Dacarbazine



Indications and Reactions:

Role Indications Reactions
Primary
Malignant Melanoma 24.6%
Drug Use For Unknown Indication 20.2%
Hodgkin's Disease 19.6%
Metastatic Malignant Melanoma 16.0%
Malignant Melanoma Stage Iv 5.8%
Multiple Myeloma 2.7%
Hodgkin's Disease Nodular Sclerosis Stage Unspecified 1.6%
Non-hodgkin's Lymphoma 1.6%
Hypertension 1.2%
Pain 0.9%
Lymphoma 0.8%
Hodgkin's Disease Nodular Sclerosis Stage Ii 0.6%
Hodgkin's Lymphoma 0.6%
Neuroblastoma 0.6%
Prophylactic Chemotherapy 0.6%
Unevaluable Event 0.6%
Hodgkin's Disease Recurrent 0.5%
Hodgkin's Disease Stage Iii 0.5%
Pneumonia 0.5%
Rhabdomyosarcoma 0.5%
Pyrexia 11.9%
Thrombocytopenia 11.3%
Pulmonary Embolism 6.5%
Vomiting 6.5%
Metastatic Malignant Melanoma 6.0%
Ureteric Obstruction 5.4%
Pulmonary Toxicity 4.8%
Disease Progression 4.2%
Overdose 4.2%
Pneumonia 4.2%
Staphylococcal Infection 4.2%
Syncope 4.2%
Febrile Neutropenia 3.6%
Hypertension 3.6%
Malignant Melanoma 3.6%
Pleural Effusion 3.6%
Renal Failure 3.6%
Acute Lymphocytic Leukaemia 3.0%
Neutropenia 3.0%
Tumour Lysis Syndrome 3.0%
Secondary
Hodgkin's Disease 56.9%
Non-hodgkin's Lymphoma 4.6%
Metastatic Malignant Melanoma 4.5%
Malignant Melanoma 3.8%
Lung Neoplasm Malignant 3.4%
Breast Cancer 3.3%
Malignant Melanoma Stage Iv 3.2%
Metastases To Lung 2.6%
Sarcoma 2.6%
Synovial Sarcoma 2.5%
Lymphoma 2.1%
Product Used For Unknown Indication 1.8%
Neuroblastoma 1.8%
Drug Use For Unknown Indication 1.6%
Pain 1.1%
Haematological Malignancy 1.0%
Hodgkin's Disease Recurrent 0.9%
Nausea 0.8%
Hypertension 0.8%
Foetal Exposure During Pregnancy 0.7%
Pulmonary Toxicity 20.5%
Febrile Neutropenia 6.1%
Hypothyroidism 6.1%
Toxicity To Various Agents 6.1%
Myelodysplastic Syndrome 5.8%
Thrombocytopenia 5.1%
Pulmonary Embolism 4.8%
Pyrexia 4.8%
Off Label Use 4.6%
Sepsis 4.6%
White Blood Cell Count Decreased 4.6%
Acute Myeloid Leukaemia 4.3%
Pneumonia 3.5%
Death 3.3%
Neutropenia 2.8%
Platelet Count Decreased 2.8%
Vomiting 2.8%
Asthenia 2.5%
Diffuse Large B-cell Lymphoma 2.5%
Pancytopenia 2.5%
Concomitant
Hodgkin's Disease 27.8%
Chemotherapy 11.2%
Hiv Infection 6.1%
Chronic Lymphocytic Leukaemia 5.4%
Eczema 5.4%
Malignant Melanoma 5.4%
Product Used For Unknown Indication 4.3%
Drug Use For Unknown Indication 4.2%
Lymphoma 3.9%
Pseudolymphoma 3.9%
Metastatic Malignant Melanoma 3.3%
Neutropenia 3.3%
Non-hodgkin's Lymphoma 3.2%
Hodgkin's Disease Stage Iii 3.0%
Angioimmunoblastic T-cell Lymphoma 2.2%
Nausea 1.7%
Prophylaxis 1.7%
Sarcoma 1.5%
Bone Marrow Transplant 1.2%
Vomiting 1.2%
Weight Decreased 8.2%
Febrile Neutropenia 7.3%
Pulmonary Toxicity 7.3%
Interstitial Lung Disease 6.4%
Neutropenia 5.5%
Pulmonary Fibrosis 5.5%
Tachycardia 5.5%
Vomiting 5.5%
Wound Infection 5.5%
Rash 4.5%
Scoliosis 4.5%
Vasogenic Cerebral Oedema 4.5%
White Blood Cell Count Decreased 4.5%
Chronic Lymphocytic Leukaemia 3.6%
Disease Progression 3.6%
Dyspnoea 3.6%
Exposure During Pregnancy 3.6%
Neurotoxicity 3.6%
Pneumonitis 3.6%
Pulmonary Haemorrhage 3.6%
Interacting
Hodgkin's Disease 30.8%
Metastatic Malignant Melanoma 30.8%
Hiv Infection 23.1%
Brain Oedema 7.7%
Convulsion 7.7%
Drug Level Decreased 50.0%
Pyrexia 50.0%