Aprepitant combined with Cisplatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Teratoma Other Serious 8/28/2005 Female 1/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 2/19/2006 67 Male 146 lb 3/15/2006 Other Health Professional Argentina
Primary
Secondary
Concomitant
Anaphylactic Reaction Other Serious 3/28/2006 62 Female 3/30/2006 Physician Germany
Primary
Concomitant
Pyrexia Required Intervention 1/4/2006 56 Male 182 lb 2/14/2006 Pharmacist United States
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 3/28/2006 62 Female 4/13/2006 Physician Germany
Primary
Concomitant
Thrombocytopenia Other Serious 4/23/2006 33 Female 7/6/2006 Consumer Ireland
Primary
Secondary
Concomitant
Vomiting Other Serious 8/25/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/23/2006 33 Female 9/15/2006 Consumer Ireland
Primary
Secondary
Concomitant
Vomiting Required Intervention 7/24/2006 55 Male 179 lb 8/22/2006 Pharmacist United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 9/15/2006 46 Female 185 lb 11/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 9/15/2006 46 Female 185 lb 11/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 9/15/2006 46 Female 185 lb 11/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 10/3/2006 46 Female 185 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/19/2006 79 Female 119 lb 12/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 10/25/2006 72 Male 12/29/2006 Consumer United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 10/9/2006 Male 130 lb 1/4/2007 Other Health Professional France
Primary
Secondary
Concomitant
Neutropenia Other Serious 10/19/2006 79 Female 119 lb 1/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 10/19/2006 79 Female 119 lb 1/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/15/2007 62 Male 1/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 10/25/2006 72 Male 2/12/2007 Consumer Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 10/25/2006 72 Male 2/13/2007 Consumer Germany
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 12/30/2006 42 Male 2/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Peritonitis Hospitalization 1/23/2007 46 Male 3/13/2007 Switzerland
Primary
Secondary
Concomitant
Encephalopathy Other Serious 57 Female 4/13/2007 Other Health Professional France
Primary
Secondary
Interacting
Renal Failure Hospitalization 1/15/2007 62 Male 4/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 7/6/2007 Female 7/23/2007 Physician United States
Primary
Concomitant
Intestinal Perforation Hospitalization 7/29/2007 Female 8/7/2007 Physician United States
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 7/6/2007 Female 8/9/2007 Physician United States
Primary
Concomitant
Hyponatraemia Hospitalization 7/29/2007 Female 8/10/2007 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 7/29/2007 Female 8/31/2007 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/29/2007 Female 9/17/2007 Physician United States
Primary
Secondary
Concomitant
Stomach Mass Hospitalization 1/15/2007 62 Male 9/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 11/3/2007 Female 11/26/2007 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 11/3/2007 Female 11/28/2007 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 11/3/2007 Female 12/17/2007 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 1/15/2007 62 Male 12/26/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/15/2007 62 Male 1/4/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/1/2007 31 Male 1/31/2008 Other Health Professional Belgium
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 10/29/2007 Female 1/31/2008 Other Health Professional France
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 11/3/2007 Female 2/8/2008 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 2/8/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/29/2007 Female 2/8/2008 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 2/14/2008 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 2/29/2008 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 3/13/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/29/2007 Female 3/19/2008 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 11/3/2007 Female 3/20/2008 Physician United States
Primary
Concomitant
Paraesthesia Oral 10/4/2007 Female 3/28/2008 Other Health Professional United States
Primary
Concomitant
Urticaria 2/8/2007 70 Male 3/28/2008 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 1/15/2007 62 Male 4/15/2008 Physician United States
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/18/2008 Female 6/27/2008 Physician United States
Primary
Concomitant
Pain Hospitalization 6/8/2008 Male 7/28/2008 Physician Spain
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/1/2007 31 Male 7/31/2008 Other Health Professional Belgium
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 7/24/2008 Female 8/1/2008 Physician United States
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/18/2008 Female 8/8/2008 Consumer United States
Primary
Concomitant
Logorrhoea Hospitalization 5/13/2008 59 Male 8/15/2008 Other Health Professional France
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 7/24/2008 Female 9/17/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 4/7/2008 56 Male 150 lb 9/22/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 9/22/2008 59 Female 218 lb 10/3/2008 United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 9/22/2008 59 Female 218 lb 10/9/2008 United Kingdom
Primary
Secondary
Concomitant
Malaise Hospitalization 3/15/2007 78 Male 201 lb 10/9/2008 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Hospitalization 8/26/2008 51 Female 10/14/2008 Consumer India
Primary
Concomitant
Abdominal Distension Hospitalization 10/4/2008 45 Male 165 lb 10/17/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Abdominal Distension Hospitalization 10/4/2008 45 Male 165 lb 10/28/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 5/14/2008 61 Female 11/10/2008 Physician Switzerland
Primary
Secondary
Concomitant
Rash Macular Hospitalization 10/1/2008 69 Female 11/26/2008 Other Health Professional France
Primary
Secondary
Concomitant
Fibrin D Dimer Increased Hospitalization 4/23/2007 59 Female 12/12/2008 Consumer United States
Primary
Secondary
Concomitant
Phlebitis Hospitalization 12/4/2008 34 Female 12/11/2008 France
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 12/4/2008 34 Female 12/16/2008 France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/7/2008 67 Male 12/17/2008 Physician France
Primary
Secondary
Concomitant
Clostridium Difficile Colitis Hospitalization 9/12/2008 Male 12/30/2008 Physician France
Primary
Concomitant
Pulmonary Embolism Life Threatening 12/4/2008 34 Female 12/19/2008 France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/7/2008 67 Male 12/23/2008 France
Primary
Secondary
Concomitant
Chest Pain Hospitalization 12/16/2008 Female 1/14/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 10/19/2008 67 Male 1/14/2009 France
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 12/4/2008 34 Female 1/28/2009 France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/19/2008 67 Male 1/29/2009 Physician France
Primary
Secondary
Concomitant
Vomiting Other Serious Female 173 lb 2/19/2009 Pharmacist United Kingdom
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 12/10/2008 77 Male 2/16/2009 Physician Netherlands
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/19/2008 67 Male 2/9/2009 France
Primary
Secondary
Concomitant
Chest Pain Hospitalization 12/16/2008 Female 2/27/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/19/2008 67 Male 3/2/2009 France
Primary
Secondary
Concomitant
Vomiting Other Serious 62 Female 173 lb 3/25/2009 Other Health Professional United Kingdom
Primary
Concomitant
Subcutaneous Abscess Other Serious Male 3/27/2009 Physician India
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 12/4/2008 34 Female 3/25/2009 France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/9/2009 48 Male 174 lb 3/23/2009 Physician United States
Primary
Secondary
Concomitant
Subcutaneous Abscess Other Serious 2/10/2009 Male 4/3/2009 Physician India
Primary
Concomitant
Renal Failure Life Threatening 3/25/2009 65 Male 4/1/2009 France
Primary
Secondary
Concomitant
Renal Failure Life Threatening 3/25/2009 65 Male 4/6/2009 France
Primary
Secondary
Concomitant
Subcutaneous Abscess Other Serious 2/10/2009 Male 4/13/2009 Physician India
Primary
Concomitant
Anaphylactic Shock Other Serious 11/20/2008 56 Female 121 lb 4/27/2009 Physician United Kingdom
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 10/6/2008 Male 4/27/2009 Physician France
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 1/21/2008 Male 5/1/2009 Physician Canada
Primary
Concomitant
Jugular Vein Thrombosis Other Serious 6/5/2009 33 Male 185 lb 6/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 5/26/2009 66 Female 101 lb 6/15/2009 United States
Primary
Secondary
Concomitant
Jugular Vein Thrombosis Other Serious 6/5/2009 33 Male 185 lb 6/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Ileus Hospitalization 9/14/2008 76 Male 194 lb 6/30/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Ileus Hospitalization 9/14/2008 76 Male 194 lb 7/8/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypophagia Hospitalization 10/16/2008 70 Male 7/6/2009 Physician Germany
Primary
Secondary
Concomitant
Jugular Vein Thrombosis Other Serious 6/5/2009 33 Male 185 lb 7/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Haematochezia Hospitalization 7/15/2009 67 Male 117 lb 7/31/2009 Consumer Germany
Primary
Secondary
Concomitant
Neoplasm Progression Other Serious 69 Female 8/7/2009
Primary
Secondary
Concomitant
Haematochezia Hospitalization 7/15/2009 67 Male 117 lb 8/10/2009 Consumer Germany
Primary
Secondary
Concomitant
Somnolence Other Serious 5/28/2005 Female 8/17/2009 Consumer Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/11/2007 107 lb 8/19/2009 Physician Netherlands
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 69 Female 8/31/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Teratoma Death 5/28/2005 Female 8/26/2009 United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 8/21/2009 68 Male 163 lb 9/9/2009 Consumer Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 8/21/2009 68 Male 163 lb 9/15/2009 Consumer Germany
Primary
Secondary
Concomitant
Haematochezia Hospitalization 7/15/2009 67 Male 117 lb 9/30/2009 Consumer Germany
Primary
Secondary
Concomitant
Septic Shock Death 10/11/2009 70 Male 104 lb 10/21/2009 Consumer United States
Primary
Secondary
Concomitant
Septic Shock Death 10/11/2009 70 Male 104 lb 11/11/2009 Consumer United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 10/8/2009 56 Male 132 lb 11/27/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Diverticular Perforation Other Serious 10/8/2009 56 Male 132 lb 12/1/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Lung Infiltration Other Serious 10/8/2009 56 Male 132 lb 12/18/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Lung Infiltration Other Serious 10/8/2009 56 Male 132 lb 12/22/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Respiratory Tract Infection Life Threatening 8/21/2009 68 Male 163 lb 12/23/2009 Consumer Germany
Primary
Secondary
Concomitant
Diarrhoea Death 12/19/2009 Male 174 lb 12/23/2009 Physician India
Primary
Secondary
Concomitant
Dyspnoea Life Threatening 12/24/2009 62 Male 128 lb 12/31/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Diarrhoea Death 12/19/2009 65 Male 174 lb 12/31/2009 Other Health Professional India
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/28/2009 51 Male 12/30/2009 France
Primary
Secondary
Concomitant
Dyspnoea Life Threatening 12/24/2009 62 Male 128 lb 1/14/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 32 Female 1/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 12/24/2009 62 Male 128 lb 1/19/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Speech Disorder Developmental Hospitalization 32 Female 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 32 Female 1/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/26/2010 60 Male 199 lb 1/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/3/2008 Female 163 lb 2/2/2010 Physician France
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 32 Female 2/2/2010
Primary
Secondary
Concomitant
Death Death 12/23/2009 Male 168 lb 1/29/2010 Physician Spain
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 8/21/2009 68 Male 163 lb 2/9/2010 Consumer Germany
Primary
Secondary
Concomitant
Pneumonitis Life Threatening 12/24/2009 62 Male 128 lb 2/11/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Death Death 2/4/2010 52 Male 2/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Malaise Hospitalization 9/1/2009 Male 2/12/2010 Other Health Professional France
Primary
Secondary
Pneumonia Other Serious 10/8/2009 56 Male 132 lb 2/15/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/3/2009 47 Male 2/19/2010 Physician Portugal
Primary
Secondary
Concomitant
Malaise Hospitalization 9/1/2009 Male 2/18/2010 Other Health Professional France
Primary
Secondary
Thrombocytopenia Other Serious 12/24/2009 62 Male 128 lb 2/23/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Ileus Hospitalization 1/31/2010 Female 104 lb 2/23/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pneumonia Other Serious 10/8/2009 56 Male 132 lb 3/4/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Ileus Hospitalization 1/31/2010 66 Female 104 lb 3/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 8/21/2009 68 Male 163 lb 3/17/2010 Consumer Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/28/2009 66 Male 3/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/6/2009 65 Female 170 lb 3/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Diarrhoea Death 12/19/2009 Male 174 lb 3/16/2010 Physician India
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/6/2009 65 Female 170 lb 3/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Diarrhoea Death 12/19/2009 65 Male 174 lb 3/25/2010 Other Health Professional India
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/21/2009 Male 164 lb 3/25/2010 Physician Germany
Primary
Secondary
Concomitant
Ileus Hospitalization 1/31/2010 66 Female 104 lb 4/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data