Zoladex



Indications and Reactions:

Role Indications Reactions
Primary
Prostate Cancer 52.5%
Breast Cancer 13.6%
Hypertension 7.9%
Endometriosis 6.3%
Uterine Leiomyoma 2.1%
Pain 1.8%
Insomnia 1.8%
Benign Prostatic Hyperplasia 1.5%
Diabetes Mellitus 1.4%
Gastritis 1.3%
Gastritis Atrophic 1.3%
Asthma 1.2%
Depression 1.2%
Breast Cancer Female 1.1%
Conjunctivitis Allergic 1.0%
Constipation 1.0%
Hyperlipidaemia 0.9%
Lumbar Spinal Stenosis 0.9%
Cardiac Failure 0.7%
Hyperuricaemia 0.7%
Death 28.5%
Interstitial Lung Disease 15.6%
Weight Increased 11.4%
Prostatic Specific Antigen Increased 5.1%
Vomiting 4.4%
Hot Flush 3.4%
Prostate Cancer 3.4%
Myocardial Infarction 3.2%
Weight Decreased 3.2%
Hepatic Function Abnormal 2.1%
Malaise 2.1%
Malignant Neoplasm Progression 2.1%
Neoplasm Malignant 2.1%
Psychotic Disorder 2.1%
Cerebrovascular Accident 1.9%
Deep Vein Thrombosis 1.9%
Injection Site Haematoma 1.9%
Injection Site Haemorrhage 1.9%
Liver Function Test Abnormal 1.9%
White Blood Cell Count Decreased 1.9%
Secondary
Prostate Cancer 49.2%
Breast Cancer 17.2%
Product Used For Unknown Indication 5.7%
Hypertension 4.6%
Breast Cancer Metastatic 4.1%
Insomnia 2.5%
Diabetes Mellitus 2.5%
Her-2 Positive Breast Cancer 2.0%
Endometriosis 1.7%
Pain 1.6%
Uterine Leiomyoma 1.4%
Drug Use For Unknown Indication 1.1%
Vaginal Haemorrhage 0.9%
Benign Prostatic Hyperplasia 0.8%
Bone Disorder 0.8%
Anaemia 0.8%
Blood Cholesterol Increased 0.8%
Glaucoma 0.8%
Gastrooesophageal Reflux Disease 0.7%
Reflux Oesophagitis 0.7%
Weight Increased 13.0%
Vomiting 6.9%
Malignant Neoplasm Progression 6.5%
Cerebral Infarction 5.1%
Hypokalaemia 5.1%
Interstitial Lung Disease 5.1%
Pain 5.1%
White Blood Cell Disorder 5.1%
Liver Disorder 4.6%
Platelet Count Decreased 4.6%
Renal Impairment 4.6%
Diabetes Mellitus 4.2%
Neoplasm Progression 4.2%
Orthostatic Hypotension 4.2%
Surgery 4.2%
Hepatic Function Abnormal 3.7%
Pleural Effusion 3.7%
Thrombocytopenia 3.7%
Death 3.2%
Disease Progression 3.2%
Concomitant
Prostate Cancer 26.5%
Prostate Cancer Metastatic 10.6%
Breast Cancer 10.2%
Metastases To Bone 8.7%
Product Used For Unknown Indication 7.7%
Hypertension 6.6%
Pain 4.9%
Drug Use For Unknown Indication 4.5%
Prophylaxis 3.4%
Depression 2.7%
Hormone Therapy 2.4%
Breast Cancer Metastatic 2.0%
Nausea 1.6%
Diabetes Mellitus 1.5%
Bone Pain 1.2%
Constipation 1.2%
Osteoporosis 1.2%
Anaemia 1.1%
Drug Therapy 1.0%
General Physical Condition 1.0%
Vomiting 12.7%
Weight Decreased 12.7%
Tooth Extraction 9.4%
Osteonecrosis 5.3%
Pyrexia 5.3%
Death 4.9%
Prostatic Specific Antigen Increased 4.7%
White Blood Cell Count Decreased 4.7%
Swelling 4.5%
Toothache 4.0%
White Blood Cell Count Increased 4.0%
Pneumonia 3.6%
Prostate Cancer 3.6%
Osteonecrosis Of Jaw 3.3%
Pulmonary Embolism 3.3%
Dyspnoea 2.9%
Malaise 2.9%
Wound Infection Staphylococcal 2.9%
Cerebral Ischaemia 2.7%
Renal Failure Acute 2.7%
Interacting
Hormone Therapy 63.6%
Prostate Cancer 22.7%
Immunosuppressant Drug Therapy 13.6%
Drug Interaction 75.0%
Ventricular Extrasystoles 25.0%