Gemtuzumab Ozogamicin



Indications and Reactions:

Role Indications Reactions
Primary
Acute Myeloid Leukaemia 70.5%
Myelodysplastic Syndrome 13.1%
Acute Leukaemia 2.7%
Prophylaxis 1.9%
Pyrexia 1.5%
Febrile Neutropenia 1.1%
Hypertension 1.1%
Bone Pain 1.0%
Chemotherapy 0.9%
Acute Myeloid Leukaemia Recurrent 0.8%
Infection Prophylaxis 0.8%
Leukaemia 0.8%
Leukaemia Recurrent 0.8%
Drug Use For Unknown Indication 0.5%
Infection 0.5%
Myeloid Leukaemia 0.5%
Pain 0.5%
Antiemetic Supportive Care 0.4%
Neutropenia 0.4%
Acute Myeloid Leukemia 0.3%
Sepsis 15.2%
Neutropenic Sepsis 9.8%
Venoocclusive Liver Disease 8.8%
Thrombocytopenia 8.1%
Pneumonia 7.7%
Septic Shock 5.7%
Disease Progression 5.4%
Respiratory Failure 5.1%
Renal Failure 4.4%
Multi-organ Failure 3.7%
Myocardial Infarction 3.4%
Neutropenia 3.0%
Tachypnoea 3.0%
Lung Infection 2.7%
Gamma-glutamyltransferase Increased 2.4%
Hepatotoxicity 2.4%
Pulmonary Haemorrhage 2.4%
Respiratory Distress 2.4%
Tumour Lysis Syndrome 2.4%
Vomiting 2.4%
Secondary
Acute Myeloid Leukaemia 51.7%
Myelodysplastic Syndrome 22.8%
Product Used For Unknown Indication 8.1%
Prophylaxis 2.6%
Bone Pain 1.9%
Cord Blood Transplant Therapy 1.9%
Acute Promyelocytic Leukaemia 1.6%
Prophylaxis Against Graft Versus Host Disease 1.3%
Leukaemia Recurrent 1.2%
Pyrexia 1.1%
Premedication 1.0%
Acute Myeloid Leukemia 0.8%
Drug Use For Unknown Indication 0.7%
Acute Leukaemia 0.6%
Sepsis 0.5%
Acute Monocytic Leukaemia 0.5%
Antifungal Treatment 0.5%
Full Blood Count Decreased 0.5%
Acute Biphenotypic Leukaemia 0.4%
Acute Myeloid Leukemia Nos 0.4%
Sepsis 11.9%
Thrombocytopenia 10.9%
Venoocclusive Liver Disease 10.4%
Platelet Count Increased 7.8%
Infusion Related Reaction 5.7%
Respiratory Failure 5.7%
Alanine Aminotransferase Increased 4.1%
Convulsion 4.1%
Neutropenia 4.1%
Febrile Neutropenia 3.6%
Gamma-glutamyltransferase Increased 3.6%
Respiratory Distress 3.6%
Bronchopulmonary Aspergillosis 3.1%
Liver Disorder 3.1%
Neutropenic Sepsis 3.1%
Pancreatitis Acute 3.1%
Renal Failure 3.1%
Sinus Tachycardia 3.1%
Vaginal Haemorrhage 3.1%
Cardiac Arrest 2.6%
Concomitant
Acute Myeloid Leukaemia 18.4%
Cord Blood Transplant Therapy 14.3%
Prophylaxis Against Graft Versus Host Disease 10.2%
Prophylaxis 9.5%
Antifungal Prophylaxis 5.6%
Bone Marrow Conditioning Regimen 4.5%
Insomnia 4.0%
Liver Abscess 4.0%
Premedication 3.6%
Graft Versus Host Disease 3.3%
Allergy Prophylaxis 3.2%
Antibiotic Prophylaxis 2.8%
Neutropenia 2.8%
Acute Monocytic Leukaemia 2.6%
Product Used For Unknown Indication 2.5%
Febrile Neutropenia 2.0%
Acute Myeloid Leukaemia Recurrent 1.9%
Stem Cell Transplant 1.7%
Antiviral Prophylaxis 1.6%
Constipation Prophylaxis 1.6%
Venoocclusive Liver Disease 11.9%
Weight Increased 11.9%
Drug Ineffective 10.2%
White Blood Cell Count Decreased 10.2%
Platelet Count Decreased 6.8%
Respiratory Failure 6.8%
Blast Cells Present 5.1%
Petechiae 5.1%
Acute Myeloid Leukaemia Recurrent 3.4%
Cardiac Failure 3.4%
Cranial Nerve Disorder 3.4%
Disseminated Intravascular Coagulation 3.4%
Gastric Antral Vascular Ectasia 3.4%
Off Label Use 3.4%
Prothrombin Time Prolonged 3.4%
Asthenia 1.7%
Cholecystitis 1.7%
Colitis 1.7%
Diarrhoea 1.7%
Fatigue 1.7%