Blinded Sorafenib (Raf Kinase Inhibitor)

Role

Indications

Reactions

Primary

Hepatic Neoplasm Malignant	21.0%
Hypertension	15.2%
Prophylaxis	7.6%
Diabetes Mellitus	4.8%
Diagnostic Procedure	4.8%
Abdominal Distension	4.5%
Diarrhoea	4.5%
Nephrotic Syndrome	4.1%
Insomnia	3.8%
Nausea	3.8%
Chronic Obstructive Pulmonary Disease	3.4%
Rash	3.4%
Gastrointestinal Disorder	3.1%
Metastatic Ocular Melanoma	2.8%
Urosepsis	2.8%
Dermatitis	2.1%
Palmar-plantar Erythrodysaesthesia Syndrome	2.1%
Paronychia	2.1%
Postoperative Care	2.1%
Scan With Contrast	2.1%

Cardiac Arrest	11.1%
Diarrhoea	8.3%
Hepatic Failure	8.3%
Nephrotic Syndrome	8.3%
Abdominal Distension	5.6%
Bladder Neoplasm	5.6%
Confusional State	5.6%
Hepatic Haemorrhage	5.6%
Oesophageal Varices Haemorrhage	5.6%
Palmar-plantar Erythrodysaesthesia Syndrome	5.6%
Vascular Neoplasm	5.6%
Abdominal Pain	2.8%
Alanine Aminotransferase Increased	2.8%
Bradycardia	2.8%
C-reactive Protein Increased	2.8%
Death	2.8%
Dyspnoea	2.8%
Emphysematous Pyelonephritis	2.8%
Fatigue	2.8%
Gastrointestinal Stromal Tumour	2.8%

Secondary

Hepatic Neoplasm Malignant	18.7%
Dehydration	10.4%
Hypertension	9.5%
Insomnia	8.7%
Abdominal Pain Upper	7.6%
Abdominal Pain	6.9%
Diagnostic Procedure	6.1%
Prophylaxis	5.7%
Diarrhoea	4.0%
Prophylaxis Of Nausea And Vomiting	3.5%
Constipation	2.7%
Pain	2.6%
Thyroid Cancer	2.3%
Breast Mass	2.1%
Computerised Tomogram	2.0%
Diabetes Mellitus	2.0%
Sedation	1.5%
Infection	1.4%
Mucosal Inflammation	1.4%
Blood Thyroid Stimulating Hormone Increased	1.1%

Diarrhoea	18.4%
Abdominal Pain Upper	16.4%
Bladder Neoplasm	10.0%
Staphylococcal Infection	8.0%
Lung Disorder	6.5%
Enterobacter Infection	5.0%
Hepatic Failure	4.5%
Lower Gastrointestinal Haemorrhage	4.5%
Varices Oesophageal	4.0%
Gastrointestinal Haemorrhage	3.0%
Hepatic Encephalopathy	3.0%
Interstitial Lung Disease	3.0%
Pericardial Effusion	2.5%
Pneumonia	2.5%
Cholangitis	2.0%
Alanine Aminotransferase Increased	1.5%
Ascites	1.5%
Hyponatraemia	1.5%
Palmar-plantar Erythrodysaesthesia Syndrome	1.5%
Abdominal Distension	1.0%