Protamine



Combined with:

Indications and Reactions:

Role Indications Reactions
Primary
Heparin Neutralisation Therapy 42.9%
Anticoagulant Therapy 14.3%
Heart Valve Replacement 14.3%
Open Heart Surgery 14.3%
Toxicity To Various Agents 14.3%
Product Quality Issue 20.0%
Cerebral Disorder 10.0%
Hypotension 10.0%
Oxygen Saturation Decreased 10.0%
Right Ventricular Failure 10.0%
Swelling 10.0%
Thrombosis In Device 10.0%
Unresponsive To Stimuli 10.0%
Urticaria 10.0%
Secondary
Prosthesis Implantation 18.4%
Product Used For Unknown Indication 17.2%
Anticoagulant Therapy 9.2%
Antiplatelet Therapy 9.2%
Maintenance Of Anaesthesia 9.2%
Induction Of Anaesthesia 6.9%
Aortic Surgery 5.7%
Surgery 4.6%
Circulatory Collapse 3.4%
Heparin Neutralisation Therapy 3.4%
Blood Pressure Abnormal 2.3%
Haemorrhagic Disorder 2.3%
Anaesthesia 1.1%
Antibiotic Prophylaxis 1.1%
Aortic Valve Replacement 1.1%
Atrial Fibrillation 1.1%
Open Heart Surgery 1.1%
Prophylaxis 1.1%
Unevaluable Event 1.1%
Systemic Inflammatory Response Syndrome 23.1%
Muscular Weakness 15.4%
Hypoxia 7.7%
Intestinal Ischaemia 7.7%
Pain 7.7%
Product Quality Issue 7.7%
Transaminases Increased 7.7%
Type I Hypersensitivity 7.7%
Urticaria 7.7%
Urticaria Generalised 7.7%
Concomitant
Product Used For Unknown Indication 46.7%
Coronary Artery Bypass 19.3%
Aortic Valve Replacement 6.1%
Catheterisation Cardiac 4.0%
Mitral Valve Replacement 3.9%
Prophylaxis 3.0%
Surgery 2.5%
Mitral Valve Repair 2.1%
Hypertension 1.8%
Malignant Melanoma Stage Iii 1.3%
Coronary Artery Bypass Graft 1.2%
Cox-maze Procedure 1.2%
Tricuspid Valve Repair 1.2%
Gastric Cancer 1.0%
Anticoagulant Therapy 0.9%
Diabetes Mellitus 0.9%
Acute Coronary Syndrome 0.8%
Cardiac Operation 0.8%
Sternotomy 0.8%
Aortic Dissection 0.7%
Pain 14.2%
Unevaluable Event 12.0%
Fear 9.0%
Injury 8.6%
Anhedonia 7.3%
Stress 6.9%
Renal Failure 6.0%
Anxiety 5.6%
Renal Injury 5.6%
Emotional Distress 4.3%
Renal Failure Acute 4.3%
Renal Impairment 3.0%
Death 2.1%
Depression 2.1%
Renal Tubular Necrosis 2.1%
Cerebrovascular Accident 1.7%
Renal Failure Chronic 1.7%
Cellulitis 1.3%
Respiratory Failure 1.3%
Mental Disorder 0.9%