Zelboraf



Indications and Reactions:

Role Indications Reactions
Primary
Product Used For Unknown Indication 35.5%
Malignant Melanoma 24.0%
Metastatic Malignant Melanoma 22.2%
Pain 4.0%
Hypertension 3.5%
Neoplasm Malignant 2.1%
Nausea 1.0%
Depression 0.9%
Prophylaxis 0.9%
Diabetes Mellitus 0.7%
Anxiety 0.7%
Constipation 0.6%
Insomnia 0.6%
Malignant Melanoma Stage Iv 0.6%
Hypothyroidism 0.6%
Metastases To Central Nervous System 0.5%
Atrial Fibrillation 0.4%
Convulsion 0.4%
Rash 0.4%
Skin Cancer 0.4%
Death 39.3%
Disease Progression 15.0%
Rash 6.9%
Fatigue 3.7%
Weight Decreased 3.7%
Vomiting 3.2%
Malignant Melanoma 3.0%
Arthralgia 2.6%
Metastases To Central Nervous System 2.6%
Metastatic Malignant Melanoma 2.2%
Neoplasm 2.2%
Sunburn 2.1%
Pyrexia 2.0%
Renal Failure 1.9%
Photosensitivity Reaction 1.7%
Renal Failure Acute 1.6%
Squamous Cell Carcinoma 1.6%
Dysphagia 1.6%
Nausea 1.6%
Skin Papilloma 1.6%
Secondary
Metastatic Malignant Melanoma 24.6%
Malignant Melanoma 20.4%
Prophylaxis 12.1%
Product Used For Unknown Indication 9.3%
Pain 4.9%
Essential Hypertension 4.4%
Hypertension 3.2%
Insomnia 2.8%
Diarrhoea 2.4%
Thyroid Cancer 2.3%
Thyroidectomy 2.2%
Breast Cancer Metastatic 1.9%
Hypothyroidism 1.8%
Depression 1.4%
Nausea 1.4%
Neoplasm Malignant 1.2%
Epilepsy 1.1%
Arthralgia 1.0%
Metastases To Central Nervous System 1.0%
Anticoagulant Therapy 0.8%
Weight Decreased 15.0%
Death 12.4%
Fatigue 8.6%
Rash 8.6%
Vomiting 5.6%
Blood Creatinine Increased 4.9%
Blood Uric Acid Increased 4.5%
Rash Generalised 4.1%
Nausea 3.8%
Sunburn 3.4%
Arthralgia 3.0%
Renal Failure 3.0%
Squamous Cell Carcinoma Of Skin 3.0%
Swelling Face 3.0%
Thrombocytopenia 3.0%
Tumour Lysis Syndrome 3.0%
Visual Impairment 3.0%
Diarrhoea 2.6%
Renal Failure Acute 2.6%
Skin Papilloma 2.6%
Concomitant
Epilepsy 19.4%
Metastatic Malignant Melanoma 16.1%
Malignant Melanoma 9.7%
Neoplasm Malignant 6.5%
Skin Cancer 6.5%
Back Pain 3.2%
Brain Oedema 3.2%
Convulsion 3.2%
Depression 3.2%
Metastasis 3.2%
Multiple Myeloma 3.2%
Myocardial Infarction 3.2%
Nausea 3.2%
Nuclear Magnetic Resonance Imaging Brain 3.2%
Osteoporosis 3.2%
Pain 3.2%
Polycythaemia Vera 3.2%
Product Used For Unknown Indication 3.2%
Weight Decreased 16.7%
Death 8.3%
Hot Flush 8.3%
Lethargy 8.3%
Livedo Reticularis 8.3%
Malignant Melanoma 8.3%
Off Label Use 8.3%
Partial Seizures 8.3%
Sudden Death 8.3%
Swelling 8.3%
Thrombocytopenia 8.3%
Interacting
Malignant Melanoma 33.3%
Metastatic Malignant Melanoma 16.7%
Nervous System Disorder 16.7%
Oral Candidiasis 16.7%
Convulsion 8.3%
Gastrooesophageal Reflux Disease 8.3%
Drug Interaction 33.3%
Neutropenia 33.3%
Skin Toxicity 16.7%
Squamous Cell Carcinoma 16.7%