Crizotinib



Indications and Reactions:

Role Indications Reactions
Primary
Non-small Cell Lung Cancer 29.2%
Hypertension 9.7%
Constipation 8.7%
Pain 8.5%
Nausea 7.8%
Prophylaxis 5.6%
Insomnia 3.0%
Diarrhoea 2.9%
Back Pain 2.7%
Lung Neoplasm Malignant 2.6%
Anxiety 2.4%
Supplementation Therapy 2.4%
Cough 2.1%
Chronic Obstructive Pulmonary Disease 1.9%
Vomiting 1.9%
Diabetes Mellitus 1.8%
Gastrooesophageal Reflux Disease 1.8%
Pulmonary Embolism 1.8%
Hyperlipidaemia 1.7%
Hypothyroidism 1.7%
Death 22.8%
Interstitial Lung Disease 11.3%
Non-small Cell Lung Cancer 6.3%
Cytolytic Hepatitis 6.0%
Pulmonary Embolism 5.0%
Neoplasm Malignant 4.6%
Respiratory Failure 4.6%
Disease Progression 4.0%
Vomiting 4.0%
Dehydration 3.3%
Hepatotoxicity 3.3%
Deep Vein Thrombosis 3.0%
Dyspnoea 3.0%
Hyponatraemia 3.0%
Convulsion 2.6%
Diarrhoea 2.6%
Haemoptysis 2.6%
Nausea 2.6%
Pneumonia 2.6%
Renal Failure Acute 2.6%
Secondary
Non-small Cell Lung Cancer 22.3%
Pain 11.7%
Constipation 11.0%
Hypertension 6.5%
Nausea 6.3%
Gastrointestinal Pain 5.9%
Product Used For Unknown Indication 4.1%
Insomnia 3.3%
Anxiety 3.0%
Back Pain 2.8%
Hyperlipidaemia 2.6%
Prophylaxis 2.6%
Supplementation Therapy 2.6%
Hypothyroidism 2.4%
Vomiting 2.4%
Depression 2.2%
Gastrooesophageal Reflux Disease 2.2%
Bronchial Carcinoma 2.0%
Lung Adenocarcinoma Metastatic 2.0%
Diarrhoea 1.9%
Hepatic Function Abnormal 9.3%
Gastric Ulcer 8.1%
Transaminases Increased 8.1%
Non-small Cell Lung Cancer 7.0%
Pneumonia 7.0%
Urinary Tract Infection 7.0%
Cytolytic Hepatitis 5.8%
Lower Respiratory Tract Infection 4.7%
Oedema Peripheral 4.7%
Orthostatic Hypotension 4.7%
Basal Cell Carcinoma 3.5%
Decreased Appetite 3.5%
Diarrhoea Haemorrhagic 3.5%
Gastritis 3.5%
Interstitial Lung Disease 3.5%
Large Intestine Perforation 3.5%
Pleural Effusion 3.5%
Viral Infection 3.5%
Visual Acuity Reduced 3.5%
Autoimmune Hepatitis 2.3%
Concomitant
Non-small Cell Lung Cancer 17.5%
Lung Neoplasm Malignant 15.8%
Drug Use For Unknown Indication 12.3%
Product Used For Unknown Indication 12.3%
Multiple Myeloma 8.8%
Gastrointestinal Carcinoma 7.0%
Deep Vein Thrombosis 3.5%
Metastases To Bone 3.5%
Nausea 3.5%
Prophylaxis 3.5%
Transient Ischaemic Attack 3.5%
Constipation 1.8%
Hypotension 1.8%
Mineral Supplementation 1.8%
Pain 1.8%
Thromboembolism Prophylaxis 1.8%
Haematoma 20.0%
Vision Blurred 20.0%
Hypocalcaemia 10.0%
Metastasis 10.0%
Off Label Use 10.0%
Urinary Retention 10.0%
Vomiting 10.0%
White Blood Cell Count Decreased 10.0%
Interacting
Angiogram 39.3%
Non-small Cell Lung Cancer 39.3%
Bipolar I Disorder 7.1%
Depression 7.1%
Neoplasm Malignant 7.1%
Drug Interaction 38.5%
Sinus Bradycardia 38.5%
Multi-organ Failure 15.4%
Electrocardiogram Qt Prolonged 7.7%