breast Cancer 0.6%
Hormone Therapy 0.6%
Hypothyroidism 0.6%
Infertility 0.6%
Malignant Neoplasm Progression 9.6%
Vomiting 8.9%
Neoplasm Progression 8.3%
Progressive Multifocal Leukoencephalopathy 7.6%
Myalgia 7.0%
Disease Progression 5.7%
Osteonecrosis 5.1%
Arthralgia 4.5%
Neutrophil Pelger-huet Anomaly Present 4.5%
Pain In Extremity 4.5%
Renal Failure 4.5%
Tenderness 4.5%
Hepatic Failure 3.8%
Premature Baby 3.8%
Suicidal Ideation 3.8%
Metastatic Neoplasm 3.2%
Renal Impairment 3.2%
Acute Myeloid Leukaemia 2.5%
Anaemia 2.5%
Breast Cancer 2.5%
Concomitant
Breast Cancer 32.8%
Product Used For Unknown Indication 15.5%
Breast Cancer Metastatic 9.1%
Metastases To Bone 6.8%
Drug Use For Unknown Indication 6.7%
Pain 5.9%
Hypertension 4.0%
Diabetes Mellitus 2.5%
Prophylaxis 2.1%
Anaemia 1.6%
Infertility Female 1.5%
Anxiety 1.5%
Nausea 1.5%
Osteoporosis 1.5%
Hypercalcaemia 1.4%
Hypothyroidism 1.3%
Rheumatoid Arthritis 1.2%
Bone Disorder 1.1%
Chronic Obstructive Pulmonary Disease 1.0%
Constipation 1.0%
Weight Decreased 20.1%
Tooth Extraction 8.3%
Vomiting 7.4%
Vertigo 5.7%
Wound Infection Staphylococcal 5.7%
Weight Increased 5.2%
White Blood Cell Count Decreased 4.8%
Osteonecrosis 4.4%
Osteonecrosis Of Jaw 3.9%
Pain In Extremity 3.9%
Rash 3.9%
Ventricular Septal Defect 3.9%
Death 3.1%
Renal Failure Acute 3.1%
Thrombocytopenia 3.1%
Vertigo Positional 3.1%
Disease Progression 2.6%
Insomnia 2.6%
Pain 2.6%
Pneumonia 2.6%
Interacting
Breast Cancer 16.7%
Hypertension 11.1%
Oral Pain 8.3%
Blood Cholesterol Increased 5.6%
Diarrhoea 5.6%
Folate Deficiency 5.6%
Hypothyroidism 5.6%
Nausea 5.6%
Neuralgia 5.6%
Product Used For Unknown Indication 5.6%
Stomatitis 5.6%
Vitamin B12 Deficiency 5.6%
Breast Cancer Female 2.8%
Breast Cancer Metastatic 2.8%
Chronic Myeloid Leukaemia 2.8%
Disease Recurrence 2.8%
Renal Cancer 2.8%
Headache 18.2%
Stomatitis 18.2%
Bradycardia 9.1%
Cerebrovascular Accident 9.1%
Respiratory Depression 9.1%
Somnolence 9.1%
Spinal Compression Fracture 9.1%
Thrombocytopenia 9.1%
Weight Fluctuation 9.1%