Deferasirox



Indications and Reactions:

Role Indications Reactions
Primary
Iron Overload 33.0%
Thalassaemia Beta 22.0%
Sickle Cell Anaemia 7.3%
Myelodysplastic Syndrome 6.4%
Zygomycosis 5.5%
Acute Myeloid Leukaemia 4.6%
Chelation Therapy 4.6%
Haemochromatosis 2.8%
Serum Ferritin Increased 2.8%
Anaemia 1.8%
Acute Monocytic Leukaemia 0.9%
Aplastic Anaemia 0.9%
Graft Versus Host Disease 0.9%
Hereditary Haemochromatosis 0.9%
Hypertension 0.9%
Hypothyroidism 0.9%
Lymphoma 0.9%
Myelofibrosis 0.9%
Pain 0.9%
Prophylaxis 0.9%
Vomiting 16.7%
Serum Ferritin Increased 11.1%
Nephrolithiasis 9.3%
Proteinuria 9.3%
Death 7.4%
Nausea 5.6%
Blood Urea Increased 3.7%
Creatinine Renal Clearance Decreased 3.7%
Hepatic Enzyme Increased 3.7%
Paraesthesia 3.7%
Thrombocytopenia 3.7%
Upper Gastrointestinal Haemorrhage 3.7%
Weight Increased 3.7%
Zygomycosis 3.7%
Abdominal Distension 1.9%
Abdominal Pain 1.9%
Alanine Aminotransferase Increased 1.9%
Aortic Aneurysm Rupture 1.9%
Blindness 1.9%
Blood Bilirubin Increased 1.9%
Secondary
Iron Overload 20.9%
Helicobacter Infection 18.0%
Thalassaemia Beta 13.4%
Aplastic Anaemia 5.8%
Myelodysplastic Syndrome 5.8%
Prophylaxis 5.8%
Chelation Therapy 5.2%
Product Used For Unknown Indication 3.5%
Acute Myeloid Leukaemia 2.3%
Antifungal Prophylaxis 2.3%
Drug Use For Unknown Indication 2.3%
Neutropenia 2.3%
Prophylaxis Against Gastrointestinal Ulcer 2.3%
Zygomycosis 2.3%
Sickle Cell Anaemia 1.7%
Acute Monocytic Leukaemia 1.2%
Antibiotic Prophylaxis 1.2%
Campylobacter Infection 1.2%
Helicobacter Pylori Infection 1.2%
Osteoporosis 1.2%
Vomiting 22.6%
Serum Ferritin Increased 21.0%
Acute Myeloid Leukaemia 6.5%
Pyrexia 6.5%
Glycosuria 4.8%
Transaminases Increased 4.8%
Cholecystitis 3.2%
Leukocytoclastic Vasculitis 3.2%
Pancreatitis 3.2%
Paraesthesia 3.2%
Peripheral Sensory Neuropathy 3.2%
Sudden Death 3.2%
Weight Increased 3.2%
Aspartate Aminotransferase Increased 1.6%
Asthenia 1.6%
Cardiac Siderosis 1.6%
Fatigue 1.6%
Growth Hormone Deficiency 1.6%
Headache 1.6%
Hepatic Neoplasm Malignant 1.6%
Concomitant
Prophylaxis 20.1%
Aplastic Anaemia 18.3%
Product Used For Unknown Indication 9.5%
Infection Prophylaxis 8.9%
Premedication 6.9%
Bone Marrow Conditioning Regimen 4.1%
Iron Overload 3.9%
Chronic Obstructive Pulmonary Disease 3.4%
Myelodysplastic Syndrome 3.0%
Prophylaxis Against Gastrointestinal Ulcer 2.7%
Prophylaxis Against Graft Versus Host Disease 2.7%
Osteoporosis 2.6%
Acute Myeloid Leukaemia 2.1%
Constipation 2.1%
Sickle Cell Anaemia 2.0%
Antifungal Prophylaxis 1.8%
Hypertension 1.7%
Antiviral Prophylaxis 1.6%
Gastritis Prophylaxis 1.3%
Insomnia 1.3%
Pneumonia 14.1%
Therapeutic Response Decreased 8.2%
Lung Squamous Cell Carcinoma Stage Unspecified 7.1%
Neutropenia 7.1%
White Blood Cell Count Decreased 7.1%
Sickle Cell Anaemia With Crisis 5.9%
Death 4.7%
Febrile Neutropenia 4.7%
Lung Squamous Cell Carcinoma Stage 0 4.7%
Pyrexia 4.7%
Thrombocytopenia 4.7%
Sepsis 3.5%
Transfusion Reaction 3.5%
Tumour Lysis Syndrome 3.5%
Vomiting 3.5%
White Blood Cell Count Increased 3.5%
Abdominal Pain Upper 2.4%
Cachexia 2.4%
Cystitis Haemorrhagic 2.4%
Diarrhoea 2.4%
Interacting
Cardiac Failure 100.0%
Renal Failure Acute 100.0%