| Primary |
| Migraine |
50.5% |
| Drug Use For Unknown Indication |
26.9% |
| Product Used For Unknown Indication |
7.2% |
| Headache |
3.8% |
| Cluster Headache |
2.6% |
| Depression |
1.2% |
| Antiplatelet Therapy |
0.9% |
| Hypertension |
0.8% |
| Migraine Prophylaxis |
0.8% |
| Anxiety |
0.8% |
| Musculoskeletal Pain |
0.7% |
| Asthma |
0.6% |
| Pain |
0.5% |
| Hypercoagulation |
0.5% |
| Insomnia |
0.5% |
| Contraception |
0.4% |
| Migraine With Aura |
0.4% |
| Analgesia |
0.3% |
| Nausea |
0.3% |
| Trigeminal Neuralgia |
0.3% |
|
| Product Quality Issue |
45.4% |
| Drug Ineffective |
18.1% |
| Product Substitution Issue |
6.5% |
| Migraine |
4.3% |
| Vomiting |
3.8% |
| Therapeutic Response Decreased |
3.3% |
| Headache |
2.3% |
| Nausea |
1.8% |
| Urticaria |
1.8% |
| Therapeutic Response Unexpected With Drug Substitution |
1.7% |
| Drug Interaction |
1.3% |
| Somnolence |
1.3% |
| Drug Administration Error |
1.2% |
| Paraesthesia |
1.2% |
| Serotonin Syndrome |
1.2% |
| Overdose |
1.0% |
| Therapeutic Response Delayed |
1.0% |
| Thrombocytopenia |
1.0% |
| Drug Effect Decreased |
0.8% |
| Drug Exposure During Pregnancy |
0.8% |
|
| Secondary |
| Migraine |
42.2% |
| Product Used For Unknown Indication |
28.0% |
| Foetal Exposure During Pregnancy |
8.3% |
| Headache |
3.8% |
| Drug Use For Unknown Indication |
3.7% |
| Drug Exposure In Utero |
2.1% |
| Tubulointerstitial Nephritis |
1.8% |
| Musculoskeletal Pain |
1.5% |
| Pain |
1.3% |
| Crohn's Disease |
0.9% |
| Hypertension |
0.9% |
| Attention Deficit/hyperactivity Disorder |
0.7% |
| Cluster Headache |
0.7% |
| Depression |
0.7% |
| Panic Disorder |
0.7% |
| Blood Pressure Increased |
0.6% |
| Chronic Headaches |
0.6% |
| Prophylaxis |
0.6% |
| Anxiety |
0.4% |
| Chronic Paroxysmal Hemicrania |
0.4% |
|
| Drug Ineffective |
19.2% |
| Product Quality Issue |
14.4% |
| Vomiting |
10.4% |
| Headache |
7.2% |
| Migraine |
6.4% |
| Drug Hypersensitivity |
5.6% |
| Product Substitution Issue |
4.8% |
| Completed Suicide |
3.2% |
| Drug Abuse |
3.2% |
| Pain In Extremity |
3.2% |
| Paraesthesia |
3.2% |
| Arthralgia |
2.4% |
| Blood Pressure Increased |
2.4% |
| Injection Site Pain |
2.4% |
| Somnolence |
2.4% |
| Therapeutic Response Decreased |
2.4% |
| Ventricular Tachyarrhythmia |
2.4% |
| Aspiration |
1.6% |
| Cleft Palate |
1.6% |
| Malaise |
1.6% |
|
| Concomitant |
| Drug Use For Unknown Indication |
18.9% |
| Product Used For Unknown Indication |
18.8% |
| Migraine |
16.9% |
| Headache |
7.5% |
| Pain |
6.7% |
| Depression |
4.6% |
| Rheumatoid Arthritis |
3.6% |
| Contraception |
2.6% |
| Hypertension |
2.2% |
| Insomnia |
2.1% |
| Asthma |
2.0% |
| Gastrooesophageal Reflux Disease |
2.0% |
| Hypersensitivity |
1.8% |
| Multiple Sclerosis |
1.7% |
| Nausea |
1.7% |
| Hiv Infection |
1.4% |
| Sleep Disorder |
1.4% |
| Anxiety |
1.3% |
| Hepatitis C |
1.3% |
| Crohn's Disease |
1.3% |
|
| Vomiting |
11.7% |
| Tremor |
10.6% |
| Headache |
8.0% |
| Pulmonary Embolism |
6.4% |
| Weight Increased |
5.9% |
| Deep Vein Thrombosis |
4.8% |
| Fatigue |
4.8% |
| Pyrexia |
4.8% |
| Weight Decreased |
4.8% |
| Myoclonus |
4.3% |
| Nausea |
4.3% |
| Dysgeusia |
3.7% |
| Torsade De Pointes |
3.7% |
| Anal Cancer |
3.2% |
| Anxiety |
3.2% |
| Hypertension |
3.2% |
| Incorrect Dose Administered |
3.2% |
| Migraine |
3.2% |
| Rhabdomyolysis |
3.2% |
| Throat Tightness |
3.2% |
|
| Interacting |
| Migraine |
20.5% |
| Depression |
17.9% |
| Analgesia |
15.4% |
| Drug Use For Unknown Indication |
15.4% |
| Product Used For Unknown Indication |
15.4% |
| Major Depression |
5.1% |
| Pain |
5.1% |
| Anxiety |
2.6% |
| Fibromyalgia |
2.6% |
|
| Serotonin Syndrome |
60.0% |
| Overdose |
13.3% |
| Appendicitis |
6.7% |
| Eye Movement Disorder |
6.7% |
| Oral Discomfort |
6.7% |
| Tenderness |
6.7% |
|