Bosentan



Indications and Reactions:

Role Indications Reactions
Primary
Pulmonary Arterial Hypertension 60.0%
Pulmonary Hypertension 14.3%
Endocarditis 5.7%
Product Used For Unknown Indication 5.7%
Staphylococcal Infection 5.7%
Connective Tissue Disorder 2.9%
Digital Ulcer 2.9%
Maternal Exposure During Pregnancy 2.9%
Vomiting 17.4%
Fatigue 8.7%
Hypoaesthesia 8.7%
Normal Newborn 8.7%
Biliary Dyskinesia 4.3%
Death 4.3%
Dehydration 4.3%
Fall 4.3%
Haemoglobin Decreased 4.3%
Loss Of Consciousness 4.3%
Nausea 4.3%
Pneumonia 4.3%
Pulmonary Arterial Pressure Increased 4.3%
Red Blood Cell Sedimentation Rate Increased 4.3%
Rickets 4.3%
Staphylococcal Sepsis 4.3%
Weight Increased 4.3%
Secondary
Pulmonary Arterial Hypertension 37.0%
Pulmonary Hypertension 26.1%
Drug Use For Unknown Indication 8.1%
Nonketotic Hyperglycinaemia 3.0%
Scleroderma 3.0%
Systemic Sclerosis 3.0%
Hiv Infection 2.5%
Product Used For Unknown Indication 2.3%
Eisenmenger's Syndrome 1.8%
Angiopathy 1.5%
Dermatitis Atopic 1.5%
Infection 1.5%
Interstitial Lung Disease 1.5%
Ventricular Septal Defect 1.5%
Coagulopathy 1.0%
Infection Prophylaxis 1.0%
Ischaemia 1.0%
Sclerodactylia 1.0%
Atrial Fibrillation 0.8%
Cardiac Failure 0.8%
Sepsis 17.2%
Liver Disorder 9.7%
Pulmonary Hypertension 7.5%
Platelet Count Decreased 6.5%
Pulmonary Oedema 6.5%
Tricuspid Valve Incompetence 6.5%
Unresponsive To Stimuli 6.5%
Death 4.3%
Ventricular Tachycardia 4.3%
Vitreous Haemorrhage 4.3%
Cardiac Failure 3.2%
Drug Interaction 3.2%
Hypoxia 3.2%
Urticaria 3.2%
Vomiting 3.2%
Hypertransaminasaemia 2.2%
Hypoaesthesia 2.2%
Pericardial Effusion 2.2%
Pneumonia 2.2%
Right Ventricular Failure 2.2%
Concomitant
Pulmonary Arterial Hypertension 26.1%
Pulmonary Hypertension 25.7%
Drug Use For Unknown Indication 13.0%
Product Used For Unknown Indication 12.4%
Systemic Lupus Erythematosus 5.9%
Oedema 2.2%
Hypertension 2.0%
Rheumatoid Arthritis 1.4%
Scleroderma 1.4%
Depression 1.2%
Fibrinous Bronchitis 1.2%
Osteoporosis 1.1%
Hepatitis C 0.9%
Hypothyroidism 0.9%
Pulmonary Embolism 0.9%
Anaemia 0.8%
Mixed Connective Tissue Disease 0.8%
Anticoagulant Therapy 0.7%
Anxiety 0.7%
Asthma 0.7%
Right Ventricular Failure 10.6%
Pulmonary Hypertension 9.1%
Visual Acuity Reduced 8.3%
Vomiting 8.3%
Pulmonary Arterial Hypertension 6.1%
Death 5.3%
Respiratory Failure 5.3%
Pneumonia 4.5%
Progressive Multifocal Leukoencephalopathy 4.5%
Dyspnoea 3.8%
Renal Failure Acute 3.8%
Supraventricular Tachycardia 3.8%
Tremor 3.8%
Weight Decreased 3.8%
Weight Increased 3.8%
Drug Ineffective 3.0%
Fatigue 3.0%
Osteonecrosis 3.0%
Subdural Haematoma 3.0%
Thrombocytopenia 3.0%
Interacting
Pulmonary Arterial Hypertension 29.2%
Hepatitis C 12.5%
Chronic Obstructive Pulmonary Disease 8.3%
Contraception 8.3%
Endocarditis 8.3%
Hepatitis B 8.3%
Hiv Infection 8.3%
Superinfection 8.3%
Arthropathy 4.2%
Pulmonary Hypertension 4.2%
Liver Disorder 18.2%
Liver Injury 18.2%
Unintended Pregnancy 18.2%
Hepatotoxicity 9.1%
Off Label Use 9.1%
Pulmonary Arterial Pressure Increased 9.1%
Thrombocytopenia 9.1%
White Blood Cell Count Decreased 9.1%