Letrozole combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tooth Extraction Other Serious 9/1/2005 62 Female 199 lb 1/27/2006 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 9/1/2005 62 Female 199 lb 2/7/2006 Physician United States
Primary
Concomitant
Osteonecrosis Life Threatening Female 199 lb Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 10/29/2003 71 Female 4/25/2006 United States
Primary
Secondary
Concomitant
Swelling Other Serious 12/1/2004 64 Female 143 lb 5/23/2006 Physician Hungary
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 12/1/2004 55 Female 150 lb 5/23/2006 Physician Hungary
Primary
Secondary
Concomitant
Toothache Other Serious 63 Female 132 lb 5/24/2006 Portugal
Primary
Concomitant
Swelling Other Serious 4/13/2006 51 Female 5/24/2006 Physician Portugal
Primary
Concomitant
Toothache Other Serious 8/1/2005 63 Female 132 lb 6/8/2006 Portugal
Primary
Concomitant
Tooth Loss Other Serious 1/1/2003 60 Female 6/9/2006 United States
Primary
Concomitant
Tooth Extraction Hospitalization 6/20/2005 69 Female 6/26/2006 Physician United Kingdom
Primary
Concomitant
Streptococcal Infection Other Serious 1/7/2004 72 Female 154 lb 6/27/2006 Physician Germany
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2003 61 Female 7/10/2006 Physician Germany
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 8/28/2006 76 Female 158 lb 1/30/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2004 79 Female 152 lb 2/16/2007 Physician Germany
Primary
Concomitant
Pleural Effusion Hospitalization 2/10/2007 57 Female 217 lb 2/12/2007 Physician United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1998 57 Female 150 lb 3/17/2007 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2004 79 Female 152 lb 3/28/2007 Physician Germany
Primary
Concomitant
Stomatitis Other Serious 64 Female 4/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 5/1/2005 74 Female 4/24/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Wound Treatment Other Serious 65 Female 7/31/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 1/1/2001 Female 8/22/2007 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 9/10/2007 66 Female 238 lb 10/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Scleritis Other Serious 9/9/2007 55 Female 130 lb 11/14/2007 Physician United Kingdom
Primary
Secondary
Scleritis Other Serious 9/9/2007 55 Female 130 lb 11/26/2007 United Kingdom
Primary
Concomitant
Pain In Extremity Disability 12/12/2007 60 Female 150 lb 12/28/2007 Physician Germany
Primary
Secondary
Pain In Extremity Disability 12/12/2007 60 Female 150 lb 12/29/2007 Physician Germany
Primary
Secondary
Pain In Extremity Disability 12/12/2007 60 Female 150 lb 2/6/2008 Physician Germany
Primary
Secondary
Pain In Extremity Disability 12/12/2007 60 Female 150 lb 2/6/2008 Physician Germany
Primary
Secondary
Tooth Extraction Other Serious Female 4/21/2008 Other Health Professional Italy
Primary
Concomitant
Tooth Extraction Other Serious Female 4/21/2008 Other Health Professional Italy
Primary
Concomitant
Promotion Of Wound Healing Other Serious Female 4/21/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Stomatitis Hospitalization 5/23/2008 83 Female 7/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Osteoarthritis Other Serious 1/17/2008 69 Female 80 lb 11/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 7/15/2008 Female 12/12/2008 Physician France
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/3/2003 1/13/2009 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 12/1/2008 Female 3/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance Disability Female 4/23/2009 Physician Canada
Primary
Concomitant
Venous Thrombosis Other Serious 1/1/1998 Female 235 lb 5/4/2009 Physician United States
Primary
Concomitant
Vertigo Other Serious 1/1/2004 Female 190 lb 5/11/2009 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/3/2005 Female 154 lb 5/14/2009 Physician United States
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 1/1/1998 Female 235 lb 5/14/2009 Physician United States
Primary
Concomitant
Vertigo Other Serious 1/1/2004 Female 235 lb 6/26/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 2/28/1995 Female 7/20/2009 Other Health Professional United States
Primary
Concomitant
Vertigo Other Serious 1/1/2004 Female 235 lb 7/28/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 8/3/2005 Female 154 lb 10/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/3/2005 Female 154 lb 11/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/28/1995 Female 1/13/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 8/3/2005 Female 154 lb 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/28/1995 Female 136 lb 1/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Other Serious 1/1/2004 Female 235 lb 2/1/2010 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Disability 12/1/2005 Female 2/1/2010 Other Health Professional Italy
Primary
Concomitant
Weight Decreased Other Serious 2/28/1995 Female 136 lb 2/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/28/1995 Female 136 lb 2/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Aplastic Anaemia Other Serious Female 2/5/2010 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Weight Decreased Other Serious 2/28/1995 Female 136 lb 2/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/1/2003 Female 136 lb 2/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/3/2005 Female 154 lb 2/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/3/2005 Female 154 lb 3/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/1/2003 Female 136 lb 3/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Other Serious 1/1/2004 Female 235 lb 3/12/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 8/3/2005 Female 154 lb 3/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/1/2003 Female 136 lb 3/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/19/2003 Female 3/23/2010 United States
Primary
Secondary
Concomitant
Osteonecrosis Disability 11/1/2009 Male 3/24/2010 Physician Romania
Primary
Concomitant
Vertigo Other Serious 1/1/2004 Female 235 lb 3/26/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 7/1/2003 Female 136 lb 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/19/2003 Female 3/26/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/19/2003 Female 3/29/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1998 Female 150 lb 3/31/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/3/2005 Female 154 lb 3/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/1/2003 57 Female 136 lb 4/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/1/2003 57 Female 136 lb 4/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/19/2003 81 Female 4/12/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 4/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/3/2003 46 Female 128 lb 4/16/2010 United States
Primary
Concomitant
Tooth Extraction Other Serious 10/3/2003 46 Female 128 lb 4/22/2010 United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 4/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 4/26/2010 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 11/1/2007 49 Female 4/27/2010 Physician United Kingdom
Primary
Secondary
Weight Decreased Other Serious 6/19/2003 81 Female 5/12/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/19/2003 81 Female 5/18/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 5/20/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/19/2003 81 Female 5/26/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 5/27/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/3/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/19/2003 81 Female 6/3/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/19/2003 81 Female 6/8/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/10/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/19/2003 81 Female 6/11/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/14/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/19/2003 81 Female 6/15/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/19/2003 81 Female 6/16/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/23/2010 United States
Primary
Secondary
Concomitant
Insomnia Hospitalization 12/1/2009 73 Female 6/24/2010 Consumer Venezuela
Primary
Secondary
Concomitant
Vertigo Other Serious 1/1/2004 43 Female 235 lb 7/6/2010 Other Health Professional United States
Primary
Concomitant
Vertigo Other Serious 1/1/2004 53 Female 190 lb 7/7/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 7/7/2010 United States
Primary
Secondary
Concomitant
Vertigo Other Serious 1/1/2004 43 Female 235 lb 7/12/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 8/3/2005 86 Female 154 lb 7/12/2010 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/3/2003 46 Female 128 lb 7/19/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 7/1/2003 57 Female 136 lb 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/15/2008 41 Female 86 lb 7/27/2010 Physician India
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 8/2/2010 United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 1/1/2004 53 Female 190 lb 8/5/2010 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/3/2003 46 Female 128 lb 8/16/2010 United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 10/3/2003 46 Female 128 lb 8/24/2010 United States
Primary
Concomitant
Vertigo Other Serious 1/1/2004 43 Female 235 lb 8/27/2010 United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 10/3/2003 46 Female 128 lb 8/31/2010 United States
Primary
Concomitant
Visual Impairment Other Serious 1/1/2004 53 Female 190 lb 9/8/2010 United States
Primary
Secondary
Concomitant
Open Reduction Of Fracture Other Serious 12/1/2008 64 Female 143 lb 9/22/2010 Physician Japan
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 9/30/2010 United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious Female 10/20/2010 Physician United Kingdom
Primary
Secondary
Visual Impairment Other Serious 1/1/2004 53 Female 190 lb 11/8/2010 United States
Primary
Secondary
Concomitant
Toothache Other Serious 4/16/2009 50 Female 130 lb 11/8/2010 Pharmacist Japan
Primary
Concomitant
Vertebroplasty Other Serious 2/1/2003 51 Female 11/22/2010 Pharmacist United States
Primary
Secondary
Concomitant
Toothache Other Serious 4/16/2009 50 Female 130 lb 11/27/2010 Pharmacist Japan
Primary
Concomitant
Wound Dehiscence Other Serious 10/15/2006 72 Female 12/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Toothache Other Serious 4/16/2009 50 Female 130 lb 12/13/2010 Pharmacist Japan
Primary
Concomitant
Wound Dehiscence Other Serious 10/15/2006 72 Female 12/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Open Reduction Of Fracture Other Serious 12/1/2008 64 Female 143 lb 1/4/2011 Physician Japan
Primary
Secondary
Concomitant
Swelling Death 10/15/2006 72 Female 1/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Back Pain Hospitalization 8/4/2009 67 Female 190 lb 1/28/2011 Physician France
Primary
Secondary
Concomitant
Staphylococcal Skin Infection Other Serious 10/3/2003 46 Female 128 lb 3/9/2011 Other Health Professional United States
Primary
Concomitant
Hypercalcaemia Hospitalization 10/3/2003 46 Female 128 lb 4/5/2011 United States
Primary
Concomitant
Chest Pain Other Serious 8/25/2002 68 Female 4/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Steatosis Other Serious 1/1/2004 53 Female 190 lb 4/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Metastases To Liver Death 3/5/2010 66 Female 121 lb 4/15/2011 Physician Germany
Primary
Concomitant
Disease Progression Other Serious 1/1/2010 31 Female 4/20/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 2/22/2011 82 Female 4/28/2011 Physician Italy
Primary
Secondary
Bone Lesion Other Serious 31 Female 4/21/2011 Physician Denmark
Primary
Secondary
Concomitant
Osteolysis Other Serious 1/1/2006 42 Female 5/5/2011 Other Health Professional United States
Primary
Concomitant
Hypercholesterolaemia Other Serious 8/25/2002 68 Female 5/6/2011 Physician United States
Primary
Secondary
Concomitant
Pain Hospitalization 1/6/2009 69 Female 183 lb 5/9/2011 Physician Germany
Primary
Secondary
Concomitant
Hepatic Neoplasm Death 2/15/2011 61 Female 95 lb 5/16/2011 Physician Germany
Primary
Secondary
Concomitant
Insomnia Other Serious 8/25/2002 68 Female 5/16/2011 Lawyer United States
Primary
Secondary
Concomitant
Macular Hole Other Serious 1/1/2004 53 Female 190 lb 5/20/2011 Lawyer United States
Primary
Secondary
Concomitant
Hepatic Neoplasm Other Serious 2/15/2011 61 Female 95 lb 6/7/2011 Physician Germany
Primary
Secondary
Concomitant
Hypoaesthesia Other Serious 1/1/2006 42 Female 6/10/2011 Physician United States
Primary
Concomitant
Fatigue Other Serious 1/1/2006 42 Female 6/15/2011 Physician United States
Primary
Concomitant
Back Pain Hospitalization 1/6/2009 69 Female 183 lb 6/20/2011 Physician Germany
Primary
Secondary
Concomitant
Abdominal Distension Other Serious 4/1/2002 38 Female 6/30/2011 Physician United States
Primary
Concomitant
Lichenoid Keratosis Other Serious 1/1/2003 56 Female 155 lb 7/7/2011 Pharmacist United States
Primary
Secondary
Concomitant
Ankle Fracture Hospitalization 10/3/2003 46 Female 128 lb 7/20/2011 Physician United States
Primary
Concomitant
Hiatus Hernia Death 10/1/2007 62 Female 136 lb 7/25/2011 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2006 42 Female 7/26/2011 Lawyer United States
Primary
Concomitant
Dizziness Other Serious 8/25/2002 68 Female 8/1/2011 Physician United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 2/1/2003 51 Female 8/4/2011 Pharmacist United States
Primary
Secondary
Concomitant
Excessive Granulation Tissue Hospitalization 1/1/2003 56 Female 155 lb 8/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dysplastic Naevus Other Serious 1/1/2003 56 Female 155 lb 8/11/2011 United States
Primary
Secondary
Concomitant

Drug Data