Ciclosporin combined with Cyclophosphamide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombotic Microangiopathy Other Serious 8/10/2007 30 Female 9/20/2007 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 44 Male 10/5/2007 Other Health Professional Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 13 Male 101 lb 10/12/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 28 Male 10/15/2007 Consumer Switzerland
Primary
Secondary
Ureaplasma Infection Other Serious 28 Male 10/15/2007 Switzerland
Primary
Secondary
Concomitant
Immunosuppression Other Serious 4/19/2007 7 Female 10/16/2007 Consumer Greece
Primary
Secondary
Concomitant
Venoocclusive Disease Death 4/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Liver Disorder Other Serious 1/1/2009 59 Female 7/6/2009 Other Health Professional Japan
Primary
Concomitant
Renal Failure Other Serious 38 Male 7/31/2009 Other Health Professional Australia
Primary
Concomitant
Splenomegaly Other Serious 23 Male 7/12/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Testicular Swelling Other Serious 22 Male 7/13/2010 Other Health Professional Iran (Islamic Republic Of)
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 2 Male 7/19/2010 Other Health Professional Japan
Primary
Concomitant
Pyrexia Other Serious 2/16/2009 23 Male 161 lb 7/20/2010 Other Health Professional Japan
Primary
Concomitant
Visual Impairment Other Serious 3/11/2009 49 Female 84 lb 7/21/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 9/26/2010 28 Female 3/1/2011 Physician Australia
Primary
Secondary
Concomitant
Autoimmune Thrombocytopenia Death 3/2/2011 Physician Mexico
Primary
Secondary
Concomitant
Immunotactoid Glomerulonephritis Other Serious 58 Male 3/3/2011 Other Health Professional Japan
Primary
Concomitant
Pyrexia Other Serious 2/16/2009 24 Male 161 lb 12/18/2012 Other Health Professional Jp
Primary
Concomitant
Ventricular Arrhythmia Hospitalization 12/17/2009 14 Female 97 lb 3/28/2013 Physician Jp
Primary
Secondary
Concomitant
Viral Haemorrhagic Cystitis Other Serious 8/17/2010 16 Female 121 lb 1/15/2013 Physician Jp
Primary
Secondary
Concomitant
Stomatitis Life Threatening 9/27/2010 60 Male 151 lb 9/12/2012 Physician Jp
Primary
Concomitant
Pyrexia Death 10/16/2009 38 Female 110 lb 12/6/2012 Physician Jp
Primary
Secondary
Concomitant
Venoocclusive Disease Death 8 Female 49 lb 6/27/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Staphylococcal Sepsis Life Threatening 5/20/2011 34 Female 132 lb 9/13/2012 Physician Jp
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Other Serious 6/8/2011 48 Female 84 lb 12/12/2012 Physician Jp
Primary
Secondary
Concomitant
Sepsis Other Serious 10/12/2010 6 Female 62 lb 12/21/2012 Physician Jp
Primary
Concomitant
Graft Versus Host Disease Death 4/20/2011 30 Female 106 lb 9/10/2012 Physician Jp
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 12/8/2011 Female 12/10/2012 Physician Jp
Primary
Secondary
Concomitant
Post Transplant Lymphoproliferative Disorder Death 2012 5 Female 44 lb 10/24/2012 Other Health Professional Es
Primary
Secondary
Pancytopenia Life Threatening 8/2011 Male 126 lb 9/25/2012 Physician Jp
Primary
Secondary
Concomitant
Respiratory Disorder Death 71 Female 8/28/2012 Other Health Professional Jp
Primary
Secondary
Streptococcal Infection Hospitalization 9 Male 60 lb 9/12/2012 Other Health Professional Pl
Primary
Secondary
Concomitant
Off Label Use Death 9/12/2012 Other Health Professional Ca
Primary
Secondary
Concomitant
Venoocclusive Disease Death 9/13/2012 Other Health Professional Ca
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Death 46 Female 8/31/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Viral Infection Death 11 Male 8/31/2012 Other Health Professional Hk
Primary
Secondary
Concomitant
Viral Infection Other Serious 1 Female 8/31/2012 Other Health Professional Hk
Primary
Secondary
Concomitant
Wernicke's Encephalopathy Other Serious 12 Male 9/4/2012 Other Health Professional Kr
Primary
Concomitant
Off Label Use Death 9/13/2012 Other Health Professional Ca
Primary
Secondary
Concomitant
Respiratory Failure Death 9 Female 9/4/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Viral Infection Other Serious 1 Male 9/5/2012 Other Health Professional Hk
Primary
Secondary
Concomitant
Fungal Sepsis Death 9/6/2012 Other Health Professional Ie
Primary
Concomitant
Growth Retardation Other Serious 0 Male 9/6/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Venoocclusive Disease Death 9/7/2012 Other Health Professional Ie
Primary
Secondary
Concomitant
Vomiting Other Serious 18 Male 9/7/2012 Other Health Professional Br
Primary
Secondary
Concomitant
Neoplasm Recurrence Other Serious 9/18/2012 Other Health Professional Ie
Primary
Secondary
Concomitant
Juvenile Chronic Myelomonocytic Leukaemia Death 9/7/2012 Other Health Professional Ie
Primary
Concomitant
Respiratory Failure Other Serious 60 Male 9/8/2012 Other Health Professional Ua
Primary
Secondary
Sepsis Death 2 9/12/2012 Other Health Professional It
Primary
Secondary
Bacterial Sepsis Death 9/13/2012 Other Health Professional Ie
Primary
Concomitant
Multi-organ Failure Death 10/1/2012 Other Health Professional Cn
Primary
Secondary
Concomitant
Leukaemia Recurrent Death 10/1/2012 Other Health Professional Cn
Primary
Concomitant
Klebsiella Infection Other Serious 1 9/17/2012 Other Health Professional Gb
Primary
Secondary
Putamen Haemorrhage Other Serious NotSpecified 4/8/2013 Other Health Professional Jp
Primary
Secondary
Venoocclusive Disease Other Serious 0 9/21/2012 Other Health Professional Gb
Primary
Secondary
Mucosal Inflammation Other Serious 0 9/21/2012 Other Health Professional Gb
Primary
Secondary
Staphylococcal Infection Other Serious 0 9/21/2012 Other Health Professional Gb
Primary
Secondary
Sepsis Death 40 Female 9/24/2012 Physician De
Primary
Secondary
Pneumonia Death 37 Male 9/24/2012 Physician De
Primary
Secondary
Tremor Other Serious 15 Female 11/5/2012 Other Health Professional De
Primary
Concomitant
Vomiting Other Serious 7 Female 9/27/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Transplant Rejection Death 3 Male 9/27/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Neutropenia Other Serious Male 9/27/2012 Other Health Professional No
Primary
Secondary
Concomitant
Swelling Face Other Serious 2 Female 9/26/2012 Physician Jp
Primary
Secondary
Concomitant
Hepatic Vein Occlusion Other Serious 10/4/2012 Other Health Professional Cn
Primary
Concomitant
Transplant Rejection Death 8 Male 10/8/2012 Other Health Professional Cn
Primary
Secondary
Transplant Rejection Other Serious 4 Male 10/8/2012 Other Health Professional Cn
Primary
Secondary
Weight Increased Other Serious 2 Female 10/12/2012 Other Health Professional Cn
Primary
Secondary
Transplant Rejection Other Serious 1 Female 10/12/2012 Other Health Professional Cn
Primary
Secondary
Transplant Failure Other Serious 5 Female 10/12/2012 Other Health Professional Cn
Primary
Secondary
Pyrexia Life Threatening 3/19/2009 36 Male 179 lb 10/12/2012 Physician Jp
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 5 Male 10/12/2012 Other Health Professional Cn
Primary
Secondary
Transplant Failure Other Serious 8 Female 10/12/2012 Other Health Professional Cn
Primary
Secondary
Pulmonary Haemorrhage Death 7 Male 10/12/2012 Other Health Professional Cn
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 3 Male 10/12/2012 Other Health Professional Cn
Primary
Secondary
Rash Maculo-papular Other Serious 3 Male 10/12/2012 Other Health Professional Cn
Primary
Secondary
Leukoencephalopathy Death 10/16/2012 Other Health Professional Cn
Primary
Concomitant
Interstitial Lung Disease Death 10/16/2012 Other Health Professional Cn
Primary
Concomitant
Transaminases Increased Other Serious 33 Male 10/16/2012 Other Health Professional Cn
Primary
Concomitant
Organ Failure Death 30 Male 10/17/2012 Other Health Professional Cn
Primary
Concomitant
Interstitial Lung Disease Other Serious 9 Male 64 lb 10/17/2012 Other Health Professional Cn
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 6 Male 49 lb 10/17/2012 Other Health Professional Cn
Primary
Secondary
Concomitant
Thalassaemia Beta Other Serious 7 Male 49 lb 10/17/2012 Other Health Professional Cn
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Other Serious 24 Male 10/19/2012 Other Health Professional Cn
Primary
Concomitant
Graft Versus Host Disease In Skin Other Serious 24 Male 10/19/2012 Other Health Professional Cn
Primary
Secondary
Concomitant
Engraft Failure Other Serious 10/19/2012 Other Health Professional Cn
Primary
Secondary
Concomitant
Death Death 33 Female 10/24/2012 Other Health Professional Cn
Primary
Concomitant
Pneumonia Legionella Death 10/25/2012 Other Health Professional It
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 10/26/2012 Other Health Professional It
Primary
Concomitant
Pericarditis Other Serious 10/26/2012 Other Health Professional It
Primary
Concomitant
Nephrotic Syndrome Other Serious 31 Female 10/26/2012 Other Health Professional Jp
Primary
Concomitant
Tuberculosis Death 20 Female 10/23/2012 Other Health Professional Cn
Primary
Concomitant
Interstitial Lung Disease Death 43 Male 10/23/2012 Other Health Professional Cn
Primary
Concomitant
Renal Impairment Hospitalization 2 Male 11/3/2012 Other Health Professional Sa
Primary
Concomitant
Venoocclusive Disease Hospitalization 1/25/2011 3 Male 35 lb 10/10/2012 Gb
Primary
Secondary
Concomitant
Renal Impairment Death 2 Male 11/5/2012 Other Health Professional Sa
Primary
Concomitant
Respiratory Failure Death 69 Male 11/7/2012 Other Health Professional Jp
Primary
Concomitant
Respiratory Failure Death 63 Male 11/7/2012 Other Health Professional Jp
Primary
Concomitant
Respiratory Failure Death 67 Female 11/7/2012 Other Health Professional Jp
Primary
Concomitant
Ureteric Stenosis Other Serious 20 Male 11/7/2012 Other Health Professional Cn
Primary
Concomitant
Death Death 11/11/2012 Other Health Professional Cn
Primary
Concomitant
Venoocclusive Disease Death 11/11/2012 Other Health Professional Cn
Primary
Concomitant
Venoocclusive Disease Death 11/11/2012 Other Health Professional Cn
Primary
Concomitant
Infection Death 11/11/2012 Other Health Professional Cn
Primary
Concomitant
Infection Death 11/11/2012 Other Health Professional Cn
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 15 11/19/2012 Other Health Professional Ru
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 12 Male 11/19/2012 Other Health Professional Ru
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Death 39 Female 12/26/2012 Other Health Professional It
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 23 Male 12/26/2012 Other Health Professional It
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 45 Female 12/26/2012 Other Health Professional It
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 52 Male 1/2/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Proteinuria Other Serious 40 Female 1/2/2013 Other Health Professional It
Primary
Secondary
Concomitant
Toxicity To Various Agents Other Serious 7 Male 1/3/2013 Other Health Professional Jp
Primary
Secondary
Toxicity To Various Agents Other Serious 6 Male 1/3/2013 Other Health Professional Jp
Primary
Secondary
Toxicity To Various Agents Other Serious 5 Female 1/3/2013 Other Health Professional Jp
Primary
Secondary
Spondylitis Other Serious 48 Male 1/10/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Death 47 Male 1/11/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Hepatocellular Injury Other Serious 7/18/2008 39 Female 1/30/2013 Other Health Professional Fr
Primary
Secondary
Death Death 7/17/1992 21 Male 172 lb 1/29/2013 Physician De
Primary
Concomitant
Urinary Tract Pain Hospitalization 10/4/2012 10 Male 73 lb 3/13/2013 Physician Jp
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 78 Male 2/19/2013 Other Health Professional Gr
Primary
Secondary
Concomitant
Pneumonia Death 6/26/2012 44 Male 2/28/2013 Other Health Professional Es
Primary
Secondary
Concomitant
Tracheitis Death 1/17/2011 45 Male 4/19/2013 Other Health Professional Es
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 7/1/2011 31 NotSpecified 2/22/2013 Other Health Professional It
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 1/11/2011 NotSpecified 2/22/2013 Other Health Professional It
Primary
Secondary
Concomitant
Pericarditis Other Serious 7/21/2011 58 Male 2/22/2013 Other Health Professional It
Primary
Secondary
Concomitant
Respiratory Failure Other Serious NotSpecified 2/24/2013 Other Health Professional No
Primary
Secondary
Concomitant
Post Transplant Lymphoproliferative Disorder Other Serious 2/20/2012 23 Female 84 lb 4/2/2013 Physician Jp
Primary
Concomitant
Pyrexia Hospitalization 7/28/2012 2 Male 24 lb 3/28/2013 Physician Jp
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 42 Male 5/8/2013 Physician Jp
Primary
Concomitant
Vomiting Death 44 Female 4/1/2013 Other Health Professional Ca
Primary
Secondary
Concomitant
Water Intoxication Other Serious 69 Male 4/4/2013 Other Health Professional Jp
Primary
Secondary
Hypertrichosis Other Serious 5 Male 4/1/2013 Other Health Professional Gb
Primary
Concomitant
Toxicity To Various Agents Other Serious 11 Male 4/9/2013 Other Health Professional Pl
Primary
Secondary
Herpes Zoster Other Serious 4/2010 36 Female 4/26/2013 Other Health Professional Jp
Primary
Concomitant
Graft Versus Host Disease Death 48 Female 5/2/2013 Other Health Professional Mx
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 66 Male 5/30/2013 Other Health Professional Jp
Primary
Secondary
Venoocclusive Disease Death 3 Male 5/30/2013 Other Health Professional Gb
Primary
Secondary
Surgical Procedure Repeated Other Serious 5 NotSpecified 5/30/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 52 Male 6/11/2013 Other Health Professional Fr
Primary
Secondary
Interstitial Lung Disease Death 2012 40 Male 6/11/2013 Pharmacist Jp
Primary
Concomitant
White Blood Cell Count Increased Death 55 Female 6/27/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Rash Generalised Other Serious 2 NotSpecified 6/20/2013 Other Health Professional Gb
Primary
Concomitant
Renal Impairment Other Serious 13 NotSpecified 6/21/2013 Other Health Professional Co
Primary
Secondary
Concomitant
Sepsis Other Serious 8 Female 6/28/2013 Other Health Professional Gb
Primary
Secondary
Toxicity To Various Agents Other Serious 5 Female 7/2/2013 Other Health Professional Jp
Primary
Secondary
Urinary Tract Infection Death 5/2002 48 Female 7/2/2013 Other Health Professional At
Primary
Secondary
Concomitant
Drug Ineffective Other Serious NotSpecified 7/10/2013 Other Health Professional De
Primary
Secondary
Concomitant
Acute Lymphocytic Leukaemia Recurrent Other Serious NotSpecified 7/10/2013 Other Health Professional De
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious NotSpecified 7/10/2013 Other Health Professional De
Primary
Secondary
Concomitant

Drug Data