Ciclosporin



Indications and Reactions:

Role Indications Reactions
Primary
Prophylaxis Against Graft Versus Host Disease 25.1%
Renal Transplant 14.1%
Immunosuppression 10.4%
Immunosuppressant Drug Therapy 5.4%
Nephrotic Syndrome 5.4%
Graft Versus Host Disease 5.1%
Surgical Preconditioning 5.1%
Prophylaxis 3.8%
Stem Cell Transplant 3.5%
Histiocytosis Haematophagic 2.7%
Prophylaxis Against Transplant Rejection 2.4%
Interstitial Lung Disease 2.3%
Bone Marrow Transplant 2.0%
Aplastic Anaemia 2.0%
Heart Transplant 1.9%
Acute Lymphocytic Leukaemia 1.9%
Bone Marrow Conditioning Regimen 1.7%
Infection Prophylaxis 1.7%
Liver Transplant 1.7%
Psoriasis 1.7%
Toxicity To Various Agents 12.3%
Thrombotic Microangiopathy 8.5%
Renal Impairment 8.0%
Sepsis 7.1%
Malignant Neoplasm Progression 6.1%
Graft Versus Host Disease 5.7%
Pyrexia 5.7%
Respiratory Failure 5.7%
Interstitial Lung Disease 5.2%
Vomiting 4.7%
Infection 3.8%
Renal Failure Acute 3.3%
Transplant Rejection 3.3%
Venoocclusive Disease 3.3%
Zygomycosis 3.3%
Drug Ineffective 2.8%
Multi-organ Failure 2.8%
Natural Killer Cell Count Increased 2.8%
Renal Failure 2.8%
Rhabdomyolysis 2.8%
Secondary
Prophylaxis Against Renal Transplant Rejection 14.9%
Product Used For Unknown Indication 14.1%
Renal Transplant 11.0%
Prophylaxis Against Transplant Rejection 9.2%
Heart Transplant 8.8%
Prophylaxis Against Graft Versus Host Disease 6.9%
Immunosuppression 5.9%
Prophylaxis 5.6%
Hypertension 3.7%
Infection Prophylaxis 3.0%
Bone Marrow Conditioning Regimen 2.3%
Surgical Preconditioning 2.1%
Acute Myeloid Leukaemia 1.9%
Immunosuppressant Drug Therapy 1.9%
Aplastic Anaemia 1.7%
Rheumatoid Arthritis 1.7%
Stem Cell Transplant 1.5%
Histiocytosis Haematophagic 1.4%
Osteoporosis 1.3%
Pustular Psoriasis 1.2%
Metastases To Liver 15.0%
Ureteric Stenosis 11.2%
Osteonecrosis 9.7%
Vomiting 6.4%
Sepsis 5.6%
Urinary Tract Infection 4.5%
Pancytopenia 4.1%
Renal Failure Acute 4.1%
Tendon Rupture 4.1%
Malignant Neoplasm Progression 3.7%
Renal Impairment 3.7%
Blood Creatinine Increased 3.4%
Pyrexia 3.4%
Urinary Tract Infection Pseudomonal 3.4%
Venoocclusive Disease 3.4%
Venoocclusive Liver Disease 3.4%
Transplant Failure 3.0%
Death 2.6%
Rhabdomyolysis 2.6%
Thrombotic Microangiopathy 2.6%
Concomitant
Prophylaxis 22.1%
Aplastic Anaemia 17.1%
Product Used For Unknown Indication 11.6%
Infection Prophylaxis 10.1%
Prophylaxis Against Gastrointestinal Ulcer 4.2%
Antiviral Prophylaxis 3.5%
Hypertension 3.5%
Prophylaxis Against Graft Versus Host Disease 3.0%
Constipation 2.9%
Premedication 2.8%
Bone Marrow Conditioning Regimen 2.6%
Rheumatoid Arthritis 2.5%
Acute Lymphocytic Leukaemia 2.4%
Psoriasis 2.2%
Anxiety Disorder 2.1%
Insomnia 1.8%
Antifungal Prophylaxis 1.6%
Immunosuppression 1.5%
Pain 1.3%
Prophylaxis Against Transplant Rejection 1.2%
White Blood Cell Count Decreased 14.5%
Pneumonia 9.6%
Rotavirus Infection 7.2%
Pyrexia 6.6%
Renal Impairment 6.0%
Thrombotic Microangiopathy 5.4%
Vomiting 5.4%
Venoocclusive Liver Disease 4.8%
Viral Haemorrhagic Cystitis 4.2%
Colitis Ulcerative 3.6%
Death 3.6%
Nephrotic Syndrome 3.6%
Off Label Use 3.6%
Stomatitis 3.6%
Visual Impairment 3.6%
Febrile Neutropenia 3.0%
Infection 3.0%
Therapeutic Response Decreased 3.0%
Venoocclusive Disease 3.0%
Gastric Ulcer 2.4%
Interacting
Product Used For Unknown Indication 19.7%
Antibiotic Prophylaxis 8.5%
Hiv Infection 6.4%
Still's Disease Adult Onset 6.4%
Immunosuppressant Drug Therapy 5.9%
Coronary Artery Disease 5.3%
Immunosuppression 5.3%
Antiretroviral Therapy 4.8%
Gout 4.3%
Vulvovaginal Candidiasis 3.7%
Bronchiolitis 3.2%
Glomerulonephritis Minimal Lesion 3.2%
Graft Versus Host Disease 3.2%
Heart And Lung Transplant 3.2%
Liver Transplant 3.2%
Nephrotic Syndrome 3.2%
Prophylaxis 3.2%
Tuberculosis 3.2%
Anticoagulant Therapy 2.1%
Aspergillus Infection 2.1%
Immunosuppressant Drug Level Increased 16.3%
Haemorrhage 9.3%
Therapeutic Response Decreased 9.3%
Haemoglobin Decreased 7.0%
Hepatotoxicity 7.0%
International Normalised Ratio Increased 7.0%
Immunosuppressant Drug Level Decreased 4.7%
Renal Impairment 4.7%
Rhabdomyolysis 4.7%
Toxicity To Various Agents 4.7%
Vision Blurred 4.7%
Cytolytic Hepatitis 2.3%
Drug Interaction 2.3%
Drug Level Increased 2.3%
Drug Therapeutic Incompatibility 2.3%
Multi-organ Failure 2.3%
Productive Cough 2.3%
Renal Failure 2.3%
Serum Ferritin Decreased 2.3%
White Blood Cell Count Increased 2.3%