Tretinoin



Combined with:

Indications and Reactions:

Role Indications Reactions
Primary
Acute Promyelocytic Leukaemia 65.9%
Acute Myeloid Leukaemia 8.6%
Acne 6.4%
Drug Use For Unknown Indication 3.4%
Prophylaxis 2.5%
Product Used For Unknown Indication 1.6%
Skin Hyperpigmentation 1.6%
Antifungal Prophylaxis 1.4%
Myelodysplastic Syndrome 1.4%
Psoriasis 1.4%
Hypertension 0.9%
Alopecia Areata 0.7%
Drug Exposure During Pregnancy 0.7%
Refractory Anaemia 0.7%
Skin Wrinkling 0.7%
Antibiotic Prophylaxis 0.5%
Antibiotic Therapy 0.5%
Chloasma 0.5%
Clostridial Infection 0.5%
Febrile Neutropenia 0.5%
Haemorrhage Intracranial 13.0%
Retinoic Acid Syndrome 12.5%
Sepsis 12.0%
Pulmonary Haemorrhage 7.3%
Cytogenetic Abnormality 6.3%
Pneumonia 5.7%
Myelodysplastic Syndrome 5.2%
Acute Myeloid Leukaemia 4.2%
Death 4.2%
Thrombocytopenia 4.2%
Bacterial Sepsis 3.6%
Malignant Neoplasm Progression 3.6%
Multi-organ Failure 3.6%
Off Label Use 2.6%
Benign Intracranial Hypertension 2.1%
Haemorrhage 2.1%
Neuropathy Peripheral 2.1%
Pyrexia 2.1%
Thermal Burn 2.1%
Hepatic Function Abnormal 1.6%
Secondary
Acute Promyelocytic Leukaemia 42.6%
Acute Myeloid Leukaemia 27.9%
Myelodysplastic Syndrome 7.0%
Neuroblastoma 5.8%
Drug Use For Unknown Indication 2.4%
Acne 1.9%
Product Used For Unknown Indication 1.6%
Antibiotic Therapy 1.3%
Psoriasis 1.1%
Antifungal Prophylaxis 1.0%
Alopecia 0.9%
Cellulitis 0.9%
Chemotherapy 0.9%
Dermatitis 0.9%
Hypertension 0.7%
Pyrexia 0.7%
Febrile Neutropenia 0.6%
Pneumonia 0.6%
Prophylaxis 0.6%
Erythroleukaemia 0.5%
Acute Myeloid Leukaemia 15.4%
Pneumonia 8.3%
Sepsis 8.3%
Chronic Myelomonocytic Leukaemia 7.7%
Hyperbilirubinaemia 7.1%
Multi-organ Failure 6.4%
Myelodysplastic Syndrome 5.8%
Pyrexia 5.1%
Bacterial Sepsis 4.5%
Febrile Neutropenia 4.5%
Pregnancy 3.2%
Retinoic Acid Syndrome 3.2%
Alanine Aminotransferase Increased 2.6%
Cytogenetic Abnormality 2.6%
Death 2.6%
Malignant Neoplasm Progression 2.6%
Pain 2.6%
Pulmonary Embolism 2.6%
Renal Failure Acute 2.6%
Venoocclusive Liver Disease 2.6%
Concomitant
Acne 17.4%
Product Used For Unknown Indication 13.2%
Acute Myeloid Leukaemia 11.3%
Acute Promyelocytic Leukaemia 9.5%
Contraception 6.4%
Prophylaxis 6.1%
Hypertension 5.1%
Drug Use For Unknown Indication 4.4%
Depression 3.5%
Osteoporosis 3.1%
Psoriasis 2.8%
Pyrexia 2.7%
Asthma 2.6%
Rheumatoid Arthritis 2.0%
Infection Prophylaxis 1.8%
Prophylaxis Of Nausea And Vomiting 1.8%
Anxiety 1.7%
Pain 1.6%
Abdominal Pain 1.5%
Gastrooesophageal Reflux Disease 1.5%
Vomiting 9.9%
Deep Vein Thrombosis 7.4%
Weight Increased 7.4%
Pain 6.6%
Gallbladder Disorder 5.8%
Tooth Extraction 5.8%
Drug Ineffective 5.0%
Nausea 5.0%
Pulmonary Embolism 5.0%
Vascular Graft Occlusion 5.0%
Ventricular Tachycardia 5.0%
Vitreous Haemorrhage 5.0%
Syncope 4.1%
Viral Infection 4.1%
Renal Failure Acute 3.3%
Sepsis 3.3%
Thrombophlebitis Superficial 3.3%
Vision Blurred 3.3%
Weight Decreased 3.3%
Abdominal Pain 2.5%
Interacting
Acute Promyelocytic Leukaemia 59.7%
Antifungal Prophylaxis 14.5%
Drug Use For Unknown Indication 6.5%
Prophylaxis 4.8%
Staphylococcal Infection 4.8%
Anaemia 3.2%
Febrile Neutropenia 3.2%
Thrombocytopenia 3.2%
Retinoic Acid Syndrome 20.8%
Renal Failure Acute 16.7%
Benign Intracranial Hypertension 8.3%
Multi-organ Failure 8.3%
Renal Disorder 8.3%
Renal Impairment 8.3%
Vomiting 8.3%
Abdominal Distension 4.2%
Blood Bilirubin Increased 4.2%
Metabolic Acidosis 4.2%
Pneumonia Klebsiella 4.2%
Septic Shock 4.2%