Vemurafenib



Indications and Reactions:

Role Indications Reactions
Primary
Metastatic Malignant Melanoma 37.8%
Malignant Melanoma 27.6%
Product Used For Unknown Indication 13.7%
Prophylaxis 4.3%
Hypertension 3.1%
Pain 2.0%
Thyroid Cancer 1.5%
Nausea 1.1%
Arthralgia 1.0%
Hypothyroidism 1.0%
Neoplasm Malignant 1.0%
Back Pain 0.9%
Constipation 0.8%
Essential Hypertension 0.8%
Headache 0.7%
Neoplasm 0.7%
Diarrhoea 0.6%
Insomnia 0.6%
Depression 0.6%
Diabetes Mellitus 0.5%
Disease Progression 19.9%
Anaemia 7.8%
Death 7.1%
Squamous Cell Carcinoma Of Skin 5.6%
Rash 5.4%
Squamous Cell Carcinoma 4.8%
Weight Decreased 4.7%
Malignant Melanoma 4.3%
Pyrexia 4.1%
Dermatitis Exfoliative 3.9%
Dyspnoea 3.7%
Epilepsy 3.5%
Renal Failure Acute 3.5%
General Physical Health Deterioration 3.4%
Pericarditis 3.4%
Dehydration 3.0%
Fatigue 3.0%
Melanocytic Naevus 3.0%
Pancreatitis 3.0%
Pulmonary Embolism 3.0%
Secondary
Prophylaxis 23.9%
Metastatic Malignant Melanoma 20.3%
Malignant Melanoma 19.0%
Essential Hypertension 8.5%
Insomnia 4.7%
Diarrhoea 4.5%
Thyroid Cancer 4.5%
Thyroidectomy 2.7%
Hypertension 2.6%
Product Used For Unknown Indication 2.5%
Nausea 0.9%
Hypercholesterolaemia 0.8%
Metastases To Central Nervous System 0.7%
Pain 0.7%
Abdominal Pain Lower 0.6%
Coronary Artery Disease 0.6%
Headache 0.6%
Hypothyroidism 0.6%
Neoplasm Malignant 0.5%
Papillary Thyroid Cancer 0.5%
Rash Erythematous 11.2%
Hypotension 7.4%
Rash 7.4%
Squamous Cell Carcinoma Of Skin 7.2%
Rash Macular 6.9%
Anaemia 5.2%
Dermatitis Exfoliative 5.2%
Alanine Aminotransferase Increased 4.9%
Blood Creatinine Increased 4.6%
Malignant Melanoma 4.3%
Pyrexia 4.3%
Renal Failure 4.0%
Weight Decreased 4.0%
Pancreatitis 3.7%
Squamous Cell Carcinoma 3.7%
Headache 3.4%
Cellulitis 3.2%
Dehydration 3.2%
Epilepsy 3.2%
Hepatotoxicity 3.2%
Concomitant
Product Used For Unknown Indication 42.9%
Malignant Melanoma 21.4%
Metastatic Malignant Melanoma 21.4%
Deep Vein Thrombosis 7.1%
Neoplasm 7.1%
Adverse Drug Reaction 10.0%
Death 10.0%
Malignant Melanoma 10.0%
Metastatic Malignant Melanoma 10.0%
Rash Generalised 10.0%
Renal Failure 10.0%
Respiratory Disorder 10.0%
Sinus Disorder 10.0%
Spinal Cord Compression 10.0%
Thrombocytopenia 10.0%
Interacting
Product Used For Unknown Indication 61.1%
Malignant Melanoma 15.6%
Metastatic Malignant Melanoma 14.4%
Oral Candidiasis 5.6%
Pain 2.2%
Nervous System Disorder 1.1%
Overdose 21.7%
Cholestasis 13.0%
Drug Interaction 13.0%
Pyrexia 13.0%
Alanine Aminotransferase Increased 8.7%
Fall 8.7%
Neutropenia 8.7%
Blood Alkaline Phosphatase Increased 4.3%
Chronic Obstructive Pulmonary Disease 4.3%
Condition Aggravated 4.3%