L-Asparaginase



Indications and Reactions:

Role Indications Reactions
Primary
Acute Lymphocytic Leukaemia 39.1%
Prophylaxis 21.7%
Neoplasm Malignant 17.4%
Drug Use For Unknown Indication 13.0%
Infection Prophylaxis 8.7%
Hepatic Steatosis 11.8%
Staphylococcal Infection 11.8%
White Blood Cell Count Decreased 11.8%
Arthralgia 5.9%
Blood Glucose Increased 5.9%
Depression 5.9%
Dizziness 5.9%
Liver Injury 5.9%
Loss Of Consciousness 5.9%
Pyrexia 5.9%
Syncope 5.9%
Thrombosis 5.9%
Urticaria 5.9%
Ventricular Dysfunction 5.9%
Secondary
Acute Lymphocytic Leukaemia 62.3%
B Precursor Type Acute Leukaemia 6.2%
Extranodal Nk/t-cell Lymphoma, Nasal Type 5.1%
T-cell Lymphoma 3.8%
Non-hodgkin's Lymphoma 2.8%
T-cell Type Acute Leukaemia 2.1%
Prophylaxis 2.0%
Central Nervous System Lymphoma 1.9%
Leukaemia 1.5%
Prophylaxis Against Graft Versus Host Disease 1.4%
Acute Lymphoblastic Leukemia 1.3%
Chemotherapy 1.3%
Fungal Infection 1.2%
Malignant Histiocytosis 1.2%
Product Used For Unknown Indication 1.2%
Infection Prophylaxis 1.0%
Lymphocytic Leukaemia 1.0%
Acute Undifferentiated Leukaemia 0.9%
Bone Marrow Conditioning Regimen 0.9%
Lymphoblastic Lymphoma 0.9%
Sepsis 11.1%
Posterior Reversible Encephalopathy Syndrome 8.9%
Vomiting 8.9%
Thrombocytopenia 7.8%
White Blood Cell Count Decreased 7.8%
Septic Shock 6.7%
Staphylococcal Infection 6.7%
Stomatitis 4.4%
Unresponsive To Stimuli 4.4%
Death 3.3%
Mucosal Inflammation 3.3%
Multi-organ Failure 3.3%
Off Label Use 3.3%
Pulmonary Embolism 3.3%
Superior Sagittal Sinus Thrombosis 3.3%
Tonic Clonic Movements 3.3%
Venoocclusive Liver Disease 3.3%
Asthenia 2.2%
Chronic Myeloid Leukaemia 2.2%
Hypertriglyceridaemia 2.2%
Concomitant
Acute Lymphocytic Leukaemia 53.2%
Antibiotic Prophylaxis 8.6%
Drug Toxicity Prophylaxis 8.6%
Product Used For Unknown Indication 6.6%
Chemotherapy 4.4%
Prophylaxis 4.2%
Acute Lymphocytic Leukaemia Recurrent 2.2%
B Precursor Type Acute Leukaemia 1.9%
Febrile Neutropenia 1.7%
Prophylaxis Against Graft Versus Host Disease 1.7%
T-cell Type Acute Leukaemia 1.7%
Infection 1.1%
Graft Versus Host Disease 0.8%
Blood Triglycerides Increased 0.6%
Gastritis 0.6%
Insulin Resistance 0.6%
Menorrhagia 0.6%
Supplementation Therapy 0.6%
Abdominal Pain Upper 0.3%
Adverse Event 0.3%
Sepsis 56.9%
Haemolytic Anaemia 3.9%
No Therapeutic Response 3.9%
Off Label Use 3.9%
Cholestasis 2.0%
Convulsion 2.0%
Grand Mal Convulsion 2.0%
Hepatic Steatosis 2.0%
Hy's Law Case 2.0%
Ileus Paralytic 2.0%
Klebsiella Infection 2.0%
Neurological Symptom 2.0%
Neurotoxicity 2.0%
Pain In Jaw 2.0%
Paralysis Flaccid 2.0%
Pleural Effusion 2.0%
Pseudomonas Test Positive 2.0%
Pyrexia 2.0%
Renal Failure 2.0%
Renal Failure Acute 2.0%