Imatinib Mesylate



Indications and Reactions:

Role Indications Reactions
Primary
Chronic Myeloid Leukaemia 48.3%
Acute Lymphocytic Leukaemia 16.4%
Gastrointestinal Stromal Tumour 13.1%
Pulmonary Arterial Hypertension 4.3%
Prophylaxis 3.8%
Hypertension 3.0%
Glioblastoma Multiforme 2.0%
Acute Myeloid Leukaemia 1.0%
Angina Pectoris 1.0%
Interstitial Lung Disease 0.8%
Scleroderma 0.8%
Hyperuricaemia 0.7%
Diabetes Mellitus 0.7%
Dyspepsia 0.7%
Hypereosinophilic Syndrome 0.7%
Insomnia 0.7%
Chronic Graft Versus Host Disease 0.5%
Chronic Obstructive Pulmonary Disease 0.5%
Hypothyroidism 0.5%
Atrial Fibrillation 0.5%
Death 50.9%
Neoplasm Malignant 14.1%
Vomiting 3.8%
Pneumonia 3.3%
Thrombocytopenia 2.6%
Cd4 Lymphocytes Increased 2.4%
Pyrexia 2.4%
Renal Failure Chronic 2.2%
Drug Resistance 2.1%
Neoplasm Progression 2.1%
Sepsis 1.7%
Anaemia 1.5%
Drug Ineffective 1.5%
Dyspnoea 1.5%
Chronic Myeloid Leukaemia 1.4%
Gene Mutation Identification Test Positive 1.4%
Myocardial Infarction 1.4%
Therapeutic Response Decreased 1.4%
Blast Crisis In Myelogenous Leukaemia 1.2%
Nausea 1.2%
Secondary
Chronic Myeloid Leukaemia 31.3%
Acute Lymphocytic Leukaemia 22.5%
Gastrointestinal Stromal Tumour 9.0%
Prophylaxis 7.8%
Dyspepsia 4.1%
Pulmonary Arterial Hypertension 2.5%
Colorectal Cancer Stage Iv 2.3%
Non-hodgkin's Lymphoma 2.1%
Hypertension 2.0%
Immunosuppression 1.9%
Acute Myeloid Leukaemia 1.8%
Acute Myeloid Leukaemia Recurrent 1.8%
B Precursor Type Acute Leukaemia 1.8%
Product Used For Unknown Indication 1.8%
Chronic Graft Versus Host Disease 1.6%
Pain 1.4%
Graft Versus Host Disease 1.2%
Pulmonary Hypertension 1.1%
Aortic Valve Stenosis 1.0%
Nausea 1.0%
Death 11.3%
Neoplasm Malignant 9.1%
Pyrexia 7.4%
Blood Alkaline Phosphatase Increased 6.1%
Cd4 Lymphocytes Increased 6.1%
Skin Lesion 6.1%
Vomiting 5.6%
Acute Myeloid Leukaemia 5.2%
Nausea 4.8%
Chronic Myeloid Leukaemia 4.3%
Thrombocytopenia 4.3%
Scrotal Swelling 3.9%
Blood Creatinine Increased 3.5%
Hepatotoxicity 3.5%
Normal Newborn 3.5%
Pleural Effusion 3.5%
Cerebral Infarction 3.0%
Drug Ineffective 3.0%
Hallucination 3.0%
Pancytopenia 3.0%
Concomitant
Chronic Myeloid Leukaemia 16.6%
Acute Lymphocytic Leukaemia 12.5%
Respiratory Tract Infection 10.4%
Prophylaxis 9.0%
Nephrogenic Anaemia 7.6%
Stem Cell Transplant 5.2%
Chemotherapy 4.8%
Drug Use For Unknown Indication 3.5%
Asthma 3.1%
Acute Myeloid Leukaemia 2.8%
Acute Promyelocytic Leukaemia 2.8%
Bone Marrow Transplant 2.8%
Colorectal Cancer Metastatic 2.8%
Insomnia 2.8%
Parkinson's Disease 2.8%
Product Used For Unknown Indication 2.8%
Hypertension 2.1%
Idiopathic Thrombocytopenic Purpura 2.1%
Influenza 2.1%
Prophylaxis Against Graft Versus Host Disease 1.7%
White Blood Cell Count Decreased 9.4%
Aplastic Anaemia 7.8%
Angina Pectoris 6.3%
Hepatic Failure 6.3%
Rash 6.3%
Staphylococcal Infection 6.3%
Vomiting 6.3%
Acute Leukaemia 4.7%
Chronic Myeloid Leukaemia 4.7%
Pleural Effusion 4.7%
Pyrexia 4.7%
Spinal Compression Fracture 4.7%
Spinal Cord Disorder 4.7%
Stenotrophomonas Infection 4.7%
Cerebral Ischaemia 3.1%
Disseminated Intravascular Coagulation 3.1%
Fluid Retention 3.1%
Fusarium Infection 3.1%
Glioblastoma Multiforme 3.1%
Multi-organ Failure 3.1%
Interacting
Pulmonary Arterial Hypertension 36.4%
Chronic Myeloid Leukaemia 22.7%
Hypercholesterolaemia 22.7%
Hypokalaemia 9.1%
Acute Lymphocytic Leukaemia 4.5%
Stem Cell Transplant 4.5%
Blood Creatine Phosphokinase Increased 33.3%
Alanine Aminotransferase Increased 22.2%
Gastrointestinal Haemorrhage 22.2%
Drug Interaction 11.1%
Myositis 11.1%