Orfadin



Indications and Reactions:

Role Indications Reactions
Primary
Tyrosinaemia 93.8%
Amino Acid Metabolism Disorder 1.5%
Alkaptonuria 1.0%
Anaemia 1.0%
Off Label Use 1.0%
Phenylketonuria 0.5%
Tyrosinemia Type I 0.5%
Vomiting 0.5%
Liver Transplant 31.0%
Treatment Noncompliance 12.7%
Death 9.5%
Hepatic Neoplasm Malignant 7.9%
Sepsis 4.0%
Amino Acid Level Increased 3.2%
Hepatic Failure 3.2%
Thrombocytopenia 3.2%
Vomiting 3.2%
Epilepsy 2.4%
General Physical Health Deterioration 2.4%
Hepatic Neoplasm 2.4%
Learning Disorder 2.4%
No Therapeutic Response 2.4%
Prothrombin Time Prolonged 2.4%
Brain Oedema 1.6%
Cognitive Disorder 1.6%
Haemorrhage 1.6%
Hepatic Cirrhosis 1.6%
Hepatomegaly 1.6%
Concomitant
Tyrosinaemia 100.0%
Vomiting 100.0%