Trabectedin



Indications and Reactions:

Role Indications Reactions
Primary
Ovarian Cancer 28.1%
Product Used For Unknown Indication 15.7%
Ovarian Cancer Recurrent 11.9%
Premedication 6.5%
Hypertension 5.4%
Cardiovascular Disorder 4.3%
Sarcoma 4.3%
Pain In Extremity 3.2%
Depression 2.7%
Drug Use For Unknown Indication 2.2%
Anxiety 1.6%
Blood Calcium Decreased 1.6%
Cardiac Failure Chronic 1.6%
Chemotherapy 1.6%
Diabetes Mellitus 1.6%
Hypercholesterolaemia 1.6%
Hypothyroidism 1.6%
Oedema Due To Cardiac Disease 1.6%
Platelet Aggregation Inhibition 1.6%
Liposarcoma 1.1%
Bone Marrow Failure 13.3%
Vomiting 13.3%
Renal Failure Acute 11.1%
Thrombocytopenia 8.9%
Atrial Fibrillation 6.7%
Rhabdomyolysis 6.7%
Cardiac Failure 4.4%
Haematotoxicity 4.4%
Hepatic Function Abnormal 4.4%
Urinary Retention 4.4%
Blood Creatine Increased 2.2%
Blood Creatinine Increased 2.2%
Cognitive Disorder 2.2%
Colitis 2.2%
Diarrhoea 2.2%
Drug Interaction 2.2%
Dyspnoea 2.2%
Extravasation 2.2%
Febrile Neutropenia 2.2%
Hepatic Enzyme Increased 2.2%
Secondary
Hypertension 9.4%
Ovarian Cancer 8.8%
Premedication 8.3%
Product Used For Unknown Indication 8.0%
Ovarian Cancer Recurrent 7.1%
Vomiting 6.8%
Nausea 5.8%
Dyspepsia 5.6%
Sarcoma 5.3%
Arthralgia 4.6%
Ovarian Neoplasm 4.1%
Prophylactic Chemotherapy 4.1%
Chemotherapy 3.6%
Liposarcoma 3.2%
Osteoporosis 3.1%
Diabetes Mellitus 2.6%
Pain 2.6%
Atrial Fibrillation 2.4%
Drug Use For Unknown Indication 2.4%
Pain In Extremity 2.4%
Sepsis 13.8%
Myalgia 11.9%
Bone Marrow Failure 8.3%
Cardiac Failure 7.3%
Cytolytic Hepatitis 7.3%
Upper Gastrointestinal Haemorrhage 4.6%
Vomiting 4.6%
Confusional State 3.7%
Idiopathic Thrombocytopenic Purpura 3.7%
Pericarditis 3.7%
Renal Failure Acute 3.7%
Thrombocytopenia 3.7%
Urinary Retention 3.7%
Ventricular Hypokinesia 3.7%
Blood Creatine Phosphokinase Increased 2.8%
Death 2.8%
Gamma-glutamyltransferase Increased 2.8%
Hyperkalaemia 2.8%
Hypotension 2.8%
Neutropenia 2.8%
Concomitant
Sarcoma 20.5%
Condition Aggravated 15.4%
Liposarcoma 15.4%
Product Used For Unknown Indication 10.3%
Prophylaxis 10.3%
Hypertension 7.7%
Deep Vein Thrombosis 5.1%
Metastases To Bone 5.1%
Depression 2.6%
Neoplasm Malignant 2.6%
Thrombosis 2.6%
Uterine Leiomyosarcoma 2.6%
Cardiac Failure 23.1%
Vomiting 23.1%
Off Label Use 15.4%
Urinary Tract Infection 15.4%
Aphasia 7.7%
Disease Progression 7.7%
Hypertensive Crisis 7.7%
Interacting
Product Used For Unknown Indication 28.0%
Cardiovascular Disorder 15.5%
Hiv Test Positive 13.0%
Drug Use For Unknown Indication 8.7%
Chemotherapy 6.8%
Hiv Infection 5.8%
Hypertension 5.8%
Sarcoma Metastatic 4.8%
Liposarcoma 3.9%
Premedication 1.9%
Sarcoma Uterus 1.9%
Metastases To Lung 1.4%
Uterine Leiomyosarcoma 1.4%
Ill-defined Disorder 1.0%
Pyrexia 24.0%
Drug Interaction 16.0%
Myalgia 16.0%
Ascites 8.0%
Lymphangiosis Carcinomatosa 8.0%
Chest Pain 4.0%
Cough 4.0%
General Physical Health Deterioration 4.0%
Hepatic Enzyme Increased 4.0%
Liver Function Test Abnormal 4.0%
Pancytopenia 4.0%
Rhabdomyolysis 4.0%