Rasburicase



Indications and Reactions:

Role Indications Reactions
Primary
Chemotherapy 20.9%
Hyperuricaemia 12.8%
Osteoporosis 10.5%
Acute Myeloid Leukaemia 7.0%
Back Pain 5.8%
Prophylactic 5.8%
Prophylaxis 5.8%
B-cell Lymphoma Stage Iv 4.7%
Lymphoma 4.7%
Tumour Lysis Syndrome 4.7%
Blood Uric Acid Increased 2.3%
Disseminated Intravascular Coagulation 2.3%
Multiple Myeloma 2.3%
Sedation 2.3%
Tumor Lysis Syndrome 2.3%
Acute Leukaemia 1.2%
Acute Lymphoblastic Leukemia 1.2%
Acute Lymphocytic Leukaemia 1.2%
Blood Pressure Decreased 1.2%
Blood Uric Acid 1.2%
Antibody Test Abnormal 11.4%
Death 11.4%
Hepatic Function Abnormal 8.6%
Methaemoglobinaemia 8.6%
Cardiac Arrest 5.7%
Disease Progression 5.7%
Dyspnoea 5.7%
Haemolytic Anaemia 5.7%
White Blood Cell Count Decreased 5.7%
Cerebral Haemorrhage 2.9%
Dialysis 2.9%
General Physical Health Deterioration 2.9%
Hepatotoxicity 2.9%
Hypoxia 2.9%
Leukopenia 2.9%
Neutrophil Count Increased 2.9%
Pancreatitis Acute 2.9%
Pulmonary Alveolar Haemorrhage 2.9%
Pyrexia 2.9%
Refusal Of Treatment By Patient 2.9%
Secondary
Product Used For Unknown Indication 20.2%
Drug Use For Unknown Indication 10.5%
Mantle Cell Lymphoma 9.7%
Acute Myeloid Leukaemia 7.5%
Burkitt's Lymphoma 6.7%
Leukaemic Infiltration Brain 6.7%
Premedication 4.1%
Bone Pain 3.7%
Chemotherapy 3.7%
Prophylaxis 3.4%
Leiomyosarcoma 3.0%
Prevention 3.0%
Acute Leukaemia 2.6%
Back Pain 2.2%
Gestational Trophoblastic Tumour 2.2%
Hyperuricaemia 2.2%
Leukaemia Recurrent 2.2%
Tumour Lysis Syndrome 2.2%
Acute Lymphocytic Leukaemia 1.9%
Chronic Lymphocytic Leukaemia 1.9%
Tumour Lysis Syndrome 16.1%
Pancreatitis Acute 9.7%
Cardiac Arrest 6.5%
Death 6.5%
Haemolytic Anaemia 6.5%
Renal Failure Acute 6.5%
Respiratory Failure 6.5%
Convulsion 3.2%
Dyskinesia 3.2%
Gastrointestinal Necrosis 3.2%
Haemoglobin Decreased 3.2%
Hepatic Function Abnormal 3.2%
Hypertriglyceridaemia 3.2%
Jaundice 3.2%
Neutrophil Count Increased 3.2%
Oxygen Saturation Decreased 3.2%
Pancreatitis 3.2%
Paroxysmal Arrhythmia 3.2%
Pneumonia 3.2%
Pseudomonas Infection 3.2%
Concomitant
Prophylaxis 17.5%
Product Used For Unknown Indication 17.0%
Acute Myeloid Leukaemia 13.2%
Acute Lymphocytic Leukaemia 7.9%
Drug Use For Unknown Indication 7.2%
Diffuse Large B-cell Lymphoma 6.3%
Nausea 3.5%
Pyrexia 3.4%
Premedication 3.3%
Hypertension 3.1%
Supplementation Therapy 2.5%
Acute Lymphocytic Leukaemia Recurrent 2.1%
Infection Prophylaxis 2.0%
Pain 2.0%
B-cell Lymphoma 1.6%
Constipation 1.5%
Febrile Neutropenia 1.5%
Chemotherapy 1.4%
Myelodysplastic Syndrome 1.4%
Sedation 1.4%
Septic Shock 18.6%
Tumour Lysis Syndrome 17.6%
Sepsis 6.9%
Renal Failure 5.9%
Death 4.9%
Epistaxis 4.9%
Hepatitis B 4.9%
Vomiting 4.9%
Pancreatitis Acute 3.9%
Thrombocytopenia 3.9%
Anaemia 2.9%
Nausea 2.9%
Pneumonia 2.9%
Skin Exfoliation 2.9%
C-reactive Protein Increased 2.0%
Cholecystitis Acute 2.0%
Diarrhoea 2.0%
Gastrointestinal Necrosis 2.0%
Hemiplegia 2.0%
Hepatic Failure 2.0%