Decitabine



Indications and Reactions:

Role Indications Reactions
Primary
Acute Myeloid Leukaemia 42.9%
Myelodysplastic Syndrome 34.1%
Mds 3.6%
Myeloid Leukaemia 3.4%
Chronic Myelomonocytic Leukaemia 1.7%
Product Used For Unknown Indication 1.7%
Acute Myeloid Leukaemia Recurrent 1.5%
Colon Cancer Metastatic 1.5%
Colorectal Cancer Metastatic 1.5%
Infection Prophylaxis 1.5%
Sarcoma 1.5%
Rectal Cancer Metastatic 1.0%
Acute Myelomonocytic Leukaemia 0.7%
Colorectal Cancer 0.7%
Neoplasm 0.7%
Acute Myeloid Leukemia 0.5%
Malignant Melanoma 0.5%
Metastatic Malignant Melanoma 0.5%
Salvage Therapy 0.5%
Acute Myeloid Leukaemia 0.2%
Pyrexia 22.7%
Febrile Neutropenia 9.9%
Thrombocytopenia 8.5%
Haematotoxicity 6.4%
Pneumonia 6.4%
Infection 5.0%
Respiratory Failure 4.3%
White Blood Cell Count Decreased 4.3%
Neutropenia 3.5%
Sepsis 3.5%
Septic Shock 3.5%
Acute Myeloid Leukaemia 2.8%
Bacterial Infection 2.8%
Caecitis 2.8%
Electrocardiogram Qt Prolonged 2.8%
Anaemia 2.1%
Anal Infection 2.1%
Gastrointestinal Haemorrhage 2.1%
Lung Infection 2.1%
Off Label Use 2.1%
Secondary
Myelodysplastic Syndrome 33.5%
Stem Cell Transplant 16.6%
Acute Myeloid Leukaemia 14.4%
Prophylaxis Against Graft Versus Host Disease 14.0%
Product Used For Unknown Indication 7.7%
Drug Use For Unknown Indication 3.1%
Infection Prophylaxis 2.5%
Metastatic Malignant Melanoma 1.8%
Acute Lymphocytic Leukaemia 1.1%
Diffuse Large B-cell Lymphoma 1.1%
Erythroleukaemia 0.6%
Febrile Neutropenia 0.5%
Thrombocytopenia 0.5%
Acute Leukaemia 0.4%
Bone Sarcoma 0.4%
Colorectal Cancer 0.4%
Pain 0.4%
Paroxysmal Nocturnal Haemoglobinuria 0.4%
Serum Ferritin Increased 0.4%
Abdominal Pain Upper 0.3%
Diarrhoea 21.5%
Nausea 7.6%
Chronic Graft Versus Host Disease 7.0%
Thrombocytopenia 7.0%
Mucosal Inflammation 6.3%
White Blood Cell Count Decreased 6.3%
Febrile Neutropenia 4.4%
Sepsis 4.4%
Multi-organ Failure 3.8%
Staphylococcal Bacteraemia 3.8%
Death 3.2%
Pyrexia 3.2%
Vomiting 3.2%
Weight Decreased 3.2%
Anaphylactic Reaction 2.5%
Myelodysplastic Syndrome Transformation 2.5%
Nervous System Disorder 2.5%
Platelet Count Decreased 2.5%
Weight Increased 2.5%
White Blood Cell Count Increased 2.5%
Concomitant
Product Used For Unknown Indication 24.1%
Myelodysplastic Syndrome 13.8%
Drug Use For Unknown Indication 11.6%
Acute Myeloid Leukaemia 9.9%
Prophylaxis 5.6%
Iron Overload 5.4%
Hypertension 4.9%
Anaemia 2.8%
Pain 2.8%
Colon Cancer Metastatic 2.4%
Haematopoietic Stem Cell Mobilisation 2.4%
Idiopathic Thrombocytopenic Purpura 1.9%
Thrombosis Prophylaxis 1.9%
Dementia Alzheimer's Type 1.7%
Paroxysmal Nocturnal Haemoglobinuria 1.7%
Glaucoma 1.5%
Insomnia 1.5%
Plasma Cell Leukaemia 1.5%
Refractory Anaemia With An Excess Of Blasts 1.5%
Prophylaxis Against Graft Versus Host Disease 1.3%
Febrile Neutropenia 10.3%
Pancytopenia 8.8%
Platelet Count Decreased 8.8%
Vomiting 8.8%
Acute Myeloid Leukaemia 5.9%
Drug Ineffective 5.9%
No Therapeutic Response 5.9%
Death 4.4%
Dyspnoea 4.4%
Pneumonia 4.4%
Prostate Cancer 4.4%
Respiratory Failure 4.4%
Chills 2.9%
Emotional Distress 2.9%
Gastrointestinal Haemorrhage 2.9%
Hypotension 2.9%
Mental Status Changes 2.9%
Myelodysplastic Syndrome 2.9%
Presyncope 2.9%
Pyrexia 2.9%