Aprepitant



Indications and Reactions:

Role Indications Reactions
Primary
Prophylaxis Of Nausea And Vomiting 32.6%
Chemotherapy 16.3%
Breast Cancer 7.7%
Prophylaxis 6.3%
Pain 5.0%
Bone Sarcoma 4.1%
Nausea 3.6%
Analgesic Therapy 3.2%
Infection Prophylaxis 3.2%
Vomiting 3.2%
Antifungal Prophylaxis 2.3%
Lung Neoplasm Malignant 2.3%
Infection 1.8%
Breast Neoplasm 1.4%
Fluid Replacement 1.4%
Premedication 1.4%
Synovial Sarcoma 1.4%
Yolk Sac Tumour Site Unspecified 1.4%
Bladder Cancer 0.9%
Constipation Prophylaxis 0.9%
Electrocardiogram T Wave Inversion 14.7%
Febrile Neutropenia 8.8%
Hiccups 8.8%
Swollen Tongue 8.8%
Non-cardiac Chest Pain 5.9%
Pancreatitis 5.9%
Pyrexia 5.9%
Sepsis 5.9%
Anaphylactic Shock 2.9%
Atrial Fibrillation 2.9%
Cellulitis 2.9%
Clostridium Difficile Infection 2.9%
Drug Interaction 2.9%
Dyspnoea 2.9%
Flank Pain 2.9%
Haematuria 2.9%
Hyponatraemia 2.9%
Hypophagia 2.9%
Logorrhoea 2.9%
Nausea 2.9%
Secondary
Prophylaxis Of Nausea And Vomiting 36.7%
Chemotherapy 7.7%
Pain 6.0%
Analgesic Therapy 6.0%
Product Used For Unknown Indication 5.5%
Mucosal Inflammation 5.1%
Prophylaxis 5.0%
Infection 3.6%
Constipation 3.0%
Neoplasm Malignant 3.0%
Bone Sarcoma 2.5%
Antiemetic Supportive Care 2.5%
Nausea 2.3%
Anticoagulant Therapy 2.0%
Anaesthesia 1.9%
Device Related Infection 1.7%
Menstrual Disorder 1.7%
Haemoglobin Decreased 1.5%
Vomiting 1.2%
Fluid Replacement 1.1%
Vena Cava Thrombosis 38.2%
Off Label Use 6.9%
Febrile Neutropenia 6.0%
Sinus Arrhythmia 5.2%
Lung Cancer Metastatic 4.3%
Vomiting 4.3%
Electrocardiogram T Wave Inversion 3.9%
Rhinorrhoea 3.9%
Swollen Tongue 3.9%
Peritonitis 3.0%
Large Intestine Perforation 2.6%
Small Intestinal Haemorrhage 2.6%
Thrombocytopenia 2.6%
Haematuria 2.1%
Pain In Extremity 2.1%
Pyrexia 2.1%
Constipation 1.7%
Malaise 1.7%
Somnolence 1.7%
Abdominal Pain 1.3%
Concomitant
Drug Use For Unknown Indication 20.5%
Product Used For Unknown Indication 16.3%
Prophylaxis 10.8%
Breast Cancer 9.7%
Nausea 8.4%
Non-small Cell Lung Cancer 5.1%
Vomiting 3.6%
Pain 2.9%
Prophylaxis Of Nausea And Vomiting 2.8%
Premedication 2.6%
Sarcoma Metastatic 2.4%
Gastric Cancer 2.4%
Chemotherapy 2.1%
Hypertension 2.0%
Head And Neck Cancer 1.9%
Ovarian Cancer 1.5%
Constipation 1.4%
Diarrhoea 1.3%
Stomatitis 1.1%
B-cell Lymphoma 1.1%
Vomiting 17.2%
Febrile Neutropenia 8.1%
Thrombocytopenia 8.1%
Pyrexia 6.5%
Pulmonary Embolism 5.5%
Small Intestinal Obstruction 5.2%
Diarrhoea 4.9%
White Blood Cell Count Decreased 4.9%
Death 4.5%
Septic Shock 4.5%
Pleural Effusion 3.9%
Renal Failure 3.6%
Renal Failure Acute 3.6%
Hypomagnesaemia 3.2%
Oral Candidiasis 3.2%
Pneumonia 2.9%
Abdominal Pain 2.6%
Deafness Neurosensory 2.6%
Left Ventricular Dysfunction 2.6%
Mucosal Inflammation 2.6%
Interacting
Premedication 24.1%
Ovarian Cancer Stage Iii 16.9%
Prophylaxis Of Nausea And Vomiting 16.9%
Sarcoma Uterus 14.5%
Ovarian Neoplasm 7.2%
Anxiety 4.8%
Depression 4.8%
Ovarian Cancer Metastatic 4.8%
Bone Sarcoma 3.6%
Laryngeal Cancer Stage 0 2.4%
Mental Status Changes 31.3%
Vomiting 31.3%
Renal Impairment 25.0%
Encephalopathy 6.3%
Transaminases Increased 6.3%