Valproate



Indications and Reactions:

Role Indications Reactions
Primary
Convulsion 21.7%
Product Used For Unknown Indication 19.6%
Epilepsy 18.5%
Complex Partial Seizures 5.4%
Partial Seizures 5.4%
Bipolar Disorder 3.3%
Drug Therapy 3.3%
Schizoaffective Disorder 3.3%
Schizophrenia 3.3%
Acute Hepatic Failure 2.2%
Brucellosis 2.2%
Grand Mal Convulsion 2.2%
Petit Mal Epilepsy 2.2%
Febrile Convulsion 1.1%
Affect Lability 1.1%
Chorea 1.1%
Cluster Headache 1.1%
Convulsion Prophylaxis 1.1%
Depression 1.1%
Febrile Seizure 1.1%
Toxic Epidermal Necrolysis 13.5%
Malnutrition 8.1%
Renal Tubular Disorder 8.1%
Toxicity To Various Agents 8.1%
Maternal Drugs Affecting Foetus 5.4%
Meningomyelocele 5.4%
Pancreatitis Acute 5.4%
Parkinsonism 5.4%
Sexually Inappropriate Behaviour 5.4%
Tachycardia 5.4%
Xanthoma 5.4%
Alopecia 2.7%
Drug Level Decreased 2.7%
Drug Reaction With Eosinophilia And Systemic Symptoms 2.7%
Ear Disorder 2.7%
Encephalopathy 2.7%
Epilepsy 2.7%
Heart Rate Increased 2.7%
Hyperammonaemic Encephalopathy 2.7%
Intentional Overdose 2.7%
Secondary
Product Used For Unknown Indication 19.0%
Epilepsy 16.2%
Convulsion 14.6%
Status Epilepticus 9.5%
Myoclonic Epilepsy 7.5%
Bipolar Disorder 6.3%
Hypertension 4.7%
Hiv Infection 4.3%
Infantile Spasms 2.4%
Autism 2.0%
Maternal Exposure Timing Unspecified 2.0%
Convulsion Prophylaxis 1.6%
Depression 1.6%
Foetal Exposure During Pregnancy 1.6%
Bipolar Ii Disorder 1.2%
Cerebellar Infarction 1.2%
Dementia Alzheimer's Type 1.2%
Metastatic Renal Cell Carcinoma 1.2%
Pneumonia Aspiration 1.2%
Migraine Prophylaxis 0.8%
Hypoglycaemia 15.9%
Grand Mal Convulsion 9.1%
Hypotonia 9.1%
Drug Ineffective 6.8%
Respiratory Disorder Neonatal 6.8%
Speech Disorder 6.8%
Drug Ineffective For Unapproved Indication 4.5%
Hyperammonaemic Encephalopathy 4.5%
Hyponatraemia 4.5%
Slow Response To Stimuli 4.5%
Toxic Epidermal Necrolysis 4.5%
Vomiting 4.5%
Accidental Exposure To Product 2.3%
Acquired Haemophilia 2.3%
Atrial Septal Defect 2.3%
Convulsion 2.3%
Cryptorchism 2.3%
Delirium 2.3%
Disorientation 2.3%
Drug Exposure During Pregnancy 2.3%
Concomitant
Epilepsy 39.8%
Product Used For Unknown Indication 24.2%
Bipolar Disorder 6.6%
Convulsion 6.6%
Status Epilepticus 3.5%
Schizophrenia 3.2%
Depression 2.4%
Partial Seizures 2.2%
Bipolar Ii Disorder 1.7%
Acute Myeloid Leukaemia 1.5%
Hypertension 1.3%
Atrial Fibrillation 1.0%
Breast Cancer 1.0%
Nasopharyngitis 0.8%
Relapsing-remitting Multiple Sclerosis 0.8%
Agitated Depression 0.7%
Anxiety 0.7%
Diabetes Mellitus 0.7%
Hiv Infection 0.7%
Hypothyroidism 0.7%
Status Epilepticus 10.0%
Confusional State 7.8%
Weight Decreased 6.7%
Drug Ineffective 5.6%
Epilepsy 5.6%
Grand Mal Convulsion 5.6%
Somnambulism 5.6%
Tachycardia 5.6%
Toxicity To Various Agents 5.6%
Tremor 5.6%
Convulsion 4.4%
Rhabdomyolysis 4.4%
Sepsis 4.4%
White Blood Cell Count Decreased 4.4%
Mania 3.3%
Overdose 3.3%
Restless Legs Syndrome 3.3%
Suicide Attempt 3.3%
Vomiting 3.3%
Drug Ineffective For Unapproved Indication 2.2%
Interacting
Bipolar I Disorder 30.4%
Hypertension 17.4%
Anaesthesia 8.7%
Epilepsy 8.7%
Hormone Replacement Therapy 8.7%
Neuralgia 8.7%
Schizoaffective Disorder 8.7%
Diabetes Mellitus 4.3%
Hyperlipidaemia 4.3%
Drug Interaction 40.0%
Hyperammonaemic Encephalopathy 20.0%
Overdose 20.0%
Respiratory Alkalosis 20.0%