Cytarabine combined with Tretinoin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Memory Impairment Other Serious 52 Male 6/30/2006
Primary
Secondary
White Blood Cell Count Decreased Life Threatening 12/28/2005 58 Male 7/20/2006 Japan
Primary
Concomitant
Splenic Infarction Other Serious 34 Female 9/1/2006 United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 4 Male 8/3/2007 Canada
Primary
Secondary
Concomitant
Haemorrhage Intracranial Hospitalization 10/1/1999 69 Male 12/18/2007 Pharmacist Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious Female 1/28/2008
Primary
Secondary
Retinoic Acid Syndrome Other Serious 78 Female 1/21/2008 Physician United States
Primary
Concomitant
Splenic Abscess Other Serious 15 Male 2/28/2008 Other Health Professional Turkey
Primary
Secondary
Concomitant
Thrombocytopenia Death 2/29/2008 Physician China
Primary
Secondary
Streptococcal Infection Life Threatening 44 Male 5/23/2008 Other Health Professional France
Primary
Secondary
Concomitant
Hypercalcaemia Other Serious 24 Male 8/4/2008 Japan
Primary
Concomitant
Interacting
Renal Failure Acute Other Serious 8/5/2008 Other Health Professional Turkey
Primary
Secondary
Concomitant
Haemorrhage Death 12/19/2008 Other Health Professional Tunisia
Primary
Secondary
Haemorrhage Death 12/19/2008 Physician Tunisia
Primary
Secondary
Haemorrhage Death 12/19/2008 Physician Tunisia
Primary
Secondary
Haemorrhage Intracranial Death 1/12/2009 Other Health Professional China
Primary
Secondary
Haemorrhage Intracranial Death 1/12/2009 Other Health Professional China
Primary
Secondary
Oesophageal Stenosis Other Serious 16 Male 4/30/2009 Canada
Primary
Secondary
Leukaemia Recurrent Other Serious 8/1/2006 Female 5/11/2009 Other Health Professional China
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 65 Male 8/4/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Osteomyelitis Other Serious 32 Male 8/4/2009 Physician Puerto Rico
Primary
Secondary
Tachycardia Hospitalization 8/29/2009 Female 168 lb 9/8/2009 United States
Primary
Secondary
Bacterial Sepsis Death 9/28/2009 Physician China
Primary
Secondary
Bacterial Sepsis Other Serious 9/28/2009 Physician China
Primary
Secondary
Bacterial Sepsis Other Serious 9/28/2009 Physician China
Primary
Secondary
Bacterial Sepsis Other Serious 9/28/2009 Physician China
Primary
Secondary
Bacterial Sepsis Other Serious 9/28/2009 Physician China
Primary
Secondary
Bacterial Sepsis Other Serious 9/28/2009 Physician China
Primary
Secondary
Bacterial Sepsis Other Serious 9/28/2009 Physician China
Primary
Secondary
Acute Febrile Neutrophilic Dermatosis Other Serious 49 Female 11/30/2009 Other Health Professional China
Primary
Secondary
Acute Febrile Neutrophilic Dermatosis Other Serious 49 Female 12/7/2009 Other Health Professional China
Primary
Secondary
Pain In Extremity 12/12/2009 Male 196 lb 12/15/2009 United States
Primary
Secondary
Pyrexia 12/8/2009 Female 153 lb 12/14/2009 United States
Primary
Secondary
Peroneal Nerve Palsy Other Serious 51 Female 1/8/2010 Other Health Professional United States
Primary
Secondary
Muscular Weakness Hospitalization 1/4/2009 Female 153 lb 1/4/2010 United States
Primary
Secondary
Retinoic Acid Syndrome Hospitalization 1/21/2010 Male 167 lb 2/9/2010 United States
Primary
Secondary
Concomitant
Cytogenetic Abnormality Other Serious 20 Male 2/19/2010 Other Health Professional Australia
Primary
Secondary
Thrombocytopenia Other Serious 13 Male 3/10/2010 Physician Austria
Primary
Secondary
Thrombocytopenia Other Serious 13 Male 3/10/2010 Physician Austria
Primary
Secondary
Neutrophil Count Abnormal Hospitalization 3/13/2010 Male 196 lb 3/15/2010 United States
Primary
Secondary
Neutrophil Count Decreased Hospitalization 3/13/2010 Male 196 lb 3/18/2010 United States
Primary
Secondary
Swelling Hospitalization 4/4/2010 34 Male 163 lb 4/5/2010 United States
Primary
Secondary
Pyrexia Hospitalization 4/1/2010 7 Male 63 lb 4/28/2010 United States
Primary
Secondary
Renal Impairment Other Serious 25 Male 9/1/2010 Other Health Professional Japan
Primary
Concomitant
Interacting
Vomiting Other Serious 48 Male 9/1/2010 Other Health Professional Japan
Primary
Concomitant
Interacting
Renal Impairment Other Serious 25 Male 9/7/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 48 Male 9/7/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 25 Male 9/21/2010 Other Health Professional Japan
Primary
Concomitant
Interacting
Vomiting Other Serious 48 Male 9/21/2010 Other Health Professional Japan
Primary
Concomitant
Interacting
Chronic Myelomonocytic Leukaemia Other Serious 60 Male 10/19/2010 Physician Japan
Primary
Secondary
Chronic Myelomonocytic Leukaemia Other Serious 60 Male 10/20/2010 Physician Japan
Primary
Secondary
Sinus Tachycardia Hospitalization 10/14/2010 3 Male 29 lb 10/18/2010 United States
Primary
Secondary
Renal Cell Carcinoma Other Serious 58 Male 11/17/2010 Other Health Professional United States
Primary
Secondary
Renal Cell Carcinoma Other Serious 58 Male 11/24/2010 Physician United States
Primary
Secondary
Venoocclusive Liver Disease Hospitalization 1/20/2011 52 Male 190 lb 2/25/2011 Physician Germany
Primary
Secondary
Concomitant
Metabolic Acidosis Life Threatening 3/6/2011 52 Female 196 lb 4/1/2011 Physician Germany
Primary
Secondary
Concomitant
Sepsis Life Threatening 3/6/2011 52 Female 196 lb 4/1/2011 Physician Germany
Primary
Secondary
Concomitant
Sepsis Life Threatening 3/6/2011 52 Female 196 lb 4/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatitis Toxic Death 3/14/2011 57 Male 205 lb 4/5/2011 Physician Germany
Primary
Secondary
Sepsis Death 3/6/2011 52 Female 196 lb 4/7/2011 Physician Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/17/2011 Female 108 lb 4/8/2011 Physician United States
Primary
Secondary
Hepatitis Toxic Death 3/14/2011 57 Male 205 lb 4/8/2011 Physician Germany
Primary
Secondary
Sepsis Life Threatening 3/6/2011 52 Female 196 lb 4/15/2011 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 3/6/2011 52 Female 196 lb 4/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 3/17/2011 Female 108 lb 4/15/2011 Physician United States
Primary
Secondary
Sepsis Life Threatening 3/6/2011 52 Female 196 lb 4/18/2011 Physician Germany
Primary
Secondary
Concomitant
Sepsis Life Threatening 3/14/2011 57 Male 205 lb 4/19/2011 Other Health Professional United States
Primary
Secondary
Condition Aggravated Hospitalization 12/1/2010 33 Male 4/22/2011 Other Health Professional France
Primary
Secondary
Concomitant
Sepsis Death 3/14/2011 57 Male 205 lb 5/3/2011 Physician Germany
Primary
Secondary
Acute Promyelocytic Leukaemia Differentiation Syndrome Death 6/6/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Pancytopenia Death 62 Female 6/16/2011 Other Health Professional Turkey
Primary
Secondary
Hyperbilirubinaemia Other Serious 5/24/2011 42 Female 198 lb 6/23/2011 Physician Germany
Primary
Secondary
Hepatitis B Death 9/1/2007 62 Female 6/23/2011 Other Health Professional Turkey
Primary
Secondary
Acute Promyelocytic Leukaemia Other Serious 39 Male 6/27/2011 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Pancytopenia Death 62 Female 6/22/2011 Turkey
Primary
Secondary
Anal Infection Hospitalization 6/27/2011 64 Female 148 lb 8/4/2011 Physician United States
Primary
Secondary
Concomitant
Hypercalcaemia Other Serious 25 Male 8/5/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Infection Hospitalization 6/8/2011 61 Female 8/12/2011 Physician Germany
Primary
Secondary
Sepsis Death 8/7/2011 Female 251 lb 8/19/2011 Physician United States
Primary
Secondary
Hyperbilirubinaemia Other Serious 5/24/2011 42 Female 198 lb 8/26/2011 Physician Germany
Primary
Secondary
Sepsis Death 7/4/2011 65 Male 165 lb 9/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperbilirubinaemia Other Serious 5/24/2011 42 Female 198 lb 9/15/2011 Physician United States
Primary
Secondary
Sepsis Death 3/14/2011 57 Male 205 lb 9/15/2011 Other Health Professional United States
Primary
Secondary
Fatigue Hospitalization 6/8/2011 61 Female 143 lb 9/19/2011 Physician Germany
Primary
Secondary
Respiratory Distress Hospitalization 9/13/2011 12 Female 172 lb 9/27/2011 Physician United States
Primary
Secondary
Peroneal Nerve Palsy Other Serious 6/24/2011 56 Female 126 lb 10/27/2011 Physician Germany
Primary
Secondary
Venoocclusive Liver Disease Other Serious 9/27/2011 68 Female 220 lb 11/2/2011 Consumer United States
Primary
Secondary
Blood Culture Positive Hospitalization 11/7/2011 16 Female 123 lb 11/11/2011 Physician United States
Primary
Secondary
Pyrexia Hospitalization 11/10/2011 10 Male 96 lb 11/13/2011 United States
Primary
Secondary
Inflammation Hospitalization 9/22/2011 16 Male 230 lb 11/15/2011 United States
Primary
Secondary
Escherichia Infection Hospitalization 11/7/2011 Female 123 lb 11/18/2011 Physician United States
Primary
Secondary
Pyrexia Other Serious 36 Male 12/14/2011 Physician Iran (Islamic Republic Of)
Primary
Concomitant
Mouth Ulceration Other Serious 36 Male 12/14/2011 Physician Iran (Islamic Republic Of)
Primary
Concomitant
Blood Culture Positive Hospitalization 11/7/2011 16 Female 123 lb 12/20/2011 United States
Primary
Secondary
Multi-organ Failure Death 9/27/2011 68 Female 220 lb 12/26/2011 Consumer United States
Primary
Secondary
Febrile Neutropenia Hospitalization 11/7/2011 Female 123 lb 12/28/2011 Physician United States
Primary
Secondary
Anal Infection Hospitalization 6/27/2011 64 Female 148 lb 1/9/2012 Physician United States
Primary
Secondary
Concomitant
Mitral Valve Incompetence Hospitalization 1/25/2011 25 Female 2/2/2012 Physician France
Primary
Secondary
Concomitant
Neutropenia Hospitalization 9/27/2011 68 Female 220 lb 2/3/2012 Consumer United States
Primary
Secondary
Eosinophilia Other Serious 61 Male 2/7/2012 Other Health Professional France
Primary
Secondary
Concomitant
Enterococcal Sepsis Hospitalization 65 Female 2/9/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Hyperbilirubinaemia Other Serious 5/24/2011 42 Female 198 lb 2/16/2012 Physician Germany
Primary
Secondary
Neoplasm Death 46 Male 2/17/2012 Korea, Republic Of
Primary
Secondary
Neutrophil Count Decreased Hospitalization 2/15/2012 7 Male 47 lb 2/22/2012 Physician United States
Primary
Secondary
Enterococcal Sepsis Hospitalization 65 Female 2/17/2012 Germany
Primary
Secondary
Oliguria Hospitalization 47 Male 3/3/2012 Other Health Professional Brazil
Primary
Secondary
Concomitant
Respiratory Tract Haemorrhage Other Serious 47 Female 3/7/2012 Other Health Professional Brazil
Primary
Secondary
Concomitant
Neutropenic Colitis Death 10/1/2011 45 Female 181 lb 3/8/2012 Consumer United States
Primary
Secondary
Concomitant
Retinoic Acid Syndrome Other Serious 3 Male 3/9/2012 United States
Primary
Concomitant
Pneumonia Klebsiella Hospitalization 47 Female 152 lb 3/9/2012 Other Health Professional Brazil
Primary
Secondary
Concomitant
Interacting
Leukocytosis Hospitalization 3/1/2009 61 Male 3/21/2012 Other Health Professional France
Primary
Secondary
Chronic Myelomonocytic Leukaemia Hospitalization 3/1/2009 70 Male 3/22/2012 Other Health Professional France
Primary
Secondary
Chronic Myelomonocytic Leukaemia Hospitalization 3/1/2009 70 Male 3/22/2012 Other Health Professional France
Primary
Secondary
Chronic Myelomonocytic Leukaemia Hospitalization 3/1/2009 70 Male 3/22/2012 Other Health Professional France
Primary
Secondary
Chronic Myelomonocytic Leukaemia Hospitalization 3/1/2009 70 Male 3/22/2012 Other Health Professional France
Primary
Secondary
Chronic Myelomonocytic Leukaemia Hospitalization 3/1/2009 70 Male 3/28/2012 Other Health Professional France
Primary
Secondary
Bronchitis Hospitalization 4/4/2011 55 Male 212 lb 4/5/2012 Physician Germany
Primary
Secondary
Concomitant
Chronic Myelomonocytic Leukaemia Other Serious Male 3/29/2012 France
Primary
Secondary
Concomitant
Neoplasm Death 46 Male 4/11/2012 Korea, Republic Of
Primary
Secondary
Weight Increased Other Serious 47 Male 4/13/2012 Other Health Professional Brazil
Primary
Secondary
Concomitant
Bronchitis Hospitalization 4/4/2011 55 Male 212 lb 4/19/2012 Physician Germany
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/20/2012 Physician United States
Primary
Secondary
Thrombocytopenia Death 4/20/2012 Physician United States
Primary
Secondary
Pulmonary Haemorrhage Other Serious 4/20/2012 Physician United States
Primary
Secondary
Hypersensitivity Hospitalization 10/8/2011 70 Female 143 lb 4/23/2012 Physician Germany
Primary
Secondary
Concomitant
Haematotoxicity Other Serious 4/24/2012 Physician United States
Primary
Secondary
Lip Swelling Hospitalization 10/8/2011 70 Female 143 lb 5/8/2012 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 31 Male 5/10/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 52 Female 5/22/2012 United States
Primary
Secondary
Tricuspid Valve Incompetence Hospitalization 5/9/2012 5 Female 47 lb 5/22/2012 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 5/7/2012 5 Female 47 lb 5/29/2012 Physician United States
Primary
Secondary
Respiratory Tract Haemorrhage Death 47 Female 150 lb 5/30/2012 Other Health Professional Brazil
Primary
Secondary
Concomitant
Bronchitis Hospitalization 4/4/2011 55 Male 212 lb 5/30/2012 Physician Germany
Primary
Secondary
Concomitant
Post Procedural Complication Death 49 Male 5/25/2012 Physician United States
Primary
Secondary
Multi-organ Failure Other Serious 52 Female 5/25/2012 Physician United States
Primary
Secondary
Lip Swelling Hospitalization 10/8/2011 70 Female 143 lb 6/7/2012 Physician Germany
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 5/9/2012 5 Female 47 lb 6/5/2012 Physician United States
Primary
Secondary
Multi-organ Failure Other Serious 9/27/2011 68 Female 220 lb 6/25/2012 Consumer United States
Primary
Secondary
Pneumonia Other Serious 6/25/2012 44 Male 176 lb 7/5/2012 Physician Germany
Primary
Secondary
Renal Failure Acute Hospitalization 10/8/2011 70 Female 143 lb 7/5/2012 Physician Germany
Primary
Secondary
Concomitant
Multi-organ Failure Death 52 Female 7/17/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Oesophageal Mass Death 60 Female 7/18/2012 Physician United States
Primary
Secondary
Multi-organ Failure Death 60 Female 7/18/2012 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Death 60 Female 7/18/2012 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Death 60 Female 7/18/2012 Physician United States
Primary
Secondary
Treatment Related Secondary Malignancy Death 60 Male 7/18/2012 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Death 60 Male 7/18/2012 Physician United States
Primary
Secondary
Acute Myeloid Leukaemia Death 60 Male 7/18/2012 Physician United States
Primary
Secondary
Acute Myeloid Leukaemia Death 60 Male 7/18/2012 Physician United States
Primary
Secondary
Pneumonia Other Serious 6/25/2012 44 Male 176 lb 7/19/2012 Physician Germany
Primary
Secondary

Drug Data